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The map label for this gene is pyrH [H]

Identifier: 94310379

GI number: 94310379

Start: 1558348

End: 1559124

Strand: Direct

Name: pyrH [H]

Synonym: Rmet_1437

Alternate gene names: 94310379

Gene position: 1558348-1559124 (Clockwise)

Preceding gene: 94310378

Following gene: 94310380

Centisome position: 39.67

GC content: 62.68

Gene sequence:

>777_bases
ATGCTTCGTGCCGCCCGCGCCCACCCTCCGTTCAAACGAGCGATCAAGAACCAGCCCGAGGTGAACATGCCTGCCTATAA
GCGCGTCCTTCTGAAATTGTCCGGTGAAGCCCTGATGGGCGACGATGCCTTCGGTATCAACCGTGCCACCATCGAGGGCA
TGGTCAATGACATTGCCGAAATCGTGAAGCTGGGTGTCCAGGTCGCGGTCGTCATCGGCGGCGGTAATATCTTCCGCGGT
GTCGCTGGCGGTGCTGCCGGCATGGACCGCGCCACGGCCGATTACATGGGTATGCTGGCCACGATGATGAATGCGCTGGC
CTTGCAGGACGCGATGCGCCACGCCAGCATCGAAGGCCGTGTGCAGTCCGCGCTGCGCATGGACCAGGTCGTCGAGCCGT
ATATCCGCCCGCGCGCGATTCGCCAGCTCGAAGAGGGCAAGGTGGTGATCTTCGCCGCCGGCACCGGCAACCCGTTCTTC
ACGACCGATACGGCCGCGGCGCTGCGTGGCTCTGAAATCGGTGCCGAAATCGTGCTCAAGGCGACCAAGGTGGACGGCGT
GTATACCGCCGATCCCAAGAAGGATCCGAGCGCCACGCGCTACACGACCATCTCGTTCGACGAAGCCATTTCCCGCAACC
TGCAGGTCATGGACGCCACCGCGTTCGCGCTGTGCCGTGACCAGAAGCTGCCAATCAAGGTGTTTTCGATCGTCAAGCCG
GGCGCACTGAAGCGCGTGATCCTGGGCGAGGATGAGGGCACGCTGGTGCACGTTTAA

Upstream 100 bases:

>100_bases
GGCATTTCGCGCGTCTTTTGACAGATGTTGCGGGCAGATGACAGCGAAAACCGGCTTGTCTCAGTCAAGCGATCCGTATT
TTTGCGCGGCCGGTGCGCAG

Downstream 100 bases:

>100_bases
GGGGCGGGGACCGCATCTGGATGCGGATTCGGTCCTTCCTCAGAGTAGAATGTTTCATTTTCGATCCCGCTGGGCGGGAT
CATGTCTGGCCGTTTTTCGG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLRAARAHPPFKRAIKNQPEVNMPAYKRVLLKLSGEALMGDDAFGINRATIEGMVNDIAEIVKLGVQVAVVIGGGNIFRG
VAGGAAGMDRATADYMGMLATMMNALALQDAMRHASIEGRVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFF
TTDTAAALRGSEIGAEIVLKATKVDGVYTADPKKDPSATRYTTISFDEAISRNLQVMDATAFALCRDQKLPIKVFSIVKP
GALKRVILGEDEGTLVHV

Sequences:

>Translated_258_residues
MLRAARAHPPFKRAIKNQPEVNMPAYKRVLLKLSGEALMGDDAFGINRATIEGMVNDIAEIVKLGVQVAVVIGGGNIFRG
VAGGAAGMDRATADYMGMLATMMNALALQDAMRHASIEGRVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFF
TTDTAAALRGSEIGAEIVLKATKVDGVYTADPKKDPSATRYTTISFDEAISRNLQVMDATAFALCRDQKLPIKVFSIVKP
GALKRVILGEDEGTLVHV
>Mature_258_residues
MLRAARAHPPFKRAIKNQPEVNMPAYKRVLLKLSGEALMGDDAFGINRATIEGMVNDIAEIVKLGVQVAVVIGGGNIFRG
VAGGAAGMDRATADYMGMLATMMNALALQDAMRHASIEGRVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFF
TTDTAAALRGSEIGAEIVLKATKVDGVYTADPKKDPSATRYTTISFDEAISRNLQVMDATAFALCRDQKLPIKVFSIVKP
GALKRVILGEDEGTLVHV

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=56.6523605150215, Blast_Score=280, Evalue=6e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27715; Mature: 27715

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRAARAHPPFKRAIKNQPEVNMPAYKRVLLKLSGEALMGDDAFGINRATIEGMVNDIAE
CCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHH
IVKLGVQVAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHASIEGR
HHHCCEEEEEEEECCCEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEIGAEIVLK
HHHHHHHHHHHHHHHCHHHHHHHCCCCEEEEEECCCCCCEECCHHHHHCCCCCCCEEEEE
ATKVDGVYTADPKKDPSATRYTTISFDEAISRNLQVMDATAFALCRDQKLPIKVFSIVKP
EEECCCEEECCCCCCCCCCEEEEEEHHHHHHCCCEEEHHHHHHHHCCCCCCEEEEEEECC
GALKRVILGEDEGTLVHV
CCCEEEEEECCCCCEEEC
>Mature Secondary Structure
MLRAARAHPPFKRAIKNQPEVNMPAYKRVLLKLSGEALMGDDAFGINRATIEGMVNDIAE
CCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHH
IVKLGVQVAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHASIEGR
HHHCCEEEEEEEECCCEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEIGAEIVLK
HHHHHHHHHHHHHHHCHHHHHHHCCCCEEEEEECCCCCCEECCHHHHHCCCCCCCEEEEE
ATKVDGVYTADPKKDPSATRYTTISFDEAISRNLQVMDATAFALCRDQKLPIKVFSIVKP
EEECCCEEECCCCCCCCCCEEEEEEHHHHHHCCCEEEHHHHHHHHCCCCCCEEEEEEECC
GALKRVILGEDEGTLVHV
CCCEEEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA