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The map label for this gene is glcD [C]

Identifier: 94310728

GI number: 94310728

Start: 1941480

End: 1942892

Strand: Direct

Name: glcD [C]

Synonym: Rmet_1790

Alternate gene names: 94310728

Gene position: 1941480-1942892 (Clockwise)

Preceding gene: 94310727

Following gene: 94310729

Centisome position: 49.43

GC content: 66.03

Gene sequence:

>1413_bases
ATGTCCGATACGAACTTCGCGCAACGCCTGACCGAAACCCTGGGCCCCGACGTCGTGACCACCGCACCCGACGACGTGGC
ACCCTGGCTCTCCGACTGGCGTGGCCTCTACAAGGGCCAGGCGCAGGCGGTAATCCGTCCGCGCACAACCGAACAGGTGG
CGCAGGCGCTGGCGCTGTGCCAGCAGGCTGGTGTGCCCGTGGTGCCGCGCGGTGGCAATACCGGCCTGTGTGGCGGCGCC
GCTCCGGACGGCAACCAGACCAACGTCGTGCTCAGCCTCGATCGCATGGACAAGATCCGCTCGATCGACACGATCGCCAA
CACAATGGTGGTCGAGGCTGGCTGCATTCTCGGCAACCTGCGCCGTGCCGCCGAGGACGCCGACCGCCTGTTCCCGCTGT
CGCTGGCCGCCGAGGACTCCTGCCAGATCGGTGGCAACCTGGCCACCAACGCCGGCGGCGTCAACGTGGTGCGCTATGGC
ATGACGCGCGAACTGGTGCTCGGCGTTGAAGCCGTGCTGCCGAACGGCGAGATCTTTCACGGCCTGCGCACGCTGCGCAA
GGACAACACCGGATACGACCTCAAGCAGTTGCTGATCGGCTCGGAAGGCACGCTCGGCATCATCACCGCCGCCGCGCTGC
GCCTGCTGCCGCGCGCCGATTCCCGCGCCGTGGTGCTGGCCGCGGTGGAATCGCCCAAGCAAGCGCTGGAACTGTTCTCG
CTGCTGTTCGCGCGCTGCGGCGCACGGTTGCAGGCCTATGAGTTCTTTACCGGCGCCTGCCTGGATCTGGTGCTGACCCA
TGTCGAGGGCATTCATGCCCCGTTTGCAGAACGTTATCCGGCCTACGTGCTGGTCGAGATCGCGGACACAGCGCCCGAGG
ATGTGCTCAACGCCCTGCTCGAATCGGTCATCGGCGATGCGCTCGAACAGGGCCTGTGCCTGGATGCCGCCGTCTCGGCC
TCACTGGCGCAGTTGCAGAGCCTGTGGCGTCTGCGCGAGGAAATCTCCGAGGCCCAGCGTGCCGACGGGCTGCACCTGAA
GCACGACGTATCCCTGCCGATCGAAGCCATTCCGGACTTCATGACCTCGATGGAAACCCGTCTGGCCGCGCGTCACCCGG
GCGTCCGCCCCTTTATCTTCGGCCACTTCGGCGATGGCAACCTGCACTACAACCTGTCCCGTCCGCTTGGCGCCGATCCG
AAATGGGCGCTCAATGAAGGCAAGGCCGTCAGCGAGGACGTGCTGGAAGAGGTGGCCCGCTACGACGGCAGCATCAGCGC
CGAGCACGGCATCGGCCAGCTCAAGCGGGAGTCGTTCCTGGCGCTCAAGGACCCGCTCGAATTGCGCCTGATGCGAGCCA
TCAAGCAGGTATTCGATCCGAGCGGGATCATGAATCCGGGCAAGCTGCTCTAA

Upstream 100 bases:

>100_bases
CGCCGCCCGGCTTGGCCTGCCCATGCGCCAGCCCCGCTGACGATTTCGCCCGATGCCCGCTTAACTTCTACTTATCTCCG
CCTTTTCCCGACCGCAGATC

Downstream 100 bases:

