Click here to switch to the map view.

The map label for this gene is ftsK [H]

Identifier: 94309630

GI number: 94309630

Start: 757419

End: 759746

Strand: Direct

Name: ftsK [H]

Synonym: Rmet_0685

Alternate gene names: 94309630

Gene position: 757419-759746 (Clockwise)

Preceding gene: 94309626

Following gene: 94309631

Centisome position: 19.28

GC content: 65.29

Gene sequence:

>2328_bases
ATGGCGCGCGCTACCACGACTACCCGGACCGACCCGTCGGCACTTCCATCGCGTATTGGCAAGCTGCTGGGCGAGGTGCG
CTGGTTCCTGCTGCTGGCCGTCACGCTCGGCTTTCTCTGCGTGCTGGCCAGCTACAGCAAGGCCGATCCCGGCTGGTCTC
ATGCGAGCCAGGTGGCCGACATCCATAACCTTGGCGGCCGTGTGGGCGCCTGGGTGGCCGACGTCCTGTTCTTCATCTTC
GGATTCTCGGCCTACTGGTGGAGCGTGTTGCTGATCCGCCGCTGCTGGCGTGGCTGGCGCGATCTGACCGCCGAACTACC
CGAGCGCGTGCAGGAGCCGCAGCACAGCACGGTCATCAGCTGGATTGGCTTCGGGCTGACGCTGGTGTCCAGCATGGGCC
TGGAGGCGATCCGCATGTATCCGCTGCGCTCGGCCCTGCCGCGCGCGCCCGGTGGCGTGCTGGGTGACCTGCTGGGCGGC
TGGCTGCAGCTTGCGCTCGGCTTCTCCGGCGCCACGCTGCTGTTGCTGCTGCTGTTCGCGATCGGCCTGTCCCTGTTCTT
CCATTTCTCGTGGCTGTCGGTGGCAGAGCACGTCGGCGCCTTCGTCGAAACCCTGTTCATGGGCATCAAGGCTCGCCGCG
AGAACAAGCAAGACCGCATTATCGGCGCTGCTGCCAAGGTGGAGCGCACCGAGACCGTGGAAGTGCAGCGCGTCCGGCAG
GAAGAGGCGCCGCCGATTCAGATCGTGCGCCCGCAGGCGGTGCCCAAGCACGAGCGTGTCGAGCGCGAGAAGCAACAACC
GCTGTTCGCCGATATCCAGGATTCGGACCTGCCGCCGCTGTCGCTGCTCGACCCGATCCCTGTGCATCAGGAAACGGTCA
GCGCCGAAACGCTCGAATACACCTCGCGCCTGATTGAAAAGAAGCTCAAGGACTTCGGCGTGGAGGTCAAGGTCGTGGCC
GCCTATCCGGGCCCCGTCATCACGCGCTACGAAATCGAGCCGGCCACCGGCGTCAAGGGCAGCCAGGTGGTCAATCTGGC
ACGCGATCTGGCGCGTAGCCTGTCGCTGGTGTCGATCCGGGTGGTCGAGACGATACCGGGCAAGAACTACATGGGTCTGG
AGCTTCCGAACCCGAAGCGCCAGACCGTGCGCCTGTCGGAGATCCTGGGCTCACAGGTCTACAACGAGAGCGTGTCGCAC
CTGACCATGGCGCTCGGCAAGGACATCGCCGGCAAGCCGATGGTGGCCGATCTGGCCAGGATGCCGCACTGCATGGTGGC
GGGTACCACGGGCTCGGGCAAGTCGGTGGGTATCAACGCGATGATCCTGTCGCTGCTCTACAAGGCCAAGGCAGATCAGG
TCCGCCTGATCCTGATCGACCCGAAGATGCTCGAAATGAGTGTCTACGAAGGCATTCCGCATCTGCTCTGCCCGGTGGTC
ACCGATATGCGCCAGGCCGGCAACGCGCTGAACTGGGCGGTCGGCGAGATGGAGCGCCGCTACAAGCTCATGAGCAAGCT
CGGCGTGCGCAATCTGGCCGGCTACAACAAGAAGATCGACGAAGCCGCCGCCAGGGAAGAGAAGATTCCGAACCCGTTCA
GCCTGACGCCGGACGCGCCGGAGCCGCTCGACAGGCTGCCGACGATCGTGATCGTGATCGACGAACTGGCCGACCTGATG
ATGGTGGTCGGCAAGAAGGTCGAGGAATTGATCGCCCGGATCGCCCAGAAGGCGCGCGCGGCTGGCCTGCATCTGGTGCT
GGCAACGCAGCGGCCGTCGGTGGACGTGATTACCGGCCTGATCAAGGCCAACGTGCCAACGCGTATCGCATTCCAGGTGA
GCAGCAAGATCGACTCGCGCACGATCCTGGACCAGCAGGGCGCCGAGGCACTGCTCGGCATGGGCGACATGCTTTACCTC
GCGCCGGGCACCGGTTTGCCGGTGCGTGTCCACGGGGCGTTCGTATCCGATGACGAGGTGCATCGCGTGGTCGAAAAGCT
CAAGGAAAGCGGCGAAGCCAACTACATCGAGGGCATTCTCGAAGGCGGTCTGGTCGACGGCGATGGCGCGGGCGACAGCC
TGGGCGGCGGCGCCGGGATTGGCGGTGGCGGCGGTGAGGCCGATCCGCTCTACGATCAGGCCGTGGAGGTGGTGATCAAG
AATCGCCGCGCATCGATCTCGCTGGTGCAGCGCCATCTGCGCATCGGCTACAACCGCGCGGCGCGCTTGCTCGAGGACAT
GGAAAAGGCCGGTCTGGTCTCGGCCATGTCGGGCAACGGCAACCGCGACATCCTCGTGCCGGCCGGCGCGGGCGCGCACG
ACGAATAA

Upstream 100 bases:

>100_bases
CGTTTTGCCGACTGTTGCAAATTCCAATGAGGGCGATAGCCCGGCCAAGGTTAAAATGGCCGCCATCGTTCACTTCGTAC
TCTCGAACCGACCCTGACGC

Downstream 100 bases:

>100_bases
GAGGCGCTATCAAAAAGAAGCGAAGCGGTTCTGGCTAGGCGCGCAACGACGCCAGAATCATTTTGACAGCGCTTCTAAGG
CGTGAGGAGGATGAAACGCG

Product: DNA segregation ATPase ftsk/spoIIIE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 775; Mature: 774

Protein sequence:

>775_residues
MARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKADPGWSHASQVADIHNLGGRVGAWVADVLFFIF
GFSAYWWSVLLIRRCWRGWRDLTAELPERVQEPQHSTVISWIGFGLTLVSSMGLEAIRMYPLRSALPRAPGGVLGDLLGG
WLQLALGFSGATLLLLLLFAIGLSLFFHFSWLSVAEHVGAFVETLFMGIKARRENKQDRIIGAAAKVERTETVEVQRVRQ
EEAPPIQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLSLLDPIPVHQETVSAETLEYTSRLIEKKLKDFGVEVKVVA
AYPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIRVVETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESVSH
LTMALGKDIAGKPMVADLARMPHCMVAGTTGSGKSVGINAMILSLLYKAKADQVRLILIDPKMLEMSVYEGIPHLLCPVV
TDMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAREEKIPNPFSLTPDAPEPLDRLPTIVIVIDELADLM
MVVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYL
APGTGLPVRVHGAFVSDDEVHRVVEKLKESGEANYIEGILEGGLVDGDGAGDSLGGGAGIGGGGGEADPLYDQAVEVVIK
NRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILVPAGAGAHDE

Sequences:

