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The map label for this gene is trxB [H]

Identifier: 94309629

GI number: 94309629

Start: 756284

End: 757237

Strand: Reverse

Name: trxB [H]

Synonym: Rmet_0684

Alternate gene names: 94309629

Gene position: 757237-756284 (Counterclockwise)

Preceding gene: 94309633

Following gene: 94309628

Centisome position: 19.28

GC content: 65.41

Gene sequence:

>954_bases
ATGTCCGCAAAACACGCAAAAGTGCTGATTCTCGGGTCTGGTCCGGCCGGCTACACCGCCGCCGTCTACGCTGCCCGCGC
CAACCTGAACCCGGTGCTGATCACCGGCCTGGCCCAGGGCGGCCAGCTCATGACCACGACCGACGTGGAAAACTGGCCCG
CCGATCCTAACGGCGTGCAGGGCCCGGACTTGATGCAGCGCTTCCTGGCGCACGCCGAACGCTTCAACACGGAAATCATC
TTCGATCACATCCATACGGCCAAGCTGACGGAAAAGCCGATCCGCCTGATCGGCGATTCGGGCGAGTACACCTGCGACGC
CCTGATCATCGCCACCGGCGCGTCCGCCCAGTACCTGGGCCTGCCGTCGGAAGAAGCCTTCATGGGCCGCGGCGTCTCGG
CCTGCGCCACCTGCGACGGTTTCTTCTACAAGAACCAGGAAGTGGCCGTGATCGGTGGCGGCAACACGGCCGTGGAAGAA
GCGCTCTATCTGTCCCATATCGCCAGCAAGGTCACGCTGATCCACCGCCGCGACAAGTTCCGCGCCGAGCCGATCCTGGT
GGACCGCCTGATGCAGCGCGTGGAGGAAGGCCGGATCGACCTGCGCTACGACAGCACGCTGGACGAAGTGCTGGGCGATG
AGTCGGGCGTGACCGGCCTGCGCATCCGCGACACCAAGGACGCCGCCAAGACCGAGGATCTGAAGCTCGCCGGCGTGTTC
GTGGCCATCGGCCACAAGCCGAACACCGACCTGTTCGAAGGCCAGCTCGAGATGAAGAACGGCTACATCGTGACCAAGAG
CGGCCTGTCGGGCGACGCCACGGCCACCAACATCCCGGGCGTGTTCGCCGCCGGCGACGTGCAGGACCACGTCTACCGCC
AGGCCATTACCAGCGCCGGCACGGGCTGCATGGCCGCACTCGACGCGCAACGCTATGTGGAAGCGCTGAAGTAA

Upstream 100 bases:

>100_bases
TGCAACAGTCGGCAAAACGCCATGCCACTTATAATGGCGGTTTCGAGTGACACCGGCGCAACCACCGTGCCGGTGCACGC
GCTGCCTACAGGAACGCATC

Downstream 100 bases:

>100_bases
TCGCTCCCGGGTACCAGGCACTAGCGTCACCGATTCGGGCCGGTTTTTACCGGCCCGATTCCTTATTGGATTCCTTATAA
TCGACGCCGAGCCCCCTGCC

Product: thioredoxin reductase, FAD/NAD(P)-binding protein

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSAKHAKVLILGSGPAGYTAAVYAARANLNPVLITGLAQGGQLMTTTDVENWPADPNGVQGPDLMQRFLAHAERFNTEII
FDHIHTAKLTEKPIRLIGDSGEYTCDALIIATGASAQYLGLPSEEAFMGRGVSACATCDGFFYKNQEVAVIGGGNTAVEE
ALYLSHIASKVTLIHRRDKFRAEPILVDRLMQRVEEGRIDLRYDSTLDEVLGDESGVTGLRIRDTKDAAKTEDLKLAGVF
VAIGHKPNTDLFEGQLEMKNGYIVTKSGLSGDATATNIPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRYVEALK

Sequences:

>Translated_317_residues
MSAKHAKVLILGSGPAGYTAAVYAARANLNPVLITGLAQGGQLMTTTDVENWPADPNGVQGPDLMQRFLAHAERFNTEII
FDHIHTAKLTEKPIRLIGDSGEYTCDALIIATGASAQYLGLPSEEAFMGRGVSACATCDGFFYKNQEVAVIGGGNTAVEE
ALYLSHIASKVTLIHRRDKFRAEPILVDRLMQRVEEGRIDLRYDSTLDEVLGDESGVTGLRIRDTKDAAKTEDLKLAGVF
VAIGHKPNTDLFEGQLEMKNGYIVTKSGLSGDATATNIPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRYVEALK
>Mature_316_residues
SAKHAKVLILGSGPAGYTAAVYAARANLNPVLITGLAQGGQLMTTTDVENWPADPNGVQGPDLMQRFLAHAERFNTEIIF
DHIHTAKLTEKPIRLIGDSGEYTCDALIIATGASAQYLGLPSEEAFMGRGVSACATCDGFFYKNQEVAVIGGGNTAVEEA
LYLSHIASKVTLIHRRDKFRAEPILVDRLMQRVEEGRIDLRYDSTLDEVLGDESGVTGLRIRDTKDAAKTEDLKLAGVFV
AIGHKPNTDLFEGQLEMKNGYIVTKSGLSGDATATNIPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRYVEALK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=72.3809523809524, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI87081763, Length=313, Percent_Identity=35.4632587859425, Blast_Score=147, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6320560, Length=326, Percent_Identity=45.398773006135, Blast_Score=273, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6321898, Length=324, Percent_Identity=45.9876543209877, Blast_Score=271, Evalue=9e-74,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33990; Mature: 33859

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKHAKVLILGSGPAGYTAAVYAARANLNPVLITGLAQGGQLMTTTDVENWPADPNGVQ
CCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCC
GPDLMQRFLAHAERFNTEIIFDHIHTAKLTEKPIRLIGDSGEYTCDALIIATGASAQYLG
CHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCCEEECCCCCEEEEEEEEEECCCCEEEC
LPSEEAFMGRGVSACATCDGFFYKNQEVAVIGGGNTAVEEALYLSHIASKVTLIHRRDKF
CCCCHHHHCCCCHHHEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCC
RAEPILVDRLMQRVEEGRIDLRYDSTLDEVLGDESGVTGLRIRDTKDAAKTEDLKLAGVF
CCCHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEEE
VAIGHKPNTDLFEGQLEMKNGYIVTKSGLSGDATATNIPGVFAAGDVQDHVYRQAITSAG
EEECCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCC
TGCMAALDAQRYVEALK
CCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAKHAKVLILGSGPAGYTAAVYAARANLNPVLITGLAQGGQLMTTTDVENWPADPNGVQ
CCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCC
GPDLMQRFLAHAERFNTEIIFDHIHTAKLTEKPIRLIGDSGEYTCDALIIATGASAQYLG
CHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCCEEECCCCCEEEEEEEEEECCCCEEEC
LPSEEAFMGRGVSACATCDGFFYKNQEVAVIGGGNTAVEEALYLSHIASKVTLIHRRDKF
CCCCHHHHCCCCHHHEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCC
RAEPILVDRLMQRVEEGRIDLRYDSTLDEVLGDESGVTGLRIRDTKDAAKTEDLKLAGVF
CCCHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEEE
VAIGHKPNTDLFEGQLEMKNGYIVTKSGLSGDATATNIPGVFAAGDVQDHVYRQAITSAG
EEECCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCC
TGCMAALDAQRYVEALK
CCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]