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The map label for this gene is frc [H]

Identifier: 94311063

GI number: 94311063

Start: 2306754

End: 2307950

Strand: Reverse

Name: frc [H]

Synonym: Rmet_2125

Alternate gene names: 94311063

Gene position: 2307950-2306754 (Counterclockwise)

Preceding gene: 94311064

Following gene: 94311062

Centisome position: 58.76

GC content: 66.42

Gene sequence:

>1197_bases
ATGGCGCGACAGATTCTCGACGGCATCCGCGTTCTCGAACTGGGCCAGCTGATTGCAGGCCCCTTTGCCGCCAAGACACT
TGCCGATTTCGGCGCACACGTGGTCAAGGTGGAGCCGCCCGGGCAGGGCGATCCGCTGCGAAAGTGGCGCATGTTGCACG
AAGATACCTCGGTCTGGTGGGAAGCCCAGTCGCGCAACAAGCAGTCGATTGCCATCGACCTGCGCCAGCCGGAGGGGCAG
GCTCTGGTACGCAAGCTGGCCAGCGAGGCCGACGTCCTGATCGAGAACTTCCGCCCGGGAACCATGGAGAAATGGGGGCT
CGGCTGGGATGTGCTTCATGCCGACAATCCAAAGCTGATCATGGTGCGGGTCTCGGGCTACGGCCAGAGCGGCCCGAAGC
GGGATGAGCCCGGCTTTGCGGCGGTGGCCGAAGCGATGAGCGGGCTGCGCTACCTGACCGGCGAGCCTGGACGCCCGCCC
GTGCGCGCGGGCTTGTCGCTGGGTGACACGATCGCCGGCCTGCATGGCGCGCTTGGCGTGCTGCTGGCGCTGTACGAACG
CGATGCGCGTGGTGGTAAAGGCCAGGTCATCGACGTGGCGCTGTATGAGTCGCTGTTCAATCTGAGCGAAAGCCTGTTGC
CCGAGTACTCCGCGTTCGGCGCTGTGCGCCAGCCGGCCGGGGGTGCCTTGCCGGGAATCGCGCCGTCGAATGCCTACCTG
TGCGGCTGCGGCGAGTATGTGCTGATCGCCGCCAACGGCGACGCGATCTTCCGCCGCCTGATGGCCGCGATGGGTCGCAA
CGACCTGGGCGAAGACCCGGCGCTGGCACGCAATGATGGCCGCGTGAAGCGTGTCGACGAGATCGATGCCGCGATTACCG
CCTGGACGAAGACACAAACCGTGGCCTCCGCGCTGGAAGTGCTGCGTACCGCCGACGTGCCGTCTGGCCGCATCTACACC
GTCAAGGACATTGCCGAAGACCCGCACTACCGGGCGCGCGGCGTAATCGAGACGGTGACATCCGCGAAGGGCCTGCAGGT
GGAGGTGCCAGGCATCATGCCGAAGCTGTCGGGCAATCCCGGCGGCATCCACGATCGCGCGCCGACGCTGGGCGAGCATA
CCGATTCCGTGCTGGCCGATGCCGGCTTCGACGCGGCGGCCATTGCCGACCTGCGTAATCGCGGAGTGATTGCATGA

Upstream 100 bases:

>100_bases
CTTTCCGGAATGCCGATTCCGCATCACCCCGCCGCTGGGGCACACTCCGTCGAAACTACGCCAATCCACCCCAATCGGGG
TCAGTTTCTCGGAGACACTC

Downstream 100 bases:

>100_bases
GTGCCAAGATGAGTGCTGCTACGTATCCGCTGTCAGGCCCGGCGAAGGTCGAGATCAACGAAGTCGCCCCGCGCGACGGG
CTGCAGATCGAACCGTTCAT

Product: L-carnitine dehydratase/bile acid-inducible protein

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MARQILDGIRVLELGQLIAGPFAAKTLADFGAHVVKVEPPGQGDPLRKWRMLHEDTSVWWEAQSRNKQSIAIDLRQPEGQ
ALVRKLASEADVLIENFRPGTMEKWGLGWDVLHADNPKLIMVRVSGYGQSGPKRDEPGFAAVAEAMSGLRYLTGEPGRPP
VRAGLSLGDTIAGLHGALGVLLALYERDARGGKGQVIDVALYESLFNLSESLLPEYSAFGAVRQPAGGALPGIAPSNAYL
CGCGEYVLIAANGDAIFRRLMAAMGRNDLGEDPALARNDGRVKRVDEIDAAITAWTKTQTVASALEVLRTADVPSGRIYT
VKDIAEDPHYRARGVIETVTSAKGLQVEVPGIMPKLSGNPGGIHDRAPTLGEHTDSVLADAGFDAAAIADLRNRGVIA

Sequences:

