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The map label for this gene is dctS [H]

Identifier: 94310140

GI number: 94310140

Start: 1309429

End: 1312041

Strand: Reverse

Name: dctS [H]

Synonym: Rmet_1195

Alternate gene names: 94310140

Gene position: 1312041-1309429 (Counterclockwise)

Preceding gene: 94310145

Following gene: 94310139

Centisome position: 33.4

GC content: 66.05

Gene sequence:

>2613_bases
ATGCAGTTTCTCAAACGAATTCTCTCCGGCCTGCGCACGGCCATTCTGCCTCCGAACCCTGCCGGCGCCGTCAGCGATGC
CCCTCACGGGGTAGTCCATGCCGACCGTAGCAACGGTGCCAACGCTCATGGCACCCCCCAGGTCGAGGCACAAGACAGCA
CCGATGGCACGGACGGCGGCACGCCGCTGGCCGCCGCCCCCCGCCGCCTCTGGATCACGCGCTGGCGCAATCTCGTCGCT
ACGAGCTGGTTCATGTTCATCCCGCTCGTGGCCATCGTGCTGTTCACGGTAGCGATGGGCGTCATCCTCTGGTCGCTCCA
CGAAACCGAGCACCAGCAGCAGCGCGACGCGCTGTACCGCGACGCCGCCTGGGCGCAGCAGCGCGTGCGCCTGTCCCTGC
TGAGCAACCAGGACCAGTTGGCCTCGCTGGCGCGGGATATCGCGGCCGCGCAGCTCGACCAGGGCGCCTACCGGACGGCC
GCACAGGAAATCCTGCGCGAGAACCCGGAGATCGTCTTCATCAACTGGCTCGACGCCACGCGGCGCGGCCGCTGGTCGCT
GCCATCGACGTCGGAATTCGCCGCCCGCCTGCGCGAAACCGCCGATCAGCCGCTCGAGCCCGAGGTCCTGGACACGTTCG
ACGCCGCGCGCGAGACCCAGCGTGTGGTCTATTCCCGGCCGCTGATGAACGATCGCGGCGACAGCTTCATGCTGATGGAA
GTGCCGATCGTGCGCGATAACGAGTTCCTGGGCACGCTGGGCGCGCTCTACTCGATCAACGGCATCCTGACGCACCTGCT
GCCACCGGAACTGACCGAGCGTTACCGCTTCTCGCTGATCGACAAGAACAACCAGACCCGGGCCAGCACCTCGGTACGGC
CGGTACCGGGCAATGCGCTGTCCTACGAGGTCCTGCTCGACCCGCCGGGCCATTCGCTGTCCCTGCGCGCCGACGCCTAC
CCACCGCCCTCGAACCTGCCCAACAACATGTTGCTGTGGCTGGTGGTGGGCCTGTCGTGCTTCCTGCTGTGGAGTCTGTG
GAGCATGTGGCGCCATACCAGCCGCCGCTCCGAAGCCCAGCGCGCCCTGCTGGCCGAAACCTCGTTCCGTCGCGCGATGG
AAAACTCGATGCTGATCGGGCTGCGGGCACTGGACCTGAACGGGCGAATCACCTACGTGAATCCCGCGTTCTGCCGCATG
ACCGGCTGGACCGAGAACGATCTGGTCGGCCGCGTGCCGCCCTTCCCGTACTGGCCGCCCAATGACCAGCAGGAGATGCA
GAAGCAGATCGACCTGACGCTGCAGGGCAAGTCGCCGGCCACCGGCTATGAAATGCGCGTCATGCGCCGTGACGGCAGCA
GCTTCTTCGCCCGCATGTACGTATCGCCGCTGGTAGACGGCCGTGGCCGCCATACGGGCTGGATGAGCTCGATGACGGAC
ATCACCGAGCCGAAGCGCGCCCGCGAGGAACTCGCCGCCGCGCACGACCGCTTCACGACGGTGCTGGAAAGCCTGGACGC
GGCTGTATCTGTGCTGGCCACGGACAAGGCCGAGTTGCTGTTCGCCAACCGCTACTATCGGCAGCTCTTCGGCTGGGAAG
CCGAGGGCCACCTGAAGCTGGCCGGGGACGACTTCGACAAGGACCAGATGTCGAGCGACAACACCGACTTCGTCGATGCC
TATGCCGGCCTGCCCGCCTCGGAACTGATGCCGTACGCGTCCGACGCCCGCGAGGTGTTCGTGCCGGACATGCAGAAATG
GTTTGAAGTGCGCCGCCGCTATATCCAGTGGGTGGACGGCCACCTCGCGCAGATGCAGATCGCCACCGACATCACGGTGC
GCAAGGCAGCCGAGGAAATGGCGCGCCAGCACGAGGAACGCCTGCAGTTCACGAGCCGCCTGACCACAATGGGCGAGATG
GCGTCGTCGCTGGCGCACGAGCTGAACCAGCCGCTGGCGGCCATCAACAACTACTGCATGGGCGCCGTGGCTCGCCTGCA
TTCGGGCCGGAGCACGCCGGAAGACCTGATCCCGGTGCTGGAAAAGACCTCGGCACAGGCAGTGCGCGCGGGCACGATCA
TCAGCCGCATTCGCGGTTTCGTGAAGCGTAGCCAGCCGCAGCGGCGCGAAGCCTCGCTGCACGACATCGTGGCCGATGCC
GTCGGCCTGGCCGACCTGGAGGCCGCGCGGCGCCGCGTCACGATCCTGACCCGCCTGCCGACCCCGCCGCTGATGCTCTA
CGTGGACCCGGTGCTGATCGAGCAGGTACTGGTCAACCTGCTCAAGAATGCCGTGGAAGCGATGGCCGGCATGCCGGCCC
TGCGCGCCGCGGGCGTGGTACGGTTGCACGCGCGCGTAGAAAACGTCGAATTTGGCCAGAGCGTCTGTATCGACGTGATC
GACCAGGGCCCCGGCGTGGACGAAGCCACCAAGGAGCGCCTGTTCGAGCCGTTCTTCAGCACCAAAGCGGACGGCATGGG
CATGGGCCTGAATATCTGCCGTTCGATCATCGAATCCCATCAAGGCCGTCTGTGGGTAGAAAACAATGTGGACGGCATCG
GCTGTACGTTTAAAATCACCCTGCCGCTGCAGCCTGCGCTACCCGAACAGTAA

Upstream 100 bases:

>100_bases
CCTCGCGACCAGCGCGCAAATACTGTGCCGTGTAGGCGCTTTCCCCAAGCGACGCACCGCAATAAAGTGGATAAACTGCT
CGGTCAGCCGTCAATCCCCT

Downstream 100 bases:

>100_bases
CGGGGATGCCCTCGGGCGAAGCGGACGACCCTCTGCCGCGGGGCATCGGGAGGTCGTCCGGATCGTTCACCCGGGGTGTT
GCGCACTGCCGCTGGCGGTT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 870; Mature: 870

Protein sequence:

>870_residues
MQFLKRILSGLRTAILPPNPAGAVSDAPHGVVHADRSNGANAHGTPQVEAQDSTDGTDGGTPLAAAPRRLWITRWRNLVA
TSWFMFIPLVAIVLFTVAMGVILWSLHETEHQQQRDALYRDAAWAQQRVRLSLLSNQDQLASLARDIAAAQLDQGAYRTA
AQEILRENPEIVFINWLDATRRGRWSLPSTSEFAARLRETADQPLEPEVLDTFDAARETQRVVYSRPLMNDRGDSFMLME
VPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSVRPVPGNALSYEVLLDPPGHSLSLRADAY
PPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEAQRALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCRM
TGWTENDLVGRVPPFPYWPPNDQQEMQKQIDLTLQGKSPATGYEMRVMRRDGSSFFARMYVSPLVDGRGRHTGWMSSMTD
ITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLKLAGDDFDKDQMSSDNTDFVDA
YAGLPASELMPYASDAREVFVPDMQKWFEVRRRYIQWVDGHLAQMQIATDITVRKAAEEMARQHEERLQFTSRLTTMGEM
ASSLAHELNQPLAAINNYCMGAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVADA
VGLADLEAARRRVTILTRLPTPPLMLYVDPVLIEQVLVNLLKNAVEAMAGMPALRAAGVVRLHARVENVEFGQSVCIDVI
DQGPGVDEATKERLFEPFFSTKADGMGMGLNICRSIIESHQGRLWVENNVDGIGCTFKITLPLQPALPEQ

