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The map label for this gene is qseC [H]

Identifier: 94309409

GI number: 94309409

Start: 493107

End: 494681

Strand: Reverse

Name: qseC [H]

Synonym: Rmet_0464

Alternate gene names: 94309409

Gene position: 494681-493107 (Counterclockwise)

Preceding gene: 94309410

Following gene: 94309408

Centisome position: 12.59

GC content: 66.48

Gene sequence:

>1575_bases
ATGAGCCTGCTGCGACTGCCGTGGCGACGCCGTTCCGCCGCGGGCCCCGCACGCGCGACGGACCCCACCCGGCCCACGCT
GGCCGATGCCGCGGCCGAAGACCAGGCGCTGGCCGACGCCCTGCCACACCTCGAGGAAACCTCGGCGCACCCTGCGCCCC
GCTCGCTGTTTGGCGAGATTCTCGACTGGATGCTGGCACCGCTTCTGCTGCTCTGGCCGATGAGCATCGCCGTCACATAC
CTCGTCGCCAAGTCGATTGCAAACGGGCCGTTCGACCGCGCGCTCGAAGCAAGCGCCATCGTGCTGTCGCAGCAGGTGCG
CGAGGTCAACGGCCGCGTCACGCTGCAGCTTCCACTGTCCGCGCGGGAAATCCTGCGCGCCGACGAGACCGACAATATCT
ACTACCAGGTGGTAGGCAAGCACGGCGAGTACGTGGCCGGCGATCACGACCTGCCGCTTCCGTCCGAGGACGAAGAGGGA
CATGCCGGGCTGGTATCGCTGCGCGACGATCGCGTGGCCGGCAACGATGTGCGTGTCGCCTATACCTACGTTGAACTGAA
AAACATCAGCGGCGCCCAGCCCGTGCTGGTGCAGGTGGCCGAGACGCTGGACAAGCGCGCGCGGCTGGCCAATGAAATCA
TCAAGGGCGTCATCCTGCCGCAGTTCGTGATCCTGCCGCTCGCGGTGGTGCTGGTGTGGTTTGGCCTCACGCGCGGGCTG
GCACCGCTGACCGCGATCCAGCAGCGCATCCGTGCGCGCAATCCCGGCGACACGAGCCCGATCGACGAGCGCGCGGCGCC
GCAGGAAATCACGCCGCTGGTAGCATCGTTCAACGACTTGCTGTCGCAACTCGAGCAGTCGGTGCAGACACAGAAACGCT
TCATTGCCGATGCCGCACACCAGATGAAGACACCGCTCGCGGGTCTGCGTATGCAGGCGGAACTGGCCCAGCGAGAGCAA
TCACCGGAGGAACTGCATCGGTCGCTGGCGCAGATCGCCGGCAGCTCCAAGCGCACCGCGCATCTGGTCACCCAGTTGCT
GTCGCTGGCACGCATGGAGAATCTGGCAGGGGTAGGCGGCATGACGCCGGTGAACCTGACCGCCCTGGCGCGCGACGTGG
TCAAGGATCTGCTGCCCCAGGCATGGGCGCGGCAGATCGACCTTGGCCTGGAAGGCGACGAGCATCCCGTGATGGTCACG
GGCAATCGCGTGATGCTGACGGAGATGCTCAACAACCTCGTCGACAACGCCATTCGCTACACGCCGCCCGGCGGGCATGC
CACGGTACGCGTCATCGCCGATGCATTCGAACCGTTCGCGTATCTCGATGTGGAAGACACGGGGCCGGGCATCCCCCCGA
GCGAGCGCGGACGCGTGATGGAGCGTTTCTATCGTGTGCTCGGCACCAACACCGAAGGCAGCGGACTGGGGCTGGCCATC
GTGCGCGAGATCGTGCAGCAGCACGGCGGCGAAATATCCATCGACGACAACGTGTACCAGACCGAGCCTCGCCTGGCCGG
CGCCCGGTTCCACGTGACGCTGCGCCGCGCGCCGCCGGAAGAGACCAACACATGA

Upstream 100 bases:

>100_bases
CGGCATCCGCATCGCCACGGTGCGCGGGCTGGGCTACTGCCTCGAGAAATACCAGCCGGCCGTGGCCGCGCATGGCTGAC
ACCACGGGGGCTGATCGCGC

Downstream 100 bases:

>100_bases
GGAAAGCCCCGCCCGACCGCATGACGCCGCGCGAGCGGCTTGCCTGGCGCCACAATCTGCGCTGGATCGCCGTGCTGCTG
GTGATCTGGTTCGTTGTGAC

Product: putative sensory histidine kinase in two-component regulatory system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MSLLRLPWRRRSAAGPARATDPTRPTLADAAAEDQALADALPHLEETSAHPAPRSLFGEILDWMLAPLLLLWPMSIAVTY
LVAKSIANGPFDRALEASAIVLSQQVREVNGRVTLQLPLSAREILRADETDNIYYQVVGKHGEYVAGDHDLPLPSEDEEG
HAGLVSLRDDRVAGNDVRVAYTYVELKNISGAQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLTRGL
APLTAIQQRIRARNPGDTSPIDERAAPQEITPLVASFNDLLSQLEQSVQTQKRFIADAAHQMKTPLAGLRMQAELAQREQ
SPEELHRSLAQIAGSSKRTAHLVTQLLSLARMENLAGVGGMTPVNLTALARDVVKDLLPQAWARQIDLGLEGDEHPVMVT
GNRVMLTEMLNNLVDNAIRYTPPGGHATVRVIADAFEPFAYLDVEDTGPGIPPSERGRVMERFYRVLGTNTEGSGLGLAI
VREIVQQHGGEISIDDNVYQTEPRLAGARFHVTLRRAPPEETNT

Sequences:

>Translated_524_residues
MSLLRLPWRRRSAAGPARATDPTRPTLADAAAEDQALADALPHLEETSAHPAPRSLFGEILDWMLAPLLLLWPMSIAVTY
LVAKSIANGPFDRALEASAIVLSQQVREVNGRVTLQLPLSAREILRADETDNIYYQVVGKHGEYVAGDHDLPLPSEDEEG
HAGLVSLRDDRVAGNDVRVAYTYVELKNISGAQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLTRGL
APLTAIQQRIRARNPGDTSPIDERAAPQEITPLVASFNDLLSQLEQSVQTQKRFIADAAHQMKTPLAGLRMQAELAQREQ
SPEELHRSLAQIAGSSKRTAHLVTQLLSLARMENLAGVGGMTPVNLTALARDVVKDLLPQAWARQIDLGLEGDEHPVMVT
GNRVMLTEMLNNLVDNAIRYTPPGGHATVRVIADAFEPFAYLDVEDTGPGIPPSERGRVMERFYRVLGTNTEGSGLGLAI
VREIVQQHGGEISIDDNVYQTEPRLAGARFHVTLRRAPPEETNT
>Mature_523_residues
SLLRLPWRRRSAAGPARATDPTRPTLADAAAEDQALADALPHLEETSAHPAPRSLFGEILDWMLAPLLLLWPMSIAVTYL
VAKSIANGPFDRALEASAIVLSQQVREVNGRVTLQLPLSAREILRADETDNIYYQVVGKHGEYVAGDHDLPLPSEDEEGH
AGLVSLRDDRVAGNDVRVAYTYVELKNISGAQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLTRGLA
PLTAIQQRIRARNPGDTSPIDERAAPQEITPLVASFNDLLSQLEQSVQTQKRFIADAAHQMKTPLAGLRMQAELAQREQS
PEELHRSLAQIAGSSKRTAHLVTQLLSLARMENLAGVGGMTPVNLTALARDVVKDLLPQAWARQIDLGLEGDEHPVMVTG
NRVMLTEMLNNLVDNAIRYTPPGGHATVRVIADAFEPFAYLDVEDTGPGIPPSERGRVMERFYRVLGTNTEGSGLGLAIV
REIVQQHGGEISIDDNVYQTEPRLAGARFHVTLRRAPPEETNT

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=371, Percent_Identity=31.266846361186, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI1786783, Length=331, Percent_Identity=30.2114803625378, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1790551, Length=309, Percent_Identity=30.7443365695793, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=30.5019305019305, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790861, Length=294, Percent_Identity=30.952380952381, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=33.6244541484716, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=28.3898305084746, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788279, Length=309, Percent_Identity=25.2427184466019, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=28.1632653061224, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=26.890756302521, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787374, Length=307, Percent_Identity=28.3387622149837, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=308, Percent_Identity=26.9480519480519, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=200, Percent_Identity=29, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=294, Percent_Identity=27.5510204081633, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=31.4285714285714, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=299, Percent_Identity=23.4113712374582, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=24.3801652892562, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=235, Percent_Identity=25.531914893617, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57315; Mature: 57184

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLRLPWRRRSAAGPARATDPTRPTLADAAAEDQALADALPHLEETSAHPAPRSLFGEI
CCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHH
LDWMLAPLLLLWPMSIAVTYLVAKSIANGPFDRALEASAIVLSQQVREVNGRVTLQLPLS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
AREILRADETDNIYYQVVGKHGEYVAGDHDLPLPSEDEEGHAGLVSLRDDRVAGNDVRVA
HHHHHCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEE
YTYVELKNISGAQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLTRGL
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APLTAIQQRIRARNPGDTSPIDERAAPQEITPLVASFNDLLSQLEQSVQTQKRFIADAAH
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMKTPLAGLRMQAELAQREQSPEELHRSLAQIAGSSKRTAHLVTQLLSLARMENLAGVGG
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
MTPVNLTALARDVVKDLLPQAWARQIDLGLEGDEHPVMVTGNRVMLTEMLNNLVDNAIRY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEHHHHHHHHHHHHCEEE
TPPGGHATVRVIADAFEPFAYLDVEDTGPGIPPSERGRVMERFYRVLGTNTEGSGLGLAI
CCCCCCEEHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHH
VREIVQQHGGEISIDDNVYQTEPRLAGARFHVTLRRAPPEETNT
HHHHHHHCCCEEEECCCCEECCCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
SLLRLPWRRRSAAGPARATDPTRPTLADAAAEDQALADALPHLEETSAHPAPRSLFGEI
CCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHH
LDWMLAPLLLLWPMSIAVTYLVAKSIANGPFDRALEASAIVLSQQVREVNGRVTLQLPLS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
AREILRADETDNIYYQVVGKHGEYVAGDHDLPLPSEDEEGHAGLVSLRDDRVAGNDVRVA
HHHHHCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEE
YTYVELKNISGAQPVLVQVAETLDKRARLANEIIKGVILPQFVILPLAVVLVWFGLTRGL
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APLTAIQQRIRARNPGDTSPIDERAAPQEITPLVASFNDLLSQLEQSVQTQKRFIADAAH
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMKTPLAGLRMQAELAQREQSPEELHRSLAQIAGSSKRTAHLVTQLLSLARMENLAGVGG
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
MTPVNLTALARDVVKDLLPQAWARQIDLGLEGDEHPVMVTGNRVMLTEMLNNLVDNAIRY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEHHHHHHHHHHHHCEEE
TPPGGHATVRVIADAFEPFAYLDVEDTGPGIPPSERGRVMERFYRVLGTNTEGSGLGLAI
CCCCCCEEHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHH
VREIVQQHGGEISIDDNVYQTEPRLAGARFHVTLRRAPPEETNT
HHHHHHHCCCEEEECCCCEECCCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]