Click here to switch to the map view.

The map label for this gene is kipR [H]

Identifier: 94310755

GI number: 94310755

Start: 1971205

End: 1971987

Strand: Direct

Name: kipR [H]

Synonym: Rmet_1817

Alternate gene names: 94310755

Gene position: 1971205-1971987 (Clockwise)

Preceding gene: 94310748

Following gene: 94310756

Centisome position: 50.18

GC content: 68.71

Gene sequence:

>783_bases
ATGCCAACGCGCCCCCATCACCCCGATCCCGCCTTTGCCACCACGCTGGCCCACGGCCTGGCGTTGCTGCAGTGCTTTCG
CGTGGGCGAGACCGTGCTCGGCAATAAGGAACTGGCCGATCGCACCGGTCTGTCGAAAGCGACCATCAGCCGGCTGACCT
ACACGCTGGCGGCGCGCGGATTGCTGCTCTACGACACCCATTTGCGCCGCTACCGGCTGGGCTCGACCGCGCTCTCGCTT
GGGTATCCACTGCTGGCCAGCCTGCGCGTGCGGCAGCTGGCCCGGCCGCTCATGAAAGCGCTGGCCGATCAGGTTGGCGG
CTCCGTATCGCTGGGGCTGCGCGACCGGCTGCGCATGGTCTACGTCGAAACCAGCCGGGGTCACGACGCGATCGCATTTC
GTCCGGACATCGGCGCATCCCTGCCGATGCTGGCCACGGCGATGGGCCGGGCATGGCTGGCATGGGCACCGGAAGACGTG
CGCCACCGCCTGCTCGACGCGCTGCGAGAGGCCGAGCCGGACGACTACGAACGGCTGGCGGGTGCCGTGGATACGGCCAT
CGAGGAGTTGGCGACACTCGGCTTTACGCGGTCACGTGGCGACTGGCAGCGCGACGTTCACGCCGTGGCCGTGCCGATGC
GGACTCCCATCGACGGCGAGATCCTGGTCTTCAACTGCGGCGTGCCCGCGGTGCGCATGACGCCCCGGAAGCTCGAACGC
GAGATGGGGCCGCGCCTGCTGAAGCTGGTGGCGCAGGTGGAAACACTGGTGGCCTGGGAGTGA

Upstream 100 bases:

>100_bases
CGCGCCTCCCGAATGTCGGCACCGTTGTTTCGCTATCTTGAACAACCATTGCGCAATCGGCACATCGCTTCGGTAAGATG
AACGCCAAACCAAACGCCAG

Downstream 100 bases:

>100_bases
CGATGAGCGCCACCGACATCCCTCCGGACGACGCCCGCGACCGCCAGTTCGCCACCACGCTGGCCAACGGACTGGACATC
CTGCTGGCCTATCGGGCAGG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MPTRPHHPDPAFATTLAHGLALLQCFRVGETVLGNKELADRTGLSKATISRLTYTLAARGLLLYDTHLRRYRLGSTALSL
GYPLLASLRVRQLARPLMKALADQVGGSVSLGLRDRLRMVYVETSRGHDAIAFRPDIGASLPMLATAMGRAWLAWAPEDV
RHRLLDALREAEPDDYERLAGAVDTAIEELATLGFTRSRGDWQRDVHAVAVPMRTPIDGEILVFNCGVPAVRMTPRKLER
EMGPRLLKLVAQVETLVAWE

Sequences:

>Translated_260_residues
MPTRPHHPDPAFATTLAHGLALLQCFRVGETVLGNKELADRTGLSKATISRLTYTLAARGLLLYDTHLRRYRLGSTALSL
GYPLLASLRVRQLARPLMKALADQVGGSVSLGLRDRLRMVYVETSRGHDAIAFRPDIGASLPMLATAMGRAWLAWAPEDV
RHRLLDALREAEPDDYERLAGAVDTAIEELATLGFTRSRGDWQRDVHAVAVPMRTPIDGEILVFNCGVPAVRMTPRKLER
EMGPRLLKLVAQVETLVAWE
>Mature_259_residues
PTRPHHPDPAFATTLAHGLALLQCFRVGETVLGNKELADRTGLSKATISRLTYTLAARGLLLYDTHLRRYRLGSTALSLG
YPLLASLRVRQLARPLMKALADQVGGSVSLGLRDRLRMVYVETSRGHDAIAFRPDIGASLPMLATAMGRAWLAWAPEDVR
HRLLDALREAEPDDYERLAGAVDTAIEELATLGFTRSRGDWQRDVHAVAVPMRTPIDGEILVFNCGVPAVRMTPRKLERE
MGPRLLKLVAQVETLVAWE

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693096, Length=222, Percent_Identity=27.027027027027, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28763; Mature: 28632

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRPHHPDPAFATTLAHGLALLQCFRVGETVLGNKELADRTGLSKATISRLTYTLAARG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCC
LLLYDTHLRRYRLGSTALSLGYPLLASLRVRQLARPLMKALADQVGGSVSLGLRDRLRMV
HHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHCEEEE
YVETSRGHDAIAFRPDIGASLPMLATAMGRAWLAWAPEDVRHRLLDALREAEPDDYERLA
EEECCCCCCEEEECCCCCCCHHHHHHHHCCHHEEECCHHHHHHHHHHHHHCCCCHHHHHH
GAVDTAIEELATLGFTRSRGDWQRDVHAVAVPMRTPIDGEILVFNCGVPAVRMTPRKLER
HHHHHHHHHHHHHCCCCCCCCHHHHHHHEEECCCCCCCCEEEEEECCCCCEECCHHHHHH
EMGPRLLKLVAQVETLVAWE
HHCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTRPHHPDPAFATTLAHGLALLQCFRVGETVLGNKELADRTGLSKATISRLTYTLAARG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCC
LLLYDTHLRRYRLGSTALSLGYPLLASLRVRQLARPLMKALADQVGGSVSLGLRDRLRMV
HHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHCEEEE
YVETSRGHDAIAFRPDIGASLPMLATAMGRAWLAWAPEDVRHRLLDALREAEPDDYERLA
EEECCCCCCEEEECCCCCCCHHHHHHHHCCHHEEECCHHHHHHHHHHHHHCCCCHHHHHH
GAVDTAIEELATLGFTRSRGDWQRDVHAVAVPMRTPIDGEILVFNCGVPAVRMTPRKLER
HHHHHHHHHHHHHCCCCCCCCHHHHHHHEEECCCCCCCCEEEEEECCCCCEECCHHHHHH
EMGPRLLKLVAQVETLVAWE
HHCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]