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The map label for this gene is yncB [C]

Identifier: 94310847

GI number: 94310847

Start: 2078339

End: 2079328

Strand: Reverse

Name: yncB [C]

Synonym: Rmet_1909

Alternate gene names: 94310847

Gene position: 2079328-2078339 (Counterclockwise)

Preceding gene: 94310848

Following gene: 94310846

Centisome position: 52.93

GC content: 65.76

Gene sequence:

>990_bases
ATGCCAATCATCATGAACACTATCCAGGTCAAACGAAAAGCCGCGAACATCGACGAACTCGATCTCACCCTGTTGGGGGT
GCCACGCCCCGAGGCTGCCGATGGCGAATGCGTGATCGAAGTGACCAGCGCCGGGGTGAACCCGAGCGACGTGAAGGCGA
CGCTCGGCCTGATGCCCCACGCGGTCTGGCCGCGTACCCCGGGGCGAGACTACGCAGGCGTCGTCATAGATGGGCCGGCT
GCGCTCATGGGCCAGCAGGTATGGGGCAGCGGCGGCGAGCTTGGTATCCGCCGCGACGGCACCCATGGCAAGTACCTGCG
CGTCAACGCGCAATCGGTGCGCGCCAAGCCGGCTACGCTGTCGCTGCTGGAAGCGGGTGCGGTGGGTGTGCCGTTCATCA
CCGCGTACGAAGGCTTGCGACGCGCGGGCATGCCGAAGGCAGGCAGCGTGGTGCTGGTCGGCGGTGGAAACGGCAAGGTG
GGGCAGGCCACGATCCAGATCGCCACGGCGCTCGGCGCGCGTGTCTTCGCCGTCGAGCGTGGCGCCGAGCCGTATCGCGG
CCACGCAAGCGGTCCGGTGCGCATGATCGACGCCAGCCGTGAAGGCATTGCCGACGTGGTGCGGGCCGAGACCGGCGGCC
ATGGTGCGGACATCGTCTACAACACCGTGGGCAGCCCGTACTTCGAACAAGCGAATCTGGCCATGGCGATTGGTGCCACG
CAGATCTTCATCTCGACGATCGAGAAGCCTGTACCGTTCGACATCTTCGCGTTCTATCGCGGCCAACACACGTATGTCGG
CGTCGATACGCTCGCACTGGACAGCCAGGCGTGCGCCAACATCCTGGATGCGCTCGCCCCGATGTTCGCCTCCGGTGCGT
TGAAGCCATTCCCGGTACTCGACGACTACACGTATGCACTTGCGGATGCCCGGGAGGCGTATCGCGCGGTACTGCAGGGC
GCGAGCGAGCGCGTGGTGCTCAAGCCATGA

Upstream 100 bases:

>100_bases
GGCGCGCGACATCGTGAAGTCGCTCGGTGGCGACATCGCTTCATCCGCCGATGCGCGCCGCACGCTCGGACTGCGCGAAG
TCTGATTCCTTCTCTACTGC

Downstream 100 bases:

>100_bases
ACACCACCCGGTTCGCACAGGCGCCGGCCTATTTCCCAGCCAATCACGAAGGTATGCACTGCCTGCGCTTGCAGGGGCAC
GAAGCTGGGCCGTCCGAGGC

Product: Zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPIIMNTIQVKRKAANIDELDLTLLGVPRPEAADGECVIEVTSAGVNPSDVKATLGLMPHAVWPRTPGRDYAGVVIDGPA
ALMGQQVWGSGGELGIRRDGTHGKYLRVNAQSVRAKPATLSLLEAGAVGVPFITAYEGLRRAGMPKAGSVVLVGGGNGKV
GQATIQIATALGARVFAVERGAEPYRGHASGPVRMIDASREGIADVVRAETGGHGADIVYNTVGSPYFEQANLAMAIGAT
QIFISTIEKPVPFDIFAFYRGQHTYVGVDTLALDSQACANILDALAPMFASGALKPFPVLDDYTYALADAREAYRAVLQG
ASERVVLKP

