Click here to switch to the map view.

The map label for this gene is ttuB [H]

Identifier: 94309619

GI number: 94309619

Start: 746198

End: 747511

Strand: Reverse

Name: ttuB [H]

Synonym: Rmet_0674

Alternate gene names: 94309619

Gene position: 747511-746198 (Counterclockwise)

Preceding gene: 94309620

Following gene: 94309612

Centisome position: 19.03

GC content: 64.23

Gene sequence:

>1314_bases
ATGACAACGACCGCAGTCAGTTCCGGCGCGCAAGACGCCGGCTTCGAGGACGCCACCTACCGCAAGGTGAGCTGGCGCCT
GGTGCCCTTCCTGTTGCTCTGTTACGTGGTGGCCTATCTGGACCGCGTCAACGTGGGCTTCGCGAAGCTGCAGATGCTCA
ACGACCTCAAGTTCAGCGAGACGATCTACGGCCTCGGCGCGGGCATCTTCTTCATCGGCTACTTCATCTTCGAAGTGCCG
AGCAACGTGATCCTGCACAAGGTGGGGGCGCGCATCTGGATCGCGCGGATCATGATCACCTGGGGCCTGATCTCGGCGGC
GATGATGTTCGTCACTACGCCGATGATGTTCTACGTGCTGCGCTTTCTGCTGGGCGTGGCGGAAGCGGGCTTCTTCCCGG
GCATCATCCTGTACCTGACCTACTGGTACCCGGCCAGCCGTCGCGGACGCACGACCACGTACTTCATGACGGCCATTGCG
CTGTCCGGCGTGATTGGCGGCCCGCTGTCCGGTTGGCTGATGCAATCGTTCGACGGCCACAACGGCTGGTCGGGATGGCA
ATGGATGTTCCTGGTCGAAGGCATCCCGTCGATCCTGGTGGGCCTGTGGGTGCTGGCGTATCTCGACGACCGCATCACCC
ACGCCAAGTGGCTGACCGATGACGAGAAGGCGCTGCTCCAGCGGAATATCGCCAACGAGGACCAGCACAAGGAAGACCCG
CCCGTGGCCCAGGTGCTGTCGAGCCCGCGCGTGTGGCTGATGAGCGCGATCTACTTCAGCTTCGTGATGGGCCTGTATGG
CGTGAGCTTCTGGCTGCCGACGATCATCAAGCAGACCGGCGTGAAAGGCGCGCTCGATGTGGGCCTGCTGACCGCGATCC
CCTACGGGTGCGCGGTGGTCGGGATGATCCTGTTCGCGCGCAGCGCCGACCGTCGCGGCGAGCGGCGCTGGCATATCGCG
ATTCCGGCGCTGGCCGGCGCGGTGGGTCTGGTGCTGTCGGTGCAATGGCACAGCGACACGACCATGGCGATGGTGGCCCT
GACGATCGCCACGATCGGCATCCTGACCACGCTGCCGCTGTTCTGGAGCCTGCCGACGTCCTTCCTGGCCGGAACCGGCG
CCGCCGCGGGCATCGCGCTGATCAATTCCCTTGGGAACCTGGCTGGCTTCCTGAGCCCCTACGCAGTGGGCTGGCTCAAG
GACATGACGCAAAGTACCGACTCAGGCATGTACCTGCTGGCGGTCTGCATGGTGGTGGGCGCTGCGCTGACGCTGTCGGT
GCCGGCGCGGATGGTGAATCAGAAGAAGGATTGA

Upstream 100 bases:

>100_bases
CCGATTCACATCCGATGTGAATCCGAGTCGCCCCAGATCCGTTTTTCCAACCCAGCGGTAACGTCGTATCCCAAAGCAAA
ACCCGAAAGAGGAGACAGCA

Downstream 100 bases:

