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The map label for this gene is lldR [H]

Identifier: 94310727

GI number: 94310727

Start: 1940721

End: 1941419

Strand: Direct

Name: lldR [H]

Synonym: Rmet_1789

Alternate gene names: 94310727

Gene position: 1940721-1941419 (Clockwise)

Preceding gene: 94310726

Following gene: 94310728

Centisome position: 49.41

GC content: 67.24

Gene sequence:

>699_bases
ATGCAGACCCGACCCATCACCCTGACCGAGCGCGTCATCCAGCAGTTGCGTGGCGAGATTGCCGACGGCACGTTTCCCGT
GGGCGCCCGGCTTCCGACCGGCAAGCAACTGGCCGAGCGCTACGGTGTCAGCGCTGCCGTGATCCGCGAGGTGACCGAGC
ATCTGCGGTCGCTTGGGATGGTCGAAAGCCGCCAGGGTCTGGGCAGCACTGTGCGTTCCCGCGTCAGTGACAGCGGTTTC
CGTCTGAGCGGCGGCGCCGATAACACCGATCTGGCCGATATTTTCGAGCTGCGCCTTGATCTGGAAAGTGCCGCTGCCGC
GATGGCCGCGTTGCACCGGACGGAGCAGGACATTGCCCGCATGGGCGCTCTGCTCGACGCACTGGCGGCCCAGCTTGATG
ATGCCGATCACGGCGTGGAACCCGATATCCAGTTCCATATCGCCATCGCCACGGCCACGCACAACAAGTACTACCTGCAG
CTACTGCAGTACATGACGCTGCAATTGCATCAGGCGGTGCGCACCGCGCGCCTGAATTCCAGCCGGCAGCCGGGCCTGCC
CGAGCAGGTCCATGCCGAGCACGTGGCGATCTTCGATGCGATCCGCGCCCGCGATGCCGCGCAGGCCCGCCTGCACGCCG
CCGCGCACCTGCGCAACGCCGCCGCCCGGCTTGGCCTGCCCATGCGCCAGCCCCGCTGA

Upstream 100 bases:

>100_bases
AAGTAGGGTTGGGACAGATGGCCCAGCCCGCTCGACACCCGAGTTATTAAGTATTTACCCTAGGTTTTCATATAACCAGA
AAAGGGTAAGGTGTCGTCCC

Downstream 100 bases:

>100_bases
CGATTTCGCCCGATGCCCGCTTAACTTCTACTTATCTCCGCCTTTTCCCGACCGCAGATCATGTCCGATACGAACTTCGC
GCAACGCCTGACCGAAACCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MQTRPITLTERVIQQLRGEIADGTFPVGARLPTGKQLAERYGVSAAVIREVTEHLRSLGMVESRQGLGSTVRSRVSDSGF
RLSGGADNTDLADIFELRLDLESAAAAMAALHRTEQDIARMGALLDALAAQLDDADHGVEPDIQFHIAIATATHNKYYLQ
LLQYMTLQLHQAVRTARLNSSRQPGLPEQVHAEHVAIFDAIRARDAAQARLHAAAHLRNAAARLGLPMRQPR

Sequences:

>Translated_232_residues
MQTRPITLTERVIQQLRGEIADGTFPVGARLPTGKQLAERYGVSAAVIREVTEHLRSLGMVESRQGLGSTVRSRVSDSGF
RLSGGADNTDLADIFELRLDLESAAAAMAALHRTEQDIARMGALLDALAAQLDDADHGVEPDIQFHIAIATATHNKYYLQ
LLQYMTLQLHQAVRTARLNSSRQPGLPEQVHAEHVAIFDAIRARDAAQARLHAAAHLRNAAARLGLPMRQPR
>Mature_232_residues
MQTRPITLTERVIQQLRGEIADGTFPVGARLPTGKQLAERYGVSAAVIREVTEHLRSLGMVESRQGLGSTVRSRVSDSGF
RLSGGADNTDLADIFELRLDLESAAAAMAALHRTEQDIARMGALLDALAAQLDDADHGVEPDIQFHIAIATATHNKYYLQ
LLQYMTLQLHQAVRTARLNSSRQPGLPEQVHAEHVAIFDAIRARDAAQARLHAAAHLRNAAARLGLPMRQPR

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=220, Percent_Identity=32.2727272727273, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1786303, Length=223, Percent_Identity=34.5291479820628, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790780, Length=233, Percent_Identity=32.618025751073, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789353, Length=230, Percent_Identity=29.5652173913043, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87082208, Length=227, Percent_Identity=29.0748898678414, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994955, Length=225, Percent_Identity=28.8888888888889, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25375; Mature: 25375

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTRPITLTERVIQQLRGEIADGTFPVGARLPTGKQLAERYGVSAAVIREVTEHLRSLGM
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCC
VESRQGLGSTVRSRVSDSGFRLSGGADNTDLADIFELRLDLESAAAAMAALHRTEQDIAR
HHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGALLDALAAQLDDADHGVEPDIQFHIAIATATHNKYYLQLLQYMTLQLHQAVRTARLNS
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
SRQPGLPEQVHAEHVAIFDAIRARDAAQARLHAAAHLRNAAARLGLPMRQPR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQTRPITLTERVIQQLRGEIADGTFPVGARLPTGKQLAERYGVSAAVIREVTEHLRSLGM
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCC
VESRQGLGSTVRSRVSDSGFRLSGGADNTDLADIFELRLDLESAAAAMAALHRTEQDIAR
HHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGALLDALAAQLDDADHGVEPDIQFHIAIATATHNKYYLQLLQYMTLQLHQAVRTARLNS
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
SRQPGLPEQVHAEHVAIFDAIRARDAAQARLHAAAHLRNAAARLGLPMRQPR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]