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The map label for this gene is ychM [C]

Identifier: 94309551

GI number: 94309551

Start: 656906

End: 658705

Strand: Reverse

Name: ychM [C]

Synonym: Rmet_0606

Alternate gene names: 94309551

Gene position: 658705-656906 (Counterclockwise)

Preceding gene: 94309552

Following gene: 94309550

Centisome position: 16.77

GC content: 67.39

Gene sequence:

>1800_bases
ATGAGACGACAACGGCGGTCGCACCCCTGCCCCCTGCTGTCCAGGCGTCAGTCATCTGGCGCCGCAACGCTGCCCATCCC
CGGGTGGCTTCTGACGTACCGGAAGGAATGGCTGGCGCCCGACGTCATTGCCGGGCTGACCGCCGCCGCCGTGGTCATCC
CCAAGGCCCTGGCCTACGCCACCATCGCGGGCCTGCCTGTCGAGGTCGGCCTGTACACCGTGTTCGCCCCGATGCTGATC
TACGCGCTGCTCGGCAGTTCGCGCACGCTTAGCGTCAGCACCACCACGACACTGGCAATCCTCGTGGCCGCCGCGTTCCG
GCATGTGGGCCCATCGCCCAGCGCCGAAACGCTGATCACGGCCTCAGCCACGCTGACCTTCCTGGTCGGCGCCGTGCTGC
TGGTGGCCCGGCTGCTGAGGCTGGGCTTCGTGGCCGACTTTATCTCCGAGCCAGTGCTGATTGGCTTCAAGGCGGGCATC
GGGCTGGTCATCGTGGTGGACCAGATCCCGAAACTGCTCGGGATGCATTTCCCGAAAGGCCCGTTTTTCCACAATGTGCT
GGCGATCATCCAGAACATTCCTCACGCATCCGTCGCCACGGCCGCGGTCGGCATCCTTATGGTCCTGCTGCTGTTGGGCA
TGGAGCACCGGTTTCCACGTGCACCGGCGCCATTGATCGCGGTGGCCGTCGGCATCATCGGCGTGTGGTTGCTGAACCTG
ACCGCGCATGGGGTGGCCATCGTCGGCGCGGTGCCGACCGGCCTGCCACCGGTCACCCTGCCTGACCCTACGATGATGGA
ACGGCTGTGGCCCGAAGCGCTGGGTATCGCGCTGATGAGCTTCACGGAGACCATCGCCGCCGGGCGAGCGTTCACCCAGG
TTGGCGAGCACGCGCCCGCCGCGAACCGCGAGTTGACGGCCACCGGACTGGCCAACCTCGGCGGCGCGTTCCTCGGCGCG
ATGGCCGCAGGCGGAGGTACGACGCAGACCGCCGTCAACCGGCTGTCGGGGGCGCGCTCGCAACTGGCCGGCCTGGTCAC
GGCGCTGGCCGCGCTTGGCACGATGCTGCTGCTCGCTCCGCTGGTCGGCCGTTTGCCGGAAGCCACGCTGGCCGCGGTGG
TCATCGTCTACTCCGTCTCTCTGATCAAGCCGGCCGAATTTCTGGCGATCCTTGGCATCCGCCGCACCGAATTCATCTGG
GCGCTGGTCGCCCTGGCTGGCGTGGTGGCCCTGGGCACGCTGCAGGGCATCGTCGTGGCGATCGTCGTATCGATGCTGGC
CCTGGCCTATCAGACCTCCGATCCGCCGGTCTACAAGCTGGCGCGCAAGCCCGGCACCAACGTATTCCGTCCGCAATCAG
ACGCGCACCCACACGACGAGACCGTGCCCGGCCTGCTGATGCTACGGCCCGAGGGGCGCGTCTACTTCGTCAACGCGCGG
CGTATCGGTCACAAACTTCGGCCAATGATCCTGCACGACAAGCCGAAGGTGGTCGCGCTCGACCTGACCGCCGTCTCTGA
CATGGAATACACGGCGCTGCACATGCTGACCGATGCCGAACGCGTGCTGCGCGAGGAGGATGGCGTCATGCTCTGGCTGG
TCGGGATGAATCCCGACGTGCTCGACATGGTCCGGCGCTCGGCGCTGGGCCAGACCCTGACGCATGAGCGGATGTTCTTC
ACGATGGACCTGGCCGCGGTCCGGTTCCAGACGGAACACGCCGATGCCGTGTGGGGGCCCATGACACAGCCAGGCACGCC
GCCAGACACGCCGCCGCCCGAGTCCCGCCCACCCGGTTAA

Upstream 100 bases:

>100_bases
AGGCGAGCTGCGCGTAACCAGACCACTGACACGCCGTCCTTGCGGCGGCCGTGATCGCGCCTAGACTCAGGTTCTGTGAA
GTCCGCTCGGAAACAGAACC

Downstream 100 bases:

>100_bases
ACTCCTGCCTGGTGGATTTCCCCGTCCGCCCTGTCGGCGCCAGACGGAGGCATCGCGACGTATTCGCGGCCTGCCTCCGC
CCGGCGCTGTCGATCGTTCC

Product: Sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MRRQRRSHPCPLLSRRQSSGAATLPIPGWLLTYRKEWLAPDVIAGLTAAAVVIPKALAYATIAGLPVEVGLYTVFAPMLI
YALLGSSRTLSVSTTTTLAILVAAAFRHVGPSPSAETLITASATLTFLVGAVLLVARLLRLGFVADFISEPVLIGFKAGI
GLVIVVDQIPKLLGMHFPKGPFFHNVLAIIQNIPHASVATAAVGILMVLLLLGMEHRFPRAPAPLIAVAVGIIGVWLLNL
TAHGVAIVGAVPTGLPPVTLPDPTMMERLWPEALGIALMSFTETIAAGRAFTQVGEHAPAANRELTATGLANLGGAFLGA
MAAGGGTTQTAVNRLSGARSQLAGLVTALAALGTMLLLAPLVGRLPEATLAAVVIVYSVSLIKPAEFLAILGIRRTEFIW
ALVALAGVVALGTLQGIVVAIVVSMLALAYQTSDPPVYKLARKPGTNVFRPQSDAHPHDETVPGLLMLRPEGRVYFVNAR
RIGHKLRPMILHDKPKVVALDLTAVSDMEYTALHMLTDAERVLREEDGVMLWLVGMNPDVLDMVRRSALGQTLTHERMFF
TMDLAAVRFQTEHADAVWGPMTQPGTPPDTPPPESRPPG

Sequences:

>Translated_599_residues
MRRQRRSHPCPLLSRRQSSGAATLPIPGWLLTYRKEWLAPDVIAGLTAAAVVIPKALAYATIAGLPVEVGLYTVFAPMLI
YALLGSSRTLSVSTTTTLAILVAAAFRHVGPSPSAETLITASATLTFLVGAVLLVARLLRLGFVADFISEPVLIGFKAGI
GLVIVVDQIPKLLGMHFPKGPFFHNVLAIIQNIPHASVATAAVGILMVLLLLGMEHRFPRAPAPLIAVAVGIIGVWLLNL
TAHGVAIVGAVPTGLPPVTLPDPTMMERLWPEALGIALMSFTETIAAGRAFTQVGEHAPAANRELTATGLANLGGAFLGA
MAAGGGTTQTAVNRLSGARSQLAGLVTALAALGTMLLLAPLVGRLPEATLAAVVIVYSVSLIKPAEFLAILGIRRTEFIW
ALVALAGVVALGTLQGIVVAIVVSMLALAYQTSDPPVYKLARKPGTNVFRPQSDAHPHDETVPGLLMLRPEGRVYFVNAR
RIGHKLRPMILHDKPKVVALDLTAVSDMEYTALHMLTDAERVLREEDGVMLWLVGMNPDVLDMVRRSALGQTLTHERMFF
TMDLAAVRFQTEHADAVWGPMTQPGTPPDTPPPESRPPG
>Mature_599_residues
MRRQRRSHPCPLLSRRQSSGAATLPIPGWLLTYRKEWLAPDVIAGLTAAAVVIPKALAYATIAGLPVEVGLYTVFAPMLI
YALLGSSRTLSVSTTTTLAILVAAAFRHVGPSPSAETLITASATLTFLVGAVLLVARLLRLGFVADFISEPVLIGFKAGI
GLVIVVDQIPKLLGMHFPKGPFFHNVLAIIQNIPHASVATAAVGILMVLLLLGMEHRFPRAPAPLIAVAVGIIGVWLLNL
TAHGVAIVGAVPTGLPPVTLPDPTMMERLWPEALGIALMSFTETIAAGRAFTQVGEHAPAANRELTATGLANLGGAFLGA
MAAGGGTTQTAVNRLSGARSQLAGLVTALAALGTMLLLAPLVGRLPEATLAAVVIVYSVSLIKPAEFLAILGIRRTEFIW
ALVALAGVVALGTLQGIVVAIVVSMLALAYQTSDPPVYKLARKPGTNVFRPQSDAHPHDETVPGLLMLRPEGRVYFVNAR
RIGHKLRPMILHDKPKVVALDLTAVSDMEYTALHMLTDAERVLREEDGVMLWLVGMNPDVLDMVRRSALGQTLTHERMFF
TMDLAAVRFQTEHADAVWGPMTQPGTPPDTPPPESRPPG

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI39752683, Length=497, Percent_Identity=26.9617706237425, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI45827800, Length=497, Percent_Identity=26.9617706237425, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI94721259, Length=490, Percent_Identity=28.1632653061224, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI94721257, Length=490, Percent_Identity=28.1632653061224, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI94721255, Length=490, Percent_Identity=28.1632653061224, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI94721253, Length=490, Percent_Identity=28.1632653061224, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI262206105, Length=598, Percent_Identity=29.5986622073579, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI262206075, Length=598, Percent_Identity=29.5986622073579, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI262206069, Length=598, Percent_Identity=29.5986622073579, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI262206063, Length=598, Percent_Identity=29.5986622073579, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI269784651, Length=494, Percent_Identity=25.3036437246964, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI45827802, Length=442, Percent_Identity=26.9230769230769, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI4505697, Length=547, Percent_Identity=24.3144424131627, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4557535, Length=509, Percent_Identity=25.7367387033399, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI47131207, Length=502, Percent_Identity=28.8844621513944, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI20336272, Length=502, Percent_Identity=28.8844621513944, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI16418413, Length=512, Percent_Identity=24.8046875, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI217272867, Length=512, Percent_Identity=24.8046875, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI100913030, Length=622, Percent_Identity=23.1511254019293, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI16418457, Length=507, Percent_Identity=24.8520710059172, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI301601599, Length=507, Percent_Identity=24.8520710059172, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI20336282, Length=529, Percent_Identity=23.4404536862004, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI16306483, Length=529, Percent_Identity=23.4404536862004, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI65506789, Length=344, Percent_Identity=29.6511627906977, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI45827804, Length=277, Percent_Identity=27.7978339350181, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI301601602, Length=253, Percent_Identity=25.6916996047431, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI20336274, Length=116, Percent_Identity=36.2068965517241, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87081859, Length=374, Percent_Identity=27.807486631016, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17551690, Length=543, Percent_Identity=25.2302025782689, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI86564196, Length=491, Percent_Identity=26.8839103869654, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17566848, Length=595, Percent_Identity=24.3697478991597, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17562578, Length=497, Percent_Identity=26.3581488933602, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI86565215, Length=570, Percent_Identity=21.9298245614035, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193203292, Length=510, Percent_Identity=23.921568627451, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI86564876, Length=534, Percent_Identity=22.6591760299625, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI86565213, Length=270, Percent_Identity=24.8148148148148, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI86565209, Length=240, Percent_Identity=22.9166666666667, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI86565211, Length=240, Percent_Identity=22.9166666666667, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325260, Length=581, Percent_Identity=25.473321858864, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323121, Length=396, Percent_Identity=25.5050505050505, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6319771, Length=394, Percent_Identity=25.6345177664975, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24649801, Length=600, Percent_Identity=25.8333333333333, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21358229, Length=470, Percent_Identity=28.2978723404255, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI85815873, Length=476, Percent_Identity=28.5714285714286, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24647160, Length=565, Percent_Identity=26.7256637168142, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21355087, Length=565, Percent_Identity=26.7256637168142, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24651449, Length=470, Percent_Identity=26.3829787234043, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI19922482, Length=459, Percent_Identity=26.3616557734205, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666186, Length=527, Percent_Identity=25.2371916508539, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24663084, Length=560, Percent_Identity=26.9642857142857, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21357695, Length=560, Percent_Identity=26.9642857142857, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21358633, Length=537, Percent_Identity=25.3258845437616, Blast_Score=130, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 63536; Mature: 63536

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQRRSHPCPLLSRRQSSGAATLPIPGWLLTYRKEWLAPDVIAGLTAAAVVIPKALAYA
CCCCCCCCCCCHHHCCCCCCCEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TIAGLPVEVGLYTVFAPMLIYALLGSSRTLSVSTTTTLAILVAAAFRHVGPSPSAETLIT
HHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEE
ASATLTFLVGAVLLVARLLRLGFVADFISEPVLIGFKAGIGLVIVVDQIPKLLGMHFPKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEHHHHHHHHCCCCCCC
PFFHNVLAIIQNIPHASVATAAVGILMVLLLLGMEHRFPRAPAPLIAVAVGIIGVWLLNL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TAHGVAIVGAVPTGLPPVTLPDPTMMERLWPEALGIALMSFTETIAAGRAFTQVGEHAPA
HHCCEEEEEECCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ANRELTATGLANLGGAFLGAMAAGGGTTQTAVNRLSGARSQLAGLVTALAALGTMLLLAP
CCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGRLPEATLAAVVIVYSVSLIKPAEFLAILGIRRTEFIWALVALAGVVALGTLQGIVVA
HHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVVSMLALAYQTSDPPVYKLARKPGTNVFRPQSDAHPHDETVPGLLMLRPEGRVYFVNAR
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEHH
RIGHKLRPMILHDKPKVVALDLTAVSDMEYTALHMLTDAERVLREEDGVMLWLVGMNPDV
HHCCCCCCCEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
LDMVRRSALGQTLTHERMFFTMDLAAVRFQTEHADAVWGPMTQPGTPPDTPPPESRPPG
HHHHHHHHHHHHHHHHHHEEEEHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRQRRSHPCPLLSRRQSSGAATLPIPGWLLTYRKEWLAPDVIAGLTAAAVVIPKALAYA
CCCCCCCCCCCHHHCCCCCCCEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TIAGLPVEVGLYTVFAPMLIYALLGSSRTLSVSTTTTLAILVAAAFRHVGPSPSAETLIT
HHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEE
ASATLTFLVGAVLLVARLLRLGFVADFISEPVLIGFKAGIGLVIVVDQIPKLLGMHFPKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEHHHHHHHHCCCCCCC
PFFHNVLAIIQNIPHASVATAAVGILMVLLLLGMEHRFPRAPAPLIAVAVGIIGVWLLNL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TAHGVAIVGAVPTGLPPVTLPDPTMMERLWPEALGIALMSFTETIAAGRAFTQVGEHAPA
HHCCEEEEEECCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ANRELTATGLANLGGAFLGAMAAGGGTTQTAVNRLSGARSQLAGLVTALAALGTMLLLAP
CCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGRLPEATLAAVVIVYSVSLIKPAEFLAILGIRRTEFIWALVALAGVVALGTLQGIVVA
HHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVVSMLALAYQTSDPPVYKLARKPGTNVFRPQSDAHPHDETVPGLLMLRPEGRVYFVNAR
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEHH
RIGHKLRPMILHDKPKVVALDLTAVSDMEYTALHMLTDAERVLREEDGVMLWLVGMNPDV
HHCCCCCCCEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
LDMVRRSALGQTLTHERMFFTMDLAAVRFQTEHADAVWGPMTQPGTPPDTPPPESRPPG
HHHHHHHHHHHHHHHHHHEEEEHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]