>100_bases
GAGATCGAAGGTTTGGGTTGAAGCGCCGCTCTCCCGTAGAACGGGAGAGCGGCACCGGCCGAAGCGAACGGCTTAGGACT
CGCCCAGCATCTGCGCCACC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTTTAVSSGAQDAGFEDATYRKVSWRLVPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETIYGLGAGIFFIGYFIFEVP
SNVILHKVGARIWIARIMITWGLISAAMMFVTTPMMFYVLRFLLGVAEAGFFPGIILYLTYWYPASRRGRTTTYFMTAIA
LSGVIGGPLSGWLMQSFDGHNGWSGWQWMFLVEGIPSILVGLWVLAYLDDRITHAKWLTDDEKALLQRNIANEDQHKEDP
PVAQVLSSPRVWLMSAIYFSFVMGLYGVSFWLPTIIKQTGVKGALDVGLLTAIPYGCAVVGMILFARSADRRGERRWHIA
IPALAGAVGLVLSVQWHSDTTMAMVALTIATIGILTTLPLFWSLPTSFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLK
DMTQSTDSGMYLLAVCMVVGAALTLSVPARMVNQKKD

Sequences:

>Translated_437_residues
MTTTAVSSGAQDAGFEDATYRKVSWRLVPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETIYGLGAGIFFIGYFIFEVP
SNVILHKVGARIWIARIMITWGLISAAMMFVTTPMMFYVLRFLLGVAEAGFFPGIILYLTYWYPASRRGRTTTYFMTAIA
LSGVIGGPLSGWLMQSFDGHNGWSGWQWMFLVEGIPSILVGLWVLAYLDDRITHAKWLTDDEKALLQRNIANEDQHKEDP
PVAQVLSSPRVWLMSAIYFSFVMGLYGVSFWLPTIIKQTGVKGALDVGLLTAIPYGCAVVGMILFARSADRRGERRWHIA
IPALAGAVGLVLSVQWHSDTTMAMVALTIATIGILTTLPLFWSLPTSFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLK
DMTQSTDSGMYLLAVCMVVGAALTLSVPARMVNQKKD
>Mature_436_residues
TTTAVSSGAQDAGFEDATYRKVSWRLVPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETIYGLGAGIFFIGYFIFEVPS
NVILHKVGARIWIARIMITWGLISAAMMFVTTPMMFYVLRFLLGVAEAGFFPGIILYLTYWYPASRRGRTTTYFMTAIAL
SGVIGGPLSGWLMQSFDGHNGWSGWQWMFLVEGIPSILVGLWVLAYLDDRITHAKWLTDDEKALLQRNIANEDQHKEDPP
VAQVLSSPRVWLMSAIYFSFVMGLYGVSFWLPTIIKQTGVKGALDVGLLTAIPYGCAVVGMILFARSADRRGERRWHIAI
PALAGAVGLVLSVQWHSDTTMAMVALTIATIGILTTLPLFWSLPTSFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKD
MTQSTDSGMYLLAVCMVVGAALTLSVPARMVNQKKD

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=300, Percent_Identity=25.3333333333333, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87082071, Length=422, Percent_Identity=37.4407582938389, Blast_Score=281, Evalue=5e-77,
Organism=Escherichia coli, GI1789515, Length=456, Percent_Identity=23.4649122807018, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI2367379, Length=437, Percent_Identity=21.7391304347826, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082320, Length=411, Percent_Identity=22.3844282238443, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789152, Length=438, Percent_Identity=24.2009132420091, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=396, Percent_Identity=21.969696969697, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533554, Length=396, Percent_Identity=21.969696969697, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=190, Percent_Identity=28.4210526315789, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=330, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321698, Length=348, Percent_Identity=24.1379310344828, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324410, Length=162, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319250, Length=213, Percent_Identity=24.4131455399061, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=215, Percent_Identity=26.9767441860465, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321502, Length=374, Percent_Identity=22.4598930481283, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=261, Percent_Identity=25.2873563218391, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584153, Length=362, Percent_Identity=24.0331491712707, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583789, Length=363, Percent_Identity=22.3140495867769, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24653727, Length=410, Percent_Identity=22.1951219512195, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19922400, Length=357, Percent_Identity=26.6106442577031, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24654215, Length=372, Percent_Identity=26.0752688172043, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47956; Mature: 47825

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTTAVSSGAQDAGFEDATYRKVSWRLVPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHH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HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]