Sequences:

>Translated_870_residues
MQFLKRILSGLRTAILPPNPAGAVSDAPHGVVHADRSNGANAHGTPQVEAQDSTDGTDGGTPLAAAPRRLWITRWRNLVA
TSWFMFIPLVAIVLFTVAMGVILWSLHETEHQQQRDALYRDAAWAQQRVRLSLLSNQDQLASLARDIAAAQLDQGAYRTA
AQEILRENPEIVFINWLDATRRGRWSLPSTSEFAARLRETADQPLEPEVLDTFDAARETQRVVYSRPLMNDRGDSFMLME
VPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSVRPVPGNALSYEVLLDPPGHSLSLRADAY
PPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEAQRALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCRM
TGWTENDLVGRVPPFPYWPPNDQQEMQKQIDLTLQGKSPATGYEMRVMRRDGSSFFARMYVSPLVDGRGRHTGWMSSMTD
ITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLKLAGDDFDKDQMSSDNTDFVDA
YAGLPASELMPYASDAREVFVPDMQKWFEVRRRYIQWVDGHLAQMQIATDITVRKAAEEMARQHEERLQFTSRLTTMGEM
ASSLAHELNQPLAAINNYCMGAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVADA
VGLADLEAARRRVTILTRLPTPPLMLYVDPVLIEQVLVNLLKNAVEAMAGMPALRAAGVVRLHARVENVEFGQSVCIDVI
DQGPGVDEATKERLFEPFFSTKADGMGMGLNICRSIIESHQGRLWVENNVDGIGCTFKITLPLQPALPEQ
>Mature_870_residues
MQFLKRILSGLRTAILPPNPAGAVSDAPHGVVHADRSNGANAHGTPQVEAQDSTDGTDGGTPLAAAPRRLWITRWRNLVA
TSWFMFIPLVAIVLFTVAMGVILWSLHETEHQQQRDALYRDAAWAQQRVRLSLLSNQDQLASLARDIAAAQLDQGAYRTA
AQEILRENPEIVFINWLDATRRGRWSLPSTSEFAARLRETADQPLEPEVLDTFDAARETQRVVYSRPLMNDRGDSFMLME
VPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSVRPVPGNALSYEVLLDPPGHSLSLRADAY
PPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEAQRALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCRM
TGWTENDLVGRVPPFPYWPPNDQQEMQKQIDLTLQGKSPATGYEMRVMRRDGSSFFARMYVSPLVDGRGRHTGWMSSMTD
ITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLKLAGDDFDKDQMSSDNTDFVDA
YAGLPASELMPYASDAREVFVPDMQKWFEVRRRYIQWVDGHLAQMQIATDITVRKAAEEMARQHEERLQFTSRLTTMGEM
ASSLAHELNQPLAAINNYCMGAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVADA
VGLADLEAARRRVTILTRLPTPPLMLYVDPVLIEQVLVNLLKNAVEAMAGMPALRAAGVVRLHARVENVEFGQSVCIDVI
DQGPGVDEATKERLFEPFFSTKADGMGMGLNICRSIIESHQGRLWVENNVDGIGCTFKITLPLQPALPEQ

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=367, Percent_Identity=26.158038147139, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=28.3333333333333, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1786912, Length=427, Percent_Identity=26.9320843091335, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=233, Percent_Identity=29.6137339055794, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI145693157, Length=278, Percent_Identity=26.6187050359712, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=26.9387755102041, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788713, Length=237, Percent_Identity=24.0506329113924, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 97448; Mature: 97448

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFLKRILSGLRTAILPPNPAGAVSDAPHGVVHADRSNGANAHGTPQVEAQDSTDGTDGG
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
TPLAAAPRRLWITRWRNLVATSWFMFIPLVAIVLFTVAMGVILWSLHETEHQQQRDALYR
CCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAWAQQRVRLSLLSNQDQLASLARDIAAAQLDQGAYRTAAQEILRENPEIVFINWLDAT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCC
RRGRWSLPSTSEFAARLRETADQPLEPEVLDTFDAARETQRVVYSRPLMNDRGDSFMLME
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSVRPVPGNAL
ECEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCE
SYEVLLDPPGHSLSLRADAYPPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEAQ
EEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCRMTGWTENDLVGRVPPFPYWPP
HHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEECHHHHEECCCCCCCCCCCCCCCCCCCC
NDQQEMQKQIDLTLQGKSPATGYEMRVMRRDGSSFFARMYVSPLVDGRGRHTGWMSSMTD
CCHHHHHHHCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEE
AGDDFDKDQMSSDNTDFVDAYAGLPASELMPYASDAREVFVPDMQKWFEVRRRYIQWVDG
CCCCCCHHHCCCCCCCHHHHHCCCCHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCC
HLAQMQIATDITVRKAAEEMARQHEERLQFTSRLTTMGEMASSLAHELNQPLAAINNYCM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVADA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VGLADLEAARRRVTILTRLPTPPLMLYVDPVLIEQVLVNLLKNAVEAMAGMPALRAAGVV
HHHHHHHHHHHHEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHH
RLHARVENVEFGQSVCIDVIDQGPGVDEATKERLFEPFFSTKADGMGMGLNICRSIIESH
EEEHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
QGRLWVENNVDGIGCTFKITLPLQPALPEQ
CCCEEEECCCCCEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MQFLKRILSGLRTAILPPNPAGAVSDAPHGVVHADRSNGANAHGTPQVEAQDSTDGTDGG
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
TPLAAAPRRLWITRWRNLVATSWFMFIPLVAIVLFTVAMGVILWSLHETEHQQQRDALYR
CCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAWAQQRVRLSLLSNQDQLASLARDIAAAQLDQGAYRTAAQEILRENPEIVFINWLDAT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCC
RRGRWSLPSTSEFAARLRETADQPLEPEVLDTFDAARETQRVVYSRPLMNDRGDSFMLME
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSVRPVPGNAL
ECEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCE
SYEVLLDPPGHSLSLRADAYPPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEAQ
EEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCRMTGWTENDLVGRVPPFPYWPP
HHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEECHHHHEECCCCCCCCCCCCCCCCCCCC
NDQQEMQKQIDLTLQGKSPATGYEMRVMRRDGSSFFARMYVSPLVDGRGRHTGWMSSMTD
CCHHHHHHHCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEE
AGDDFDKDQMSSDNTDFVDAYAGLPASELMPYASDAREVFVPDMQKWFEVRRRYIQWVDG
CCCCCCHHHCCCCCCCHHHHHCCCCHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCC
HLAQMQIATDITVRKAAEEMARQHEERLQFTSRLTTMGEMASSLAHELNQPLAAINNYCM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVADA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VGLADLEAARRRVTILTRLPTPPLMLYVDPVLIEQVLVNLLKNAVEAMAGMPALRAAGVV
HHHHHHHHHHHHEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHH
RLHARVENVEFGQSVCIDVIDQGPGVDEATKERLFEPFFSTKADGMGMGLNICRSIIESH
EEEHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
QGRLWVENNVDGIGCTFKITLPLQPALPEQ
CCCEEEECCCCCEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]