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The map label for this gene is pyc [H]

Identifier: 94310580

GI number: 94310580

Start: 1767489

End: 1770992

Strand: Direct

Name: pyc [H]

Synonym: Rmet_1638

Alternate gene names: 94310580

Gene position: 1767489-1770992 (Clockwise)

Preceding gene: 335055538

Following gene: 94310588

Centisome position: 45.0

GC content: 64.98

Gene sequence:

>3504_bases
ATGGACTTCGCCCCGATCAAGTCGTTGTTGATTGCCAACCGTTCCGAGATCGCGATTCGCGTGATGCGGGCCGCCGCCGA
GATGAGCATCCGCACAGTCGCTATCTACTCGAAGGAGGACCGGCTCGCGCTTCATCGCTTCAAGGCCGATGAGAGCTATC
TGGTTGGCGACGGCAAGAAGCCGCTGGCGGCTTACCTCGATATCGAAGACGTTCTGCGGATCGCCCGGCAGGCAAAGGTC
GACGCGATTCACCCGGGGTATGGTTTTCTGTCCGAGAACCCGGACTTCGCCCAGGCGGTCATCGACGCTGGCATTCGCTG
GATCGGGCCATCGCCTGAAGTCATGCGGATGCTCGGCAACAAGGTGGCGGCGCGTAATGCGGCCATTGCGGCGGGTGTGC
CCGTCATGCCGGCGACCGATCCGCTGCCGCTCGATCTGGCCGAGTGCAAGCGCCTGGCGGCCGGCATTGGCTATCCGTTG
ATGCTCAAGGCGAGCTGGGGTGGTGGTGGCCGTGGCATGCGGGTACTGGAGAGCGAACAGGACCTGGAGCCTTCGCTGGC
GGCGGCCCGTCGCGAGGCGCTGGCCGCGTTTGGCAACGACGAGGTGTACCTGGAGAAGCTGGTGCGCAACGCGCGCCACG
TCGAGGTGCAGATCCTGGGCGACACGCACGGCAATCTCGTGCATCTGCACGAGCGTGACTGCACGGTGCAGCGGCGCAAC
CAGAAGGTTATCGAACGCGCGCCTGCGCCATACATGGATGCGGCCGGTCGCGCGTCACTGTGCGACGCGGCGCTGCGCCT
GATGGGCGCGGTCGGCTATTCGCACGCCGGCACGGTGGAATTCCTGATGGATGCGGACACGAACAAGTTCTACTTCATCG
AGGTCAATCCACGTATCCAGGTGGAACACACGGTCACCGAAATGATCACGGGGATCGACATCGTCAAGGCACAGATCCGC
GTCACGGAAGGCGGCCGGATCGGCATGACCGAAGACACGCTCGACGAGAACGGCGATATCACCACGCGCGCGGCGGGCGT
GCCGCCGCAGGCCCAGATTCCGCTCAATGGCCACGCGCTGCAATGCCGGATCACGTCCGAGGACCCTGAGAATGGCTTCC
TGCCGGACTATGGCCGTCTCACCGCGTATCGCAGCGCGGCCGGCTTCGGGGTGCGCCTGGATGCCGGCACCGCCTATGGC
GGCGCGGTGATCACGCCGTACTACGATTCGCTGCTGGTCAAGGTCACCACCTGGGCGCCGACGGCCGCCGAGTCGATCCG
CCGCATGGATCGCGCCCTGCGCGAGTTCCGCATTCGCGGGGTGTCCTCCAACCTGCAGTTCCTGGAGAACGTCATCAACC
ATCCCGCGTTTGGGAGCGGTGACGTCACCACGCGCTTTATCGACCTGACGCCGGAACTGCTGGCCTTCACCAAACGGCGT
GATACCGCCACCAAGCTGTTGAGCTATCTGGGCGACGTCAGCATCAACGGTCATCAGGAAATGACGGGCCGCGCGGTGCC
GCAGTTGCCGCTTCCGAGGCCAGTCCTGCCGGTGGTTGACACCACCAGACCGCTTCCCCTCGGCACGCGCGATCGACTGC
GTGAACTGGGCGCGGAGAAATTCGCAAGCTGGATGCTGGATCAGAAGCAGGTGCTGCTGACCGACACCACCATGCGCGAT
GCGCACCAGTCGTTGTTTGCCACACGGATGCGTACGGCAGACATGCTGCCGATCGCGCCGTTCTACGCCAGCGAGCTGTC
GCAACTGTTTTCGATGGAGTGCTGGGGCGGCGCCACGTTCGACGTGGCCTTGCGCTTCCTGAAGGAAGACCCGTGGCAGC
GCCTGGCGCAACTGCGCGAGCGCGTGCCGAACATCCTGTTCCAGATGCTGCTGCGCGGCTCGAATGCCGTCGGTTACACG
AACTACGCGGACAACGTGGTGCGTTTCTTCGTCAAGCAGGCCGCCAGTACCGGCGTGGACGTATTCCGCGTGTTCGATTC
GTTGAACTGGGTGCGCAACATGCGCGTGGCGATCGACGCCGTAGGCGAAACCGGCGCGCTGTGCGAAGGTGCGATTTGCT
ATACGGGCGATCTGTTCGATGGCTCCCGCCCCAAGTACGACCTGAAGTACTACGTGGGCATCGCCCGCGAACTGCAACGC
GCTGGCGTGCACGTGCTCGGCATCAAGGACATGGCGGGTATCTGCCGCCCCCAGGCCGCTGCGGCGCTGGTCAAGGCGCT
GAAGGAAGAGACCGGGCTGCCCGTGCATTTCCACACACACGATACCAGCGGCATTTCAGCGGCATCGGCACTGGCTGCCA
TCGAGGCGGGCTGCGATGCCGTCGACGGCGCGCTGGACGCGATGAGCGGGCTCACGTCGCAACCGAACCTGTCGAGTATT
GTCGCCGCGCTGGCCGGCAGCGAGCGCGATCCCGGACTCAGTCTGGACCGCCTGCACGAAGCGTCGATGTATTGGGAGGG
CGTGCGCCGCTACTACGCGCCGTTCGAGTCCGAAATTCGCGCTGGTACTGCCGACGTCTATCGCCACGAGATGCCGGGTG
GCCAGTACACGAACCTGCGCGAGCAGGCTCGCTCGCTTGGCATCGAGCATCGATGGACCGAAGTGTCGCGCGCCTACGCC
GACGTCAACCGGATGTTCGGTGACATCGTGAAGGTGACGCCTACGTCGAAGGTGGTTGGCGATCTGGCGCTGATGATGGT
GGCCAACGATATGACGGCAGCGGATGTGTGCGATCCGAACAAGGAGGTGGCATTCCCCGAATCCGTGGTGTCGCTGTTCA
AGGGCGAACTGGGCTTCCCGCCGGATGGCTTCCCGGCCGAGCTTTCGCGCAAGGTGCTCCGAGGTGAGCCGCCCGCGCCG
TACCGTCCGGGCGACCTGATCCCGGCCGTCGATCTCGATGTCGTCCGCGCACAGGGTGAGGCCGCCTGCGAGCAGCCGCT
CGATGACATGCAACTGGCGTCGTACCTGATGTATCCGAAGCAGACGGTCGAGTACCACGCGCATGTGCGCGCCTATAGCG
ATACATCGGTGCTGCCGACCCCGGCCTATCTGTACGGGCTGCAGCCCCAGGAAGAAGTGGCCGTCGACATTGCGGCGGGC
AAGACACTCCTCGTCTCGCTGCAAGGCACTCACCCCGATGCCGAAGAGGGCGTGATCAAGGTCCAGTTCGAGCTGAACGG
CCAGTCGCGCACGGCCCTGATCGAGCAGCGCAGTACGGTCAGCGTGGCCACGGCCCGACAGGGCCGCCAGGTTGCGGATC
CCGAGAACCCGTTGCACATCGCCGCGCCGATGCCGGGCTCGATCGTGACCGTGGCGGTGCAGCCCGGGCAGCGTGTGGCA
GCCGGCACGACGCTGCTCGCGCTGGAGGCGATGAAGATGGAGACCCACATCGCGGCCGATCGCGACGGCGAGATCGCTGC
CGTGCACGTCAAGCCTGGCGACCGCGTGGCAGCGAAGGATCTGCTGATCGAGTTGAAGGGTTGA

Upstream 100 bases:

>100_bases
CGACTTCTCCGGCATGGGCAGGACCTGCCCACCGCCGTCTTCTGACTTCTGGCCATGGCGTGTCCCCACGCGTGGCCTGT
TCGCTTAGGTTGCATGCCCT

Downstream 100 bases:

>100_bases
AGCGTTGAAGCGTTGAAGGGGGCGGGCGTTAAAGGGAAGGGCATTCGGCCAGACGCAAAAAAGGCCCGCCAAGGCGGGCC
TGCAATGACGAAGGAAACCT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1167; Mature: 1167

Protein sequence:

>1167_residues
MDFAPIKSLLIANRSEIAIRVMRAAAEMSIRTVAIYSKEDRLALHRFKADESYLVGDGKKPLAAYLDIEDVLRIARQAKV
DAIHPGYGFLSENPDFAQAVIDAGIRWIGPSPEVMRMLGNKVAARNAAIAAGVPVMPATDPLPLDLAECKRLAAGIGYPL
MLKASWGGGGRGMRVLESEQDLEPSLAAARREALAAFGNDEVYLEKLVRNARHVEVQILGDTHGNLVHLHERDCTVQRRN
QKVIERAPAPYMDAAGRASLCDAALRLMGAVGYSHAGTVEFLMDADTNKFYFIEVNPRIQVEHTVTEMITGIDIVKAQIR
VTEGGRIGMTEDTLDENGDITTRAAGVPPQAQIPLNGHALQCRITSEDPENGFLPDYGRLTAYRSAAGFGVRLDAGTAYG
GAVITPYYDSLLVKVTTWAPTAAESIRRMDRALREFRIRGVSSNLQFLENVINHPAFGSGDVTTRFIDLTPELLAFTKRR
DTATKLLSYLGDVSINGHQEMTGRAVPQLPLPRPVLPVVDTTRPLPLGTRDRLRELGAEKFASWMLDQKQVLLTDTTMRD
AHQSLFATRMRTADMLPIAPFYASELSQLFSMECWGGATFDVALRFLKEDPWQRLAQLRERVPNILFQMLLRGSNAVGYT
NYADNVVRFFVKQAASTGVDVFRVFDSLNWVRNMRVAIDAVGETGALCEGAICYTGDLFDGSRPKYDLKYYVGIARELQR
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDAVDGALDAMSGLTSQPNLSSI
VAALAGSERDPGLSLDRLHEASMYWEGVRRYYAPFESEIRAGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYA
DVNRMFGDIVKVTPTSKVVGDLALMMVANDMTAADVCDPNKEVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
YRPGDLIPAVDLDVVRAQGEAACEQPLDDMQLASYLMYPKQTVEYHAHVRAYSDTSVLPTPAYLYGLQPQEEVAVDIAAG
KTLLVSLQGTHPDAEEGVIKVQFELNGQSRTALIEQRSTVSVATARQGRQVADPENPLHIAAPMPGSIVTVAVQPGQRVA
AGTTLLALEAMKMETHIAADRDGEIAAVHVKPGDRVAAKDLLIELKG

Sequences:

>Translated_1167_residues
MDFAPIKSLLIANRSEIAIRVMRAAAEMSIRTVAIYSKEDRLALHRFKADESYLVGDGKKPLAAYLDIEDVLRIARQAKV
DAIHPGYGFLSENPDFAQAVIDAGIRWIGPSPEVMRMLGNKVAARNAAIAAGVPVMPATDPLPLDLAECKRLAAGIGYPL
MLKASWGGGGRGMRVLESEQDLEPSLAAARREALAAFGNDEVYLEKLVRNARHVEVQILGDTHGNLVHLHERDCTVQRRN
QKVIERAPAPYMDAAGRASLCDAALRLMGAVGYSHAGTVEFLMDADTNKFYFIEVNPRIQVEHTVTEMITGIDIVKAQIR
VTEGGRIGMTEDTLDENGDITTRAAGVPPQAQIPLNGHALQCRITSEDPENGFLPDYGRLTAYRSAAGFGVRLDAGTAYG
GAVITPYYDSLLVKVTTWAPTAAESIRRMDRALREFRIRGVSSNLQFLENVINHPAFGSGDVTTRFIDLTPELLAFTKRR
DTATKLLSYLGDVSINGHQEMTGRAVPQLPLPRPVLPVVDTTRPLPLGTRDRLRELGAEKFASWMLDQKQVLLTDTTMRD
AHQSLFATRMRTADMLPIAPFYASELSQLFSMECWGGATFDVALRFLKEDPWQRLAQLRERVPNILFQMLLRGSNAVGYT
NYADNVVRFFVKQAASTGVDVFRVFDSLNWVRNMRVAIDAVGETGALCEGAICYTGDLFDGSRPKYDLKYYVGIARELQR
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDAVDGALDAMSGLTSQPNLSSI
VAALAGSERDPGLSLDRLHEASMYWEGVRRYYAPFESEIRAGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYA
DVNRMFGDIVKVTPTSKVVGDLALMMVANDMTAADVCDPNKEVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
YRPGDLIPAVDLDVVRAQGEAACEQPLDDMQLASYLMYPKQTVEYHAHVRAYSDTSVLPTPAYLYGLQPQEEVAVDIAAG
KTLLVSLQGTHPDAEEGVIKVQFELNGQSRTALIEQRSTVSVATARQGRQVADPENPLHIAAPMPGSIVTVAVQPGQRVA
AGTTLLALEAMKMETHIAADRDGEIAAVHVKPGDRVAAKDLLIELKG
>Mature_1167_residues
MDFAPIKSLLIANRSEIAIRVMRAAAEMSIRTVAIYSKEDRLALHRFKADESYLVGDGKKPLAAYLDIEDVLRIARQAKV
DAIHPGYGFLSENPDFAQAVIDAGIRWIGPSPEVMRMLGNKVAARNAAIAAGVPVMPATDPLPLDLAECKRLAAGIGYPL
MLKASWGGGGRGMRVLESEQDLEPSLAAARREALAAFGNDEVYLEKLVRNARHVEVQILGDTHGNLVHLHERDCTVQRRN
QKVIERAPAPYMDAAGRASLCDAALRLMGAVGYSHAGTVEFLMDADTNKFYFIEVNPRIQVEHTVTEMITGIDIVKAQIR
VTEGGRIGMTEDTLDENGDITTRAAGVPPQAQIPLNGHALQCRITSEDPENGFLPDYGRLTAYRSAAGFGVRLDAGTAYG
GAVITPYYDSLLVKVTTWAPTAAESIRRMDRALREFRIRGVSSNLQFLENVINHPAFGSGDVTTRFIDLTPELLAFTKRR
DTATKLLSYLGDVSINGHQEMTGRAVPQLPLPRPVLPVVDTTRPLPLGTRDRLRELGAEKFASWMLDQKQVLLTDTTMRD
AHQSLFATRMRTADMLPIAPFYASELSQLFSMECWGGATFDVALRFLKEDPWQRLAQLRERVPNILFQMLLRGSNAVGYT
NYADNVVRFFVKQAASTGVDVFRVFDSLNWVRNMRVAIDAVGETGALCEGAICYTGDLFDGSRPKYDLKYYVGIARELQR
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDAVDGALDAMSGLTSQPNLSSI
VAALAGSERDPGLSLDRLHEASMYWEGVRRYYAPFESEIRAGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYA
DVNRMFGDIVKVTPTSKVVGDLALMMVANDMTAADVCDPNKEVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
YRPGDLIPAVDLDVVRAQGEAACEQPLDDMQLASYLMYPKQTVEYHAHVRAYSDTSVLPTPAYLYGLQPQEEVAVDIAAG
KTLLVSLQGTHPDAEEGVIKVQFELNGQSRTALIEQRSTVSVATARQGRQVADPENPLHIAAPMPGSIVTVAVQPGQRVA
AGTTLLALEAMKMETHIAADRDGEIAAVHVKPGDRVAAKDLLIELKG

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1177, Percent_Identity=47.0688190314359, Blast_Score=1036, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1177, Percent_Identity=47.0688190314359, Blast_Score=1036, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1177, Percent_Identity=47.0688190314359, Blast_Score=1036, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=475, Percent_Identity=42.1052631578947, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI65506442, Length=470, Percent_Identity=40.8510638297872, Blast_Score=347, Evalue=4e-95,
Organism=Homo sapiens, GI189095269, Length=470, Percent_Identity=40.8510638297872, Blast_Score=347, Evalue=4e-95,
Organism=Homo sapiens, GI295821183, Length=470, Percent_Identity=40.8510638297872, Blast_Score=347, Evalue=6e-95,
Organism=Homo sapiens, GI134142062, Length=510, Percent_Identity=33.3333333333333, Blast_Score=239, Evalue=8e-63,
Organism=Homo sapiens, GI38679977, Length=513, Percent_Identity=31.5789473684211, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI38679967, Length=513, Percent_Identity=31.5789473684211, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI38679971, Length=513, Percent_Identity=31.5789473684211, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI38679974, Length=513, Percent_Identity=31.5789473684211, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI38679960, Length=513, Percent_Identity=31.5789473684211, Blast_Score=231, Evalue=3e-60,
Organism=Escherichia coli, GI1789654, Length=464, Percent_Identity=41.5948275862069, Blast_Score=343, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI17562816, Length=1174, Percent_Identity=47.4446337308348, Blast_Score=1051, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=475, Percent_Identity=44.421052631579, Blast_Score=371, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17567343, Length=468, Percent_Identity=41.4529914529915, Blast_Score=345, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI71997168, Length=519, Percent_Identity=29.2870905587669, Blast_Score=208, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71997163, Length=519, Percent_Identity=29.2870905587669, Blast_Score=207, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI133931226, Length=502, Percent_Identity=29.2828685258964, Blast_Score=197, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1178, Percent_Identity=44.9915110356537, Blast_Score=974, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1178, Percent_Identity=45.5857385398981, Blast_Score=965, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=461, Percent_Identity=37.527114967462, Blast_Score=318, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6324343, Length=517, Percent_Identity=32.1083172147002, Blast_Score=228, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6323863, Length=438, Percent_Identity=32.4200913242009, Blast_Score=221, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24652212, Length=1174, Percent_Identity=48.1260647359455, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1174, Percent_Identity=48.1260647359455, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1174, Percent_Identity=48.1260647359455, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1174, Percent_Identity=48.1260647359455, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1174, Percent_Identity=48.1260647359455, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1188, Percent_Identity=47.4747474747475, Blast_Score=1046, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1188, Percent_Identity=47.4747474747475, Blast_Score=1046, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1188, Percent_Identity=47.4747474747475, Blast_Score=1046, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1188, Percent_Identity=47.4747474747475, Blast_Score=1046, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1188, Percent_Identity=47.4747474747475, Blast_Score=1046, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=468, Percent_Identity=41.2393162393162, Blast_Score=346, Evalue=7e-95,
Organism=Drosophila melanogaster, GI24651759, Length=429, Percent_Identity=40.5594405594406, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI161076407, Length=501, Percent_Identity=30.3393213572854, Blast_Score=214, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24586460, Length=501, Percent_Identity=30.3393213572854, Blast_Score=214, Evalue=4e-55,
Organism=Drosophila melanogaster, GI161076409, Length=501, Percent_Identity=30.3393213572854, Blast_Score=213, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24586458, Length=501, Percent_Identity=30.3393213572854, Blast_Score=213, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 127279; Mature: 127279

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFAPIKSLLIANRSEIAIRVMRAAAEMSIRTVAIYSKEDRLALHRFKADESYLVGDGKK
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCCEEECCCCC
PLAAYLDIEDVLRIARQAKVDAIHPGYGFLSENPDFAQAVIDAGIRWIGPSPEVMRMLGN
CCEEECCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHHH
KVAARNAAIAAGVPVMPATDPLPLDLAECKRLAAGIGYPLMLKASWGGGGRGMRVLESEQ
HHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCC
DLEPSLAAARREALAAFGNDEVYLEKLVRNARHVEVQILGDTHGNLVHLHERDCTVQRRN
CCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHH
QKVIERAPAPYMDAAGRASLCDAALRLMGAVGYSHAGTVEFLMDADTNKFYFIEVNPRIQ
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCEEE
VEHTVTEMITGIDIVKAQIRVTEGGRIGMTEDTLDENGDITTRAAGVPPQAQIPLNGHAL
EHHHHHHHHHCHHEEEEEEEEECCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEE
QCRITSEDPENGFLPDYGRLTAYRSAAGFGVRLDAGTAYGGAVITPYYDSLLVKVTTWAP
EEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCEEEEEEECCC
TAAESIRRMDRALREFRIRGVSSNLQFLENVINHPAFGSGDVTTRFIDLTPELLAFTKRR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHCC
DTATKLLSYLGDVSINGHQEMTGRAVPQLPLPRPVLPVVDTTRPLPLGTRDRLRELGAEK
HHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FASWMLDQKQVLLTDTTMRDAHQSLFATRMRTADMLPIAPFYASELSQLFSMECWGGATF
HHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
DVALRFLKEDPWQRLAQLRERVPNILFQMLLRGSNAVGYTNYADNVVRFFVKQAASTGVD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
VFRVFDSLNWVRNMRVAIDAVGETGALCEGAICYTGDLFDGSRPKYDLKYYVGIARELQR
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHH
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDA
CCEEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCH
VDGALDAMSGLTSQPNLSSIVAALAGSERDPGLSLDRLHEASMYWEGVRRYYAPFESEIR
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHC
AGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYADVNRMFGDIVKVTPTSKVVG
CCHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCHHHHH
DLALMMVANDMTAADVCDPNKEVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
HHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCC
YRPGDLIPAVDLDVVRAQGEAACEQPLDDMQLASYLMYPKQTVEYHAHVRAYSDTSVLPT
CCCCCCCCCCCHHHHHCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHEEEEECCCCCCCC
PAYLYGLQPQEEVAVDIAAGKTLLVSLQGTHPDAEEGVIKVQFELNGQSRTALIEQRSTV
CHHEECCCCHHHHEEEEECCCEEEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHCCCCE
SVATARQGRQVADPENPLHIAAPMPGSIVTVAVQPGQRVAAGTTLLALEAMKMETHIAAD
EEHHHHCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
RDGEIAAVHVKPGDRVAAKDLLIELKG
CCCCEEEEEECCCCCEEHEEEEEEECC
>Mature Secondary Structure
MDFAPIKSLLIANRSEIAIRVMRAAAEMSIRTVAIYSKEDRLALHRFKADESYLVGDGKK
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCCEEECCCCC
PLAAYLDIEDVLRIARQAKVDAIHPGYGFLSENPDFAQAVIDAGIRWIGPSPEVMRMLGN
CCEEECCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHHH
KVAARNAAIAAGVPVMPATDPLPLDLAECKRLAAGIGYPLMLKASWGGGGRGMRVLESEQ
HHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCC
DLEPSLAAARREALAAFGNDEVYLEKLVRNARHVEVQILGDTHGNLVHLHERDCTVQRRN
CCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHH
QKVIERAPAPYMDAAGRASLCDAALRLMGAVGYSHAGTVEFLMDADTNKFYFIEVNPRIQ
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCEEE
VEHTVTEMITGIDIVKAQIRVTEGGRIGMTEDTLDENGDITTRAAGVPPQAQIPLNGHAL
EHHHHHHHHHCHHEEEEEEEEECCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEE
QCRITSEDPENGFLPDYGRLTAYRSAAGFGVRLDAGTAYGGAVITPYYDSLLVKVTTWAP
EEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCEEEEEEECCC
TAAESIRRMDRALREFRIRGVSSNLQFLENVINHPAFGSGDVTTRFIDLTPELLAFTKRR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHCC
DTATKLLSYLGDVSINGHQEMTGRAVPQLPLPRPVLPVVDTTRPLPLGTRDRLRELGAEK
HHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FASWMLDQKQVLLTDTTMRDAHQSLFATRMRTADMLPIAPFYASELSQLFSMECWGGATF
HHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
DVALRFLKEDPWQRLAQLRERVPNILFQMLLRGSNAVGYTNYADNVVRFFVKQAASTGVD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
VFRVFDSLNWVRNMRVAIDAVGETGALCEGAICYTGDLFDGSRPKYDLKYYVGIARELQR
HHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHH
AGVHVLGIKDMAGICRPQAAAALVKALKEETGLPVHFHTHDTSGISAASALAAIEAGCDA
CCEEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCH
VDGALDAMSGLTSQPNLSSIVAALAGSERDPGLSLDRLHEASMYWEGVRRYYAPFESEIR
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHC
AGTADVYRHEMPGGQYTNLREQARSLGIEHRWTEVSRAYADVNRMFGDIVKVTPTSKVVG
CCHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCHHHHH
DLALMMVANDMTAADVCDPNKEVAFPESVVSLFKGELGFPPDGFPAELSRKVLRGEPPAP
HHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCC
YRPGDLIPAVDLDVVRAQGEAACEQPLDDMQLASYLMYPKQTVEYHAHVRAYSDTSVLPT
CCCCCCCCCCCHHHHHCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHEEEEECCCCCCCC
PAYLYGLQPQEEVAVDIAAGKTLLVSLQGTHPDAEEGVIKVQFELNGQSRTALIEQRSTV
CHHEECCCCHHHHEEEEECCCEEEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHCCCCE
SVATARQGRQVADPENPLHIAAPMPGSIVTVAVQPGQRVAAGTTLLALEAMKMETHIAAD
EEHHHHCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
RDGEIAAVHVKPGDRVAAKDLLIELKG
CCCCEEEEEECCCCCEEHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]