Click here to switch to the map view.

The map label for this gene is lolA

Identifier: 94309631

GI number: 94309631

Start: 760008

End: 760652

Strand: Direct

Name: lolA

Synonym: Rmet_0686

Alternate gene names: 94309631

Gene position: 760008-760652 (Clockwise)

Preceding gene: 94309630

Following gene: 94309632

Centisome position: 19.35

GC content: 62.17

Gene sequence:

>645_bases
ATGCGATATCGCATTCTTGCTCCCCTGGTTTCCCTGGGCGCCGCACTGGCACTGCTGGCGGCTGCGCCAGTCGCGCAGGC
GGCGGCAACCGACCAGTTGCAAAGCTTCGTGACCAGCGTGAAGACGGCTCGCGGCGAGTTCACGCAGCAGCAAATGAAGG
GGAAGGGCGCCGATCTCAAGGTAGCCAGCACGTCGAGCGGGACGTTTGTGTTCTCGCGCCCCGGCAAGTTCGCGTGGCGC
TATACCAAGCCATACGAGCAACTGCTGCAGGCCGACGGCCAGGTCCTCTACATCTACGACAAGGACCTGAACCAGGTGAC
CGAGCGCAAGCTCGATGGCGCGCTCGGGTCGAGCCCGGCGGCCATCCTGTTCGGCAGCAATGACCTGTCGAAGAACTTCG
ACGTGAAGAATGGGGCCACGCGGGATGGCGTGGAATGGCTGGAACTGACGCCGAAGGAAAAGGACACGCAGTTCGAGCGG
ATCGGCATCGGTTTCAAGGGCGGCAATCTCGAGGCGATGGAGTTGCGTGACGCCTTCGGCAACACGACCATCCTGACTTT
CTCGGCGATCCAGAAGAATCCGTCGCTGCCCGCAGATGCATTCCGCTTCACGGTGCCCAAGGGTGCCGATGTGATGAAGC
AGTGA

Upstream 100 bases:

>100_bases
CGCTCACATGCCGCTGCGGAATTCAGGGCGCCGAATCCGGCTCTAACCCGACATCCCGGCCAGCGCCGGGCATCAGCCAC
TCAAGAAAGGAATCGGATAC

Downstream 100 bases:

>100_bases
GGAGCGCCATGACACACGCCCAAGCATTCCTTTCGTTGCGTCGCCTGGCCGTGCCGGGCGCCACGCTGGCCGCGGCGCTG
GTGCTGTCCGCCTGCGCAAG

Product: lipoprotein chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MRYRILAPLVSLGAALALLAAAPVAQAAATDQLQSFVTSVKTARGEFTQQQMKGKGADLKVASTSSGTFVFSRPGKFAWR
YTKPYEQLLQADGQVLYIYDKDLNQVTERKLDGALGSSPAAILFGSNDLSKNFDVKNGATRDGVEWLELTPKEKDTQFER
IGIGFKGGNLEAMELRDAFGNTTILTFSAIQKNPSLPADAFRFTVPKGADVMKQ

Sequences:

>Translated_214_residues
MRYRILAPLVSLGAALALLAAAPVAQAAATDQLQSFVTSVKTARGEFTQQQMKGKGADLKVASTSSGTFVFSRPGKFAWR
YTKPYEQLLQADGQVLYIYDKDLNQVTERKLDGALGSSPAAILFGSNDLSKNFDVKNGATRDGVEWLELTPKEKDTQFER
IGIGFKGGNLEAMELRDAFGNTTILTFSAIQKNPSLPADAFRFTVPKGADVMKQ
>Mature_214_residues
MRYRILAPLVSLGAALALLAAAPVAQAAATDQLQSFVTSVKTARGEFTQQQMKGKGADLKVASTSSGTFVFSRPGKFAWR
YTKPYEQLLQADGQVLYIYDKDLNQVTERKLDGALGSSPAAILFGSNDLSKNFDVKNGATRDGVEWLELTPKEKDTQFER
IGIGFKGGNLEAMELRDAFGNTTILTFSAIQKNPSLPADAFRFTVPKGADVMKQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=207, Percent_Identity=29.4685990338164, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_RALME (Q1LQK4)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_582841.1
- ProteinModelPortal:   Q1LQK4
- SMR:   Q1LQK4
- STRING:   Q1LQK4
- GeneID:   4037475
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_0686
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   MELRDAF
- ProtClustDB:   PRK00031
- BioCyc:   RMET266264:RMET_0686-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 23249; Mature: 23249

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYRILAPLVSLGAALALLAAAPVAQAAATDQLQSFVTSVKTARGEFTQQQMKGKGADLK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VASTSSGTFVFSRPGKFAWRYTKPYEQLLQADGQVLYIYDKDLNQVTERKLDGALGSSPA
EEECCCCEEEEECCCCEEEEECCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCE
AILFGSNDLSKNFDVKNGATRDGVEWLELTPKEKDTQFERIGIGFKGGNLEAMELRDAFG
EEEECCCCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCHHEECEECCCCEEHEEHHHHCC
NTTILTFSAIQKNPSLPADAFRFTVPKGADVMKQ
CEEEEEEEEHHCCCCCCCHHEEEECCCCCHHHCC
>Mature Secondary Structure
MRYRILAPLVSLGAALALLAAAPVAQAAATDQLQSFVTSVKTARGEFTQQQMKGKGADLK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VASTSSGTFVFSRPGKFAWRYTKPYEQLLQADGQVLYIYDKDLNQVTERKLDGALGSSPA
EEECCCCEEEEECCCCEEEEECCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCE
AILFGSNDLSKNFDVKNGATRDGVEWLELTPKEKDTQFERIGIGFKGGNLEAMELRDAFG
EEEECCCCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCHHEECEECCCCEEHEEHHHHCC
NTTILTFSAIQKNPSLPADAFRFTVPKGADVMKQ
CEEEEEEEEHHCCCCCCCHHEEEECCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA