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The map label for this gene is sucD [H]

Identifier: 94309415

GI number: 94309415

Start: 499606

End: 500487

Strand: Direct

Name: sucD [H]

Synonym: Rmet_0470

Alternate gene names: 94309415

Gene position: 499606-500487 (Clockwise)

Preceding gene: 94309414

Following gene: 335055494

Centisome position: 12.72

GC content: 61.68

Gene sequence:

>882_bases
ATGAGCATTCTGATCAACAAGGACACCAAGGTCATCACCCAGGGCATCACCGGCAAGACGGGCCAGTTCCACACCCGCGG
CTGCCGTGACTATGCCAATGGCAAGAACTGCTTCGTGGCAGGCGTGAACCCGAAGAAGGCCGGTGAAGATTTCGAAGGCA
TTCCCATCTACGCAAGCGTCAAGGATGCCAAGGAACAAACCGGCGCGACCGTGTCGGTGATCTACGTGCCGCCCGCAGGC
GCCGCTGCCGCCATCTGGGAAGCCGTTGATGCCGATCTGGACCTGGTGGTCTGCATCACCGAAGGCATCCCCGTCCGCGA
CATGATGGAAGTCAAGGACAAGATGCGTCGCCAGAACAAGAAGACGCTGCTGCTCGGACCGAACTGCCCGGGCCTGATCA
CGCCGGACGAGATCAAGATCGGCATCATGCCGGGTCACATCCACCGCAAGGGCCGCATCGGCGTGGTGTCGCGCTCGGGC
ACGCTGACGTATGAAGCCGTGGGCCAGCTGACCGCGCTGGGCCTGGGCCAGTCGTCGGCCGTCGGTATCGGTGGCGATCC
GATCAACGGTCTGAAGCACATCGACGTGATGAAGATGTTCAACGACGATCCGGAAACGGACGCCGTGGTCATGATCGGTG
AGATCGGTGGTCCGGACGAAGCCAACGCGGCTTACTGGATCAAGGAAAACATGAAGAAGCCGGTGGTTGGCTTCATCGCT
GGCGTGACCGCGCCTCCGGGCAAGCGCATGGGCCACGCTGGCGCGCTGATCTCGGGCGGTGCCGACACTGCCCAGGCCAA
GCTGGAAATCATGGAAGCCTGCGGTATCAAGGTCACCAAGAACCCGTCGGAAATGGGCCGCCTGCTGAAGGCAATGCTGT
AA

Upstream 100 bases:

>100_bases
GAAGCCGCCCAGAAGGTCGTGGCCGCCGTCGCTGGCAAGTAAGGACAACTTTCGTTGCCGCCTGGCCGCAGCCGGGCGGG
GCGACTAAAAGGACTAGCAA

Downstream 100 bases:

>100_bases
GGCATTCCCACCGATGTCGCTTGTGTGTGCTCTTAATGGCACGTGCAGAGCGATTGCCGTACCTGCGGCGCATGCCGGCT
CCTGCCGGAGCGCATCGCCG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASVKDAKEQTGATVSVIYVPPAG
AAAAIWEAVDADLDLVVCITEGIPVRDMMEVKDKMRRQNKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKENMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAQAKLEIMEACGIKVTKNPSEMGRLLKAML

Sequences:

>Translated_293_residues
MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASVKDAKEQTGATVSVIYVPPAG
AAAAIWEAVDADLDLVVCITEGIPVRDMMEVKDKMRRQNKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKENMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAQAKLEIMEACGIKVTKNPSEMGRLLKAML
>Mature_292_residues
SILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASVKDAKEQTGATVSVIYVPPAGA
AAAIWEAVDADLDLVVCITEGIPVRDMMEVKDKMRRQNKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGT
LTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKENMKKPVVGFIAG
VTAPPGKRMGHAGALISGGADTAQAKLEIMEACGIKVTKNPSEMGRLLKAML

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=288, Percent_Identity=56.25, Blast_Score=274, Evalue=8e-74,
Organism=Homo sapiens, GI38569421, Length=253, Percent_Identity=27.6679841897233, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI38569423, Length=253, Percent_Identity=27.6679841897233, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=54.6075085324232, Blast_Score=314, Evalue=4e-87,
Organism=Escherichia coli, GI1786513, Length=185, Percent_Identity=29.1891891891892, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=289, Percent_Identity=56.401384083045, Blast_Score=305, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17553126, Length=297, Percent_Identity=53.8720538720539, Blast_Score=298, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17557344, Length=254, Percent_Identity=26.3779527559055, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551266, Length=254, Percent_Identity=25.1968503937008, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=48.3108108108108, Blast_Score=265, Evalue=8e-72,
Organism=Drosophila melanogaster, GI21356559, Length=297, Percent_Identity=51.1784511784512, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI28574296, Length=296, Percent_Identity=53.7162162162162, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI281363477, Length=250, Percent_Identity=27.6, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281363475, Length=250, Percent_Identity=27.6, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281363473, Length=250, Percent_Identity=27.6, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30907; Mature: 30776

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASV
CEEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCHHHCCCCCCCEEEEEEC
KDAKEQTGATVSVIYVPPAGAAAAIWEAVDADLDLVVCITEGIPVRDMMEVKDKMRRQNK
CHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGTLTYEAVGQLTALGLGQSSA
CEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHCCCEECCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKENMKKPVVGFIA
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEHHCCCCCCEEHEE
GVTAPPGKRMGHAGALISGGADTAQAKLEIMEACGIKVTKNPSEMGRLLKAML
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHC
>Mature Secondary Structure 
SILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASV
EEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCHHHCCCCCCCEEEEEEC
KDAKEQTGATVSVIYVPPAGAAAAIWEAVDADLDLVVCITEGIPVRDMMEVKDKMRRQNK
CHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGTLTYEAVGQLTALGLGQSSA
CEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHCCCEECCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKENMKKPVVGFIA
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEHHCCCCCCEEHEE
GVTAPPGKRMGHAGALISGGADTAQAKLEIMEACGIKVTKNPSEMGRLLKAML
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA