BacMap

Definition	Cupriavidus metallidurans CH34 chromosome, complete genome.
Accession	NC_007973
Length	3,928,089

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The map label for this gene is livG9 [H]

Identifier: 94309900

GI number: 94309900

Start: 1041819

End: 1042667

Strand: Direct

Name: livG9 [H]

Synonym: Rmet_0955

Alternate gene names: 94309900

Gene position: 1041819-1042667 (Clockwise)

Preceding gene: 94309899

Following gene: 94309901

Centisome position: 26.52

GC content: 64.43

Gene sequence:

>849_bases
ATGAATTCGGTACTGGGTGAAGGCAAGGCGGAAAGCGGGGATGCCACCGGGCTGGGCCGGATCGTCGAACCCGGCGTCAT
CGACACCACGCACGGTCCGATCCTCTACATCGAGGACCTGACCGTTCAGTTCGACGGCTTTCGCGCGCTGAACAAGCTGT
CGTTGTCGATCGATCACGGTGAACTGCGCTGCGTGATCGGCCCGAATGGCGCCGGCAAGACCACGATGATGGATGTCATC
ACCGGCAAGACCGGGCCGCGCAACGCCAACGTGACCGGGCGTGTGTTTCTGGGGCAGACCATCGACCTGATGCGGCTGAC
CGAACCGCGCATCGCGCAGACCGGCATTGGCCGCAAATTCCAGAAGCCGACCGTGTTCGAGCAGCACGCGGTCTGGGAGA
ACCTGGAACTGGCGATGAAGGCCGACAAGCGCTGGTGGGCGTCGCTGCGTGCCCGGCTGACGCTGGAGGGGCATCGTCGC
ATCGAGGAAACGCTGGCGCTGACCGGGCTCGAGGACGAAGCCTATCGCCCTGCGGGCTTGCTGTCACATGGCCAGAAGCA
GCGGCTCGAGATCGGCATGTTGCTGACGCAGCAGCCTCAGCTCCTGCTGCTCGACGAACCGGTGGCCGGCATGACCGACG
AGGAAACCATGCAACTGGCCGCGCTGCTCAACAGTCTGCGCGGTAGCTGCTCGATGATGGTGGTCGAGCACGACATGGAA
TTCGTCGCCGCGCTGGCCGGTGACGCTGGCACGGTGACCGTGCTGGCGGAAGGCAGCCTGCTGGCCGAAGGCACGCTCGA
CGCCGTGAAGCGCGACGAACGCGTGATCGAATCCTACCTGGGAAGATAA

Upstream 100 bases:

>100_bases
GCCTCTGGCGACGCCTGCGTGATCGGCGCACTTCGAAGGTAGAAACCGGAGCCGCCGATGAAGCGGAAGCCGTGGTGGCG
TCGCAGCAAGGGAGCAAGGC

Downstream 100 bases:

>100_bases
CGATGCTGCAGGTCAACGCAATCAATCAGTTCTACGGCGGCAGCCATATCCTGCGCGACGTATCGTTCGAGGTGCCACAT
GGCAAGCTGACGACGCTGCT

Product: ABC transporter ATP-binding protein (livG-like)

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNSVLGEGKAESGDATGLGRIVEPGVIDTTHGPILYIEDLTVQFDGFRALNKLSLSIDHGELRCVIGPNGAGKTTMMDVI
TGKTGPRNANVTGRVFLGQTIDLMRLTEPRIAQTGIGRKFQKPTVFEQHAVWENLELAMKADKRWWASLRARLTLEGHRR
IEETLALTGLEDEAYRPAGLLSHGQKQRLEIGMLLTQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
FVAALAGDAGTVTVLAEGSLLAEGTLDAVKRDERVIESYLGR

Sequences:

>Translated_282_residues
MNSVLGEGKAESGDATGLGRIVEPGVIDTTHGPILYIEDLTVQFDGFRALNKLSLSIDHGELRCVIGPNGAGKTTMMDVI
TGKTGPRNANVTGRVFLGQTIDLMRLTEPRIAQTGIGRKFQKPTVFEQHAVWENLELAMKADKRWWASLRARLTLEGHRR
IEETLALTGLEDEAYRPAGLLSHGQKQRLEIGMLLTQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
FVAALAGDAGTVTVLAEGSLLAEGTLDAVKRDERVIESYLGR
>Mature_282_residues
MNSVLGEGKAESGDATGLGRIVEPGVIDTTHGPILYIEDLTVQFDGFRALNKLSLSIDHGELRCVIGPNGAGKTTMMDVI
TGKTGPRNANVTGRVFLGQTIDLMRLTEPRIAQTGIGRKFQKPTVFEQHAVWENLELAMKADKRWWASLRARLTLEGHRR
IEETLALTGLEDEAYRPAGLLSHGQKQRLEIGMLLTQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
FVAALAGDAGTVTVLAEGSLLAEGTLDAVKRDERVIESYLGR

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4674

COG function: function code R; Uncharacterized ABC-type transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI150417984, Length=220, Percent_Identity=32.7272727272727, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31657092, Length=253, Percent_Identity=26.4822134387352, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI27436953, Length=223, Percent_Identity=26.0089686098655, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI116734710, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27881501, Length=191, Percent_Identity=28.2722513089005, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI30795238, Length=191, Percent_Identity=28.2722513089005, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789864, Length=259, Percent_Identity=33.976833976834, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87081791, Length=219, Percent_Identity=29.6803652968037, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789593, Length=248, Percent_Identity=27.8225806451613, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790525, Length=258, Percent_Identity=26.3565891472868, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790739, Length=239, Percent_Identity=28.4518828451883, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790190, Length=255, Percent_Identity=28.2352941176471, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786398, Length=225, Percent_Identity=28, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790544, Length=203, Percent_Identity=28.0788177339901, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787370, Length=236, Percent_Identity=26.6949152542373, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788225, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082268, Length=249, Percent_Identity=29.3172690763052, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081709, Length=249, Percent_Identity=25.7028112449799, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788053, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788761, Length=253, Percent_Identity=25.6916996047431, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994943, Length=238, Percent_Identity=31.5126050420168, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787972, Length=246, Percent_Identity=30.0813008130081, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787792, Length=250, Percent_Identity=24.8, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790467, Length=207, Percent_Identity=28.9855072463768, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789991, Length=251, Percent_Identity=27.0916334661355, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48995001, Length=233, Percent_Identity=28.3261802575107, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788472, Length=253, Percent_Identity=24.5059288537549, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788897, Length=245, Percent_Identity=25.3061224489796, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081834, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787029, Length=222, Percent_Identity=25.2252252252252, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788210, Length=252, Percent_Identity=25.7936507936508, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790162, Length=227, Percent_Identity=24.6696035242291, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081782, Length=243, Percent_Identity=27.9835390946502, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786563, Length=214, Percent_Identity=28.5046728971963, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789586, Length=232, Percent_Identity=26.7241379310345, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786872, Length=245, Percent_Identity=26.9387755102041, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786345, Length=245, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786253, Length=235, Percent_Identity=23.4042553191489, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787089, Length=238, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082267, Length=208, Percent_Identity=25.9615384615385, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789873, Length=199, Percent_Identity=24.6231155778894, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789672, Length=224, Percent_Identity=25, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1788450, Length=211, Percent_Identity=28.436018957346, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1787105, Length=219, Percent_Identity=27.8538812785388, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=243, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565586, Length=218, Percent_Identity=28.8990825688073, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=196, Percent_Identity=27.5510204081633, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28574150, Length=222, Percent_Identity=28.8288288288288, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007328, Length=222, Percent_Identity=28.8288288288288, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161076682, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076684, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581617, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581615, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=252, Percent_Identity=24.2063492063492, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920532, Length=179, Percent_Identity=31.2849162011173, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580930, Length=179, Percent_Identity=31.2849162011173, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85816269, Length=170, Percent_Identity=28.8235294117647, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580553, Length=170, Percent_Identity=28.8235294117647, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85724864, Length=170, Percent_Identity=28.8235294117647, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580555, Length=170, Percent_Identity=28.8235294117647, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 30734; Mature: 30734

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVLGEGKAESGDATGLGRIVEPGVIDTTHGPILYIEDLTVQFDGFRALNKLSLSIDHG
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEEECCHHEEEEEEEEEECC
ELRCVIGPNGAGKTTMMDVITGKTGPRNANVTGRVFLGQTIDLMRLTEPRIAQTGIGRKF
EEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHCCCCCC
QKPTVFEQHAVWENLELAMKADKRWWASLRARLTLEGHRRIEETLALTGLEDEAYRPAGL
CCCCCHHHHHHHHCHHHEEHHHHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCCCCCCCHH
LSHGQKQRLEIGMLLTQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
HHCCCHHHEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCHH
FVAALAGDAGTVTVLAEGSLLAEGTLDAVKRDERVIESYLGR
HHHHHCCCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSVLGEGKAESGDATGLGRIVEPGVIDTTHGPILYIEDLTVQFDGFRALNKLSLSIDHG
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEEECCHHEEEEEEEEEECC
ELRCVIGPNGAGKTTMMDVITGKTGPRNANVTGRVFLGQTIDLMRLTEPRIAQTGIGRKF
EEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHCCCCCC
QKPTVFEQHAVWENLELAMKADKRWWASLRARLTLEGHRRIEETLALTGLEDEAYRPAGL
CCCCCHHHHHHHHCHHHEEHHHHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCCCCCCCHH
LSHGQKQRLEIGMLLTQQPQLLLLDEPVAGMTDEETMQLAALLNSLRGSCSMMVVEHDME
HHCCCHHHEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCHH
FVAALAGDAGTVTVLAEGSLLAEGTLDAVKRDERVIESYLGR
HHHHHCCCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]