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The map label for this gene is frr [H]

Identifier: 94310380

GI number: 94310380

Start: 1559233

End: 1559793

Strand: Direct

Name: frr [H]

Synonym: Rmet_1438

Alternate gene names: 94310380

Gene position: 1559233-1559793 (Clockwise)

Preceding gene: 94310379

Following gene: 94310381

Centisome position: 39.69

GC content: 60.78

Gene sequence:

>561_bases
ATGACCGTCGCCGACACTAAGAAGAGCGTCGAGCAGAAGATGCAGAAGTCGATCGAAGCTTTCAAGGCCGATCTGGCGAA
AGTTCGTACCGGCCGCGCTCATACCGGCTTGCTTGACCATGTTCAGGTGGATTACTACGGCTCGATGGTGCCGATCAGCC
AGGTGGCTGCAGTCAGCCTTGCCGACGCCCGCACGATCTCCGTGCAGCCCTGGGAAAAGAAGATGGTCCAGGCTGTGGAA
AAGGCGATTCGCGACGGCGATCTGGGCCTGAACCCGGCCACGATGGGCGACGTGATCCGCGTGCCGATGCCCCCGCTGAC
CGAAGAGCGCCGCAGGGAGCTGACCAAGGTCGTCAAGGGCGAAGCCGAAGGCGCCAAGGTGGCCGTGCGCAACCTGCGCC
GCGACGCCAACGAGCAGTTCAAGAAGCTGGTCAAGGACAAGGCAATTTCCGAGGACGACGAGCGTCGCGGTCAGGACGAA
GTGCAGAAGCTCACGGACAAGTTCGTGGCCGAAATCGACAAGCTCGTTGCCGAGAAAGAGAAGGAGATCATGACGGTGTA
A

Upstream 100 bases:

>100_bases
GACCGCATCTGGATGCGGATTCGGTCCTTCCTCAGAGTAGAATGTTTCATTTTCGATCCCGCTGGGCGGGATCATGTCTG
GCCGTTTTTCGGAGGTAATC

Downstream 100 bases:

>100_bases
GGCCGTCCTGGCGGCCGAGCCGCCAGGGTTGCCGGATATCGTCCGCGAATCCATGCAGCACATCAGTTCGACGCTAGGCG
TTCCCGATACCACCTATGTG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTVADTKKSVEQKMQKSIEAFKADLAKVRTGRAHTGLLDHVQVDYYGSMVPISQVAAVSLADARTISVQPWEKKMVQAVE
KAIRDGDLGLNPATMGDVIRVPMPPLTEERRRELTKVVKGEAEGAKVAVRNLRRDANEQFKKLVKDKAISEDDERRGQDE
VQKLTDKFVAEIDKLVAEKEKEIMTV

Sequences:

>Translated_186_residues
MTVADTKKSVEQKMQKSIEAFKADLAKVRTGRAHTGLLDHVQVDYYGSMVPISQVAAVSLADARTISVQPWEKKMVQAVE
KAIRDGDLGLNPATMGDVIRVPMPPLTEERRRELTKVVKGEAEGAKVAVRNLRRDANEQFKKLVKDKAISEDDERRGQDE
VQKLTDKFVAEIDKLVAEKEKEIMTV
>Mature_185_residues
TVADTKKSVEQKMQKSIEAFKADLAKVRTGRAHTGLLDHVQVDYYGSMVPISQVAAVSLADARTISVQPWEKKMVQAVEK
AIRDGDLGLNPATMGDVIRVPMPPLTEERRRELTKVVKGEAEGAKVAVRNLRRDANEQFKKLVKDKAISEDDERRGQDEV
QKLTDKFVAEIDKLVAEKEKEIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=32.3863636363636, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=32.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=54.9450549450549, Blast_Score=213, Evalue=8e-57,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=30.1136363636364, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20815; Mature: 20684

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVADTKKSVEQKMQKSIEAFKADLAKVRTGRAHTGLLDHVQVDYYGSMVPISQVAAVSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHHHHHHCCCCCHHHHHHHHHH
ADARTISVQPWEKKMVQAVEKAIRDGDLGLNPATMGDVIRVPMPPLTEERRRELTKVVKG
HCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCEEECCCCCCCHHHHHHHHHHHHC
EAEGAKVAVRNLRRDANEQFKKLVKDKAISEDDERRGQDEVQKLTDKFVAEIDKLVAEKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KEIMTV
HHHCCC
>Mature Secondary Structure 
TVADTKKSVEQKMQKSIEAFKADLAKVRTGRAHTGLLDHVQVDYYGSMVPISQVAAVSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHHHHHHCCCCCHHHHHHHHHH
ADARTISVQPWEKKMVQAVEKAIRDGDLGLNPATMGDVIRVPMPPLTEERRRELTKVVKG
HCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCEEECCCCCCCHHHHHHHHHHHHC
EAEGAKVAVRNLRRDANEQFKKLVKDKAISEDDERRGQDEVQKLTDKFVAEIDKLVAEKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
KEIMTV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA