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The map label for this gene is sucC [H]

Identifier: 94309414

GI number: 94309414

Start: 498381

End: 499547

Strand: Direct

Name: sucC [H]

Synonym: Rmet_0469

Alternate gene names: 94309414

Gene position: 498381-499547 (Clockwise)

Preceding gene: 94309413

Following gene: 94309415

Centisome position: 12.69

GC content: 62.21

Gene sequence:

>1167_bases
ATGAATATCCATGAGTATCAAGGCAAGGAAATCCTGCGCAAATACAATGTGCCGGTTCCGCGCGGCATCCCTGCTTTCTC
GGTTGAAGAAGCCCTGAAGGCGGCTGAACAGCTCGGCGGCCCGGTGTGGGTCGTCAAGGCGCAGATCCACGCAGGCGGCC
GCGGCAAGGGCGGCGGCGTGAAGGTGGCCAAGAGCATCGACGAGGTGAAGACCTACGCCACCAACATTCTCGGCATGACG
CTGGTGACGCACCAGACCGGCCCGGAAGGCAAGAAGGTCAATCGCCTGCTGATCGAAGAAGGCGCTGACATCAAGAAGGA
ACTCTACGTTTCGCTGGTGGTGGACCGCGTGTCGCAGAAGGTGGCCCTGATGGCCTCGAGCGAAGGCGGCATGGACATCG
AGGAAGTCGCTGCCCACACCCCGGAAAAGATCCACACGCTGATCATCGAACCGTCGGAAGGCCTGAAGGATTCGGACGCT
GACGACATCGCCCGCAAGATCGGCGTGCCCGACGCCAGCGTTCCCCAGGCTCGCCAGGCCCTGCAAGGCCTGTACAAGGC
ATTCTGGGACACCGACGCCTCGCTGGCCGAAATCAACCCGCTGATCCTGACCGGCGACGGCAAGGTCGTTGCCCTGGACG
CCAAGTTCAACTTCGACTCGAACGCGCTGTTCCGTCACCCGGAAATCGTCGCGTACCGTGACCTGGACGAAGAAGACGCC
AACGAAATCGAGGCCTCGAAGTTCGATCTGGCCTACATCTCGCTGGACGGCAACATCGGCTGCCTGGTGAACGGCGCTGG
CCTGGCCATGGCCACGATGGACACCATCAAGCTGTTCGGTGGCGAGCCGGCCAACTTCCTCGACGTGGGTGGCGGCGCCA
CCACCGAGAAGGTGACCGAAGCCTTCAAGCTGATGCTGAAGAACCCGAACGTGCAGGCCATCCTGGTCAACATCTTCGGC
GGCATCATGCGTTGCGACGTGATCGCCGAAGGCGTGATCACCGCTTCGAAGGCCGTGCAGCTTGGCGTGCCGCTGGTCGT
CCGCATGAAGGGCACGAACGAAGAGCTGGGCCGCAAGATGCTGGCTGATTCCGGTCTGCCGATCATCTCGGCCGACACGA
TGGAAGAAGCCGCCCAGAAGGTCGTGGCCGCCGTCGCTGGCAAGTAA

Upstream 100 bases:

>100_bases
CGTCGGGCTGACTGTCACGGTCGGCCCCAGGAAAAGGCGAGAGCCCTTCGTCTCCTATCATTTTTCCCATCCCTTTACGC
CTACCCGAAAGGAAACACGC

Downstream 100 bases:

>100_bases
GGACAACTTTCGTTGCCGCCTGGCCGCAGCCGGGCGGGGCGACTAAAAGGACTAGCAAATGAGCATTCTGATCAACAAGG
ACACCAAGGTCATCACCCAG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNIHEYQGKEILRKYNVPVPRGIPAFSVEEALKAAEQLGGPVWVVKAQIHAGGRGKGGGVKVAKSIDEVKTYATNILGMT
LVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQKVALMASSEGGMDIEEVAAHTPEKIHTLIIEPSEGLKDSDA
DDIARKIGVPDASVPQARQALQGLYKAFWDTDASLAEINPLILTGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDA
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPNVQAILVNIFG
GIMRCDVIAEGVITASKAVQLGVPLVVRMKGTNEELGRKMLADSGLPIISADTMEEAAQKVVAAVAGK

Sequences:

>Translated_388_residues
MNIHEYQGKEILRKYNVPVPRGIPAFSVEEALKAAEQLGGPVWVVKAQIHAGGRGKGGGVKVAKSIDEVKTYATNILGMT
LVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQKVALMASSEGGMDIEEVAAHTPEKIHTLIIEPSEGLKDSDA
DDIARKIGVPDASVPQARQALQGLYKAFWDTDASLAEINPLILTGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDA
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPNVQAILVNIFG
GIMRCDVIAEGVITASKAVQLGVPLVVRMKGTNEELGRKMLADSGLPIISADTMEEAAQKVVAAVAGK
>Mature_388_residues
MNIHEYQGKEILRKYNVPVPRGIPAFSVEEALKAAEQLGGPVWVVKAQIHAGGRGKGGGVKVAKSIDEVKTYATNILGMT
LVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQKVALMASSEGGMDIEEVAAHTPEKIHTLIIEPSEGLKDSDA
DDIARKIGVPDASVPQARQALQGLYKAFWDTDASLAEINPLILTGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDA
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPNVQAILVNIFG
GIMRCDVIAEGVITASKAVQLGVPLVVRMKGTNEELGRKMLADSGLPIISADTMEEAAQKVVAAVAGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=47.5578406169666, Blast_Score=355, Evalue=6e-98,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=47.2584856396867, Blast_Score=331, Evalue=6e-91,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=47.3537604456825, Blast_Score=312, Evalue=3e-85,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=52.319587628866, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=44.4162436548223, Blast_Score=335, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=46.3917525773196, Blast_Score=332, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=47.1938775510204, Blast_Score=358, Evalue=1e-99,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=45.3400503778337, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=45.1948051948052, Blast_Score=321, Evalue=7e-88,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=45.1948051948052, Blast_Score=321, Evalue=7e-88,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=45.3367875647668, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=45.3367875647668, Blast_Score=320, Evalue=1e-87,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41345; Mature: 41345

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKEILRKYNVPVPRGIPAFSVEEALKAAEQLGGPVWVVKAQIHAGGRGKGGGV
CCCCHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCC
KVAKSIDEVKTYATNILGMTLVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQK
HHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VALMASSEGGMDIEEVAAHTPEKIHTLIIEPSEGLKDSDADDIARKIGVPDASVPQARQA
EEEEECCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWDTDASLAEINPLILTGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDA
HHHHHHHHHCCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCH
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
HHHCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPNVQAILVNIFGGIMRCDVIAEGVITASKAVQLGVPLVVRMKGTNEELGRKM
HHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
LADSGLPIISADTMEEAAQKVVAAVAGK
HHCCCCCEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQGKEILRKYNVPVPRGIPAFSVEEALKAAEQLGGPVWVVKAQIHAGGRGKGGGV
CCCCHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCC
KVAKSIDEVKTYATNILGMTLVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQK
HHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VALMASSEGGMDIEEVAAHTPEKIHTLIIEPSEGLKDSDADDIARKIGVPDASVPQARQA
EEEEECCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWDTDASLAEINPLILTGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDA
HHHHHHHHHCCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCH
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
HHHCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPNVQAILVNIFGGIMRCDVIAEGVITASKAVQLGVPLVVRMKGTNEELGRKM
HHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
LADSGLPIISADTMEEAAQKVVAAVAGK
HHCCCCCEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA