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The map label for this gene is cbbI2 [H]

Identifier: 94311026

GI number: 94311026

Start: 2267396

End: 2268082

Strand: Reverse

Name: cbbI2 [H]

Synonym: Rmet_2088

Alternate gene names: 94311026

Gene position: 2268082-2267396 (Counterclockwise)

Preceding gene: 94311028

Following gene: 94311023

Centisome position: 57.74

GC content: 63.17

Gene sequence:

>687_bases
ATGACTCAGGATGAACTCAAGGCGCTGGTCGCGCAAGCTGCCGCTGACTATGTGAAGCAGGAAGTGCCCGAAGGCGCCGT
TCTCGGCGTGGGCACCGGCTCCACCGCCAATCTCTTCATCGACGCCGTGGCGGCGTTCAAGGAGCGCTTTTCGGGCGCGG
TGTCGAGTTCCGAGGCCTCCACACGCCGCTTGCAACAGCACGGTTTCAATGTGCTCGATCTGAACGAGGTCGACAGCATT
CCCGTCTATGTCGACGGTGCTGACGAGATCGACAACTCGGGCGCGATGATCAAGGGCGGCGGCGGTGCGCTGACGCGCGA
GAAGATCGTTGCCTCGGTGGCGGACCGATTCGTCTGCATTGCCGACGGCAGCAAGCTGGTGCCGACGATGGGCGCGTTTC
CGCTGCCGGTCGAGGTGATCCCGATGGCACGCGCAGCGGTGGCCCGTAGCCTGGCGGCACTAGGCGGTCAGCCGCGTCTG
CGCATGACCAAGGAAGGCGGCATCTACAAGACCGACAACGGCAACGTCATTCTGGATGTCTCGGGCCTGAAGATCGAGAA
CCCGAAGGCGCTGGAGCAGCAAATCAACCAGCTACCCGGCGTGGTGACCGTTGGTCTGTTCGCTCTGCGCGGAGCAAATG
TGCTGTTGCTGGGTACCGAACAGGGCGTGCAGCGCTCGGATTACTGA

Upstream 100 bases:

>100_bases
GGAGGGGCCATTGTAACGGCGTGGCGCGTGGCGTAAACGTCGGAGATGGGGAACCAATCCGCTACACTACGCGTTTCCCA
ACGCTTTTCTGGCTGTAGTC

Downstream 100 bases:

>100_bases
ATCGCATAAGCGTCGTATGAGTGAGAGGCCGGGCGGTGATGGCCCCCCGGCTTCGAATGCCTCACGCGGTGAGCCCATGC
TCCACTGCGTAGACGGCCAC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKERFSGAVSSSEASTRRLQQHGFNVLDLNEVDSI
PVYVDGADEIDNSGAMIKGGGGALTREKIVASVADRFVCIADGSKLVPTMGAFPLPVEVIPMARAAVARSLAALGGQPRL
RMTKEGGIYKTDNGNVILDVSGLKIENPKALEQQINQLPGVVTVGLFALRGANVLLLGTEQGVQRSDY

Sequences:

>Translated_228_residues
MTQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKERFSGAVSSSEASTRRLQQHGFNVLDLNEVDSI
PVYVDGADEIDNSGAMIKGGGGALTREKIVASVADRFVCIADGSKLVPTMGAFPLPVEVIPMARAAVARSLAALGGQPRL
RMTKEGGIYKTDNGNVILDVSGLKIENPKALEQQINQLPGVVTVGLFALRGANVLLLGTEQGVQRSDY
>Mature_227_residues
TQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKERFSGAVSSSEASTRRLQQHGFNVLDLNEVDSIP
VYVDGADEIDNSGAMIKGGGGALTREKIVASVADRFVCIADGSKLVPTMGAFPLPVEVIPMARAAVARSLAALGGQPRLR
MTKEGGIYKTDNGNVILDVSGLKIENPKALEQQINQLPGVVTVGLFALRGANVLLLGTEQGVQRSDY

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=230, Percent_Identity=36.9565217391304, Blast_Score=117, Evalue=8e-27,
Organism=Escherichia coli, GI1789280, Length=224, Percent_Identity=61.6071428571429, Blast_Score=259, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17551758, Length=206, Percent_Identity=36.8932038834951, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=198, Percent_Identity=29.7979797979798, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI281364072, Length=206, Percent_Identity=36.4077669902913, Blast_Score=103, Evalue=9e-23,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23855; Mature: 23723

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKERFSGAVSSSEAS
CCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
TRRLQQHGFNVLDLNEVDSIPVYVDGADEIDNSGAMIKGGGGALTREKIVASVADRFVCI
HHHHHHCCCCEEECCCCCCCCEEECCHHHCCCCCCEEECCCCCHHHHHHHHHHHHCEEEE
ADGSKLVPTMGAFPLPVEVIPMARAAVARSLAALGGQPRLRMTKEGGIYKTDNGNVILDV
ECCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCEEEEE
SGLKIENPKALEQQINQLPGVVTVGLFALRGANVLLLGTEQGVQRSDY
CCCEECCCHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKERFSGAVSSSEAS
CHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
TRRLQQHGFNVLDLNEVDSIPVYVDGADEIDNSGAMIKGGGGALTREKIVASVADRFVCI
HHHHHHCCCCEEECCCCCCCCEEECCHHHCCCCCCEEECCCCCHHHHHHHHHHHHCEEEE
ADGSKLVPTMGAFPLPVEVIPMARAAVARSLAALGGQPRLRMTKEGGIYKTDNGNVILDV
ECCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCEEEEE
SGLKIENPKALEQQINQLPGVVTVGLFALRGANVLLLGTEQGVQRSDY
CCCEECCCHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA