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The map label for this gene is yggV [C]

Identifier: 94309796

GI number: 94309796

Start: 932043

End: 932657

Strand: Reverse

Name: yggV [C]

Synonym: Rmet_0851

Alternate gene names: 94309796

Gene position: 932657-932043 (Counterclockwise)

Preceding gene: 94309797

Following gene: 94309795

Centisome position: 23.74

GC content: 65.37

Gene sequence:

>615_bases
ATGCAACGTCTGGTTCTGGCCTCCAACAATCCCGGCAAGCTGCGCGAGTTCAGCGCGCTGCTCTCTCCGCTCGGCTTTGA
TGTCGTGCCGCAAGGCGAACTGGGCGTGCCCGAAGCCGAGGAACCGTTCGCCACATTCGTCGAGAACGCGCTGACCAAGG
CCCGCCACGCTGCACGGCTGACGGGAATGCCCGCGCTGGCGGATGACTCGGGTATCTGCGTCGAAGCGCTCGACGGTGCA
CCTGGCGTGTACTCGGCGCGTTATGCCCAGACCGTCGGCAAGCCAAAGTCGGACGCTGCCAACAACGCCCACTTGATCTC
GCAACTGGCAGGCAAACTGAACCGCCGCGCGCACTACTACTGCGTGCTGGTGATGGTGCGGCACGCCGATGATCCGCGCC
CCATCATCGCCGAAGGCATCTGGGCCGGCGAGGTGGTTGACGCCCCGCGCGGCAATGGTGGCTTTGGCTATGATCCGCAC
TTCCTGCTGCCCAGCGTCGGCAAGACGGCCGCCGAGCTGAGCGCCGAAGAGAAGAACGCGATCAGCCATCGTGCCCTGGC
ACTGCAGGAACTGGTGGCCCGCTTGCAGACCGCCGGCATCAAGAGCTGCGCATGA

Upstream 100 bases:

>100_bases
CGACCTCGACGCCATGACGCGCCTGGCCGAGGCCGGCATCGCCGAACTCGTGCGCCACCAGAAGCAGGCGCTCGGGCTGT
AAGCGCAGGGGAATATGTCG

Downstream 100 bases:

>100_bases
TCCCGATCGTCCCTGTCGGCGGTGGCACGCCGGCCACATCCTCGCCGCTATCCCCTGCCGACAACCAGAAGCTTTGGCTC
AAGCCGGGCCAGATCGCCCT

Product: dITP/XTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MQRLVLASNNPGKLREFSALLSPLGFDVVPQGELGVPEAEEPFATFVENALTKARHAARLTGMPALADDSGICVEALDGA
PGVYSARYAQTVGKPKSDAANNAHLISQLAGKLNRRAHYYCVLVMVRHADDPRPIIAEGIWAGEVVDAPRGNGGFGYDPH
FLLPSVGKTAAELSAEEKNAISHRALALQELVARLQTAGIKSCA

Sequences:

>Translated_204_residues
MQRLVLASNNPGKLREFSALLSPLGFDVVPQGELGVPEAEEPFATFVENALTKARHAARLTGMPALADDSGICVEALDGA
PGVYSARYAQTVGKPKSDAANNAHLISQLAGKLNRRAHYYCVLVMVRHADDPRPIIAEGIWAGEVVDAPRGNGGFGYDPH
FLLPSVGKTAAELSAEEKNAISHRALALQELVARLQTAGIKSCA
>Mature_204_residues
MQRLVLASNNPGKLREFSALLSPLGFDVVPQGELGVPEAEEPFATFVENALTKARHAARLTGMPALADDSGICVEALDGA
PGVYSARYAQTVGKPKSDAANNAHLISQLAGKLNRRAHYYCVLVMVRHADDPRPIIAEGIWAGEVVDAPRGNGGFGYDPH
FLLPSVGKTAAELSAEEKNAISHRALALQELVARLQTAGIKSCA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=192, Percent_Identity=31.25, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI31657144, Length=145, Percent_Identity=34.4827586206897, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1789324, Length=198, Percent_Identity=52.020202020202, Blast_Score=208, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17556833, Length=200, Percent_Identity=30, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920712, Length=185, Percent_Identity=32.972972972973, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21622; Mature: 21622

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLVLASNNPGKLREFSALLSPLGFDVVPQGELGVPEAEEPFATFVENALTKARHAARL
CCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGMPALADDSGICVEALDGAPGVYSARYAQTVGKPKSDAANNAHLISQLAGKLNRRAHYY
CCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHE
CVLVMVRHADDPRPIIAEGIWAGEVVDAPRGNGGFGYDPHFLLPSVGKTAAELSAEEKNA
EEEEEEECCCCCCCHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ISHRALALQELVARLQTAGIKSCA
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQRLVLASNNPGKLREFSALLSPLGFDVVPQGELGVPEAEEPFATFVENALTKARHAARL
CCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGMPALADDSGICVEALDGAPGVYSARYAQTVGKPKSDAANNAHLISQLAGKLNRRAHYY
CCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHE
CVLVMVRHADDPRPIIAEGIWAGEVVDAPRGNGGFGYDPHFLLPSVGKTAAELSAEEKNA
EEEEEEECCCCCCCHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ISHRALALQELVARLQTAGIKSCA
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]