>100_bases
ATTTGGGCCAGTCATCGGCCATTTTGCGACCCTTGTAACGGGCCGCCTGCCGGCCACCGCCACTCGCTATACTGGGGGCC
TTTCTCGGCATTCGTCCGTT

Product: glycolate oxidase subunit glcD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSDTNFAQRLTETLGPDVVTTAPDDVAPWLSDWRGLYKGQAQAVIRPRTTEQVAQALALCQQAGVPVVPRGGNTGLCGGA
APDGNQTNVVLSLDRMDKIRSIDTIANTMVVEAGCILGNLRRAAEDADRLFPLSLAAEDSCQIGGNLATNAGGVNVVRYG
MTRELVLGVEAVLPNGEIFHGLRTLRKDNTGYDLKQLLIGSEGTLGIITAAALRLLPRADSRAVVLAAVESPKQALELFS
LLFARCGARLQAYEFFTGACLDLVLTHVEGIHAPFAERYPAYVLVEIADTAPEDVLNALLESVIGDALEQGLCLDAAVSA
SLAQLQSLWRLREEISEAQRADGLHLKHDVSLPIEAIPDFMTSMETRLAARHPGVRPFIFGHFGDGNLHYNLSRPLGADP
KWALNEGKAVSEDVLEEVARYDGSISAEHGIGQLKRESFLALKDPLELRLMRAIKQVFDPSGIMNPGKLL

Sequences:

>Translated_470_residues
MSDTNFAQRLTETLGPDVVTTAPDDVAPWLSDWRGLYKGQAQAVIRPRTTEQVAQALALCQQAGVPVVPRGGNTGLCGGA
APDGNQTNVVLSLDRMDKIRSIDTIANTMVVEAGCILGNLRRAAEDADRLFPLSLAAEDSCQIGGNLATNAGGVNVVRYG
MTRELVLGVEAVLPNGEIFHGLRTLRKDNTGYDLKQLLIGSEGTLGIITAAALRLLPRADSRAVVLAAVESPKQALELFS
LLFARCGARLQAYEFFTGACLDLVLTHVEGIHAPFAERYPAYVLVEIADTAPEDVLNALLESVIGDALEQGLCLDAAVSA
SLAQLQSLWRLREEISEAQRADGLHLKHDVSLPIEAIPDFMTSMETRLAARHPGVRPFIFGHFGDGNLHYNLSRPLGADP
KWALNEGKAVSEDVLEEVARYDGSISAEHGIGQLKRESFLALKDPLELRLMRAIKQVFDPSGIMNPGKLL
>Mature_469_residues
SDTNFAQRLTETLGPDVVTTAPDDVAPWLSDWRGLYKGQAQAVIRPRTTEQVAQALALCQQAGVPVVPRGGNTGLCGGAA
PDGNQTNVVLSLDRMDKIRSIDTIANTMVVEAGCILGNLRRAAEDADRLFPLSLAAEDSCQIGGNLATNAGGVNVVRYGM
TRELVLGVEAVLPNGEIFHGLRTLRKDNTGYDLKQLLIGSEGTLGIITAAALRLLPRADSRAVVLAAVESPKQALELFSL
LFARCGARLQAYEFFTGACLDLVLTHVEGIHAPFAERYPAYVLVEIADTAPEDVLNALLESVIGDALEQGLCLDAAVSAS
LAQLQSLWRLREEISEAQRADGLHLKHDVSLPIEAIPDFMTSMETRLAARHPGVRPFIFGHFGDGNLHYNLSRPLGADPK
WALNEGKAVSEDVLEEVARYDGSISAEHGIGQLKRESFLALKDPLELRLMRAIKQVFDPSGIMNPGKLL

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=465, Percent_Identity=39.5698924731183, Blast_Score=302, Evalue=5e-82,
Organism=Homo sapiens, GI37595756, Length=436, Percent_Identity=31.651376146789, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI37595754, Length=459, Percent_Identity=30.0653594771242, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI4501993, Length=185, Percent_Identity=28.1081081081081, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1789351, Length=450, Percent_Identity=29.5555555555556, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1787977, Length=550, Percent_Identity=25.4545454545455, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI48994907, Length=449, Percent_Identity=22.271714922049, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534361, Length=459, Percent_Identity=35.0762527233115, Blast_Score=270, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI71992373, Length=438, Percent_Identity=28.5388127853881, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71992381, Length=438, Percent_Identity=27.6255707762557, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71992392, Length=359, Percent_Identity=28.6908077994429, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17556096, Length=176, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320023, Length=457, Percent_Identity=36.5426695842451, Blast_Score=313, Evalue=4e-86,
Organism=Saccharomyces cerevisiae, GI6320764, Length=466, Percent_Identity=33.0472103004292, Blast_Score=279, Evalue=9e-76,
Organism=Saccharomyces cerevisiae, GI6320027, Length=438, Percent_Identity=27.6255707762557, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI18921117, Length=478, Percent_Identity=36.1924686192469, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24639277, Length=478, Percent_Identity=36.1924686192469, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24639275, Length=478, Percent_Identity=36.1924686192469, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24653753, Length=189, Percent_Identity=27.5132275132275, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 50627; Mature: 50496

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTNFAQRLTETLGPDVVTTAPDDVAPWLSDWRGLYKGQAQAVIRPRTTEQVAQALALC
CCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
QQAGVPVVPRGGNTGLCGGAAPDGNQTNVVLSLDRMDKIRSIDTIANTMVVEAGCILGNL
HHCCCCEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAAEDADRLFPLSLAAEDSCQIGGNLATNAGGVNVVRYGMTRELVLGVEAVLPNGEIFH
HHHHHHHHHEEEEEECCCCCCCCCCCEECCCCCCEEEEECCHHHHHHHHHHHCCCCHHHH
GLRTLRKDNTGYDLKQLLIGSEGTLGIITAAALRLLPRADSRAVVLAAVESPKQALELFS
HHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHH
LLFARCGARLQAYEFFTGACLDLVLTHVEGIHAPFAERYPAYVLVEIADTAPEDVLNALL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCHHHHHHHHH
ESVIGDALEQGLCLDAAVSASLAQLQSLWRLREEISEAQRADGLHLKHDVSLPIEAIPDF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
MTSMETRLAARHPGVRPFIFGHFGDGNLHYNLSRPLGADPKWALNEGKAVSEDVLEEVAR
HHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
YDGSISAEHGIGQLKRESFLALKDPLELRLMRAIKQVFDPSGIMNPGKLL
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SDTNFAQRLTETLGPDVVTTAPDDVAPWLSDWRGLYKGQAQAVIRPRTTEQVAQALALC
CCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
QQAGVPVVPRGGNTGLCGGAAPDGNQTNVVLSLDRMDKIRSIDTIANTMVVEAGCILGNL
HHCCCCEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAAEDADRLFPLSLAAEDSCQIGGNLATNAGGVNVVRYGMTRELVLGVEAVLPNGEIFH
HHHHHHHHHEEEEEECCCCCCCCCCCEECCCCCCEEEEECCHHHHHHHHHHHCCCCHHHH
GLRTLRKDNTGYDLKQLLIGSEGTLGIITAAALRLLPRADSRAVVLAAVESPKQALELFS
HHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHH
LLFARCGARLQAYEFFTGACLDLVLTHVEGIHAPFAERYPAYVLVEIADTAPEDVLNALL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCHHHHHHHHH
ESVIGDALEQGLCLDAAVSASLAQLQSLWRLREEISEAQRADGLHLKHDVSLPIEAIPDF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
MTSMETRLAARHPGVRPFIFGHFGDGNLHYNLSRPLGADPKWALNEGKAVSEDVLEEVAR
HHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
YDGSISAEHGIGQLKRESFLALKDPLELRLMRAIKQVFDPSGIMNPGKLL
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]