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The map label for this gene is tldD [H]

Identifier: 94309936

GI number: 94309936

Start: 1076488

End: 1077948

Strand: Reverse

Name: tldD [H]

Synonym: Rmet_0991

Alternate gene names: 94309936

Gene position: 1077948-1076488 (Counterclockwise)

Preceding gene: 94309937

Following gene: 335055512

Centisome position: 27.44

GC content: 67.28

Gene sequence:

>1461_bases
ATGAACGCTGGCGATCTCGGAATCCGCAACCTGGCCACCGCCCAGCAACTGCTGCTGGCGCCGTACGGGCTCGATGAAGC
CAAGCTCCAGCGCGTGCTGGCCGACATCTTCACGCACAAGGTCGACTACGCCGACCTGTATTTCCAGCACACCCGCAACG
AGGCCTGGAGCCTCGAGGAAGGCATCGTCAAGTCGGGCAGCTTCAGCATCGACCAGGGCGTTGGCGTGCGCGCCGTCTCG
GGCGACAAGACCGCCTTCGCATACTCCGACGACATCAGCCTGCCGGCCCTGAGCCAGGCCGCCGCGGCTACCCGCACGAT
CGGCAAGAGCGGCGGCGGGCGCGTCAAGGTGGCGGGCTCGCTCGCCTCGCACACGGGCCGCAACCTCTACGCGCCGAACG
ATCCGCTCGATTCGATGACCGCCACCGAGAAAGTGGCGCTGCTCGAGAAGATCGAAAAGCTGGCACGCGCCAAGGATCCG
CGCGTGGTGCAGGTCATGGCCGGCCTTGCCGGAGAGTACGACGTGGTGCTGGTGGCGCGCAGCGACGGCGTGATCGCCGC
CGACGTGCGTCCGCTGGTGCGCGTGTCCGTGACCGTCATCGCCGAACAGAACGGTCGGCGCGAGATCGGCTCCTCGGGCG
GCGGCGGCCGCTATGCCTACGGCTACTTTACCGACGACCTGCTGCGCAAATACGTGGACGAAGCGGTGTCGTCGGCGCTG
GTCAACCTGGAGGCGCGTCCCGCCCCGGCTGGCGCGATGACCGTGGTGCTCGGGCCGGGCTGGCCCGGCGTGCTGCTGCA
CGAAGCCGTGGGCCACGGCCTGGAGGGCGACTTCAACCGCAAGGGTTCCTCGGCGTTTGCCGGCCGCATGGGAGAGCGCG
TGGCGGCCAAGGGCGTGACCGTGGTCGACGACGGCACCATCGCCAATCGCCGCGGATCGCTGAACCTCGATGACGAAGGC
AACCCCACGCAGTGCACCACGCTGATCGAGGACGGCATCCTGCGCGGCTATATCCAGGACACGCTCAACGCGCGCCTGAT
GAAGATGCCGGTCACCGGCAACGCACGCCGCGAGAGCTACGCCGCACTGCCGATGCCGCGCATGACCAACACCTACATGC
TTAACGGCGACCGCGATCCGCAGGAAATCCTCGCCAGCGTCAAGCGCGGCCTCTATGCCGTGAACTTCGGCGGCGGTCAG
GTCGACATCACCAACGGCAAGTTCGTGTTCTCGGCCAGCGAGGCATACATGATCGAGGACGGCAAGATCACGTACCCGGT
CAAGGGCGCGACGCTGGTCGGCAACGGCCCTGAATCGCTCAAGGACGTCACGATGATCGGCAACGACATGCGCCTGGATT
CGGGCGTGGGCGTCTGCGGCAAGGAAGGCCAGAGCGTGCCGGTGGGCGTGGGTCAGCCAACGCTGCGGATCGAGAACATG
ACGGTGGGTGGCACGGCCTGA

Upstream 100 bases:

>100_bases
GAACCTGCCGGCACTGCGTCACCGCGTGCTGTAGGATTGACGGAAATTCACATTGCAGGCCACCGTGGCAGACCGCCACG
GGGTATCGAAAAGGACAATC

Downstream 100 bases:

>100_bases
CGGCCGAAGTTCGCCCCTCTCCTGCCTGCGGGAGAGGGGTGCCGCCTGGTCAAGACTACGGCCTCACCTCATACACCAGA
TTGAACGGCGTCTGCGCCGT

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYFQHTRNEAWSLEEGIVKSGSFSIDQGVGVRAVS
GDKTAFAYSDDISLPALSQAAAATRTIGKSGGGRVKVAGSLASHTGRNLYAPNDPLDSMTATEKVALLEKIEKLARAKDP
RVVQVMAGLAGEYDVVLVARSDGVIAADVRPLVRVSVTVIAEQNGRREIGSSGGGGRYAYGYFTDDLLRKYVDEAVSSAL
VNLEARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAGRMGERVAAKGVTVVDDGTIANRRGSLNLDDEG
NPTQCTTLIEDGILRGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDRDPQEILASVKRGLYAVNFGGGQ
VDITNGKFVFSASEAYMIEDGKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
TVGGTA

Sequences:

>Translated_486_residues
MNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYFQHTRNEAWSLEEGIVKSGSFSIDQGVGVRAVS
GDKTAFAYSDDISLPALSQAAAATRTIGKSGGGRVKVAGSLASHTGRNLYAPNDPLDSMTATEKVALLEKIEKLARAKDP
RVVQVMAGLAGEYDVVLVARSDGVIAADVRPLVRVSVTVIAEQNGRREIGSSGGGGRYAYGYFTDDLLRKYVDEAVSSAL
VNLEARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAGRMGERVAAKGVTVVDDGTIANRRGSLNLDDEG
NPTQCTTLIEDGILRGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDRDPQEILASVKRGLYAVNFGGGQ
VDITNGKFVFSASEAYMIEDGKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
TVGGTA
>Mature_486_residues
MNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYFQHTRNEAWSLEEGIVKSGSFSIDQGVGVRAVS
GDKTAFAYSDDISLPALSQAAAATRTIGKSGGGRVKVAGSLASHTGRNLYAPNDPLDSMTATEKVALLEKIEKLARAKDP
RVVQVMAGLAGEYDVVLVARSDGVIAADVRPLVRVSVTVIAEQNGRREIGSSGGGGRYAYGYFTDDLLRKYVDEAVSSAL
VNLEARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAGRMGERVAAKGVTVVDDGTIANRRGSLNLDDEG
NPTQCTTLIEDGILRGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDRDPQEILASVKRGLYAVNFGGGQ
VDITNGKFVFSASEAYMIEDGKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
TVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=483, Percent_Identity=60.4554865424431, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI1790682, Length=430, Percent_Identity=23.0232558139535, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51388; Mature: 51388

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYFQHTRNEAWSLEE
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHH
GIVKSGSFSIDQGVGVRAVSGDKTAFAYSDDISLPALSQAAAATRTIGKSGGGRVKVAGS
HHHCCCCCEECCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEC
LASHTGRNLYAPNDPLDSMTATEKVALLEKIEKLARAKDPRVVQVMAGLAGEYDVVLVAR
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCEEEEEEC
SDGVIAADVRPLVRVSVTVIAEQNGRREIGSSGGGGRYAYGYFTDDLLRKYVDEAVSSAL
CCCEEEECCCCEEEEEEEEEECCCCCHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
VNLEARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAGRMGERVAAKGVT
EECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHCCCE
VVDDGTIANRRGSLNLDDEGNPTQCTTLIEDGILRGYIQDTLNARLMKMPVTGNARRESY
EEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCE
AALPMPRMTNTYMLNGDRDPQEILASVKRGLYAVNFGGGQVDITNGKFVFSASEAYMIED
ECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEEC
GKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
CEEEEEECCCEEECCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
TVGGTA
ECCCCC
>Mature Secondary Structure
MNAGDLGIRNLATAQQLLLAPYGLDEAKLQRVLADIFTHKVDYADLYFQHTRNEAWSLEE
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHH
GIVKSGSFSIDQGVGVRAVSGDKTAFAYSDDISLPALSQAAAATRTIGKSGGGRVKVAGS
HHHCCCCCEECCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEC
LASHTGRNLYAPNDPLDSMTATEKVALLEKIEKLARAKDPRVVQVMAGLAGEYDVVLVAR
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCEEEEEEC
SDGVIAADVRPLVRVSVTVIAEQNGRREIGSSGGGGRYAYGYFTDDLLRKYVDEAVSSAL
CCCEEEECCCCEEEEEEEEEECCCCCHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
VNLEARPAPAGAMTVVLGPGWPGVLLHEAVGHGLEGDFNRKGSSAFAGRMGERVAAKGVT
EECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHCCCE
VVDDGTIANRRGSLNLDDEGNPTQCTTLIEDGILRGYIQDTLNARLMKMPVTGNARRESY
EEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCE
AALPMPRMTNTYMLNGDRDPQEILASVKRGLYAVNFGGGQVDITNGKFVFSASEAYMIED
ECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEEC
GKITYPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
CEEEEEECCCEEECCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
TVGGTA
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]