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The map label for this gene is lnt [H]

Identifier: 94309394

GI number: 94309394

Start: 475924

End: 477456

Strand: Reverse

Name: lnt [H]

Synonym: Rmet_0449

Alternate gene names: 94309394

Gene position: 477456-475924 (Counterclockwise)

Preceding gene: 94309395

Following gene: 94309393

Centisome position: 12.15

GC content: 67.25

Gene sequence:

>1533_bases
ATGCAAGTCACGTCCCGCTCCGGCACCGTGTTCCGGCTGCTGATCGCGGCCGTCCTGGGCGTGGCCCATACACAAGCCTT
CGCACCGCACAACTGGTGGTGGCTGCAGATCCTGTCGCTGGCCGGACTCGTCGCACTGATCGCCGGCGCCCCACGCCCGC
GCGCCGCAGCGGCCACGGCCTATGCCTTCGGGCTGGGCTGGTTCCTGTCCGGCATCTGGTGGCTGTTCATCAGCATGCAC
GTCTACGGCGAGATGCCGTCGTGGATGGCCGGTCTGGCCGTGGTGCTGTTTGCCGGCTACCTGTCGATCTGGCCCGCCCT
GGCCGGCGCGGCCTGGCACTGGCTGACACAACGCGGCCGCAACGGCGTGCTCCCCGCGCTGGCGTTCGGCGCCACGTGGG
CGCTCTCCGAGTGGCTGCGCGGCGTGGTGTTCACCGGATTTCCGTGGCTCGGCAGTGGCTATCCCCACACGGACGGCCCG
CTGGCGGGTTTCGCGCCGCTGATCGGCGTCTATGGCATTTCCGCGCTGGCCGGGTTCATCGCGGCCTTGCTGGTGGCAGT
CGTCGGCGCCATCGGCCGCCAGCGAAAAGCCCGATCGGCGGTGCTCGCCGGCGGACTCGCGGTGGGCGTGCTGGCCTGCG
GCGCGGCGCTTGCGCCGATCCAGTACACCTCGCCCATCGGACAGCCGATCCATGTCCGGCTGCTGCAAGGCAATGTGGCC
CAGGACATCAAGTTCGAACCCGTGGGCATCGAGCGATCGCTGGAGCTTTACCGCGACCTGATCACCGAGGCGCCGGCCGA
TCTGGTGGTCACGCCGGAGACCGCATTCCCGGTAATCCTGCAGGAACTGCCGGTCGAGATCGCCCGTGCGGTGCGTACCT
TCATGGAAAAGACCGGCACCACGATCATCTTCGGCGCCGCCGGCGCCGATTCGCCGGTGGATTTCACCAACAGCGTGTTC
GCGATCGGCCCGGAACAGGATCAGCTCTACCGCTACAACAAGCACCATCTGGTGCCATTCGGCGAGTTCATCCCGTTCGG
CTTCCGCTGGTTCGTGGACATGATGAAAATGCCGCTGGGCGATTTCCGGCGCGGCACGCTGGACCAGCCGGCGGTTCCGG
TACGCGGCATTCATGTGGCACCGAATATCTGCTACGAGGATTTGTTCGGGGAAGAGATCGCGGCCACGCTGCGCCAGCAG
GCAACACCGGCCAACATGCTGGCCAACGTCACGAACCTGGCCTGGTTTGGCGACACGATCGCACTGGACCAGCACCTTCA
GATCTCGCGGATGCGCGCGCTGGAAATGCGCAGGCCCATGCTGCGTGCCACGAATACGGGCATGACCGCCGTGGTGGCAC
CGGATGGCACAGTGCAGGCAAAGCTGCCGACTTTCCAGGTGGGAACGCTGACCGCGACCGTGCAGGGCATGCAGGGCCTG
ACGCCTTACATCCGCTGGGGTAACGTGCCGGTGCTGATCGGCAGCCTGCTGGTGCTGTTGGTGGCCGCCCGCGCGCGACG
CGCGCGCGGGTAG

Upstream 100 bases:

>100_bases
AAGCATGACGCGCGTCGGCACGCCCGGCGCCGTGGGCACCCCTCGGGCCGGTTCGGCCGACTCACCAATGGGCGGCACGC
CGCCCTCCCCTTTTCAGACT

Downstream 100 bases:

>100_bases
GCGAAACGACGGTGCGAAGCCTCGGGGCTCAGCCGATCACCGAAGTGGCGATCGAGACGGCCGCAGCAGCGGCCATCACA
GCGATGGCGACGAGGTACGG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MQVTSRSGTVFRLLIAAVLGVAHTQAFAPHNWWWLQILSLAGLVALIAGAPRPRAAAATAYAFGLGWFLSGIWWLFISMH
VYGEMPSWMAGLAVVLFAGYLSIWPALAGAAWHWLTQRGRNGVLPALAFGATWALSEWLRGVVFTGFPWLGSGYPHTDGP
LAGFAPLIGVYGISALAGFIAALLVAVVGAIGRQRKARSAVLAGGLAVGVLACGAALAPIQYTSPIGQPIHVRLLQGNVA
QDIKFEPVGIERSLELYRDLITEAPADLVVTPETAFPVILQELPVEIARAVRTFMEKTGTTIIFGAAGADSPVDFTNSVF
AIGPEQDQLYRYNKHHLVPFGEFIPFGFRWFVDMMKMPLGDFRRGTLDQPAVPVRGIHVAPNICYEDLFGEEIAATLRQQ
ATPANMLANVTNLAWFGDTIALDQHLQISRMRALEMRRPMLRATNTGMTAVVAPDGTVQAKLPTFQVGTLTATVQGMQGL
TPYIRWGNVPVLIGSLLVLLVAARARRARG

Sequences:

>Translated_510_residues
MQVTSRSGTVFRLLIAAVLGVAHTQAFAPHNWWWLQILSLAGLVALIAGAPRPRAAAATAYAFGLGWFLSGIWWLFISMH
VYGEMPSWMAGLAVVLFAGYLSIWPALAGAAWHWLTQRGRNGVLPALAFGATWALSEWLRGVVFTGFPWLGSGYPHTDGP
LAGFAPLIGVYGISALAGFIAALLVAVVGAIGRQRKARSAVLAGGLAVGVLACGAALAPIQYTSPIGQPIHVRLLQGNVA
QDIKFEPVGIERSLELYRDLITEAPADLVVTPETAFPVILQELPVEIARAVRTFMEKTGTTIIFGAAGADSPVDFTNSVF
AIGPEQDQLYRYNKHHLVPFGEFIPFGFRWFVDMMKMPLGDFRRGTLDQPAVPVRGIHVAPNICYEDLFGEEIAATLRQQ
ATPANMLANVTNLAWFGDTIALDQHLQISRMRALEMRRPMLRATNTGMTAVVAPDGTVQAKLPTFQVGTLTATVQGMQGL
TPYIRWGNVPVLIGSLLVLLVAARARRARG
>Mature_510_residues
MQVTSRSGTVFRLLIAAVLGVAHTQAFAPHNWWWLQILSLAGLVALIAGAPRPRAAAATAYAFGLGWFLSGIWWLFISMH
VYGEMPSWMAGLAVVLFAGYLSIWPALAGAAWHWLTQRGRNGVLPALAFGATWALSEWLRGVVFTGFPWLGSGYPHTDGP
LAGFAPLIGVYGISALAGFIAALLVAVVGAIGRQRKARSAVLAGGLAVGVLACGAALAPIQYTSPIGQPIHVRLLQGNVA
QDIKFEPVGIERSLELYRDLITEAPADLVVTPETAFPVILQELPVEIARAVRTFMEKTGTTIIFGAAGADSPVDFTNSVF
AIGPEQDQLYRYNKHHLVPFGEFIPFGFRWFVDMMKMPLGDFRRGTLDQPAVPVRGIHVAPNICYEDLFGEEIAATLRQQ
ATPANMLANVTNLAWFGDTIALDQHLQISRMRALEMRRPMLRATNTGMTAVVAPDGTVQAKLPTFQVGTLTATVQGMQGL
TPYIRWGNVPVLIGSLLVLLVAARARRARG

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=519, Percent_Identity=35.8381502890173, Blast_Score=267, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 55054; Mature: 55054

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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CCHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]