>Translated_775_residues
MARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKADPGWSHASQVADIHNLGGRVGAWVADVLFFIF
GFSAYWWSVLLIRRCWRGWRDLTAELPERVQEPQHSTVISWIGFGLTLVSSMGLEAIRMYPLRSALPRAPGGVLGDLLGG
WLQLALGFSGATLLLLLLFAIGLSLFFHFSWLSVAEHVGAFVETLFMGIKARRENKQDRIIGAAAKVERTETVEVQRVRQ
EEAPPIQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLSLLDPIPVHQETVSAETLEYTSRLIEKKLKDFGVEVKVVA
AYPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIRVVETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESVSH
LTMALGKDIAGKPMVADLARMPHCMVAGTTGSGKSVGINAMILSLLYKAKADQVRLILIDPKMLEMSVYEGIPHLLCPVV
TDMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAREEKIPNPFSLTPDAPEPLDRLPTIVIVIDELADLM
MVVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYL
APGTGLPVRVHGAFVSDDEVHRVVEKLKESGEANYIEGILEGGLVDGDGAGDSLGGGAGIGGGGGEADPLYDQAVEVVIK
NRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILVPAGAGAHDE
>Mature_774_residues
ARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKADPGWSHASQVADIHNLGGRVGAWVADVLFFIFG
FSAYWWSVLLIRRCWRGWRDLTAELPERVQEPQHSTVISWIGFGLTLVSSMGLEAIRMYPLRSALPRAPGGVLGDLLGGW
LQLALGFSGATLLLLLLFAIGLSLFFHFSWLSVAEHVGAFVETLFMGIKARRENKQDRIIGAAAKVERTETVEVQRVRQE
EAPPIQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLSLLDPIPVHQETVSAETLEYTSRLIEKKLKDFGVEVKVVAA
YPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIRVVETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESVSHL
TMALGKDIAGKPMVADLARMPHCMVAGTTGSGKSVGINAMILSLLYKAKADQVRLILIDPKMLEMSVYEGIPHLLCPVVT
DMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAREEKIPNPFSLTPDAPEPLDRLPTIVIVIDELADLMM
VVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLA
PGTGLPVRVHGAFVSDDEVHRVVEKLKESGEANYIEGILEGGLVDGDGAGDSLGGGAGIGGGGGEADPLYDQAVEVVIKN
RRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILVPAGAGAHDE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=497, Percent_Identity=63.1790744466801, Blast_Score=604, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 84239; Mature: 84108

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKADPGWSHASQVAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IHNLGGRVGAWVADVLFFIFGFSAYWWSVLLIRRCWRGWRDLTAELPERVQEPQHSTVIS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
WIGFGLTLVSSMGLEAIRMYPLRSALPRAPGGVLGDLLGGWLQLALGFSGATLLLLLLFA
HHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IGLSLFFHFSWLSVAEHVGAFVETLFMGIKARRENKQDRIIGAAAKVERTETVEVQRVRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHH
EEAPPIQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLSLLDPIPVHQETVSAETLEY
HCCCCEEEECCCCCCCHHHHHHHHCCCCEECCCCCCCCCCHHCCCCCCCHHHHHHHHHHH
TSRLIEKKLKDFGVEVKVVAAYPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIR
HHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEE
VVETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESVSHLTMALGKDIAGKPMVADLAR
EEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
MPHCMVAGTTGSGKSVGINAMILSLLYKAKADQVRLILIDPKMLEMSVYEGIPHLLCPVV
CCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHH
TDMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAREEKIPNPFSLTPDAP
HHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCC
EPLDRLPTIVIVIDELADLMMVVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGL
CHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
IKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAPGTGLPVRVHGAFVSDDEV
HHCCCCCEEEEEEHHCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEEEEEEECCCHHH
HRVVEKLKESGEANYIEGILEGGLVDGDGAGDSLGGGAGIGGGGGEADPLYDQAVEVVIK
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
NRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILVPAGAGAHDE
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
ARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKADPGWSHASQVAD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IHNLGGRVGAWVADVLFFIFGFSAYWWSVLLIRRCWRGWRDLTAELPERVQEPQHSTVIS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
WIGFGLTLVSSMGLEAIRMYPLRSALPRAPGGVLGDLLGGWLQLALGFSGATLLLLLLFA
HHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IGLSLFFHFSWLSVAEHVGAFVETLFMGIKARRENKQDRIIGAAAKVERTETVEVQRVRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHH
EEAPPIQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLSLLDPIPVHQETVSAETLEY
HCCCCEEEECCCCCCCHHHHHHHHCCCCEECCCCCCCCCCHHCCCCCCCHHHHHHHHHHH
TSRLIEKKLKDFGVEVKVVAAYPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIR
HHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEE
VVETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESVSHLTMALGKDIAGKPMVADLAR
EEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
MPHCMVAGTTGSGKSVGINAMILSLLYKAKADQVRLILIDPKMLEMSVYEGIPHLLCPVV
CCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHH
TDMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAREEKIPNPFSLTPDAP
HHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCC
EPLDRLPTIVIVIDELADLMMVVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGL
CHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
IKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAPGTGLPVRVHGAFVSDDEV
HHCCCCCEEEEEEHHCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEEEEEEECCCHHH
HRVVEKLKESGEANYIEGILEGGLVDGDGAGDSLGGGAGIGGGGGEADPLYDQAVEVVIK
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
NRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILVPAGAGAHDE
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]