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The map label for this gene is nuoH [H]

Identifier: 94309879

GI number: 94309879

Start: 1019673

End: 1020737

Strand: Direct

Name: nuoH [H]

Synonym: Rmet_0934

Alternate gene names: 94309879

Gene position: 1019673-1020737 (Clockwise)

Preceding gene: 94309878

Following gene: 94309880

Centisome position: 25.96

GC content: 59.53

Gene sequence:

>1065_bases
ATGATCGACTGGATTACCTCGCAAGGTCACGACATCTTCGGCATGTACTGGACGCCGCTGTGGATTCTTATCCGCGCGGT
GCTCATCGTGGTGCCGGTGCTGCTGTGCGTGGCCTACCTGATTCTGTGGGAGCGCAAGCTGATCGGCTGGATGCACGTGC
GTATCGGCCCGAACCGCGTGGGTCCGCTGGGCTTGCTGCAGCCGATCGCCGACGTGCTGAAGCTGCTGCTCAAGGAAGTC
ATGTTCCCGTCGCAGATCAACCGGGGCATGTACCTGGTGGCTCCGCTGATGGTGCTGATGCCCGCAGTCGCTGTCTGGGC
GGTGATTCCGTTCCAGGCCGAAGTGGTGATGGCCGATATCAACGCTGGTCTGCTGTACGTGATGGCCATCAGCTCGGTGG
GCGTCTATGGCGTGATTCTGGCTGGATGGGCCTCGAACTCGAAGTATGCGTTCATCGGTGCGATGCGTGCCGCGGCGCAG
ATGGTGTCGTACGAAATCGCCATGGGCTTCGCCCTGGTGACCGTGCTGATGGTGTCGGGCAGCCTGAACCTGTCGCACAT
CGTGAACGCCCAGAACACCGGCTACTTCGCCAACATGGGCCTGAACCTGCTGTCGTGGAACTGGCTGCCGCTGCTGCCGA
TGTTCGGCGTGTACTTCATCTCGGGCGTGGCTGAAACCAACCGTCACCCGTTCGACGTGGTGGAAGGCGAATCGGAAATC
GTGGCCGGCCACATGATCGAATATTCGGGCATGACGTTCGCGCTGTTCTTCCTGGCCGAGTACATCAACATGATCATCAT
CTCGACGATGACCTCGCTGATGTTCCTTGGTGGCTGGGCACCGCCGTTCTCGAGCGCGCTGACCAATGCGATCCCGGGCT
TCTTCTGGCTGGTGATCAAGGTATTCCTGCTGCTGTCGGTTTTCATCTGGATTCGCGCTTCGTTCCCGCGTTACCGCTAT
GACCAGATCATGCGTCTGGGCTGGAAGATCTTCATTCCGCTGACCGTGGCTTGGCTGATCATTGTGGCGATCTGGATCAA
GTCGCCGTGGAACATCTGGCACTAA

Upstream 100 bases:

>100_bases
TGCGCTGTTCGGCAATGTCACCGTTGAGAAAGCCATCGACCTGCCGGCCGGCAACAACGCGGCCGCGACGGCCACCGCAT
AAGAAGAGCGAGAAAGCAAC

Downstream 100 bases:

>100_bases
GAGGCCAGGCGATGGTGCGTCACTGCCAGAGGCAGGGCGCGCCGCGCGGAAATACTTAGGAAGCAATCGTCATGCTGCTC
GCCATCAAGGACTTCTTCAA

Product: NADH:ubiquinone oxidoreductase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MIDWITSQGHDIFGMYWTPLWILIRAVLIVVPVLLCVAYLILWERKLIGWMHVRIGPNRVGPLGLLQPIADVLKLLLKEV
MFPSQINRGMYLVAPLMVLMPAVAVWAVIPFQAEVVMADINAGLLYVMAISSVGVYGVILAGWASNSKYAFIGAMRAAAQ
MVSYEIAMGFALVTVLMVSGSLNLSHIVNAQNTGYFANMGLNLLSWNWLPLLPMFGVYFISGVAETNRHPFDVVEGESEI
VAGHMIEYSGMTFALFFLAEYINMIIISTMTSLMFLGGWAPPFSSALTNAIPGFFWLVIKVFLLLSVFIWIRASFPRYRY
DQIMRLGWKIFIPLTVAWLIIVAIWIKSPWNIWH

