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The map label for this gene is ytfL [H]

Identifier: 94309643

GI number: 94309643

Start: 769931

End: 771247

Strand: Reverse

Name: ytfL [H]

Synonym: Rmet_0698

Alternate gene names: 94309643

Gene position: 771247-769931 (Counterclockwise)

Preceding gene: 94309644

Following gene: 94309642

Centisome position: 19.63

GC content: 60.14

Gene sequence:

>1317_bases
ATGTTCGTACTGATCCTGACCCTTCTCGTGGTGGTAAGCGCGTTCTTTTCGATCTCCGAGATCGCCTTGACCGCCGCCCG
CCGCACCAAGCTCCAAGTCCTGTCTGAACGCGGCGACCACCGCGCGACCAAGGTATTGCTGCTCAAGGAGGAGCCCGGCA
ACTTCTTCACCGTGGTACAGATCGGCGTCAACAGCGTGGCGATCCTGGCCGGTATCCTCGGTGAGAAGCATGTCTCGGAT
CTCGTCTACGGATTCCTGAGTGCGTACCTCGATGCCGGCATGGCACAGCGCATCGCCAATGTCAGCTCGTTCCTGATCGT
CACGCTGCTGTTTATCCAGTTCGCGGACCTGATCCCCAAACGCATCGCCATGACCTTCCCTGAGGCGTGCGCGGTTCAGG
TGATCGGCCCGATGCTGACGCTGCTCAAGCTGTTCAAGCCCGTGGTCTGGGTGTTCAATGCAGCGGCCGATGCCACGCTC
AAGCTGTTCGGCATTCCCACCAAGCCGGTCGACCAGATCACCACCGAGGACATCGCCGCCATGGTCGATGCCGGCGCCGA
GGCCGGGGTGCTGCACAAGCACGAACTGCATCTGATCGAAAACGTGTTCGAACTCGATTCGAAACCGATCACGGCCATCA
TGACCCAGCGCGACGACGTGGTGTTCCTGACCCTCGACGACACCGCCGACGGCCTGCGCCGCAAGCTGGTCAAGCAACCG
CACGCCCAATACCCGGTGTGCGGCAAGAATATCGACGACGTGCTGGGCTATATGGAGTCGAAGGTCATCCTGCAACTGCT
ACTGGCCGATGAAAGCGGCGCAGCATTGGACAGCATCGGCAAGCACTATGACAAGAACGTGCTGGTGATCCCGGACACGT
TGACACTCTCGGAGTCACTGACCCGCTTCCGCGAGATGCATGAGAATTTTGCGGTGGTGATGAACGAGTACGGGCTGGTG
GTGGGCATCGTCACGCTGGACGACATCGTCGGCGCGCTGATGGGTGACATCCTCTACTCGAACGAAGACGAACAGATCGT
GCGCCGCGATGAATCTTCGTGGCTGGTCGACGGCCTGACGCCGCTGGTCGACCTGAAGAAGGCACTGGATATCGACGCGC
TGCCTGGCGAAGACTATGTGGATACAGCAGCCGGCCTGGTGATCTACTCGCTGAAGCGGATCCCGAAGAAGTCGGAAGCG
ATCACCGTCGCGGGCTTCCGGTTCGAGGTGGTCGACATCGACCATCACAAGATCGACCAGTTGCTGGTTTCAAGGCTACC
GGCGAGTGCTTCGCAACCTGTGGCTGCTGGTGAGTGA

Upstream 100 bases:

>100_bases
GATCCTGCCCCGCGCTGACTGGCAGACATTTACCAGACAATTGACAGGCCCCCGCCTGTGCACCAATATCAACACGCCCA
GATCGGCGCGTGAATAACTT

Downstream 100 bases:

>100_bases
TGGTGAGTGAAGGCGGCCTGCAGCGCGCAGGCTTTGTCACAAATTGTGACAAATTTTGTCACTCCCAGACGGCTACATGG
ACAAATTACGGCACCTGACA

Product: putative hemolysin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MFVLILTLLVVVSAFFSISEIALTAARRTKLQVLSERGDHRATKVLLLKEEPGNFFTVVQIGVNSVAILAGILGEKHVSD
LVYGFLSAYLDAGMAQRIANVSSFLIVTLLFIQFADLIPKRIAMTFPEACAVQVIGPMLTLLKLFKPVVWVFNAAADATL
KLFGIPTKPVDQITTEDIAAMVDAGAEAGVLHKHELHLIENVFELDSKPITAIMTQRDDVVFLTLDDTADGLRRKLVKQP
HAQYPVCGKNIDDVLGYMESKVILQLLLADESGAALDSIGKHYDKNVLVIPDTLTLSESLTRFREMHENFAVVMNEYGLV
VGIVTLDDIVGALMGDILYSNEDEQIVRRDESSWLVDGLTPLVDLKKALDIDALPGEDYVDTAAGLVIYSLKRIPKKSEA
ITVAGFRFEVVDIDHHKIDQLLVSRLPASASQPVAAGE

