| Definition | Cupriavidus metallidurans CH34 chromosome, complete genome. |
|---|---|
| Accession | NC_007973 |
| Length | 3,928,089 |
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The map label for this gene is tsaC [H]
Identifier: 94309620
GI number: 94309620
Start: 747621
End: 748382
Strand: Reverse
Name: tsaC [H]
Synonym: Rmet_0675
Alternate gene names: 94309620
Gene position: 748382-747621 (Counterclockwise)
Preceding gene: 94309621
Following gene: 94309619
Centisome position: 19.05
GC content: 66.4
Gene sequence:
>762_bases ATGGCCAGACTGTCTGGAAAGGTAGCGGTAGTCACGGGTGGTGGTTCGGGCTTTGGCGAGGGCATCGCGCACACGTTCGC GCGCGAAGGCGCCAGCGTGATGGTGGCCGACCTGAACCTGGAAGCCGCCGAACGTGTGGCGGTGGCCATCCGCGAGGCAG GCGGCCAGGCGCGCGCGGTGCGTGCCGACGTGTCGCAAGGCGATGACGTGGCCGCGATGCGCGATGCGACGCTGGCCGCG TTCGGCGACGTCCACTGCGTGGTCAACAACGCCGGCACGACCCATCGCAACAAGCCGATCCTGGAAGTCACCGAAGCCGA GTTCGATCGCGTCTACGCGGTCAACGTCAAGAGCATCTACTGGTCCGCGCATCACTTCATCCCGCATTTCCGCAAGCGCG GCGGCGGCAATTTCGTCAACGTGGCCTCCACCGCCGGCATTCGCCCCCGCCCCGGGCTGGTCTGGTACAACGGCAGCAAG GGCGCGGTCATCGTCGCCAGCAAGGCCATGGCCGCCGAACTTGGCCCCGACAATATCCGCGTCAACTGCGTCAACCCCGT CATTGGCGCCACCGGCCTGCTCGAACAGTTCATGGGCCTGCCTGACACCCCCGAGAACCGCGCGAAGTTCCTGGCCACGA TCCCGATGGGTCGCATGTCCACACCGCAGGACGTGGCCAACGCCTGCCTGTACCTGGCATCAGACGAAGCCGCGTTCATC ACCGGCACCTGCATCGAAGTCGATGGAGGGCGCTGCGTCTGA
Upstream 100 bases:
>100_bases GCATTGCGGGGCAAAGGCCCCTTCCACTGAGCATCCATAGCTGGACGGTTACCAGACGCGGCATGCACCGCGTCCGGACC ACAATCACAGGAGACAAACG
Downstream 100 bases:
>100_bases TCCACGCCCCCGATTCACATCCGATGTGAATCCGAGTCGCCCCAGATCCGTTTTTCCAACCCAGCGGTAACGTCGTATCC CAAAGCAAAACCCGAAAGAG
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 253; Mature: 252
Protein sequence:
>253_residues MARLSGKVAVVTGGGSGFGEGIAHTFAREGASVMVADLNLEAAERVAVAIREAGGQARAVRADVSQGDDVAAMRDATLAA FGDVHCVVNNAGTTHRNKPILEVTEAEFDRVYAVNVKSIYWSAHHFIPHFRKRGGGNFVNVASTAGIRPRPGLVWYNGSK GAVIVASKAMAAELGPDNIRVNCVNPVIGATGLLEQFMGLPDTPENRAKFLATIPMGRMSTPQDVANACLYLASDEAAFI TGTCIEVDGGRCV
Sequences:
>Translated_253_residues MARLSGKVAVVTGGGSGFGEGIAHTFAREGASVMVADLNLEAAERVAVAIREAGGQARAVRADVSQGDDVAAMRDATLAA FGDVHCVVNNAGTTHRNKPILEVTEAEFDRVYAVNVKSIYWSAHHFIPHFRKRGGGNFVNVASTAGIRPRPGLVWYNGSK GAVIVASKAMAAELGPDNIRVNCVNPVIGATGLLEQFMGLPDTPENRAKFLATIPMGRMSTPQDVANACLYLASDEAAFI TGTCIEVDGGRCV >Mature_252_residues ARLSGKVAVVTGGGSGFGEGIAHTFAREGASVMVADLNLEAAERVAVAIREAGGQARAVRADVSQGDDVAAMRDATLAAF GDVHCVVNNAGTTHRNKPILEVTEAEFDRVYAVNVKSIYWSAHHFIPHFRKRGGGNFVNVASTAGIRPRPGLVWYNGSKG AVIVASKAMAAELGPDNIRVNCVNPVIGATGLLEQFMGLPDTPENRAKFLATIPMGRMSTPQDVANACLYLASDEAAFIT GTCIEVDGGRCV
Specific function: Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=31.1740890688259, Blast_Score=122, Evalue=2e-28, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=31.7460317460317, Blast_Score=113, Evalue=1e-25, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=31.5175097276265, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=32.6612903225806, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=33.7719298245614, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=27.6, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=30.4878048780488, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=27.906976744186, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI210032110, Length=193, Percent_Identity=29.0155440414508, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI33667109, Length=230, Percent_Identity=29.5652173913043, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI142976729, Length=242, Percent_Identity=26.0330578512397, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=30.7692307692308, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=31.1475409836066, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=30.1020408163265, Blast_Score=89, Evalue=6e-18, Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=29.9492385786802, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI310128830, Length=203, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI310115468, Length=203, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=30.5019305019305, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI31542939, Length=254, Percent_Identity=25.9842519685039, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI302344755, Length=104, Percent_Identity=37.5, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI25282469, Length=219, Percent_Identity=25.5707762557078, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=25.6, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI4557649, Length=194, Percent_Identity=26.2886597938144, Blast_Score=70, Evalue=1e-12, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=38.3064516129032, Blast_Score=147, Evalue=5e-37, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=32.258064516129, Blast_Score=121, Evalue=5e-29, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.4645669291339, Blast_Score=120, Evalue=7e-29, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=31.8548387096774, Blast_Score=120, Evalue=9e-29, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=32.1285140562249, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=29.2, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=30.6772908366534, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=30.9803921568627, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=28.4584980237154, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=26.8292682926829, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=27.9693486590038, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI2367365, Length=261, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=25.8964143426295, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1787820, Length=229, Percent_Identity=24.4541484716157, Blast_Score=64, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=31.7269076305221, Blast_Score=132, Evalue=2e-31, Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=34.1269841269841, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=31.9838056680162, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=34.2741935483871, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=32.2709163346614, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=31.5985130111524, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=32.5396825396825, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=32.0754716981132, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=30.9701492537313, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=32.3420074349442, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=30.4029304029304, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=30.4511278195489, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=32.2709163346614, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=30.6273062730627, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=30.8270676691729, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=30.8270676691729, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=29.7709923664122, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17564282, Length=171, Percent_Identity=32.7485380116959, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=30.2238805970149, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=30.7984790874525, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=28.3018867924528, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17568967, Length=213, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=30.4832713754647, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=28.996282527881, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17508895, Length=171, Percent_Identity=30.9941520467836, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=30.0751879699248, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=27.9245283018868, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=26.3959390862944, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=26.5625, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=29.6153846153846, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17563726, Length=272, Percent_Identity=26.4705882352941, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=28.6821705426357, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17561272, Length=259, Percent_Identity=28.957528957529, Blast_Score=70, Evalue=9e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=31.0526315789474, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=2e-13, Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=40.234375, Blast_Score=143, Evalue=9e-35, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=36.8, Blast_Score=138, Evalue=4e-33, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=33.2, Blast_Score=134, Evalue=4e-32, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=37.3540856031128, Blast_Score=130, Evalue=8e-31, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=37.007874015748, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=30.952380952381, Blast_Score=117, Evalue=6e-27, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=33.7301587301587, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI281364892, Length=223, Percent_Identity=33.6322869955157, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=31.4432989690722, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=33.984375, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI24649181, Length=188, Percent_Identity=30.8510638297872, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI18859837, Length=216, Percent_Identity=32.4074074074074, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI21355631, Length=216, Percent_Identity=30.5555555555556, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI161076933, Length=197, Percent_Identity=28.9340101522843, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24584748, Length=197, Percent_Identity=28.9340101522843, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=32.421875, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI221510726, Length=198, Percent_Identity=29.7979797979798, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24581726, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI21358495, Length=189, Percent_Identity=28.042328042328, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI28574402, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24584744, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI21357673, Length=213, Percent_Identity=26.7605633802817, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=29.8969072164948, Blast_Score=69, Evalue=4e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.163 [H]
Molecular weight: Translated: 26526; Mature: 26395
Theoretical pI: Translated: 7.10; Mature: 7.10
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 4.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MARLSGKVAVVTGGGSGFGEGIAHTFAREGASVMVADLNLEAAERVAVAIREAGGQARAV CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEE RADVSQGDDVAAMRDATLAAFGDVHCVVNNAGTTHRNKPILEVTEAEFDRVYAVNVKSIY EECCCCCCCEEHHHCCEEEEECCEEEEEECCCCCCCCCCEEEEECCCCCEEEEEEEHHEE WSAHHFIPHFRKRGGGNFVNVASTAGIRPRPGLVWYNGSKGAVIVASKAMAAELGPDNIR EEHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEECHHHHCCCCCCEE VNCVNPVIGATGLLEQFMGLPDTPENRAKFLATIPMGRMSTPQDVANACLYLASDEAAFI EEEECCCCCHHHHHHHHCCCCCCCCCHHEEEEEECCCCCCCHHHHHHHEEEEECCCCEEE TGTCIEVDGGRCV EEEEEEECCCCCC >Mature Secondary Structure ARLSGKVAVVTGGGSGFGEGIAHTFAREGASVMVADLNLEAAERVAVAIREAGGQARAV CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEE RADVSQGDDVAAMRDATLAAFGDVHCVVNNAGTTHRNKPILEVTEAEFDRVYAVNVKSIY EECCCCCCCEEHHHCCEEEEECCEEEEEECCCCCCCCCCEEEEECCCCCEEEEEEEHHEE WSAHHFIPHFRKRGGGNFVNVASTAGIRPRPGLVWYNGSKGAVIVASKAMAAELGPDNIR EEHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEECHHHHCCCCCCEE VNCVNPVIGATGLLEQFMGLPDTPENRAKFLATIPMGRMSTPQDVANACLYLASDEAAFI EEEECCCCCHHHHHHHHCCCCCCCCCHHEEEEEECCCCCCCHHHHHHHEEEEECCCCEEE TGTCIEVDGGRCV EEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12406764 [H]