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The map label for this gene is hypA2 [H]

Identifier: 94310477

GI number: 94310477

Start: 1655561

End: 1655902

Strand: Direct

Name: hypA2 [H]

Synonym: Rmet_1535

Alternate gene names: 94310477

Gene position: 1655561-1655902 (Clockwise)

Preceding gene: 335055532

Following gene: 94310478

Centisome position: 42.15

GC content: 67.84

Gene sequence:

>342_bases
ATGCATGAGATGTCGCTGGCCGAGGGCGTGCTGCAGATCGTCGAGGACGCGGCACGGAGCCAAGGCTTCTCCCAAGTGAC
CGCGGTGAGGCTGGAGATCGGCCGGCTGTCCAGCGTCGAGCCGGAGGCGCTGCGCTTCTGCTTCGACGTGGTGGTGCGCG
GCAGCCTGGCGGAAGGGGCGCGTCTGGAGATCGTGGATATCCCCGGCACGGGCTGGTGCCTGCAGTGCAGTGAGACGGTG
CCGGTCAATGCGCTGTACGACTCCTGCCCGCGCTGCGGCAGCAGCCAGGTGCAGCCCACTGGCGGCACGGAAATGCGCGT
CAGGGATCTGGAAGTGGCGTAA

Upstream 100 bases:

>100_bases
CTCGGCAAGCGCGCGACCGACGACGAGACATTGAAAACCTATCTGGACGCCTTGGCGCTGACGCTCGATCCCTGCGTCGC
TGACGAGGTCAGGCTGCACG

Downstream 100 bases:

>100_bases
CCTCACGTCAGGACAAGGAGACAGAATCGAATCATGTGTACCATCTGCGGCTGCGGCGCCGGCGAAACCCGCATCGAAGG
CCAGGAACTGGAGCATACGC

Product: hydrogenase nickel incorporation protein hypA (Protein hupA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHEMSLAEGVLQIVEDAARSQGFSQVTAVRLEIGRLSSVEPEALRFCFDVVVRGSLAEGARLEIVDIPGTGWCLQCSETV
PVNALYDSCPRCGSSQVQPTGGTEMRVRDLEVA

Sequences:

>Translated_113_residues
MHEMSLAEGVLQIVEDAARSQGFSQVTAVRLEIGRLSSVEPEALRFCFDVVVRGSLAEGARLEIVDIPGTGWCLQCSETV
PVNALYDSCPRCGSSQVQPTGGTEMRVRDLEVA
>Mature_113_residues
MHEMSLAEGVLQIVEDAARSQGFSQVTAVRLEIGRLSSVEPEALRFCFDVVVRGSLAEGARLEIVDIPGTGWCLQCSETV
PVNALYDSCPRCGSSQVQPTGGTEMRVRDLEVA

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=38.3928571428571, Blast_Score=90, Evalue=4e-20,
Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=35.3982300884956, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 12184; Mature: 12184

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMSLAEGVLQIVEDAARSQGFSQVTAVRLEIGRLSSVEPEALRFCFDVVVRGSLAEGA
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
RLEIVDIPGTGWCLQCSETVPVNALYDSCPRCGSSQVQPTGGTEMRVRDLEVA
EEEEEECCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MHEMSLAEGVLQIVEDAARSQGFSQVTAVRLEIGRLSSVEPEALRFCFDVVVRGSLAEGA
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
RLEIVDIPGTGWCLQCSETVPVNALYDSCPRCGSSQVQPTGGTEMRVRDLEVA
EEEEEECCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA