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The map label for this gene is hoxM [H]

Identifier: 94310237

GI number: 94310237

Start: 1409791

End: 1410456

Strand: Reverse

Name: hoxM [H]

Synonym: Rmet_1293

Alternate gene names: 94310237

Gene position: 1410456-1409791 (Counterclockwise)

Preceding gene: 94310238

Following gene: 94310236

Centisome position: 35.91

GC content: 69.07

Gene sequence:

>666_bases
ATGCGCACCACTCCGACCGAATCCACCTGTCACCCCGGTGGTGACACTCTGCCGGCCCGCATCGTCGTGCTGGGCATCGG
CAACCTGCTCTGGGCCGACGAAGGCTTTGGCGTGCGCTGCATCGAAGCCCTGCAGCGCCGCTGGGAGTTCGCCGACCACG
TGCAGCTGATCGACGGCGGCACCCAGGGCCTGTACCTGATCCAGCACGTGCAGGAGGCCGACCGCCTGCTCATCTTCGAC
GCCATCGACTACGGCCTGGCGCCCGGCACCTTGAAGCTGGTGCGAGACGACGACGTGCCGCGCTTCATGGGCGCCAAGAA
GATGAGCCTGCACCAGACCGGTTTCCAGGAAGTGCTGTCGCTGGCCACGCTGACCGGCAAGTACCCGCAGCAGGTGCTGC
TGATCGGCTGCCAGCCGCAGGAGCTGGAAGACTACGGCGGCAGCCTGCGCCCGGTCGTCAAGGCCGCGATGGAGGACGCA
CTGGCGCTGGGCGTGGCCGAACTCGAACGCTGGGGCGCACGCCCCGTCGAACGCCGGACCCCGTTGGCCCCGCGCGAGGC
CGTGACGTTGGACGAGCTGGCGCTGACCGCCTACGAAGCGCAGCGACCCGCCGCGGAAGAAGCCTGCCGCATCGGCGACG
ACCGGCTCCTGGTGAAGGACCTCTGA

Upstream 100 bases:

>100_bases
GCAGCAGGCCGCCTGGGACAGCTTCCACGCCTGGAAGCGCCTGTCCTCGGGTTCGGCCACGTCCCCTTTCCCCCGCTGAT
TTCACACAGGCTTGCCTGCC

Downstream 100 bases:

>100_bases
CATGTGCATCGGCATCCCCATGCAGGTGGTCGAGGCCGATGGCCGCTTCGCCTTGTGCGAAGGCCGCGGCGAGCGCCGCC
GCATCAACACCGCCCTGGTC

Product: nickel metalloprotease HoxM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRTTPTESTCHPGGDTLPARIVVLGIGNLLWADEGFGVRCIEALQRRWEFADHVQLIDGGTQGLYLIQHVQEADRLLIFD
AIDYGLAPGTLKLVRDDDVPRFMGAKKMSLHQTGFQEVLSLATLTGKYPQQVLLIGCQPQELEDYGGSLRPVVKAAMEDA
LALGVAELERWGARPVERRTPLAPREAVTLDELALTAYEAQRPAAEEACRIGDDRLLVKDL

Sequences:

>Translated_221_residues
MRTTPTESTCHPGGDTLPARIVVLGIGNLLWADEGFGVRCIEALQRRWEFADHVQLIDGGTQGLYLIQHVQEADRLLIFD
AIDYGLAPGTLKLVRDDDVPRFMGAKKMSLHQTGFQEVLSLATLTGKYPQQVLLIGCQPQELEDYGGSLRPVVKAAMEDA
LALGVAELERWGARPVERRTPLAPREAVTLDELALTAYEAQRPAAEEACRIGDDRLLVKDL
>Mature_221_residues
MRTTPTESTCHPGGDTLPARIVVLGIGNLLWADEGFGVRCIEALQRRWEFADHVQLIDGGTQGLYLIQHVQEADRLLIFD
AIDYGLAPGTLKLVRDDDVPRFMGAKKMSLHQTGFQEVLSLATLTGKYPQQVLLIGCQPQELEDYGGSLRPVVKAAMEDA
LALGVAELERWGARPVERRTPLAPREAVTLDELALTAYEAQRPAAEEACRIGDDRLLVKDL

Specific function: Absolutely required for hydrogenase activity. Mediates the attachment of hydrogenase to the bacterial membrane; attachment is a requirement for enzymatic activity [H]

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family [H]

Homologues:

Organism=Escherichia coli, GI1787209, Length=183, Percent_Identity=45.9016393442623, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789367, Length=170, Percent_Identity=41.1764705882353, Blast_Score=124, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004419
- InterPro:   IPR000671 [H]

Pfam domain/function: PF01750 HycI [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 24344; Mature: 24344

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTPTESTCHPGGDTLPARIVVLGIGNLLWADEGFGVRCIEALQRRWEFADHVQLIDGG
CCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHEEEECCC
TQGLYLIQHVQEADRLLIFDAIDYGLAPGTLKLVRDDDVPRFMGAKKMSLHQTGFQEVLS
CCHHHHHHHHHHHCCEEEEEHHHHCCCCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHHH
LATLTGKYPQQVLLIGCQPQELEDYGGSLRPVVKAAMEDALALGVAELERWGARPVERRT
HHHHCCCCCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCC
PLAPREAVTLDELALTAYEAQRPAAEEACRIGDDRLLVKDL
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MRTTPTESTCHPGGDTLPARIVVLGIGNLLWADEGFGVRCIEALQRRWEFADHVQLIDGG
CCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHEEEECCC
TQGLYLIQHVQEADRLLIFDAIDYGLAPGTLKLVRDDDVPRFMGAKKMSLHQTGFQEVLS
CCHHHHHHHHHHHCCEEEEEHHHHCCCCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHHH
LATLTGKYPQQVLLIGCQPQELEDYGGSLRPVVKAAMEDALALGVAELERWGARPVERRT
HHHHCCCCCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCC
PLAPREAVTLDELALTAYEAQRPAAEEACRIGDDRLLVKDL
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Ni [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1383192; 12948488 [H]