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The map label for this gene is ephD [H]

Identifier: 94310326

GI number: 94310326

Start: 1492490

End: 1493452

Strand: Direct

Name: ephD [H]

Synonym: Rmet_1384

Alternate gene names: 94310326

Gene position: 1492490-1493452 (Clockwise)

Preceding gene: 94310325

Following gene: 94310327

Centisome position: 38.0

GC content: 66.25

Gene sequence:

>963_bases
ATGACCCCTGTAGATTCCGCACATCCTGAGTTCCCTCCGCCCGCTCCGACACACTTCGCCGTGCAGTCCGGCCCAGTGAG
GCTGGCTGCCACAGCGTGGGGCGATCCGGGCCATCCGGTGGTCGTGCTCGTGCACGGCTATCCGGACAACAGCCATGTCT
GGCATGGCGTGGCGCAAGCCTTGGCCGGCCGCTTCCGTGTGGTGGCCTACGATGTGCGCGGTGCTGGGGCATCCGATGTG
CCGGCTGGCGTGGCGGATTACCGGCTCGAACGCCTGGCCGACGACTTCATCGCTGTCATCGACGCGGTGTCGCCGGATCG
GCCGGTGCATCTGGTGGGCCACGACTGGGGTTCGATCCAGGGATGGGAGTTCGTGACTGATCCGCGTCTCTACGGTCGCA
TCGCCTCGTTCACCTCCTGTTCCGGGCCTTGCCTCGATCACGCCGCCCGCGCGTTGCGCGAGCCGCCCCGGCACTGGGGC
GCCACGCTGCGTCAGGCACTGGCATCGTGGTACATCGTGTTCTTCCATATTCCCGGCTTGCCAGAGTGGAACTGGAAACT
CTGGCTGGGACGTAACTGGACGTTCTGGCTGCGCCGGACGGAAGGGCTCCATACCGCCGCCAACCCGACGCAGACCGCCG
ATGGCGTCCATGGCCTGCGCCTGTACCGCGCCAACATCAGAACCCGATTGCGTCATCCGCACAACCGCCACGCGCACGCG
CCGGTGCAGGTGATTGTGCCGACACGCGACCGCTATGTGCGCCCCGCCGTGACGGAAGGCGTGGGACGCTGGGCCGCACA
GTCGTGGCGGCGTCCCGTGGATGCCCACCACTGGTTTCCACTTGCCGATCCTCACCGCATGGCGGCAATGGTGCGCGAAT
TTGTCGACCATCTTCAGGGCGCGCCAGCGTCCCCCGCGCTGCAATCTGCACGTGTTACGTCGGAGGCAGGCAAAATTTCA
TAA

Upstream 100 bases:

>100_bases
GCTGCCTGACGGCAGAAGAATCGCGTTTCAAACGCCGTTGCCCGGTGCGCGGCGGCGTTAGCATGGCCGACGATGACATC
CTTCACTGTCAACGGACGCC

Downstream 100 bases:

>100_bases
TGCGGAAAGATGTTTTGTTTCGCAAAAATACGAGCGTGCGGGGCACAAGAGGGTTTCTCATGATGAAAGATTGCTTGCCG
TATGGTGGAAAGATTGATCT

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTPVDSAHPEFPPPAPTHFAVQSGPVRLAATAWGDPGHPVVVLVHGYPDNSHVWHGVAQALAGRFRVVAYDVRGAGASDV
PAGVADYRLERLADDFIAVIDAVSPDRPVHLVGHDWGSIQGWEFVTDPRLYGRIASFTSCSGPCLDHAARALREPPRHWG
ATLRQALASWYIVFFHIPGLPEWNWKLWLGRNWTFWLRRTEGLHTAANPTQTADGVHGLRLYRANIRTRLRHPHNRHAHA
PVQVIVPTRDRYVRPAVTEGVGRWAAQSWRRPVDAHHWFPLADPHRMAAMVREFVDHLQGAPASPALQSARVTSEAGKIS

Sequences:

>Translated_320_residues
MTPVDSAHPEFPPPAPTHFAVQSGPVRLAATAWGDPGHPVVVLVHGYPDNSHVWHGVAQALAGRFRVVAYDVRGAGASDV
PAGVADYRLERLADDFIAVIDAVSPDRPVHLVGHDWGSIQGWEFVTDPRLYGRIASFTSCSGPCLDHAARALREPPRHWG
ATLRQALASWYIVFFHIPGLPEWNWKLWLGRNWTFWLRRTEGLHTAANPTQTADGVHGLRLYRANIRTRLRHPHNRHAHA
PVQVIVPTRDRYVRPAVTEGVGRWAAQSWRRPVDAHHWFPLADPHRMAAMVREFVDHLQGAPASPALQSARVTSEAGKIS
>Mature_319_residues
TPVDSAHPEFPPPAPTHFAVQSGPVRLAATAWGDPGHPVVVLVHGYPDNSHVWHGVAQALAGRFRVVAYDVRGAGASDVP
AGVADYRLERLADDFIAVIDAVSPDRPVHLVGHDWGSIQGWEFVTDPRLYGRIASFTSCSGPCLDHAARALREPPRHWGA
TLRQALASWYIVFFHIPGLPEWNWKLWLGRNWTFWLRRTEGLHTAANPTQTADGVHGLRLYRANIRTRLRHPHNRHAHAP
VQVIVPTRDRYVRPAVTEGVGRWAAQSWRRPVDAHHWFPLADPHRMAAMVREFVDHLQGAPASPALQSARVTSEAGKIS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=168, Percent_Identity=27.9761904761905, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI218777840, Length=298, Percent_Identity=25.503355704698, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI13376164, Length=298, Percent_Identity=25.503355704698, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554012, Length=294, Percent_Identity=22.108843537415, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562298, Length=167, Percent_Identity=28.7425149700599, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 35611; Mature: 35479

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVDSAHPEFPPPAPTHFAVQSGPVRLAATAWGDPGHPVVVLVHGYPDNSHVWHGVAQA
CCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHH
LAGRFRVVAYDVRGAGASDVPAGVADYRLERLADDFIAVIDAVSPDRPVHLVGHDWGSIQ
HCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
GWEFVTDPRLYGRIASFTSCSGPCLDHAARALREPPRHWGATLRQALASWYIVFFHIPGL
CCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEECCCC
PEWNWKLWLGRNWTFWLRRTEGLHTAANPTQTADGVHGLRLYRANIRTRLRHPHNRHAHA
CCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
PVQVIVPTRDRYVRPAVTEGVGRWAAQSWRRPVDAHHWFPLADPHRMAAMVREFVDHLQG
CEEEEECCCCCEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
APASPALQSARVTSEAGKIS
CCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPVDSAHPEFPPPAPTHFAVQSGPVRLAATAWGDPGHPVVVLVHGYPDNSHVWHGVAQA
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHH
LAGRFRVVAYDVRGAGASDVPAGVADYRLERLADDFIAVIDAVSPDRPVHLVGHDWGSIQ
HCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
GWEFVTDPRLYGRIASFTSCSGPCLDHAARALREPPRHWGATLRQALASWYIVFFHIPGL
CCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEECCCC
PEWNWKLWLGRNWTFWLRRTEGLHTAANPTQTADGVHGLRLYRANIRTRLRHPHNRHAHA
CCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
PVQVIVPTRDRYVRPAVTEGVGRWAAQSWRRPVDAHHWFPLADPHRMAAMVREFVDHLQG
CEEEEECCCCCEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
APASPALQSARVTSEAGKIS
CCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]