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The map label for this gene is gltC [H]

Identifier: 94310130

GI number: 94310130

Start: 1298144

End: 1299076

Strand: Direct

Name: gltC [H]

Synonym: Rmet_1185

Alternate gene names: 94310130

Gene position: 1298144-1299076 (Clockwise)

Preceding gene: 94310125

Following gene: 94310131

Centisome position: 33.05

GC content: 69.24

Gene sequence:

>933_bases
ATGCGCCCACTGTCTCAATGGCTCCCATCCGTCATGCACGCCCGTGTCCTGCGCTATCTCGATGAAGTCGTGCGCCGTGG
TTCGATCCGTCGCGCCGCCGAGCATCTGCACGTGGCGCCAACTGCGATCAACCGGCAGATCCTTGAGTTGGAGGCGGAGT
TGGGGGCACCGCTGTTCGACCGGATCAACCGCCGCCTGCACCTGACGCCGTTGGGTGAGATGGTGCTCGCTCACGTGCGG
CAGACGCTGCGCGAGCATGAGGCGCTGCAGGCGCGCGTTGCCGAGATCAAGGGCGCGCGGCGCGGCATGGTCACGGTTGC
GACCACGTCGGGTCTGGCGGGCTCCCTGCTGCCATCTCTCGTGCACGACTTCCGCCAGCATCACCCTGGCATCGTGGTGC
GTGTGGCGGACCTGCCCGTGGCCGGCATCGTGGCGGCGGTGGAGCAGGGCGACGCAGACCTGGGGCTCGGCTACGACTTG
CCGGAGGTGGCGGCGTTCCGCGTGATGGCCAGCCGTGACTGGTCGATTGGCGCGGTGGTGGCGCCGGGGCATCCCCTGGC
CACGCAGCCGTCGACACGGCTGGCGGAGTGCGCCGGCTATCCATTGATCCTCCCGGCGCCTTCGCTGTCGATCCGCGCGC
TCGTCGACGACGCCTTCGCGCGCCAGTCGGTCGAGGTGACGTCCGCTGTGGAATCGACCTCGGTCGTGTTGATCCAGCGA
CTCGCGGCGGCCGGGGCCGGTGTGGCGCTGCTCAATCCGCTCGATGTGATGGATGAGCGCGCGCGTGGCGCCGTGGTCTT
CGTGCCGCTGCGCGACAGCGATCTACGGCAGCAAGCGTTGAGGATGGTTGCGCGGGCGCGGGCGCCGCTGAGTCCCGCAG
CCGAACTGATGGCGGAGCGTATCGGCACCGCGCTGGACGGCCTGTTCCGTTAA

Upstream 100 bases:

>100_bases
AGCTAACGCCCCAACGAAGAAAGAGATTCTAGCAAGGTACCGAATACTGCGCAAGCCCTTGTTCGCAATTTTTTCATCGG
CATGTCAGGTGCCGCTTACA

Downstream 100 bases:

>100_bases
TTCCGCCCGTCAACGGTTCACGATCCAGGTGTCCTCATTTTGTGGACACCAAGCGCGAAATTCTGCGCTTTGGGTGCGTA
CTGGCGTTGCGTAGACTGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MRPLSQWLPSVMHARVLRYLDEVVRRGSIRRAAEHLHVAPTAINRQILELEAELGAPLFDRINRRLHLTPLGEMVLAHVR
QTLREHEALQARVAEIKGARRGMVTVATTSGLAGSLLPSLVHDFRQHHPGIVVRVADLPVAGIVAAVEQGDADLGLGYDL
PEVAAFRVMASRDWSIGAVVAPGHPLATQPSTRLAECAGYPLILPAPSLSIRALVDDAFARQSVEVTSAVESTSVVLIQR
LAAAGAGVALLNPLDVMDERARGAVVFVPLRDSDLRQQALRMVARARAPLSPAAELMAERIGTALDGLFR

Sequences:

>Translated_310_residues
MRPLSQWLPSVMHARVLRYLDEVVRRGSIRRAAEHLHVAPTAINRQILELEAELGAPLFDRINRRLHLTPLGEMVLAHVR
QTLREHEALQARVAEIKGARRGMVTVATTSGLAGSLLPSLVHDFRQHHPGIVVRVADLPVAGIVAAVEQGDADLGLGYDL
PEVAAFRVMASRDWSIGAVVAPGHPLATQPSTRLAECAGYPLILPAPSLSIRALVDDAFARQSVEVTSAVESTSVVLIQR
LAAAGAGVALLNPLDVMDERARGAVVFVPLRDSDLRQQALRMVARARAPLSPAAELMAERIGTALDGLFR
>Mature_310_residues
MRPLSQWLPSVMHARVLRYLDEVVRRGSIRRAAEHLHVAPTAINRQILELEAELGAPLFDRINRRLHLTPLGEMVLAHVR
QTLREHEALQARVAEIKGARRGMVTVATTSGLAGSLLPSLVHDFRQHHPGIVVRVADLPVAGIVAAVEQGDADLGLGYDL
PEVAAFRVMASRDWSIGAVVAPGHPLATQPSTRLAECAGYPLILPAPSLSIRALVDDAFARQSVEVTSAVESTSVVLIQR
LAAAGAGVALLNPLDVMDERARGAVVFVPLRDSDLRQQALRMVARARAPLSPAAELMAERIGTALDGLFR

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=298, Percent_Identity=25.8389261744966, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787530, Length=248, Percent_Identity=27.4193548387097, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI157672245, Length=227, Percent_Identity=27.3127753303965, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787601, Length=230, Percent_Identity=26.9565217391304, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693105, Length=282, Percent_Identity=26.241134751773, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789204, Length=252, Percent_Identity=25.3968253968254, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788297, Length=244, Percent_Identity=29.0983606557377, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082132, Length=259, Percent_Identity=25.0965250965251, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788887, Length=265, Percent_Identity=27.1698113207547, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=26.0162601626016, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787949, Length=175, Percent_Identity=29.7142857142857, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787879, Length=246, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=294, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786401, Length=251, Percent_Identity=26.6932270916335, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082024, Length=176, Percent_Identity=27.8409090909091, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788748, Length=281, Percent_Identity=23.8434163701068, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790208, Length=246, Percent_Identity=27.6422764227642, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789506, Length=266, Percent_Identity=19.5488721804511, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33431; Mature: 33431

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLSQWLPSVMHARVLRYLDEVVRRGSIRRAAEHLHVAPTAINRQILELEAELGAPLFD
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHH
RINRRLHLTPLGEMVLAHVRQTLREHEALQARVAEIKGARRGMVTVATTSGLAGSLLPSL
HCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
VHDFRQHHPGIVVRVADLPVAGIVAAVEQGDADLGLGYDLPEVAAFRVMASRDWSIGAVV
HHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
APGHPLATQPSTRLAECAGYPLILPAPSLSIRALVDDAFARQSVEVTSAVESTSVVLIQR
CCCCCCCCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAAGAGVALLNPLDVMDERARGAVVFVPLRDSDLRQQALRMVARARAPLSPAAELMAER
HHHCCCCCHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
IGTALDGLFR
HHHHHHHHCC
>Mature Secondary Structure
MRPLSQWLPSVMHARVLRYLDEVVRRGSIRRAAEHLHVAPTAINRQILELEAELGAPLFD
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHH
RINRRLHLTPLGEMVLAHVRQTLREHEALQARVAEIKGARRGMVTVATTSGLAGSLLPSL
HCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
VHDFRQHHPGIVVRVADLPVAGIVAAVEQGDADLGLGYDLPEVAAFRVMASRDWSIGAVV
HHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
APGHPLATQPSTRLAECAGYPLILPAPSLSIRALVDDAFARQSVEVTSAVESTSVVLIQR
CCCCCCCCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAAGAGVALLNPLDVMDERARGAVVFVPLRDSDLRQQALRMVARARAPLSPAAELMAER
HHHCCCCCHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
IGTALDGLFR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]