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The map label for this gene is hypB1 [H]

Identifier: 94310229

GI number: 94310229

Start: 1404829

End: 1405866

Strand: Reverse

Name: hypB1 [H]

Synonym: Rmet_1285

Alternate gene names: 94310229

Gene position: 1405866-1404829 (Counterclockwise)

Preceding gene: 94310230

Following gene: 94310228

Centisome position: 35.79

GC content: 64.35

Gene sequence:

>1038_bases
ATGTGTGTCGTATGCGGATGCAGTGACAACAGCCCGACTCATGCGCGGCATGTGCAACAGGCCAGCGGTGAGCCCGGCGT
GATCACGGTGAATCCGGCCAATGGCGACCTTCACTTCGGCGCCGGTGTGGCCCGCGTGTCGGTGCCGGGCATGAGCCAGG
AACGCGCCATCAAACTGGAGACCGACATCCTGGGCGCCAACAACCGTGTGGCACAGCAGAACCGTGCCCACTTCGAATTG
CATGGCGTGACCGCGCTGAACGTCGTCTCCAGCCCCGGCTCGGGCAAAACCACGCTGCTGTGCGCGACCATCGAGGCGCT
CAAAGCAAGGCAACCGGGCCTGCACGTGGCCGTGATCGAGGGCGACCAGCAGACCAGCTTCGACGCCGATCGCATCCGCG
CGACCGGCGCACCCGCCATCCAGGTCAACACAGGCAAAGGCTGTCACCTGGACGCGCCCATGGTGGCCGAGGCGTTTGCG
AAGCTGCACACGCATGAGCATGCAGACGGGCATTCTCACGACCATGTGCATGACCGCCACGGCCATCACCATGGTCATGG
TCATGGTCATGAGCACGATCATCACCACCACGGCGATGCCCACAGTCTGCTGTTCATCGAGAACGTGGGCAATCTGGTCT
GCCCCGCCATGTGGGACCTGGGCGAAGCCGCCAAGGTGGCCATCCTCTCGGTGACCGAGGGCGAGGACAAGCCGCTGAAG
TACCCCGACATGTTCGCGGCCTCGCAGCTCATGATCCTGAACAAGACCGACCTGCTGCCGCACGTGAAGTTCGACGTGGC
GCGCTGCATTGCCCTGGCGCGGCGCGTGAACCCGGCCATCGAGGTGATTCAGCTCTCGGCCACCACCGGCGAGGGCATGG
ACGCGTGGTTGCACTGGCTGGACCACGCGATGAGTACCCATCACCATCATCACGACGAAACGGTGTCCGAGGAAGCAGCA
CTGCGTGAGCGCGTGAAGCAGCTCGAAGCCGAGCTGGCCCGCGCGAAAGCAGTCCTGTCCGCCAAGACCCCGATCTGA

Upstream 100 bases:

>100_bases
CCTGCGGTGGCTACCAACTGCAGCCCACGGGCGGCATGGAATTGCGCATCATTGACATGAAAGTCAGTGATGATTGAAAC
CCGTTTGAAGGAGACCCAGC

Downstream 100 bases:

>100_bases
GAGACACGACCCCATGAGCGCAACCGTGCTCGCCGTCGGCGCCTGGCTGAAAAACGCGGCCTGCCTCGTGCTGGACGGCC
GCGCGCACTGGTCGCCGGTG

Product: GTP hydrolase HypB1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MCVVCGCSDNSPTHARHVQQASGEPGVITVNPANGDLHFGAGVARVSVPGMSQERAIKLETDILGANNRVAQQNRAHFEL
HGVTALNVVSSPGSGKTTLLCATIEALKARQPGLHVAVIEGDQQTSFDADRIRATGAPAIQVNTGKGCHLDAPMVAEAFA
KLHTHEHADGHSHDHVHDRHGHHHGHGHGHEHDHHHHGDAHSLLFIENVGNLVCPAMWDLGEAAKVAILSVTEGEDKPLK
YPDMFAASQLMILNKTDLLPHVKFDVARCIALARRVNPAIEVIQLSATTGEGMDAWLHWLDHAMSTHHHHHDETVSEEAA
LRERVKQLEAELARAKAVLSAKTPI

Sequences:

>Translated_345_residues
MCVVCGCSDNSPTHARHVQQASGEPGVITVNPANGDLHFGAGVARVSVPGMSQERAIKLETDILGANNRVAQQNRAHFEL
HGVTALNVVSSPGSGKTTLLCATIEALKARQPGLHVAVIEGDQQTSFDADRIRATGAPAIQVNTGKGCHLDAPMVAEAFA
KLHTHEHADGHSHDHVHDRHGHHHGHGHGHEHDHHHHGDAHSLLFIENVGNLVCPAMWDLGEAAKVAILSVTEGEDKPLK
YPDMFAASQLMILNKTDLLPHVKFDVARCIALARRVNPAIEVIQLSATTGEGMDAWLHWLDHAMSTHHHHHDETVSEEAA
LRERVKQLEAELARAKAVLSAKTPI
>Mature_345_residues
MCVVCGCSDNSPTHARHVQQASGEPGVITVNPANGDLHFGAGVARVSVPGMSQERAIKLETDILGANNRVAQQNRAHFEL
HGVTALNVVSSPGSGKTTLLCATIEALKARQPGLHVAVIEGDQQTSFDADRIRATGAPAIQVNTGKGCHLDAPMVAEAFA
KLHTHEHADGHSHDHVHDRHGHHHGHGHGHEHDHHHHGDAHSLLFIENVGNLVCPAMWDLGEAAKVAILSVTEGEDKPLK
YPDMFAASQLMILNKTDLLPHVKFDVARCIALARRVNPAIEVIQLSATTGEGMDAWLHWLDHAMSTHHHHHDETVSEEAA
LRERVKQLEAELARAKAVLSAKTPI

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=322, Percent_Identity=50, Blast_Score=292, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 37240; Mature: 37240

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVVCGCSDNSPTHARHVQQASGEPGVITVNPANGDLHFGAGVARVSVPGMSQERAIKLE
CEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEECCCEEEEECCCCCCCCEEEEE
TDILGANNRVAQQNRAHFELHGVTALNVVSSPGSGKTTLLCATIEALKARQPGLHVAVIE
EEEECCCCCHHHCCCCEEEEECEEEEEEECCCCCCCEEEEEEEHHHHHCCCCCCEEEEEE
GDQQTSFDADRIRATGAPAIQVNTGKGCHLDAPMVAEAFAKLHTHEHADGHSHDHVHDRH
CCCCCCCCHHHHEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GHHHGHGHGHEHDHHHHGDAHSLLFIENVGNLVCPAMWDLGEAAKVAILSVTEGEDKPLK
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEECHHHHCCCCCCEEEEEEEECCCCCCCC
YPDMFAASQLMILNKTDLLPHVKFDVARCIALARRVNPAIEVIQLSATTGEGMDAWLHWL
CCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHH
DHAMSTHHHHHDETVSEEAALRERVKQLEAELARAKAVLSAKTPI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MCVVCGCSDNSPTHARHVQQASGEPGVITVNPANGDLHFGAGVARVSVPGMSQERAIKLE
CEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEECCCEEEEECCCCCCCCEEEEE
TDILGANNRVAQQNRAHFELHGVTALNVVSSPGSGKTTLLCATIEALKARQPGLHVAVIE
EEEECCCCCHHHCCCCEEEEECEEEEEEECCCCCCCEEEEEEEHHHHHCCCCCCEEEEEE
GDQQTSFDADRIRATGAPAIQVNTGKGCHLDAPMVAEAFAKLHTHEHADGHSHDHVHDRH
CCCCCCCCHHHHEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GHHHGHGHGHEHDHHHHGDAHSLLFIENVGNLVCPAMWDLGEAAKVAILSVTEGEDKPLK
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEECHHHHCCCCCCEEEEEEEECCCCCCCC
YPDMFAASQLMILNKTDLLPHVKFDVARCIALARRVNPAIEVIQLSATTGEGMDAWLHWL
CCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHH
DHAMSTHHHHHDETVSEEAALRERVKQLEAELARAKAVLSAKTPI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8352644; 12948488 [H]