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The map label for this gene is tctD [H]

Identifier: 94309410

GI number: 94309410

Start: 494703

End: 495392

Strand: Reverse

Name: tctD [H]

Synonym: Rmet_0465

Alternate gene names: 94309410

Gene position: 495392-494703 (Counterclockwise)

Preceding gene: 94309420

Following gene: 94309409

Centisome position: 12.61

GC content: 65.65

Gene sequence:

>690_bases
ATGCGGATTCTTATCGCCGAAGATGACGATGTGCTGGCAGACGGGCTGACGCGCTCGCTGCGCCAGTCCGGCTATGCCGT
CGATCACGTTGCGAATGGCGTGGAAGCCGATTCGGCCCTGTCCACACAGTCGTTCGACCTGCTGATCCTCGATCTCGGCC
TGCCCCGCATGTCGGGGCTCGAGGTACTCAAGCGGCTGCGCGCGCGCAGCGCCATGGTGCCCGTGCTGATTCTGACTGCA
GCCGACAGCGTCGACGAACGCGTGAAGGGGCTGGACCTCGGCGCCGACGACTACATGGCCAAGCCGTTCGCGCTGTCCGA
ACTCGAGGCCCGGGTGCGCGCGCTGGTGCGCCGTGGCGCGGGCGGTGGCGCCACGCTGATGCGCCACGGGCCGCTCGCGT
TCGATCAGGTCGGCCGCATCGCCTATCTCAATGAACAGATGCTGGATCTCTCCGCGCGAGAGGTCGGTCTGCTCGAAATC
CTGCTCACGCGCAGCGGGCGGCTCGTATCGAAGGAGCAGCTCGTCGATCACCTGTGCGAATGGGGCGAGGAAGTCAGCAA
TAACGCAATCGAGGTGTATGTACACCGCCTGCGCAAAAAGATCGAGGTTGGCGGCATCCGCATCGCCACGGTGCGCGGGC
TGGGCTACTGCCTCGAGAAATACCAGCCGGCCGTGGCCGCGCATGGCTGA

Upstream 100 bases:

>100_bases
CGGAATGTCGGGTACTGTATAAAAAAACAGTATGCTTGGCAAGCCCCACCGGCACCGCGGCCGGCGGCCGGCTGTGGCCG
GCCACGAGGTGGAGACAATC

Downstream 100 bases:

>100_bases
CACCACGGGGGCTGATCGCGCATGAGCCTGCTGCGACTGCCGTGGCGACGCCGTTCCGCCGCGGGCCCCGCACGCGCGAC
GGACCCCACCCGGCCCACGC

Product: DNA-binding response regulator in two-component regulatory system with Rmet_0464

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MRILIAEDDDVLADGLTRSLRQSGYAVDHVANGVEADSALSTQSFDLLILDLGLPRMSGLEVLKRLRARSAMVPVLILTA
ADSVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGAGGGATLMRHGPLAFDQVGRIAYLNEQMLDLSAREVGLLEI
LLTRSGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKYQPAVAAHG

Sequences:

>Translated_229_residues
MRILIAEDDDVLADGLTRSLRQSGYAVDHVANGVEADSALSTQSFDLLILDLGLPRMSGLEVLKRLRARSAMVPVLILTA
ADSVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGAGGGATLMRHGPLAFDQVGRIAYLNEQMLDLSAREVGLLEI
LLTRSGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKYQPAVAAHG
>Mature_229_residues
MRILIAEDDDVLADGLTRSLRQSGYAVDHVANGVEADSALSTQSFDLLILDLGLPRMSGLEVLKRLRARSAMVPVLILTA
ADSVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGAGGGATLMRHGPLAFDQVGRIAYLNEQMLDLSAREVGLLEI
LLTRSGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKYQPAVAAHG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=45.4128440366972, Blast_Score=184, Evalue=3e-48,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=43.1192660550459, Blast_Score=173, Evalue=8e-45,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=38.2882882882883, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=36.6515837104072, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=35.9090909090909, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=35.1351351351351, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=34.2342342342342, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=34.4978165938865, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=32.7354260089686, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=32.579185520362, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=34.2105263157895, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=32.4675324675325, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.7610619469027, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=37.3913043478261, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=35.2380952380952, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788550, Length=172, Percent_Identity=28.4883720930233, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.037037037037, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=25.2136752136752, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=35.6435643564356, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24987; Mature: 24987

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIAEDDDVLADGLTRSLRQSGYAVDHVANGVEADSALSTQSFDLLILDLGLPRMSGL
CEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHH
EVLKRLRARSAMVPVLILTAADSVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGA
HHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCC
GGGATLMRHGPLAFDQVGRIAYLNEQMLDLSAREVGLLEILLTRSGRLVSKEQLVDHLCE
CCCCHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKYQPAVAAHG
HHHHHCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MRILIAEDDDVLADGLTRSLRQSGYAVDHVANGVEADSALSTQSFDLLILDLGLPRMSGL
CEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHH
EVLKRLRARSAMVPVLILTAADSVDERVKGLDLGADDYMAKPFALSELEARVRALVRRGA
HHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCC
GGGATLMRHGPLAFDQVGRIAYLNEQMLDLSAREVGLLEILLTRSGRLVSKEQLVDHLCE
CCCCHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEVGGIRIATVRGLGYCLEKYQPAVAAHG
HHHHHCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]