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The map label for this gene is paaG [H]

Identifier: 94309918

GI number: 94309918

Start: 1058754

End: 1059533

Strand: Reverse

Name: paaG [H]

Synonym: Rmet_0973

Alternate gene names: 94309918

Gene position: 1059533-1058754 (Counterclockwise)

Preceding gene: 94309919

Following gene: 94309917

Centisome position: 26.97

GC content: 65.0

Gene sequence:

>780_bases
GTGACTGCCCAACTACTTTCCGAACGCGTCGACTCGACGCTCGTACTGACCATCTCCAACCCCGAAGCGCGTAACGCGTT
GCATCCGGACATCTACGCCGCTTCGGCGGAAGCGCTCGAAGTCGCCGCCCGCGATGATTCGATCCGCGCCGTGATCCTGA
CGGGTGCCGATGGCGTGTTCTGTGCCGGCGGCAATCTGAACCGGCTGCTCGGCAACCGTTCGCAGCCACCCTCGGTGCAG
GCGGACAGCATCGAAGTCCTCAACCAGTGGATCGAGTCGTTCCACGCCTTCCCCAAGCCGATCATCGCGGCGGTCGAGGG
CCCGGCCGCCGGCGCAGGATTCTCGCTGGTGCTGGCCTGCGATTTCGTCGTGGCCGCCAGCGATGCCAAGTTCGTGATGG
CCTACGTCAAGGTCGGTCTGACGCCAGACGGTGGCGGCTCCTACGAGATCGCGCGTATGCTGCCGCGCCAGCTTGCCAGC
GAGATCATGATGGAAGGCAAACCGGTGGATCCGGCGCGCCTGGCGCACTTCGGCATCGTCAATCGCGTAGCGGCCCCGGG
GCAGGCCCTGACTGAAGCGCTGCGCATCGCCGAAAACCTGGCTAAGGAATCGCCCAACGCGGTCAGCGGCATCAAGTCGC
TGATCAACCACGCGGGCACCGCGACCCTGACCGAGCACCTGGCCGCCGAACGCGACAGCTTCGTGGCCGCACTGCATCAC
AAGGACGGTGGAGAAGGCATCAGCGCGTTCCTTGAGAAGCGCAAGCCAAACTACCGCTAA

Upstream 100 bases:

>100_bases
ACTTGGCCTGTCGTTGCTGACCGAAGAAGCCTGACCCCACGCAGGCGCCCCGACGAGACACGGGGCGCCTTTTTCATTTC
CGCCAGATCAAGAGGCTGTC

Downstream 100 bases:

>100_bases
GCCCCCGAGAAGACACAACACATAAGGACACCCGGAGACAGCATGAGCACCAACGTATCGCACTTTGAAGGCACCCGCCC
CGTGGCCGACCAGCAGCGTT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTAQLLSERVDSTLVLTISNPEARNALHPDIYAASAEALEVAARDDSIRAVILTGADGVFCAGGNLNRLLGNRSQPPSVQ
ADSIEVLNQWIESFHAFPKPIIAAVEGPAAGAGFSLVLACDFVVAASDAKFVMAYVKVGLTPDGGGSYEIARMLPRQLAS
EIMMEGKPVDPARLAHFGIVNRVAAPGQALTEALRIAENLAKESPNAVSGIKSLINHAGTATLTEHLAAERDSFVAALHH
KDGGEGISAFLEKRKPNYR

Sequences:

>Translated_259_residues
MTAQLLSERVDSTLVLTISNPEARNALHPDIYAASAEALEVAARDDSIRAVILTGADGVFCAGGNLNRLLGNRSQPPSVQ
ADSIEVLNQWIESFHAFPKPIIAAVEGPAAGAGFSLVLACDFVVAASDAKFVMAYVKVGLTPDGGGSYEIARMLPRQLAS
EIMMEGKPVDPARLAHFGIVNRVAAPGQALTEALRIAENLAKESPNAVSGIKSLINHAGTATLTEHLAAERDSFVAALHH
KDGGEGISAFLEKRKPNYR
>Mature_258_residues
TAQLLSERVDSTLVLTISNPEARNALHPDIYAASAEALEVAARDDSIRAVILTGADGVFCAGGNLNRLLGNRSQPPSVQA
DSIEVLNQWIESFHAFPKPIIAAVEGPAAGAGFSLVLACDFVVAASDAKFVMAYVKVGLTPDGGGSYEIARMLPRQLASE
IMMEGKPVDPARLAHFGIVNRVAAPGQALTEALRIAENLAKESPNAVSGIKSLINHAGTATLTEHLAAERDSFVAALHHK
DGGEGISAFLEKRKPNYR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=30.4878048780488, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=29.1828793774319, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI116235487, Length=188, Percent_Identity=33.5106382978723, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=30.3846153846154, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI25453481, Length=205, Percent_Identity=28.2926829268293, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI51538573, Length=205, Percent_Identity=28.2926829268293, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI221307494, Length=207, Percent_Identity=29.951690821256, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI221136756, Length=246, Percent_Identity=26.8292682926829, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI221136753, Length=246, Percent_Identity=26.8292682926829, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI4757966, Length=205, Percent_Identity=28.2926829268293, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI51538581, Length=205, Percent_Identity=28.2926829268293, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI4757968, Length=207, Percent_Identity=29.4685990338164, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI49355787, Length=207, Percent_Identity=29.4685990338164, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI260274832, Length=209, Percent_Identity=27.7511961722488, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI45643119, Length=209, Percent_Identity=27.7511961722488, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI260275230, Length=209, Percent_Identity=27.7511961722488, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI70995211, Length=252, Percent_Identity=26.984126984127, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI20127408, Length=176, Percent_Identity=25.5681818181818, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI68989263, Length=189, Percent_Identity=24.3386243386243, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787659, Length=261, Percent_Identity=34.0996168582375, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1787660, Length=259, Percent_Identity=36.6795366795367, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI221142681, Length=268, Percent_Identity=30.2238805970149, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788597, Length=265, Percent_Identity=29.811320754717, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082183, Length=215, Percent_Identity=30.2325581395349, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788682, Length=211, Percent_Identity=29.3838862559242, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790281, Length=173, Percent_Identity=28.3236994219653, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=244, Percent_Identity=33.1967213114754, Blast_Score=133, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=29.9180327868852, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17540714, Length=233, Percent_Identity=28.755364806867, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17535521, Length=249, Percent_Identity=23.6947791164659, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=258, Percent_Identity=25.968992248062, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=249, Percent_Identity=28.5140562248996, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=259, Percent_Identity=25.8687258687259, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=213, Percent_Identity=28.6384976525822, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=226, Percent_Identity=24.7787610619469, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=24.5901639344262, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=183, Percent_Identity=26.2295081967213, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=183, Percent_Identity=26.2295081967213, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=183, Percent_Identity=26.2295081967213, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129971, Length=244, Percent_Identity=32.3770491803279, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24653477, Length=244, Percent_Identity=32.3770491803279, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=29.0566037735849, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI19922422, Length=245, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24654903, Length=251, Percent_Identity=23.9043824701195, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI19920382, Length=207, Percent_Identity=28.9855072463768, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357171, Length=258, Percent_Identity=24.031007751938, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650670, Length=202, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27317; Mature: 27186

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQLLSERVDSTLVLTISNPEARNALHPDIYAASAEALEVAARDDSIRAVILTGADGVF
CCHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHCCHHHHHHHCCCCCEEEEEEECCCEEE
CAGGNLNRLLGNRSQPPSVQADSIEVLNQWIESFHAFPKPIIAAVEGPAAGAGFSLVLAC
ECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHH
DFVVAASDAKFVMAYVKVGLTPDGGGSYEIARMLPRQLASEIMMEGKPVDPARLAHFGIV
HHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
NRVAAPGQALTEALRIAENLAKESPNAVSGIKSLINHAGTATLTEHLAAERDSFVAALHH
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECC
KDGGEGISAFLEKRKPNYR
CCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TAQLLSERVDSTLVLTISNPEARNALHPDIYAASAEALEVAARDDSIRAVILTGADGVF
CHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHCCHHHHHHHCCCCCEEEEEEECCCEEE
CAGGNLNRLLGNRSQPPSVQADSIEVLNQWIESFHAFPKPIIAAVEGPAAGAGFSLVLAC
ECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHH
DFVVAASDAKFVMAYVKVGLTPDGGGSYEIARMLPRQLASEIMMEGKPVDPARLAHFGIV
HHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
NRVAAPGQALTEALRIAENLAKESPNAVSGIKSLINHAGTATLTEHLAAERDSFVAALHH
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECC
KDGGEGISAFLEKRKPNYR
CCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]