Sequences:

>Translated_354_residues
MIDWITSQGHDIFGMYWTPLWILIRAVLIVVPVLLCVAYLILWERKLIGWMHVRIGPNRVGPLGLLQPIADVLKLLLKEV
MFPSQINRGMYLVAPLMVLMPAVAVWAVIPFQAEVVMADINAGLLYVMAISSVGVYGVILAGWASNSKYAFIGAMRAAAQ
MVSYEIAMGFALVTVLMVSGSLNLSHIVNAQNTGYFANMGLNLLSWNWLPLLPMFGVYFISGVAETNRHPFDVVEGESEI
VAGHMIEYSGMTFALFFLAEYINMIIISTMTSLMFLGGWAPPFSSALTNAIPGFFWLVIKVFLLLSVFIWIRASFPRYRY
DQIMRLGWKIFIPLTVAWLIIVAIWIKSPWNIWH
>Mature_354_residues
MIDWITSQGHDIFGMYWTPLWILIRAVLIVVPVLLCVAYLILWERKLIGWMHVRIGPNRVGPLGLLQPIADVLKLLLKEV
MFPSQINRGMYLVAPLMVLMPAVAVWAVIPFQAEVVMADINAGLLYVMAISSVGVYGVILAGWASNSKYAFIGAMRAAAQ
MVSYEIAMGFALVTVLMVSGSLNLSHIVNAQNTGYFANMGLNLLSWNWLPLLPMFGVYFISGVAETNRHPFDVVEGESEI
VAGHMIEYSGMTFALFFLAEYINMIIISTMTSLMFLGGWAPPFSSALTNAIPGFFWLVIKVFLLLSVFIWIRASFPRYRY
DQIMRLGWKIFIPLTVAWLIIVAIWIKSPWNIWH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=316, Percent_Identity=43.9873417721519, Blast_Score=256, Evalue=3e-68,
Organism=Escherichia coli, GI1788618, Length=324, Percent_Identity=40.4320987654321, Blast_Score=251, Evalue=5e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39832; Mature: 39832

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDWITSQGHDIFGMYWTPLWILIRAVLIVVPVLLCVAYLILWERKLIGWMHVRIGPNRV
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
GPLGLLQPIADVLKLLLKEVMFPSQINRGMYLVAPLMVLMPAVAVWAVIPFQAEVVMADI
CCHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NAGLLYVMAISSVGVYGVILAGWASNSKYAFIGAMRAAAQMVSYEIAMGFALVTVLMVSG
CCHHHHHHHHHHCCHHHHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLNLSHIVNAQNTGYFANMGLNLLSWNWLPLLPMFGVYFISGVAETNRHPFDVVEGESEI
CCCHHHEECCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHH
VAGHMIEYSGMTFALFFLAEYINMIIISTMTSLMFLGGWAPPFSSALTNAIPGFFWLVIK
HHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VFLLLSVFIWIRASFPRYRYDQIMRLGWKIFIPLTVAWLIIVAIWIKSPWNIWH
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIDWITSQGHDIFGMYWTPLWILIRAVLIVVPVLLCVAYLILWERKLIGWMHVRIGPNRV
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
GPLGLLQPIADVLKLLLKEVMFPSQINRGMYLVAPLMVLMPAVAVWAVIPFQAEVVMADI
CCHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NAGLLYVMAISSVGVYGVILAGWASNSKYAFIGAMRAAAQMVSYEIAMGFALVTVLMVSG
CCHHHHHHHHHHCCHHHHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLNLSHIVNAQNTGYFANMGLNLLSWNWLPLLPMFGVYFISGVAETNRHPFDVVEGESEI
CCCHHHEECCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHH
VAGHMIEYSGMTFALFFLAEYINMIIISTMTSLMFLGGWAPPFSSALTNAIPGFFWLVIK
HHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VFLLLSVFIWIRASFPRYRYDQIMRLGWKIFIPLTVAWLIIVAIWIKSPWNIWH
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA