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The map label for this gene is iscR [H]

Identifier: 94309969

GI number: 94309969

Start: 1114701

End: 1115255

Strand: Direct

Name: iscR [H]

Synonym: Rmet_1024

Alternate gene names: 94309969

Gene position: 1114701-1115255 (Clockwise)

Preceding gene: 94309968

Following gene: 94309970

Centisome position: 28.38

GC content: 63.78

Gene sequence:

>555_bases
ATGAGACTGACCACCAAAGGCCGTTTCGCGGTAACCGCCATGATCGACTTGGCCATGCGCCAGGATCAGGGTCCTGTCAC
CCTGGCAGGCATCAGTCAACGTCAGAAGATCTCCCTGTCGTACCTGGAACAGCTGTTCGGCAAGCTGCGCCGCCACGAAA
TCGTGGAGAGCGTGCGTGGCCCGGGCGGCGGGTACAGTCTCGCCCGCAAGGCCGAGGACGTCACGGTGGCGGACATCATC
ATCGCCGTGGACGAACCGCTCGATGCGACGCAGTGCGGGGGAAAAGGCAATTGTAACGGAGATGACGGCAGCGGACGCTG
CATGACCCACGAACTGTGGGCCACGCTGAACCAGAAGATGGTTGAGTATCTCGACTCCGTCTCCCTGAAGAATCTGGTCG
ACCAGCAGCGCGCCCGCCAGCCGGCGGTGCTGCACGACATGCGCGAAGACGCCGCGCAGCAGCCGGTCGCCGTGTCCCGT
GGCAAGGCGGACAAGCAGGAAAAGCCGGCACGCCCCCGCGTGGTCAATTCGGTATTCAGCCTCGCGCAGTCCTGA

Upstream 100 bases:

>100_bases
TAGCGAGTGGAACACTGCATTGCAGCAAGGGGTACTTGACTGATTTAGTCGGAAAATCTTATACTCGACCGAAATCCTCA
AGTATTCCTCCCCGAGCATC

Downstream 100 bases:

>100_bases
GCAGGGATTTCGCGGCTGCAGTAAACTATCGGTAGACATTAAGCGATTAGCTGTACCTATAAGGCAGTCATAACGATGAG
CACCACCCCACATTTCCCGA

Product: iron sulfur cluster assembly transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRGPGGGYSLARKAEDVTVADII
IAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKMVEYLDSVSLKNLVDQQRARQPAVLHDMREDAAQQPVAVSR
GKADKQEKPARPRVVNSVFSLAQS

Sequences:

>Translated_184_residues
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRGPGGGYSLARKAEDVTVADII
IAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKMVEYLDSVSLKNLVDQQRARQPAVLHDMREDAAQQPVAVSR
GKADKQEKPARPRVVNSVFSLAQS
>Mature_184_residues
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRGPGGGYSLARKAEDVTVADII
IAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKMVEYLDSVSLKNLVDQQRARQPAVLHDMREDAAQQPVAVSR
GKADKQEKPARPRVVNSVFSLAQS

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=136, Percent_Identity=53.6764705882353, Blast_Score=138, Evalue=2e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 20148; Mature: 20148

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYSLARKAEDVTVADIIIAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKM
CCCCCHHHHHCCCCEEHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VEYLDSVSLKNLVDQQRARQPAVLHDMREDAAQQPVAVSRGKADKQEKPARPRVVNSVFS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
LAQS
HHCC
>Mature Secondary Structure
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYSLARKAEDVTVADIIIAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKM
CCCCCHHHHHCCCCEEHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VEYLDSVSLKNLVDQQRARQPAVLHDMREDAAQQPVAVSRGKADKQEKPARPRVVNSVFS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
LAQS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]