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The map label for this gene is glyQ

Identifier: 94309393

GI number: 94309393

Start: 474487

End: 475440

Strand: Reverse

Name: glyQ

Synonym: Rmet_0448

Alternate gene names: 94309393

Gene position: 475440-474487 (Counterclockwise)

Preceding gene: 94309394

Following gene: 94309392

Centisome position: 12.1

GC content: 63.31

Gene sequence:

>954_bases
ATGCTGACCTTCCAACAAATGATTCTGACCCTGCAGGCCTACTGGGACCGGCAGGGTTGCGCGCTGTTGCAACCGATCGA
TCTGGAGGTCGGCGCCGGGACGTCGCACGTGCACACCTTCCTGCGCGCCATCGGCCCGGAACCGTGGCGTGCCGCATACG
TGCAACCGTCGCGCCGCCCCAAGGACGGCCGCTATGGCGAGAACCCCAACCGCCTGCAGCACTACTACCAGTACCAGGTG
GTGCTCAAGCCGGCGCCCGAGAACATTCTCGAGCTGTACCTCGGCTCGCTCGAGGCGCTGGGCCTTGACCTCAAGCAGAA
CGACATCCGCTTCGTCGAGGACGACTGGGAAAATCCGACGCTCGGCGCATGGGGCCTGGGCTGGGAAGTCTGGCTCAACG
GCATGGAAGTGACGCAGTTCACCTACTTCCAGCAGGTTGGCGGCATCGACTGCAAGCCGATCACCGGCGAAATCACCTAC
GGCATCGAGCGTCTGGCGATGTACCTGCAGAAGGTCGAGAACATCTACGACCTGGTCTGGACCGAATGGCAGGAAAACGG
CGAGACGCGCCGCCTGACCTACGGTGACGTGTACCACCAGAACGAAGTGGAACAGTCCACCTACAACTTCGAGCACAGCA
ACACGGAAATCCTGTTCCGCCATTTTGCCGAGCACGAGAGCGAAGCCAAGCGCCTGATGGGCGATACCGGCGAAAAGGCC
GAAGGCGCGCAGGAGAAGGCCGCTGGCACACGCCTGGCGCTGCCGGCCTATGAACAAGTGCTCAAGGCCGCCCACACCTT
CAACCTGCTGGACGCGCGCGGCGCGATCTCCGTGACCGAGCGTGCCGCCTATATCGGGCGAATCCGCAATCTGTCGCGCC
AGGTGGCGCAGGCCTACTACGACTCGCGGGAAGCACTTGGCTTCCCGATGTGCAAGACCGAGGCCCGCGCATGA

Upstream 100 bases:

>100_bases
CGCGGGGGGCGACCCAAAAACCCGATAGAATTCAAGGTTTGGCAAACCCCGCGCGAGACGGCTCGTGCACTTGCCCGCCA
GATTTCCTTTTCGTCTTCCT

Downstream 100 bases:

>100_bases
CACCCCATCTGCGCGGCGTCTGTGCGATCGTCGCGTTGGCCGTGTCCGCCGTGGCGGTGTTCGGCGGCAGCGCCGACGCC
CTGGCACGCACCGCATCCCC

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MLTFQQMILTLQAYWDRQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRPKDGRYGENPNRLQHYYQYQV
VLKPAPENILELYLGSLEALGLDLKQNDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEITY
GIERLAMYLQKVENIYDLVWTEWQENGETRRLTYGDVYHQNEVEQSTYNFEHSNTEILFRHFAEHESEAKRLMGDTGEKA
EGAQEKAAGTRLALPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRNLSRQVAQAYYDSREALGFPMCKTEARA

Sequences:

>Translated_317_residues
MLTFQQMILTLQAYWDRQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRPKDGRYGENPNRLQHYYQYQV
VLKPAPENILELYLGSLEALGLDLKQNDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEITY
GIERLAMYLQKVENIYDLVWTEWQENGETRRLTYGDVYHQNEVEQSTYNFEHSNTEILFRHFAEHESEAKRLMGDTGEKA
EGAQEKAAGTRLALPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRNLSRQVAQAYYDSREALGFPMCKTEARA
>Mature_317_residues
MLTFQQMILTLQAYWDRQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRPKDGRYGENPNRLQHYYQYQV
VLKPAPENILELYLGSLEALGLDLKQNDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEITY
GIERLAMYLQKVENIYDLVWTEWQENGETRRLTYGDVYHQNEVEQSTYNFEHSNTEILFRHFAEHESEAKRLMGDTGEKA
EGAQEKAAGTRLALPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRNLSRQVAQAYYDSREALGFPMCKTEARA

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=312, Percent_Identity=67.948717948718, Blast_Score=447, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_RALME (Q1LR92)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_582603.1
- ProteinModelPortal:   Q1LR92
- SMR:   Q1LR92
- STRING:   Q1LR92
- GeneID:   4037236
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_0448
- eggNOG:   COG0752
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- PhylomeDB:   Q1LR92
- ProtClustDB:   PRK09348
- BioCyc:   RMET266264:RMET_0448-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 36365; Mature: 36365

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFQQMILTLQAYWDRQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRP
CCCHHHHHHHHHHHHCCCCCEEECCCCEEECCCHHHHHHHHHHHCCCCCEEECCCCCCCC
KDGRYGENPNRLQHYYQYQVVLKPAPENILELYLGSLEALGLDLKQNDIRFVEDDWENPT
CCCCCCCCHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
LGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEITYGIERLAMYLQKVENIYDLVW
CCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TEWQENGETRRLTYGDVYHQNEVEQSTYNFEHSNTEILFRHFAEHESEAKRLMGDTGEKA
HHHHCCCCEEEEEECCHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
EGAQEKAAGTRLALPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRNLSRQVAQAYY
CCCHHHHCCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DSREALGFPMCKTEARA
CCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLTFQQMILTLQAYWDRQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRP
CCCHHHHHHHHHHHHCCCCCEEECCCCEEECCCHHHHHHHHHHHCCCCCEEECCCCCCCC
KDGRYGENPNRLQHYYQYQVVLKPAPENILELYLGSLEALGLDLKQNDIRFVEDDWENPT
CCCCCCCCHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
LGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEITYGIERLAMYLQKVENIYDLVW
CCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TEWQENGETRRLTYGDVYHQNEVEQSTYNFEHSNTEILFRHFAEHESEAKRLMGDTGEKA
HHHHCCCCEEEEEECCHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
EGAQEKAAGTRLALPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRNLSRQVAQAYY
CCCHHHHCCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DSREALGFPMCKTEARA
CCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA