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The map label for this gene is mocR [H]

Identifier: 94310551

GI number: 94310551

Start: 1735391

End: 1737100

Strand: Reverse

Name: mocR [H]

Synonym: Rmet_1609

Alternate gene names: 94310551

Gene position: 1737100-1735391 (Counterclockwise)

Preceding gene: 335055537

Following gene: 94310550

Centisome position: 44.22

GC content: 63.86

Gene sequence:

>1710_bases
ATGGGGGCTCCGCGATGGGGACATCGAAAAAAAACAGCATCAGCACGGATGGAAAATTATCCGATGGTTGGTACCATCGG
TAGGTCCATATCCTGTTTTTTGCCCGGAGCCACTTTGAAAGAGACGATTCTTTCCGACCTGCTGCTTCAGCGACTTGAGC
GCCCCGCTGGTGCAGTCACCGGCAAATCGGGCGAGCATATGAACCGACAGCTCTACGCCATCATCCGTCAGGAGATCCTT
GCAGGTGCTGTGCCAGCGGGTAGCAAGCTGCCGGCGTCGCGCCTGCTGGCCAAGGAAATCGGTGTCTCGCGCAACACCGT
CCTGTATGCGTACGAGCAGTTATTGGCCGAAGGCTATGTGACCGCATCCACCGGAAGTGGCACCTTCGTGTCGCATACCG
TTCCCGACCATCGTGCATTGCACAACGGGAGTGCGGCGAATGGCACCATCACTGTGCCCGCAGTGCAGCAACACCCAAAC
CGATTCGCGCTGTCGCGACGCGGGCAGCATCTGGTGTCCCACGCCAGCGCGTCGGATCGCCAATGGGGCGCGTTCGTCGC
AGGCGTGCCTGATGTCTCGCTATTTCCACACGCGGTCTGGGCGCGCCTGCTGAACAAGCACTGGCGCAATCCAAGCCCGC
AGTTGCTGACGTACGCGCATCACGGCGGCTACCTGCCGCTGAAGAAGCTGCTGGCCGAACACCTGCGTCTAGTGCGTTCC
GTGCGCTGCGAGCCGGACCAGATCATCCTGACCACCGGCATCCACCAGGCCGTGGACCTGACCACCCGGCTGCTGGCCGA
CCCCGGCGACAAGGCATGGATGGAAGATCCCGGCTACTGGGGCACACGCAGCCTGCTGGCAAGCGCGGGCGTGGAGCCAA
TCCCGGTACCGGTCGACGATGAAGGGATCGCGCCAAGCCCCGCGACGCTACAGAATCCGCCACGCTTCATCTTCGTCACG
CCTTCGCACCAGTATCCGCTTGGCATGATGATGAGCCTCTCGCGCCGGCGCATGTTGCTCGAATACGCGCGGCAGCGCGG
TGCATGGATCATCGAGGACGACTACGACAGCGAGTTCCGTTTCGAAGGCAGGCCGGTGGCGTCGTTGCAGGGGCTGGACG
ACAACGATCGCGTGATCTACATGGGCACGTTCTCGAAGACGCTCTTCCCGGGCATACGCATGGGCTTCATGGTGTTGCCC
AAGCCGCTGGCGCCCCACTTCGCCACGGGGCTGTCCGAGCTCTATCGCGAAGGCCAGCTCGTGCAGCAGGCGGTGCTGGC
GGACTTCATCGAGGAAGGCCACTACGCCACGCATATCCGTCGGATGCGCCAGCGGTACGCGCAGCGCCAGGCGCTGTTAC
GCGAAGCCATCGCCAACCGCTTCGGCGCCGACTGGCCCACATCCACGCATGAGGCCGGCCTGCACATGGTGATGCATCTG
CCGCGCGGCGCCGATGATCTTGGCATCAGCATGGCCGCGCGCACGCAGGGGCTATCGGCCCGGCCGCTTTCGCGCTACTA
CAGCGAGGGGGCGGCGACGCAACAAGGGCTGCTGCTCGGCTACGCGTGCGTGCCCGAAGCCGAGATCGGTCCGGCCTTCC
GCAAACTGGCCGAAGTCATCGAGCCGGCGCTGGAACATCTGGCGCGCACCCAGGAGCCGCCAAAACCGATTGCCGCGAGG
ATCAATGCAGAAGCGTGGAGCGGCGCTTGA

Upstream 100 bases:

>100_bases
GGTTTTCACCATGTACGGCGTGAGTGCGCGCACGGCATCGGCAATCGCCTGCGTGGTGAGCGTTGTCGATTCAGGAGACG
CAACGGTGGCTGCATTCGGC

Downstream 100 bases:

>100_bases
TGTCTGGTGCCATCACGAAGGTGACGAATGGCACTTTACGTTGCCGTGATGGATTCCTACGATCAGGTTTTGTCGCGCGG
CATACGCTGACCCTTTCCAT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MGAPRWGHRKKTASARMENYPMVGTIGRSISCFLPGATLKETILSDLLLQRLERPAGAVTGKSGEHMNRQLYAIIRQEIL
AGAVPAGSKLPASRLLAKEIGVSRNTVLYAYEQLLAEGYVTASTGSGTFVSHTVPDHRALHNGSAANGTITVPAVQQHPN
RFALSRRGQHLVSHASASDRQWGAFVAGVPDVSLFPHAVWARLLNKHWRNPSPQLLTYAHHGGYLPLKKLLAEHLRLVRS
VRCEPDQIILTTGIHQAVDLTTRLLADPGDKAWMEDPGYWGTRSLLASAGVEPIPVPVDDEGIAPSPATLQNPPRFIFVT
PSHQYPLGMMMSLSRRRMLLEYARQRGAWIIEDDYDSEFRFEGRPVASLQGLDDNDRVIYMGTFSKTLFPGIRMGFMVLP
KPLAPHFATGLSELYREGQLVQQAVLADFIEEGHYATHIRRMRQRYAQRQALLREAIANRFGADWPTSTHEAGLHMVMHL
PRGADDLGISMAARTQGLSARPLSRYYSEGAATQQGLLLGYACVPEAEIGPAFRKLAEVIEPALEHLARTQEPPKPIAAR
INAEAWSGA

Sequences:

>Translated_569_residues
MGAPRWGHRKKTASARMENYPMVGTIGRSISCFLPGATLKETILSDLLLQRLERPAGAVTGKSGEHMNRQLYAIIRQEIL
AGAVPAGSKLPASRLLAKEIGVSRNTVLYAYEQLLAEGYVTASTGSGTFVSHTVPDHRALHNGSAANGTITVPAVQQHPN
RFALSRRGQHLVSHASASDRQWGAFVAGVPDVSLFPHAVWARLLNKHWRNPSPQLLTYAHHGGYLPLKKLLAEHLRLVRS
VRCEPDQIILTTGIHQAVDLTTRLLADPGDKAWMEDPGYWGTRSLLASAGVEPIPVPVDDEGIAPSPATLQNPPRFIFVT
PSHQYPLGMMMSLSRRRMLLEYARQRGAWIIEDDYDSEFRFEGRPVASLQGLDDNDRVIYMGTFSKTLFPGIRMGFMVLP
KPLAPHFATGLSELYREGQLVQQAVLADFIEEGHYATHIRRMRQRYAQRQALLREAIANRFGADWPTSTHEAGLHMVMHL
PRGADDLGISMAARTQGLSARPLSRYYSEGAATQQGLLLGYACVPEAEIGPAFRKLAEVIEPALEHLARTQEPPKPIAAR
INAEAWSGA
>Mature_568_residues
GAPRWGHRKKTASARMENYPMVGTIGRSISCFLPGATLKETILSDLLLQRLERPAGAVTGKSGEHMNRQLYAIIRQEILA
GAVPAGSKLPASRLLAKEIGVSRNTVLYAYEQLLAEGYVTASTGSGTFVSHTVPDHRALHNGSAANGTITVPAVQQHPNR
FALSRRGQHLVSHASASDRQWGAFVAGVPDVSLFPHAVWARLLNKHWRNPSPQLLTYAHHGGYLPLKKLLAEHLRLVRSV
RCEPDQIILTTGIHQAVDLTTRLLADPGDKAWMEDPGYWGTRSLLASAGVEPIPVPVDDEGIAPSPATLQNPPRFIFVTP
SHQYPLGMMMSLSRRRMLLEYARQRGAWIIEDDYDSEFRFEGRPVASLQGLDDNDRVIYMGTFSKTLFPGIRMGFMVLPK
PLAPHFATGLSELYREGQLVQQAVLADFIEEGHYATHIRRMRQRYAQRQALLREAIANRFGADWPTSTHEAGLHMVMHLP
RGADDLGISMAARTQGLSARPLSRYYSEGAATQQGLLLGYACVPEAEIGPAFRKLAEVIEPALEHLARTQEPPKPIAARI
NAEAWSGA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=320, Percent_Identity=27.1875, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI33469970, Length=320, Percent_Identity=27.1875, Blast_Score=106, Evalue=6e-23,
Organism=Escherichia coli, GI1790797, Length=437, Percent_Identity=28.8329519450801, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1787710, Length=467, Percent_Identity=25.4817987152034, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 62709; Mature: 62577

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAPRWGHRKKTASARMENYPMVGTIGRSISCFLPGATLKETILSDLLLQRLERPAGAVT
CCCCCCCCCHHHHHHHHHCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCC
GKSGEHMNRQLYAIIRQEILAGAVPAGSKLPASRLLAKEIGVSRNTVLYAYEQLLAEGYV
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCE
TASTGSGTFVSHTVPDHRALHNGSAANGTITVPAVQQHPNRFALSRRGQHLVSHASASDR
EEECCCCCEEECCCCCHHHHCCCCCCCCEEEECHHHHCCCHHHHHHHHHHHHHHCCCCCC
QWGAFVAGVPDVSLFPHAVWARLLNKHWRNPSPQLLTYAHHGGYLPLKKLLAEHLRLVRS
CCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VRCEPDQIILTTGIHQAVDLTTRLLADPGDKAWMEDPGYWGTRSLLASAGVEPIPVPVDD
HCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
EGIAPSPATLQNPPRFIFVTPSHQYPLGMMMSLSRRRMLLEYARQRGAWIIEDDYDSEFR
CCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
FEGRPVASLQGLDDNDRVIYMGTFSKTLFPGIRMGFMVLPKPLAPHFATGLSELYREGQL
ECCCCCHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VQQAVLADFIEEGHYATHIRRMRQRYAQRQALLREAIANRFGADWPTSTHEAGLHMVMHL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEC
PRGADDLGISMAARTQGLSARPLSRYYSEGAATQQGLLLGYACVPEAEIGPAFRKLAEVI
CCCCCHHCCCHHHHHCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHH
EPALEHLARTQEPPKPIAARINAEAWSGA
HHHHHHHHHCCCCCCCHHHEECCCCCCCC
>Mature Secondary Structure 
GAPRWGHRKKTASARMENYPMVGTIGRSISCFLPGATLKETILSDLLLQRLERPAGAVT
CCCCCCCCHHHHHHHHHCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCC
GKSGEHMNRQLYAIIRQEILAGAVPAGSKLPASRLLAKEIGVSRNTVLYAYEQLLAEGYV
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCE
TASTGSGTFVSHTVPDHRALHNGSAANGTITVPAVQQHPNRFALSRRGQHLVSHASASDR
EEECCCCCEEECCCCCHHHHCCCCCCCCEEEECHHHHCCCHHHHHHHHHHHHHHCCCCCC
QWGAFVAGVPDVSLFPHAVWARLLNKHWRNPSPQLLTYAHHGGYLPLKKLLAEHLRLVRS
CCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VRCEPDQIILTTGIHQAVDLTTRLLADPGDKAWMEDPGYWGTRSLLASAGVEPIPVPVDD
HCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
EGIAPSPATLQNPPRFIFVTPSHQYPLGMMMSLSRRRMLLEYARQRGAWIIEDDYDSEFR
CCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
FEGRPVASLQGLDDNDRVIYMGTFSKTLFPGIRMGFMVLPKPLAPHFATGLSELYREGQL
ECCCCCHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VQQAVLADFIEEGHYATHIRRMRQRYAQRQALLREAIANRFGADWPTSTHEAGLHMVMHL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEC
PRGADDLGISMAARTQGLSARPLSRYYSEGAATQQGLLLGYACVPEAEIGPAFRKLAEVI
CCCCCHHCCCHHHHHCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHH
EPALEHLARTQEPPKPIAARINAEAWSGA
HHHHHHHHHCCCCCCCHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]