Sequences:

>Translated_329_residues
MPIIMNTIQVKRKAANIDELDLTLLGVPRPEAADGECVIEVTSAGVNPSDVKATLGLMPHAVWPRTPGRDYAGVVIDGPA
ALMGQQVWGSGGELGIRRDGTHGKYLRVNAQSVRAKPATLSLLEAGAVGVPFITAYEGLRRAGMPKAGSVVLVGGGNGKV
GQATIQIATALGARVFAVERGAEPYRGHASGPVRMIDASREGIADVVRAETGGHGADIVYNTVGSPYFEQANLAMAIGAT
QIFISTIEKPVPFDIFAFYRGQHTYVGVDTLALDSQACANILDALAPMFASGALKPFPVLDDYTYALADAREAYRAVLQG
ASERVVLKP
>Mature_328_residues
PIIMNTIQVKRKAANIDELDLTLLGVPRPEAADGECVIEVTSAGVNPSDVKATLGLMPHAVWPRTPGRDYAGVVIDGPAA
LMGQQVWGSGGELGIRRDGTHGKYLRVNAQSVRAKPATLSLLEAGAVGVPFITAYEGLRRAGMPKAGSVVLVGGGNGKVG
QATIQIATALGARVFAVERGAEPYRGHASGPVRMIDASREGIADVVRAETGGHGADIVYNTVGSPYFEQANLAMAIGATQ
IFISTIEKPVPFDIFAFYRGQHTYVGVDTLALDSQACANILDALAPMFASGALKPFPVLDDYTYALADAREAYRAVLQGA
SERVVLKP

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA, NADH and crotonyl-CoA [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=306, Percent_Identity=26.1437908496732, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI13236495, Length=306, Percent_Identity=26.1437908496732, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI194239676, Length=157, Percent_Identity=32.484076433121, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 34526; Mature: 34395

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIIMNTIQVKRKAANIDELDLTLLGVPRPEAADGECVIEVTSAGVNPSDVKATLGLMPH
CCEEECHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCC
AVWPRTPGRDYAGVVIDGPAALMGQQVWGSGGELGIRRDGTHGKYLRVNAQSVRAKPATL
CCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEHHHHCCCCCEE
SLLEAGAVGVPFITAYEGLRRAGMPKAGSVVLVGGGNGKVGQATIQIATALGARVFAVER
EHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHEEEEEHHHCCEEEEEEC
GAEPYRGHASGPVRMIDASREGIADVVRAETGGHGADIVYNTVGSPYFEQANLAMAIGAT
CCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHCCCEEEEECHH
QIFISTIEKPVPFDIFAFYRGQHTYVGVDTLALDSQACANILDALAPMFASGALKPFPVL
HHHHHHHCCCCCEEEEEEECCCEEEEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCC
DDYTYALADAREAYRAVLQGASERVVLKP
CCHHHHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure 
PIIMNTIQVKRKAANIDELDLTLLGVPRPEAADGECVIEVTSAGVNPSDVKATLGLMPH
CEEECHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCC
AVWPRTPGRDYAGVVIDGPAALMGQQVWGSGGELGIRRDGTHGKYLRVNAQSVRAKPATL
CCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEHHHHCCCCCEE
SLLEAGAVGVPFITAYEGLRRAGMPKAGSVVLVGGGNGKVGQATIQIATALGARVFAVER
EHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHEEEEEHHHCCEEEEEEC
GAEPYRGHASGPVRMIDASREGIADVVRAETGGHGADIVYNTVGSPYFEQANLAMAIGAT
CCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHCCCEEEEECHH
QIFISTIEKPVPFDIFAFYRGQHTYVGVDTLALDSQACANILDALAPMFASGALKPFPVL
HHHHHHHCCCCCEEEEEEECCCEEEEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCC
DDYTYALADAREAYRAVLQGASERVVLKP
CCHHHHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]