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The map label for this gene is tas [H]

Identifier: 94310157

GI number: 94310157

Start: 1331147

End: 1332205

Strand: Reverse

Name: tas [H]

Synonym: Rmet_1212

Alternate gene names: 94310157

Gene position: 1332205-1331147 (Counterclockwise)

Preceding gene: 94310158

Following gene: 94310156

Centisome position: 33.91

GC content: 64.68

Gene sequence:

>1059_bases
ATGAAAATGATCCGACTCGGCCGCAGCGACCTCGAAGTCTCGCGCATCTGCCTCGGCACGATGACCTTCGGCGAGCAGAA
CACCGAGGCCGAGGGCCATAGCCAGCTTGACTACGCATTCTCGCGCGGCATCAATTTCATCGACACCGCCGAGATGTACC
CGGTCAAGCCGCGCGCCGAGACGTACGGCAGCACCGAGCGCATCATCGGCACCTGGCTGAAGAAGCAGCCGCGCGATCGC
GTCGTGCTCGCCAGCAAGGTGGCCGGCCCGGCGCGCAACCCGTGGATACGCAATGGCGGGGATCTGACGCCTGACAGCAT
CCGCGCCGCGGTCGAGGATTCCCTCAAGCGGCTGCAGACCGACTACATCGACCTCTACCAGATTCATTGGCCGGCGCGTA
ACGCGCCGATTTTCGGCCAGAAGCGCTTCAACCCCGAAGCTGAGCGCCAGTGCGCGACAATCGAGGCGCAACTCGAAGCG
ATGGGCGATCTGGTGCGGGCCGGCAAGATCCGCTACGTCGGCGTGTCGAACGAAACGCCGTGGGGCGTGACGGAGTTCGT
CAATGTGGCCGAGCGGCATGGCCTGCCCCGCATCGCCACGATCCAGAACCCGTACAACCTCGTCAACCGCAGCTTCGAGC
AGGGGCTGGACGAGACCTGCTTCCGCACCGAGGTCAGCCTGCTGGCGTACAGCCCGCTCGGGTTCGGCCAGTTGACCGGC
AAATACCTGACCGGTGATGCAAACCACCCCGTATTCAACCCGGACGCCGTTGGCCGGCTGACGCGCTTCTCCCCTGACTG
GAGCCCGCGCTACATGCGAGCCGAGACGATGGCGGCCGCCGCGCGGTACCTGGAACTCGCCCGCGCGCACGGGATGTCGG
GCGCCACATTGGCGCTCGCATGGTGCTATTCGCGCTGGTTTATCGCCAGCACGATCATCGGCGCCACGGGCCTTGCGCAA
CTTAAAGAAAACGTAGACGCCCTGGATACCGCACTTTCGGCCGAGGTGCTGTCGGCCGTTGAGCGCATTCACGCCGAAAT
CCACAATCCGGCGCAATAA

Upstream 100 bases:

>100_bases
GATCTATCGCGGGCCGACGCTGGTGCGCGAATGCGCCAGCGCCCTGCGCCGATAGCGCTTTTCAGGCATTCTGTCGGCCG
ACACGATCCAGGGAAACACC

Downstream 100 bases:

>100_bases
TTTGCGGTGCACCTCCCCAGTAGAGGTGTTTTTCAGCAGGATATGGCGCGGTGCGGCATTAAAAGCGAGCCATCCAGGCG
GTGAAAATGGTATGCTGCGA

Product: putative oxidoreductase, NADP(H)-dependent aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKMIRLGRSDLEVSRICLGTMTFGEQNTEAEGHSQLDYAFSRGINFIDTAEMYPVKPRAETYGSTERIIGTWLKKQPRDR
VVLASKVAGPARNPWIRNGGDLTPDSIRAAVEDSLKRLQTDYIDLYQIHWPARNAPIFGQKRFNPEAERQCATIEAQLEA
MGDLVRAGKIRYVGVSNETPWGVTEFVNVAERHGLPRIATIQNPYNLVNRSFEQGLDETCFRTEVSLLAYSPLGFGQLTG
KYLTGDANHPVFNPDAVGRLTRFSPDWSPRYMRAETMAAAARYLELARAHGMSGATLALAWCYSRWFIASTIIGATGLAQ
LKENVDALDTALSAEVLSAVERIHAEIHNPAQ

Sequences:

>Translated_352_residues
MKMIRLGRSDLEVSRICLGTMTFGEQNTEAEGHSQLDYAFSRGINFIDTAEMYPVKPRAETYGSTERIIGTWLKKQPRDR
VVLASKVAGPARNPWIRNGGDLTPDSIRAAVEDSLKRLQTDYIDLYQIHWPARNAPIFGQKRFNPEAERQCATIEAQLEA
MGDLVRAGKIRYVGVSNETPWGVTEFVNVAERHGLPRIATIQNPYNLVNRSFEQGLDETCFRTEVSLLAYSPLGFGQLTG
KYLTGDANHPVFNPDAVGRLTRFSPDWSPRYMRAETMAAAARYLELARAHGMSGATLALAWCYSRWFIASTIIGATGLAQ
LKENVDALDTALSAEVLSAVERIHAEIHNPAQ
>Mature_352_residues
MKMIRLGRSDLEVSRICLGTMTFGEQNTEAEGHSQLDYAFSRGINFIDTAEMYPVKPRAETYGSTERIIGTWLKKQPRDR
VVLASKVAGPARNPWIRNGGDLTPDSIRAAVEDSLKRLQTDYIDLYQIHWPARNAPIFGQKRFNPEAERQCATIEAQLEA
MGDLVRAGKIRYVGVSNETPWGVTEFVNVAERHGLPRIATIQNPYNLVNRSFEQGLDETCFRTEVSLLAYSPLGFGQLTG
KYLTGDANHPVFNPDAVGRLTRFSPDWSPRYMRAETMAAAARYLELARAHGMSGATLALAWCYSRWFIASTIIGATGLAQ
LKENVDALDTALSAEVLSAVERIHAEIHNPAQ

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=348, Percent_Identity=27.2988505747126, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4504825, Length=348, Percent_Identity=27.2988505747126, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI223718702, Length=328, Percent_Identity=30.1829268292683, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI41327764, Length=327, Percent_Identity=28.7461773700306, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI27436964, Length=353, Percent_Identity=26.0623229461756, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436962, Length=348, Percent_Identity=25.8620689655172, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI27436966, Length=348, Percent_Identity=25.8620689655172, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41152114, Length=244, Percent_Identity=29.5081967213115, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI27436971, Length=341, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI223718708, Length=180, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1789199, Length=358, Percent_Identity=48.8826815642458, Blast_Score=327, Evalue=5e-91,
Organism=Escherichia coli, GI87081735, Length=354, Percent_Identity=32.2033898305085, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788070, Length=357, Percent_Identity=32.2128851540616, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789375, Length=344, Percent_Identity=28.7790697674419, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788081, Length=347, Percent_Identity=27.9538904899135, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=328, Percent_Identity=25.3048780487805, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325169, Length=368, Percent_Identity=25, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6323998, Length=347, Percent_Identity=24.7838616714697, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=275, Percent_Identity=24.3636363636364, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=349, Percent_Identity=23.2091690544413, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24646159, Length=341, Percent_Identity=27.8592375366569, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39193; Mature: 39193

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMIRLGRSDLEVSRICLGTMTFGEQNTEAEGHSQLDYAFSRGINFIDTAEMYPVKPRAE
CCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCCCCCCHH
TYGSTERIIGTWLKKQPRDRVVLASKVAGPARNPWIRNGGDLTPDSIRAAVEDSLKRLQT
HCCCHHHHHHHHHHCCCCCCEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DYIDLYQIHWPARNAPIFGQKRFNPEAERQCATIEAQLEAMGDLVRAGKIRYVGVSNETP
HHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
WGVTEFVNVAERHGLPRIATIQNPYNLVNRSFEQGLDETCFRTEVSLLAYSPLGFGQLTG
CCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHEECCCCCHHHCC
KYLTGDANHPVFNPDAVGRLTRFSPDWSPRYMRAETMAAAARYLELARAHGMSGATLALA
CEEECCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
WCYSRWFIASTIIGATGLAQLKENVDALDTALSAEVLSAVERIHAEIHNPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKMIRLGRSDLEVSRICLGTMTFGEQNTEAEGHSQLDYAFSRGINFIDTAEMYPVKPRAE
CCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCCCCCCHH
TYGSTERIIGTWLKKQPRDRVVLASKVAGPARNPWIRNGGDLTPDSIRAAVEDSLKRLQT
HCCCHHHHHHHHHHCCCCCCEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DYIDLYQIHWPARNAPIFGQKRFNPEAERQCATIEAQLEAMGDLVRAGKIRYVGVSNETP
HHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
WGVTEFVNVAERHGLPRIATIQNPYNLVNRSFEQGLDETCFRTEVSLLAYSPLGFGQLTG
CCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHEECCCCCHHHCC
KYLTGDANHPVFNPDAVGRLTRFSPDWSPRYMRAETMAAAARYLELARAHGMSGATLALA
CEEECCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
WCYSRWFIASTIIGATGLAQLKENVDALDTALSAEVLSAVERIHAEIHNPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]