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The map label for this gene is hscB [H]

Identifier: 94309973

GI number: 94309973

Start: 1117466

End: 1117984

Strand: Direct

Name: hscB [H]

Synonym: Rmet_1028

Alternate gene names: 94309973

Gene position: 1117466-1117984 (Clockwise)

Preceding gene: 94309972

Following gene: 94309974

Centisome position: 28.45

GC content: 63.78

Gene sequence:

>519_bases
TTGAAAGACGATTTTTTTGCGCTGTTCGGGCTGCCTGCCCGTTATGAAGTGGACGAGGCCGCGCTGGACGCGGCCTATCG
CACGGTCCAGTCGCAGGCACACCCGGACCGTTTCGCCAATGCGGGCGATGCCGAGCGGCGCGTGGCCATGCAGTGGGCCG
CGCATGCCAACGAGGCATACCGGACGCTGCGCCAGCCGCTCAAGCGCGCGATCTATCTTCTGCATCTGCGGGGCGTCGAT
ATCCAGGCCGAGAGCAATACGGCCATGGCACCCGAATTCCTGATGCAGCAGATGGAATGGCGCGAGGCGCTGCAGGATGC
CGTCGACGGCCGCGCGGTGGATCAGCTGGATCGCCTGCTGCGCGATCTGCGTCAGGAAAAGCTCGAACGCCATGCGGCGC
TTGGCGCGCTGCTTGATGCAGACGACAACGGCGCCGCTGGCGAGGCGGCACGACAGCTAATGTTTATCGAGAAGATCGAA
CACGACGCGAGCGAGGCGATCGATCGTCTCGAGGAATAA

Upstream 100 bases:

>100_bases
GACGAGTGCGGCTGCGGCGAGTCGTTCCGGGTCTGACGGCTTTTGCCGCGAGGCATGCAACAGGGGGCGGCATAGCCGCT
CCTTTTTGTTGGGGAAGCTC

Downstream 100 bases:

>100_bases
AGAAATACCATGGCACTGCTCCAGATTTCCGAACCCGGCATGTCGCCGGCGCCCCATCAGCGCCGATTGGCCGTGGGTAT
CGACCTTGGCACCACCAACT

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKDDFFALFGLPARYEVDEAALDAAYRTVQSQAHPDRFANAGDAERRVAMQWAAHANEAYRTLRQPLKRAIYLLHLRGVD
IQAESNTAMAPEFLMQQMEWREALQDAVDGRAVDQLDRLLRDLRQEKLERHAALGALLDADDNGAAGEAARQLMFIEKIE
HDASEAIDRLEE

Sequences:

>Translated_172_residues
MKDDFFALFGLPARYEVDEAALDAAYRTVQSQAHPDRFANAGDAERRVAMQWAAHANEAYRTLRQPLKRAIYLLHLRGVD
IQAESNTAMAPEFLMQQMEWREALQDAVDGRAVDQLDRLLRDLRQEKLERHAALGALLDADDNGAAGEAARQLMFIEKIE
HDASEAIDRLEE
>Mature_172_residues
MKDDFFALFGLPARYEVDEAALDAAYRTVQSQAHPDRFANAGDAERRVAMQWAAHANEAYRTLRQPLKRAIYLLHLRGVD
IQAESNTAMAPEFLMQQMEWREALQDAVDGRAVDQLDRLLRDLRQEKLERHAALGALLDADDNGAAGEAARQLMFIEKIE
HDASEAIDRLEE

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=157, Percent_Identity=28.0254777070064, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1788876, Length=167, Percent_Identity=37.7245508982036, Blast_Score=117, Evalue=4e-28,
Organism=Drosophila melanogaster, GI161084223, Length=160, Percent_Identity=30, Blast_Score=93, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19506; Mature: 19506

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDDFFALFGLPARYEVDEAALDAAYRTVQSQAHPDRFANAGDAERRVAMQWAAHANEAY
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHH
RTLRQPLKRAIYLLHLRGVDIQAESNTAMAPEFLMQQMEWREALQDAVDGRAVDQLDRLL
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RDLRQEKLERHAALGALLDADDNGAAGEAARQLMFIEKIEHDASEAIDRLEE
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDDFFALFGLPARYEVDEAALDAAYRTVQSQAHPDRFANAGDAERRVAMQWAAHANEAY
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHH
RTLRQPLKRAIYLLHLRGVDIQAESNTAMAPEFLMQQMEWREALQDAVDGRAVDQLDRLL
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RDLRQEKLERHAALGALLDADDNGAAGEAARQLMFIEKIEHDASEAIDRLEE
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA