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The map label for this gene is clpX [H]

Identifier: 94310822

GI number: 94310822

Start: 2049502

End: 2050779

Strand: Reverse

Name: clpX [H]

Synonym: Rmet_1884

Alternate gene names: 94310822

Gene position: 2050779-2049502 (Counterclockwise)

Preceding gene: 94310823

Following gene: 94310821

Centisome position: 52.21

GC content: 59.86

Gene sequence:

>1278_bases
ATGGCGGACAAAAAAGGTTCATCCAGCGAGAAGCTTCTCTATTGCTCCTTCTGCGGCAAGAGCCAGCATGAGGTGAAGAA
GCTGATCGCCGGCCCGTCGGTGTTCATTTGCGACGAATGCATCGACCTGTGCAACGAGATCATCCGTGACGAGGCCTCCG
CGACCGACAAGGACGCCACGGCCGCCACGCGATCGGATCTGCCCACGCCCCACGAGATTCGCGAGAGCCTTGACCAGTAC
GTGATCGGGCAGGATCAGGCCAAGAAAATTCTGGCCGTAGCGGTCTACAACCACTACAAGCGCCTCAAGCACCTCGGCAA
GAAGGACGATGTCGAGCTTTCCAAGAGCAATATTCTGCTGATCGGGCCGACTGGCTCCGGCAAGACGTTGCTTGCCCAGA
CGCTGGCCCGCCTGCTCAACGTGCCGTTCGTGATCGCGGACGCGACGACGCTGACGGAAGCCGGCTACGTGGGCGAGGAT
GTCGAGAACATCATCCAGAAGCTGCTCCAGAACTGCAATTACGAGGTGGAGAAGGCGCAGCGCGGTATCGTCTACATCGA
CGAAATCGACAAGATCTCGCGCAAGTCGGACAACCCGTCGATCACCCGCGACGTTTCCGGCGAGGGTGTGCAGCAAGCGC
TGCTGAAACTGATCGAGGGCACGATGGCCTCGGTGCCGCCGCAAGGTGGCCGGAAGCATCCGAATCAGGACTTCTTGCAG
GTGGATACCACCAATATCCTGTTCATCTGCGGCGGCGCGTTTGACGGCCTGGAGAAGGTCATCATGCAGCGCTCGGACAA
GACCGGTATCGGTTTTGCCGCCCAGGTGCAGAGCAAGGAAGAGCGGGAAGTCAGCGAAGTGCTGCCACAGACCGAGCCCG
AGGATTTGATCAAGTTCGGCCTGATTCCGGAGCTGATCGGTCGTCTGCCGGTGGTGGCTACGCTAGCGAAGCTGGATGAG
GCTGCACTGATGCAGATTCTGATCGAGCCGAAGAACGCGCTGGTCAAGCAATATCAGAAGCTGCTGGCCATGGAAGGCGT
GGAGCTGGAAATCCGCCCGGCCGCACTGTCCGCGATCGCTCGCAAGGCCATTCGCCGCAAGACCGGTGCGCGCGGCCTGC
GTTCGATCCTTGAACAATCGCTGATGGATGTCATGTATGACCTGCCCAACTACAAGGGCGTCCAGAAGGTCGTGATCGAC
GAGAACACGATTACCGGCGACGCAGCGCCGCTCCTGGTTTATGAGGAGCAGCAGCCCAAGGTGGCGGGGTCTAACTGA

Upstream 100 bases:

>100_bases
CCGCCGACTGTGCCAATTGTTTTGGCGTATGATGCGTTTAATGCGTTTCCCGCCCGGTCTCCCGCCAGGTGGGAACACAC
TGCTAATGTGACTGATTCCT

Downstream 100 bases:

>100_bases
CGATCGCGCCGCACATGGGTGGCCTCGACCACACCGGCAAATTTCAAGCGGCCGTTCGCAGCAAAGCGAACGGCTTTTTT
TCTTCAATTCCACAAACGAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MADKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEASATDKDATAATRSDLPTPHEIRESLDQY
VIGQDQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGED
VENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFGLIPELIGRLPVVATLAKLDE
AALMQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIARKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVID
ENTITGDAAPLLVYEEQQPKVAGSN

Sequences:

>Translated_425_residues
MADKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEASATDKDATAATRSDLPTPHEIRESLDQY
VIGQDQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGED
VENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFGLIPELIGRLPVVATLAKLDE
AALMQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIARKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVID
ENTITGDAAPLLVYEEQQPKVAGSN
>Mature_424_residues
ADKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEASATDKDATAATRSDLPTPHEIRESLDQYV
IGQDQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQV
DTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFGLIPELIGRLPVVATLAKLDEA
ALMQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIARKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVIDE
NTITGDAAPLLVYEEQQPKVAGSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=326, Percent_Identity=50.920245398773, Blast_Score=311, Evalue=7e-85,
Organism=Escherichia coli, GI1786642, Length=416, Percent_Identity=73.3173076923077, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=48, Blast_Score=101, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71988663, Length=389, Percent_Identity=42.159383033419, Blast_Score=278, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI71982908, Length=314, Percent_Identity=44.5859872611465, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=314, Percent_Identity=44.5859872611465, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=44.1767068273092, Blast_Score=190, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6319704, Length=439, Percent_Identity=40.0911161731207, Blast_Score=280, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=46.5408805031447, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=46.5408805031447, Blast_Score=287, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46627; Mature: 46496

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEASATDKDAT
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCHHH
AATRSDLPTPHEIRESLDQYVIGQDQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILL
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
IGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFG
EECCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHC
LIPELIGRLPVVATLAKLDEAALMQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIA
CHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
RKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVIDENTITGDAAPLLVYEEQQPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCC
VAGSN
CCCCC
>Mature Secondary Structure 
ADKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEASATDKDAT
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCHHH
AATRSDLPTPHEIRESLDQYVIGQDQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILL
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
IGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFG
EECCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHC
LIPELIGRLPVVATLAKLDEAALMQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIA
CHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
RKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVIDENTITGDAAPLLVYEEQQPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCC
VAGSN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA