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The map label for this gene is fecR [H]

Identifier: 94310064

GI number: 94310064

Start: 1222378

End: 1223451

Strand: Reverse

Name: fecR [H]

Synonym: Rmet_1119

Alternate gene names: 94310064

Gene position: 1223451-1222378 (Counterclockwise)

Preceding gene: 94310065

Following gene: 94310063

Centisome position: 31.15

GC content: 68.44

Gene sequence:

>1074_bases
ATGCAGCGGTCTTGCGCCCCGGTCGAGAATCCGATGAGCCAATCCGTCGATGTCCGCGAAGCAGCGGCGCGCTGGTTCTC
GCGCAATCAGGCCCCGGCGCTCAGCCCGGCCGAGCAACAGGCATTTGCCGCATGGCTGGCGGCCAGCGCCGAGCATCGCG
CCGAGTACGCGGCGCTCGAACGCGTCTGGCAAGCCGCGGCAGCCATCGATCCGGACAGGCTACGCAAGCTGGCCGTGGAT
GAAAGCGCCTGCCCGACACCCCCACTATCGCCCCCAATATCGCGCCGGGTATCGGCCGGCTGGCGCCCCGCCCTGCTCGG
GCTGTGCGCGGCACTGGCCATCGGCATTGGCTGGATCGGCTGGCAGCATGACGCGGCGGTTGCCACCAACGCTGAATACC
AGACCGCACCGGGCGAACGCAGGACGCTGACGCTCGACGACGGATCGCGCATCGAACTCAATACCCGCTCGCGCCTGGAG
ATTCATTACAGCGCCGGCACCCGTCGCGTGACCTTGCGCGAAGGTGAGGCGATGTTCGAGGTGTCACACGACGCCGCACG
CCCGTTCGTGGTTGATGCGGGCATGGGCACCGTTACCGTAACCGGCACCCGTTTCGACGTCCGACGTGACACATCGGGCG
TGGACGTATCGGTCGAATCCGGCTCGGTAGACGTGAGAGGCAGCGTGAGAGGCAGCGTGAGAGGCAGCGCAAAAGACAGC
GTGAAAGGCAACGCCGGCCGGACACCCGACACGCGCCTGTCCGCAGGGCTCGGCGCGCGCATCGCCAGCGACGGTACCGT
GACCGGCGCGGCCTCGATCGACCTGCCCGGCGTCCTGGCCTGGCGCGAAGGCAAGCTCGTCTTCAACGACGCGCCGCTCT
CGGCCGTGGCGGCCGAAGTCTCCCGCTATCGGCAACAGCCCGTGCGCGTGGCAGATGCCGCGACGGGCAGCCTGCGCGTC
AGCAGCGTGTTCAGCGCCGACGACACGTCGGGCCTGCTGGCCGCGTTGCCGCAGATGCTGCCGGTGGGCGTGCGCAACCT
GCCAGACGGCAGCACCGAAATTTTTTCGCACTAA

Upstream 100 bases:

>100_bases
CCTGCGCGACCAACTGGGCCAACTCTCACCTCACTAGAACAATCTTGTCGATGCCTGCCCCATATCCGTCTGGCGGCGTC
TGCTCCCCCCCAAGCAGCCC

Downstream 100 bases:

>100_bases
GCATTCAGGTTTTTCTTCCGGATTTCGTCTTCTTCCCGATAGCCAGCGAAGCCGCGGCTGTCGTGTTCTGAAGTAATCCA
AGAAAACCTGACGTGACACA

Product: FecR-like transmembrane sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MQRSCAPVENPMSQSVDVREAAARWFSRNQAPALSPAEQQAFAAWLAASAEHRAEYAALERVWQAAAAIDPDRLRKLAVD
ESACPTPPLSPPISRRVSAGWRPALLGLCAALAIGIGWIGWQHDAAVATNAEYQTAPGERRTLTLDDGSRIELNTRSRLE
IHYSAGTRRVTLREGEAMFEVSHDAARPFVVDAGMGTVTVTGTRFDVRRDTSGVDVSVESGSVDVRGSVRGSVRGSAKDS
VKGNAGRTPDTRLSAGLGARIASDGTVTGAASIDLPGVLAWREGKLVFNDAPLSAVAAEVSRYRQQPVRVADAATGSLRV
SSVFSADDTSGLLAALPQMLPVGVRNLPDGSTEIFSH

Sequences:

>Translated_357_residues
MQRSCAPVENPMSQSVDVREAAARWFSRNQAPALSPAEQQAFAAWLAASAEHRAEYAALERVWQAAAAIDPDRLRKLAVD
ESACPTPPLSPPISRRVSAGWRPALLGLCAALAIGIGWIGWQHDAAVATNAEYQTAPGERRTLTLDDGSRIELNTRSRLE
IHYSAGTRRVTLREGEAMFEVSHDAARPFVVDAGMGTVTVTGTRFDVRRDTSGVDVSVESGSVDVRGSVRGSVRGSAKDS
VKGNAGRTPDTRLSAGLGARIASDGTVTGAASIDLPGVLAWREGKLVFNDAPLSAVAAEVSRYRQQPVRVADAATGSLRV
SSVFSADDTSGLLAALPQMLPVGVRNLPDGSTEIFSH
>Mature_357_residues
MQRSCAPVENPMSQSVDVREAAARWFSRNQAPALSPAEQQAFAAWLAASAEHRAEYAALERVWQAAAAIDPDRLRKLAVD
ESACPTPPLSPPISRRVSAGWRPALLGLCAALAIGIGWIGWQHDAAVATNAEYQTAPGERRTLTLDDGSRIELNTRSRLE
IHYSAGTRRVTLREGEAMFEVSHDAARPFVVDAGMGTVTVTGTRFDVRRDTSGVDVSVESGSVDVRGSVRGSVRGSAKDS
VKGNAGRTPDTRLSAGLGARIASDGTVTGAASIDLPGVLAWREGKLVFNDAPLSAVAAEVSRYRQQPVRVADAATGSLRV
SSVFSADDTSGLLAALPQMLPVGVRNLPDGSTEIFSH

Specific function: Regulation of iron dicitrate transport. In the absence of citrate fecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790745, Length=231, Percent_Identity=29.4372294372294, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006860
- InterPro:   IPR012373 [H]

Pfam domain/function: PF04773 FecR [H]

EC number: NA

Molecular weight: Translated: 37794; Mature: 37794

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRSCAPVENPMSQSVDVREAAARWFSRNQAPALSPAEQQAFAAWLAASAEHRAEYAALE
CCCCCCCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RVWQAAAAIDPDRLRKLAVDESACPTPPLSPPISRRVSAGWRPALLGLCAALAIGIGWIG
HHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCC
WQHDAAVATNAEYQTAPGERRTLTLDDGSRIELNTRSRLEIHYSAGTRRVTLREGEAMFE
CCCCCEEEECCCCCCCCCCCEEEEECCCCEEEECCCCEEEEEECCCCEEEEEECCCEEEE
VSHDAARPFVVDAGMGTVTVTGTRFDVRRDTSGVDVSVESGSVDVRGSVRGSVRGSAKDS
ECCCCCCCEEEECCCCEEEEECCEEEEECCCCCCEEEEECCCEEEEECCCCCCCCCCCCC
VKGNAGRTPDTRLSAGLGARIASDGTVTGAASIDLPGVLAWREGKLVFNDAPLSAVAAEV
CCCCCCCCCCCHHHCCCCCEECCCCCEEEEEECCCCCEEEEECCEEEECCCCHHHHHHHH
SRYRQQPVRVADAATGSLRVSSVFSADDTSGLLAALPQMLPVGVRNLPDGSTEIFSH
HHHHHCCCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MQRSCAPVENPMSQSVDVREAAARWFSRNQAPALSPAEQQAFAAWLAASAEHRAEYAALE
CCCCCCCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RVWQAAAAIDPDRLRKLAVDESACPTPPLSPPISRRVSAGWRPALLGLCAALAIGIGWIG
HHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCC
WQHDAAVATNAEYQTAPGERRTLTLDDGSRIELNTRSRLEIHYSAGTRRVTLREGEAMFE
CCCCCEEEECCCCCCCCCCCEEEEECCCCEEEECCCCEEEEEECCCCEEEEEECCCEEEE
VSHDAARPFVVDAGMGTVTVTGTRFDVRRDTSGVDVSVESGSVDVRGSVRGSVRGSAKDS
ECCCCCCCEEEECCCCEEEEECCEEEEECCCCCCEEEEECCCEEEEECCCCCCCCCCCCC
VKGNAGRTPDTRLSAGLGARIASDGTVTGAASIDLPGVLAWREGKLVFNDAPLSAVAAEV
CCCCCCCCCCCHHHCCCCCEECCCCCEEEEEECCCCCEEEEECCEEEECCCCHHHHHHHH
SRYRQQPVRVADAATGSLRVSSVFSADDTSGLLAALPQMLPVGVRNLPDGSTEIFSH
HHHHHCCCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503 [H]