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The map label for this gene is infC [H]

Identifier: 94310106

GI number: 94310106

Start: 1272089

End: 1272553

Strand: Direct

Name: infC [H]

Synonym: Rmet_1161

Alternate gene names: 94310106

Gene position: 1272089-1272553 (Clockwise)

Preceding gene: 335055517

Following gene: 94310107

Centisome position: 32.38

GC content: 58.71

Gene sequence:

>465_bases
TTGGTAGGGGTTGATAACGAGCAGCTCGGCATCGTCAAATTCATGGACGCACTGCGCCTGGCCGAGGACAAGGACTTGGA
TCTCGTGGAGATCGCGCCCAACGCGACTCCGCCCGTGGCCCGCATCATGGACTACGGCAAGTTCAAGTACGAGGAAGCCA
AGCGCGCCCACGAGGCCAAGCTCAAGCAGAAAATCATCCAGGTCAAGGAAGTGAAATTCCGTCCTGGCACGGATGATGGC
GACTACAACGTCAAGCTGCGCAACTTGCGACGCTTCCTGGAAGAGGGTGACAAGACCAAGATCACGTTGCGCTTCCGTGG
CCGTGAAATGGCCCACCAGGAAATCGGCGCGCGCGTGCTCGAGCGTCTGAAGGCTGACCTGGAGGAACTGGGTCAGGTCG
AGCAGATGCCGAAGATGGAAGGTCGCCAGATGGTGATGGTGCTGGCCCCCAAGAAGAAGAAGTGA

Upstream 100 bases:

>100_bases
GTCGAGCACGGCTTGTTTTTTTGTCTTCTTGAGGTAACGGAACATCGCTACAGACAAAGGTCACCGTATCAACCGGGAAA
TCAGCGCGCCTGAGCTGCGC

Downstream 100 bases:

>100_bases
TTCTTGTGCGGGGTGGCGGCCGGGGTGCCATGTGCATCCCGGCGTCGTCCTGTGCGGAAACCGTGCGCGGCGCTTCGTGT
GCTGCGTACAAAAACAAGTG

Product: protein chain initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVGVDNEQLGIVKFMDALRLAEDKDLDLVEIAPNATPPVARIMDYGKFKYEEAKRAHEAKLKQKIIQVKEVKFRPGTDDG
DYNVKLRNLRRFLEEGDKTKITLRFRGREMAHQEIGARVLERLKADLEELGQVEQMPKMEGRQMVMVLAPKKKK

Sequences:

>Translated_154_residues
MVGVDNEQLGIVKFMDALRLAEDKDLDLVEIAPNATPPVARIMDYGKFKYEEAKRAHEAKLKQKIIQVKEVKFRPGTDDG
DYNVKLRNLRRFLEEGDKTKITLRFRGREMAHQEIGARVLERLKADLEELGQVEQMPKMEGRQMVMVLAPKKKK
>Mature_154_residues
MVGVDNEQLGIVKFMDALRLAEDKDLDLVEIAPNATPPVARIMDYGKFKYEEAKRAHEAKLKQKIIQVKEVKFRPGTDDG
DYNVKLRNLRRFLEEGDKTKITLRFRGREMAHQEIGARVLERLKADLEELGQVEQMPKMEGRQMVMVLAPKKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=155, Percent_Identity=69.0322580645161, Blast_Score=199, Evalue=5e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17808; Mature: 17808

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGVDNEQLGIVKFMDALRLAEDKDLDLVEIAPNATPPVARIMDYGKFKYEEAKRAHEAK
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHH
LKQKIIQVKEVKFRPGTDDGDYNVKLRNLRRFLEEGDKTKITLRFRGREMAHQEIGARVL
HHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHH
ERLKADLEELGQVEQMPKMEGRQMVMVLAPKKKK
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MVGVDNEQLGIVKFMDALRLAEDKDLDLVEIAPNATPPVARIMDYGKFKYEEAKRAHEAK
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHH
LKQKIIQVKEVKFRPGTDDGDYNVKLRNLRRFLEEGDKTKITLRFRGREMAHQEIGARVL
HHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHH
ERLKADLEELGQVEQMPKMEGRQMVMVLAPKKKK
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]