>Translated_398_residues
MARQILDGIRVLELGQLIAGPFAAKTLADFGAHVVKVEPPGQGDPLRKWRMLHEDTSVWWEAQSRNKQSIAIDLRQPEGQ
ALVRKLASEADVLIENFRPGTMEKWGLGWDVLHADNPKLIMVRVSGYGQSGPKRDEPGFAAVAEAMSGLRYLTGEPGRPP
VRAGLSLGDTIAGLHGALGVLLALYERDARGGKGQVIDVALYESLFNLSESLLPEYSAFGAVRQPAGGALPGIAPSNAYL
CGCGEYVLIAANGDAIFRRLMAAMGRNDLGEDPALARNDGRVKRVDEIDAAITAWTKTQTVASALEVLRTADVPSGRIYT
VKDIAEDPHYRARGVIETVTSAKGLQVEVPGIMPKLSGNPGGIHDRAPTLGEHTDSVLADAGFDAAAIADLRNRGVIA
>Mature_397_residues
ARQILDGIRVLELGQLIAGPFAAKTLADFGAHVVKVEPPGQGDPLRKWRMLHEDTSVWWEAQSRNKQSIAIDLRQPEGQA
LVRKLASEADVLIENFRPGTMEKWGLGWDVLHADNPKLIMVRVSGYGQSGPKRDEPGFAAVAEAMSGLRYLTGEPGRPPV
RAGLSLGDTIAGLHGALGVLLALYERDARGGKGQVIDVALYESLFNLSESLLPEYSAFGAVRQPAGGALPGIAPSNAYLC
GCGEYVLIAANGDAIFRRLMAAMGRNDLGEDPALARNDGRVKRVDEIDAAITAWTKTQTVASALEVLRTADVPSGRIYTV
KDIAEDPHYRARGVIETVTSAKGLQVEVPGIMPKLSGNPGGIHDRAPTLGEHTDSVLADAGFDAAAIADLRNRGVIA

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=394, Percent_Identity=29.9492385786802, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI300863124, Length=420, Percent_Identity=29.2857142857143, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI42794625, Length=397, Percent_Identity=33.5012594458438, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI266456254, Length=397, Percent_Identity=33.5012594458438, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI300863126, Length=394, Percent_Identity=27.6649746192893, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI266458393, Length=264, Percent_Identity=39.0151515151515, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI266458397, Length=209, Percent_Identity=43.0622009569378, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI13376042, Length=420, Percent_Identity=26.6666666666667, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI266458395, Length=126, Percent_Identity=46.8253968253968, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI42822893, Length=126, Percent_Identity=46.8253968253968, Blast_Score=106, Evalue=5e-23,
Organism=Escherichia coli, GI87082093, Length=355, Percent_Identity=32.112676056338, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1788717, Length=418, Percent_Identity=28.7081339712919, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786222, Length=399, Percent_Identity=26.5664160401003, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI115535051, Length=278, Percent_Identity=31.6546762589928, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI32564160, Length=215, Percent_Identity=33.953488372093, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24648431, Length=399, Percent_Identity=32.5814536340852, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24585488, Length=200, Percent_Identity=39, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 42434; Mature: 42303

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQILDGIRVLELGQLIAGPFAAKTLADFGAHVVKVEPPGQGDPLRKWRMLHEDTSVWW
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCEE
EAQSRNKQSIAIDLRQPEGQALVRKLASEADVLIENFRPGTMEKWGLGWDVLHADNPKLI
ECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCEEEEECCCCCEE
MVRVSGYGQSGPKRDEPGFAAVAEAMSGLRYLTGEPGRPPVRAGLSLGDTIAGLHGALGV
EEEEECCCCCCCCCCCCHHHHHHHHHHCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHH
LLALYERDARGGKGQVIDVALYESLFNLSESLLPEYSAFGAVRQPAGGALPGIAPSNAYL
HHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCEE
CGCGEYVLIAANGDAIFRRLMAAMGRNDLGEDPALARNDGRVKRVDEIDAAITAWTKTQT
EECCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
VASALEVLRTADVPSGRIYTVKDIAEDPHYRARGVIETVTSAKGLQVEVPGIMPKLSGNP
HHHHHHHHHHCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
GGIHDRAPTLGEHTDSVLADAGFDAAAIADLRNRGVIA
CCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
ARQILDGIRVLELGQLIAGPFAAKTLADFGAHVVKVEPPGQGDPLRKWRMLHEDTSVWW
CHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCEE
EAQSRNKQSIAIDLRQPEGQALVRKLASEADVLIENFRPGTMEKWGLGWDVLHADNPKLI
ECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCEEEEECCCCCEE
MVRVSGYGQSGPKRDEPGFAAVAEAMSGLRYLTGEPGRPPVRAGLSLGDTIAGLHGALGV
EEEEECCCCCCCCCCCCHHHHHHHHHHCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHH
LLALYERDARGGKGQVIDVALYESLFNLSESLLPEYSAFGAVRQPAGGALPGIAPSNAYL
HHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCEE
CGCGEYVLIAANGDAIFRRLMAAMGRNDLGEDPALARNDGRVKRVDEIDAAITAWTKTQT
EECCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
VASALEVLRTADVPSGRIYTVKDIAEDPHYRARGVIETVTSAKGLQVEVPGIMPKLSGNP
HHHHHHHHHHCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
GGIHDRAPTLGEHTDSVLADAGFDAAAIADLRNRGVIA
CCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA