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The map label for this gene is hypA1 [H]

Identifier: 94310230

GI number: 94310230

Start: 1405890

End: 1406237

Strand: Reverse

Name: hypA1 [H]

Synonym: Rmet_1286

Alternate gene names: 94310230

Gene position: 1406237-1405890 (Counterclockwise)

Preceding gene: 94310231

Following gene: 94310229

Centisome position: 35.8

GC content: 62.93

Gene sequence:

>348_bases
ATGCATGAAGCGAGTCTGGCTGGCGGTGTGCTGCAGCTGGTGGAAGATACCGCACGGCGGGAAGGCTTTGCACGCCTGCT
CGAACTGCGGCTGGAAGCCGGCCAGCTGGCCGGTGTGGATGTTCGAGCCCTGCGCTTTGCGCTGGAGAGCATCGCACCCG
GTACCCTGATGGCTGGTGCACGCATCGAAATCGAGGAGCCGCCTGGTCAGGCATGGTGCCTGTCATGCAGCCAGACGGTA
GCCATCGCGCAACGCGGCGACGCCTGTCCTGCCTGCGGTGGCTACCAACTGCAGCCCACGGGCGGCATGGAATTGCGCAT
CATTGACATGAAAGTCAGTGATGATTGA

Upstream 100 bases:

>100_bases
CTTGCGGCCCGGGTGCGCCTGCTGATGGCAGCGCTGGATCCCTGCGTTCCTTTCGAGATCGCGGCGCCTTTGGTGCACGA
TGCGCCTCTGGAGGTCAACC

Downstream 100 bases:

>100_bases
AACCCGTTTGAAGGAGACCCAGCATGTGTGTCGTATGCGGATGCAGTGACAACAGCCCGACTCATGCGCGGCATGTGCAA
CAGGCCAGCGGTGAGCCCGG

Product: hydrogenase nickel incorporation protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MHEASLAGGVLQLVEDTARREGFARLLELRLEAGQLAGVDVRALRFALESIAPGTLMAGARIEIEEPPGQAWCLSCSQTV
AIAQRGDACPACGGYQLQPTGGMELRIIDMKVSDD

Sequences:

>Translated_115_residues
MHEASLAGGVLQLVEDTARREGFARLLELRLEAGQLAGVDVRALRFALESIAPGTLMAGARIEIEEPPGQAWCLSCSQTV
AIAQRGDACPACGGYQLQPTGGMELRIIDMKVSDD
>Mature_115_residues
MHEASLAGGVLQLVEDTARREGFARLLELRLEAGQLAGVDVRALRFALESIAPGTLMAGARIEIEEPPGQAWCLSCSQTV
AIAQRGDACPACGGYQLQPTGGMELRIIDMKVSDD

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=34.8214285714286, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=30.9734513274336, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 12211; Mature: 12211

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEASLAGGVLQLVEDTARREGFARLLELRLEAGQLAGVDVRALRFALESIAPGTLMAGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEECCC
RIEIEEPPGQAWCLSCSQTVAIAQRGDACPACGGYQLQPTGGMELRIIDMKVSDD
EEEEECCCCCEEEECCCCEEEEEECCCCCCCCCCEEECCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MHEASLAGGVLQLVEDTARREGFARLLELRLEAGQLAGVDVRALRFALESIAPGTLMAGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEECCC
RIEIEEPPGQAWCLSCSQTVAIAQRGDACPACGGYQLQPTGGMELRIIDMKVSDD
EEEEECCCCCEEEECCCCEEEEEECCCCCCCCCCEEECCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA