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The map label for this gene is atzB [H]

Identifier: 94310131

GI number: 94310131

Start: 1299192

End: 1300595

Strand: Direct

Name: atzB [H]

Synonym: Rmet_1186

Alternate gene names: 94310131

Gene position: 1299192-1300595 (Clockwise)

Preceding gene: 94310130

Following gene: 94310132

Centisome position: 33.07

GC content: 65.95

Gene sequence:

>1404_bases
ATGCACATCACTATGACTTTGATCCTTCAGCACGCCGACGTACTCGTCACCATGGACGCGCAGCGGCGCGAAATTGCCGA
TGGCGCGCTGGTCGCGAACGGGCCGGCGGTGGAGTGGGTGGGGCCCACGGCCGAGTTGCCCGAGCAATACCGTCGGCTTG
TCGACGAGGGGCGCGCCGAGGTTGTCGATATGCGCGGGCATGTGGTCATGCCCGGGCTGGTCAACACCCATCACCATATG
TACCAGAGCCTGACGCGCGCCGTGCCTGCCGCGCAGGATGCCGAGTTGTTCGGGTGGCTGACCAATCTCTACATGCTCTG
GTCGCACCTGACGCCGGAGATGATCCGCGTGTCGACCCAGACCGCGATGGCCGAACTGATGCTGTCCGGATGCACGACTA
CCAGCGATCACCTGTACCTCTATCCAAATGGATCGCGCCTGGACGATTCGATCGACGCGGCGCGCCAGATCGGCATGCGT
TTTCACGCGGCACGCGGTTCGATGAGTGTCGGCCGTAGCCAGGGTGGCCTGCCGCCCGATGTCGTCGTGGAAACCGAGGC
AGCGATCTTGCGCGACAGCCAGCGGCTGGTCGAGCAGTATCACGATGCGTCGCGGCACGCGATGCTGCGTGTGGTGCTGG
CCCCGTGCTCGCCGTTCTCAGTGTCGCGCGACCTGATGAGGGAGTCCGCGAAGATGGCGCGCCACTACGGGGTGTCGCTG
CATACTCACCTTGCGGAGAACGACAACGACATTGCCTACTCGCGCGAGAAATTCGGCATGACGCCCGCGCAGTACGCGGA
GGATCTGGGCTGGGTTGGGCACGATGTCTGGCACGCGCACTGCGTGAAGCTCGATGAGGAAGGGGTGGCGTTGTTCGCCC
GTACCGGCACGGGCGTGGCGCATTGCCCTTGTTCCAACATGCGGCTGGCTTCTGGCATCGCGCCGATTCGCCGGATGCGT
GACGCCGGCGTGCCCGTGGGGCTCGGCGTCGGCGGCAGCGCATCGAACGACGGCGCGCACATGCTTGGCGAAGCCCGTCA
GGCGATGCTGCTGCAGCGGGTCGGGTACGGCCCGGCCGCGATGAGCGCGCGCGAGGCGCTCGAGATTGCCACGCTTGGCG
GGGCCAAGGTGCTGAATCGGGATGACATTGGCGCGCTCGCGCCGGGTATGTCGGCGGATATCGTCGCCTTCGATATGTCG
GGCGTCGGCTACGCTGGAGCTGGGCACGATCCGGTGGCGGCCCTGGTGTTCTGCACGCCGGGCAATGTGTCGATGAGCGT
TATCAATGGCCGCGTGGTGATTCGCGATGGACATCTGCTGACCGCGGATCTGCCGAACGTGCTGTCGGATCATCGGCGCC
TGGCGCGCACGCTGTTCGAGCGTGCGCAGGCGGCGGGTGCATGA

Upstream 100 bases:

>100_bases
GTTCACGATCCAGGTGTCCTCATTTTGTGGACACCAAGCGCGAAATTCTGCGCTTTGGGTGCGTACTGGCGTTGCGTAGA
CTGCGCAACGTTCACAACCG

Downstream 100 bases:

>100_bases
TTCGTTGAAAGCGCTCGGCGTTTGATGAGCGGATGACATCAAACGCCGGTCGATGCCGGAGCTGGTGTGCAGCGATGGCG
CATGCGCTGGATGACACTGG

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MHITMTLILQHADVLVTMDAQRREIADGALVANGPAVEWVGPTAELPEQYRRLVDEGRAEVVDMRGHVVMPGLVNTHHHM
YQSLTRAVPAAQDAELFGWLTNLYMLWSHLTPEMIRVSTQTAMAELMLSGCTTTSDHLYLYPNGSRLDDSIDAARQIGMR
FHAARGSMSVGRSQGGLPPDVVVETEAAILRDSQRLVEQYHDASRHAMLRVVLAPCSPFSVSRDLMRESAKMARHYGVSL
HTHLAENDNDIAYSREKFGMTPAQYAEDLGWVGHDVWHAHCVKLDEEGVALFARTGTGVAHCPCSNMRLASGIAPIRRMR
DAGVPVGLGVGGSASNDGAHMLGEARQAMLLQRVGYGPAAMSAREALEIATLGGAKVLNRDDIGALAPGMSADIVAFDMS
GVGYAGAGHDPVAALVFCTPGNVSMSVINGRVVIRDGHLLTADLPNVLSDHRRLARTLFERAQAAGA

Sequences:

>Translated_467_residues
MHITMTLILQHADVLVTMDAQRREIADGALVANGPAVEWVGPTAELPEQYRRLVDEGRAEVVDMRGHVVMPGLVNTHHHM
YQSLTRAVPAAQDAELFGWLTNLYMLWSHLTPEMIRVSTQTAMAELMLSGCTTTSDHLYLYPNGSRLDDSIDAARQIGMR
FHAARGSMSVGRSQGGLPPDVVVETEAAILRDSQRLVEQYHDASRHAMLRVVLAPCSPFSVSRDLMRESAKMARHYGVSL
HTHLAENDNDIAYSREKFGMTPAQYAEDLGWVGHDVWHAHCVKLDEEGVALFARTGTGVAHCPCSNMRLASGIAPIRRMR
DAGVPVGLGVGGSASNDGAHMLGEARQAMLLQRVGYGPAAMSAREALEIATLGGAKVLNRDDIGALAPGMSADIVAFDMS
GVGYAGAGHDPVAALVFCTPGNVSMSVINGRVVIRDGHLLTADLPNVLSDHRRLARTLFERAQAAGA
>Mature_467_residues
MHITMTLILQHADVLVTMDAQRREIADGALVANGPAVEWVGPTAELPEQYRRLVDEGRAEVVDMRGHVVMPGLVNTHHHM
YQSLTRAVPAAQDAELFGWLTNLYMLWSHLTPEMIRVSTQTAMAELMLSGCTTTSDHLYLYPNGSRLDDSIDAARQIGMR
FHAARGSMSVGRSQGGLPPDVVVETEAAILRDSQRLVEQYHDASRHAMLRVVLAPCSPFSVSRDLMRESAKMARHYGVSL
HTHLAENDNDIAYSREKFGMTPAQYAEDLGWVGHDVWHAHCVKLDEEGVALFARTGTGVAHCPCSNMRLASGIAPIRRMR
DAGVPVGLGVGGSASNDGAHMLGEARQAMLLQRVGYGPAAMSAREALEIATLGGAKVLNRDDIGALAPGMSADIVAFDMS
GVGYAGAGHDPVAALVFCTPGNVSMSVINGRVVIRDGHLLTADLPNVLSDHRRLARTLFERAQAAGA

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=390, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789249, Length=437, Percent_Identity=29.2906178489703, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87082177, Length=433, Percent_Identity=23.5565819861432, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540282, Length=364, Percent_Identity=22.8021978021978, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319963, Length=343, Percent_Identity=24.4897959183673, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643849, Length=366, Percent_Identity=25.9562841530055, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 50360; Mature: 50360

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHITMTLILQHADVLVTMDAQRREIADGALVANGPAVEWVGPTAELPEQYRRLVDEGRAE
CEEEEEEEEECCCEEEEECCHHHHHCCCCEEECCCEEEECCCCHHHHHHHHHHHHCCCCE
VVDMRGHVVMPGLVNTHHHMYQSLTRAVPAAQDAELFGWLTNLYMLWSHLTPEMIRVSTQ
EEECCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
TAMAELMLSGCTTTSDHLYLYPNGSRLDDSIDAARQIGMRFHAARGSMSVGRSQGGLPPD
HHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
VVVETEAAILRDSQRLVEQYHDASRHAMLRVVLAPCSPFSVSRDLMRESAKMARHYGVSL
EEEECHHHHHHHHHHHHHHHHHHHHHHEEHHEECCCCCHHHHHHHHHHHHHHHHHCCCEE
HTHLAENDNDIAYSREKFGMTPAQYAEDLGWVGHDVWHAHCVKLDEEGVALFARTGTGVA
EEEECCCCCCCEECHHHHCCCHHHHHHHHCCCHHHHHHHHHEEECCCCEEEEEECCCCEE
HCPCSNMRLASGIAPIRRMRDAGVPVGLGVGGSASNDGAHMLGEARQAMLLQRVGYGPAA
ECCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
MSAREALEIATLGGAKVLNRDDIGALAPGMSADIVAFDMSGVGYAGAGHDPVAALVFCTP
HHHHHHHHHEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECC
GNVSMSVINGRVVIRDGHLLTADLPNVLSDHRRLARTLFERAQAAGA
CCCEEEEEECEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHITMTLILQHADVLVTMDAQRREIADGALVANGPAVEWVGPTAELPEQYRRLVDEGRAE
CEEEEEEEEECCCEEEEECCHHHHHCCCCEEECCCEEEECCCCHHHHHHHHHHHHCCCCE
VVDMRGHVVMPGLVNTHHHMYQSLTRAVPAAQDAELFGWLTNLYMLWSHLTPEMIRVSTQ
EEECCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
TAMAELMLSGCTTTSDHLYLYPNGSRLDDSIDAARQIGMRFHAARGSMSVGRSQGGLPPD
HHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
VVVETEAAILRDSQRLVEQYHDASRHAMLRVVLAPCSPFSVSRDLMRESAKMARHYGVSL
EEEECHHHHHHHHHHHHHHHHHHHHHHEEHHEECCCCCHHHHHHHHHHHHHHHHHCCCEE
HTHLAENDNDIAYSREKFGMTPAQYAEDLGWVGHDVWHAHCVKLDEEGVALFARTGTGVA
EEEECCCCCCCEECHHHHCCCHHHHHHHHCCCHHHHHHHHHEEECCCCEEEEEECCCCEE
HCPCSNMRLASGIAPIRRMRDAGVPVGLGVGGSASNDGAHMLGEARQAMLLQRVGYGPAA
ECCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
MSAREALEIATLGGAKVLNRDDIGALAPGMSADIVAFDMSGVGYAGAGHDPVAALVFCTP
HHHHHHHHHEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECC
GNVSMSVINGRVVIRDGHLLTADLPNVLSDHRRLARTLFERAQAAGA
CCCEEEEEECEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]