Sequences:

>Translated_438_residues
MFVLILTLLVVVSAFFSISEIALTAARRTKLQVLSERGDHRATKVLLLKEEPGNFFTVVQIGVNSVAILAGILGEKHVSD
LVYGFLSAYLDAGMAQRIANVSSFLIVTLLFIQFADLIPKRIAMTFPEACAVQVIGPMLTLLKLFKPVVWVFNAAADATL
KLFGIPTKPVDQITTEDIAAMVDAGAEAGVLHKHELHLIENVFELDSKPITAIMTQRDDVVFLTLDDTADGLRRKLVKQP
HAQYPVCGKNIDDVLGYMESKVILQLLLADESGAALDSIGKHYDKNVLVIPDTLTLSESLTRFREMHENFAVVMNEYGLV
VGIVTLDDIVGALMGDILYSNEDEQIVRRDESSWLVDGLTPLVDLKKALDIDALPGEDYVDTAAGLVIYSLKRIPKKSEA
ITVAGFRFEVVDIDHHKIDQLLVSRLPASASQPVAAGE
>Mature_438_residues
MFVLILTLLVVVSAFFSISEIALTAARRTKLQVLSERGDHRATKVLLLKEEPGNFFTVVQIGVNSVAILAGILGEKHVSD
LVYGFLSAYLDAGMAQRIANVSSFLIVTLLFIQFADLIPKRIAMTFPEACAVQVIGPMLTLLKLFKPVVWVFNAAADATL
KLFGIPTKPVDQITTEDIAAMVDAGAEAGVLHKHELHLIENVFELDSKPITAIMTQRDDVVFLTLDDTADGLRRKLVKQP
HAQYPVCGKNIDDVLGYMESKVILQLLLADESGAALDSIGKHYDKNVLVIPDTLTLSESLTRFREMHENFAVVMNEYGLV
VGIVTLDDIVGALMGDILYSNEDEQIVRRDESSWLVDGLTPLVDLKKALDIDALPGEDYVDTAAGLVIYSLKRIPKKSEA
ITVAGFRFEVVDIDHHKIDQLLVSRLPASASQPVAAGE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=382, Percent_Identity=25.130890052356, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1790664, Length=429, Percent_Identity=46.6200466200466, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI145693175, Length=415, Percent_Identity=24.578313253012, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788119, Length=264, Percent_Identity=29.5454545454545, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082033, Length=259, Percent_Identity=28.957528957529, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786879, Length=266, Percent_Identity=22.9323308270677, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47948; Mature: 47948

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVLILTLLVVVSAFFSISEIALTAARRTKLQVLSERGDHRATKVLLLKEEPGNFFTVVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEE
IGVNSVAILAGILGEKHVSDLVYGFLSAYLDAGMAQRIANVSSFLIVTLLFIQFADLIPK
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAMTFPEACAVQVIGPMLTLLKLFKPVVWVFNAAADATLKLFGIPTKPVDQITTEDIAA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHH
MVDAGAEAGVLHKHELHLIENVFELDSKPITAIMTQRDDVVFLTLDDTADGLRRKLVKQP
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHCC
HAQYPVCGKNIDDVLGYMESKVILQLLLADESGAALDSIGKHYDKNVLVIPDTLTLSESL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCHHHHHHH
TRFREMHENFAVVMNEYGLVVGIVTLDDIVGALMGDILYSNEDEQIVRRDESSWLVDGLT
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHCCH
PLVDLKKALDIDALPGEDYVDTAAGLVIYSLKRIPKKSEAITVAGFRFEVVDIDHHKIDQ
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECCHHHHHH
LLVSRLPASASQPVAAGE
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFVLILTLLVVVSAFFSISEIALTAARRTKLQVLSERGDHRATKVLLLKEEPGNFFTVVQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEE
IGVNSVAILAGILGEKHVSDLVYGFLSAYLDAGMAQRIANVSSFLIVTLLFIQFADLIPK
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAMTFPEACAVQVIGPMLTLLKLFKPVVWVFNAAADATLKLFGIPTKPVDQITTEDIAA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHH
MVDAGAEAGVLHKHELHLIENVFELDSKPITAIMTQRDDVVFLTLDDTADGLRRKLVKQP
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHCC
HAQYPVCGKNIDDVLGYMESKVILQLLLADESGAALDSIGKHYDKNVLVIPDTLTLSESL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCHHHHHHH
TRFREMHENFAVVMNEYGLVVGIVTLDDIVGALMGDILYSNEDEQIVRRDESSWLVDGLT
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHCCH
PLVDLKKALDIDALPGEDYVDTAAGLVIYSLKRIPKKSEAITVAGFRFEVVDIDHHKIDQ
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECCHHHHHH
LLVSRLPASASQPVAAGE
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]