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The map label for this gene is trpS [H]

Identifier: 94309385

GI number: 94309385

Start: 466712

End: 467740

Strand: Direct

Name: trpS [H]

Synonym: Rmet_0440

Alternate gene names: 94309385

Gene position: 466712-467740 (Clockwise)

Preceding gene: 94309384

Following gene: 335055492

Centisome position: 11.88

GC content: 64.33

Gene sequence:

>1029_bases
ATGACTGACCAGACCAACCCTGATAAGCGTCCCGTCATCCTGACTGGCGACCGTCCTACCGGCCCGCTTCACCTTGGCCA
TTTCGTCGGCTCCCTGAAGAGCCGCGTCACCCTGCAGGAGACGCACAAGCAGTACGTGCTGCTGGCCGATACCCAGGCGA
TGACCGATAACGCCCATGACCCCGACAAGGTGCGCCGCAACGTGCTCGAAGTCGCGCTCGACTACCTCGCCGTGGGCATC
GATCCGGCCAAGACCACGATCTCGGTGCAGTCGCACCTGCCGGCGCTGGCGGAACTGACGCTGATGTATCTGAACTTCGT
CACGGTATCGCGCCTGGAGCGCAACCCGACGATCAAGGAGGAAATCCAGGCGCGTGGCTTCGGCCGCGACATCCCGGCTG
GTTTCCTGTGCTACCCGGCTTCGCAGGCCGCCGACATCACCGGCTTCAAGGCCGTGCTGGTGCCCGTGGGCGAAGACCAG
GCACCGCTGATCGAGCAGACCAACGAGATCGTGCGTCGGGTCAACAATCAGGTGGGCCGCGAGGTGCTGCCCGAAGCCGC
CGCGCTTATCCCGAAGCATGGCCGTCTGCCGGGCGTGGATGGCAAGGCGAAGATGAGCAAGTCGCAGGGCAACGCGATTC
CGCTCGGCGCGTCGCCGGACCAGATTCGCGAAGCCGTGCACAAGATGTACACCGATCCGAACCACCTCAAGGTGTCCGAT
CCGGGCCAGGTGGAAGGCAATGTCGTGTTCACGTACCTCGACGCATTCGATCCGAATCCGGCTGAGGTGGAAGCGCTCAA
GGAGCACTACCGTCGTGGCGGACTGGGCGACATGGTGCTGAAGCGCCGCGTGGAAGGCGTCCTGCAGGAAATGCTGCGCC
CGATCCGCGAACGCCGCGAGCAGCTTGCCCAGGACCCGGGCTATGTGTTCGATATCCTGAAGAAGGGCACCGCCGAAGCC
CGCGAAATCACCCAGCAGACGCTGGACGAAGTGCGCGGCGCGCTGGGGATGTTCTCGTTCCCGCAGTGA

Upstream 100 bases:

>100_bases
GTATGTCGAGCTCGCGCGAATCGTCGGTGGCGCGGAGCCGCCCGCCCGCGTGGCCTGAGCCCCTTTTTATCCTGAATACC
CTGAAGTCCTTGCGACGCCC

Downstream 100 bases:

>100_bases
TTCGGCACTGATCGTTGTCGCCCTTGCCCGCTACGCGGGAGAGGGCGACAAACCGACGGCGTTCACTACGCCCGTCGATT
CACCAGCACAATCCCCCCCA

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTDQTNPDKRPVILTGDRPTGPLHLGHFVGSLKSRVTLQETHKQYVLLADTQAMTDNAHDPDKVRRNVLEVALDYLAVGI
DPAKTTISVQSHLPALAELTLMYLNFVTVSRLERNPTIKEEIQARGFGRDIPAGFLCYPASQAADITGFKAVLVPVGEDQ
APLIEQTNEIVRRVNNQVGREVLPEAAALIPKHGRLPGVDGKAKMSKSQGNAIPLGASPDQIREAVHKMYTDPNHLKVSD
PGQVEGNVVFTYLDAFDPNPAEVEALKEHYRRGGLGDMVLKRRVEGVLQEMLRPIRERREQLAQDPGYVFDILKKGTAEA
REITQQTLDEVRGALGMFSFPQ

Sequences:

>Translated_342_residues
MTDQTNPDKRPVILTGDRPTGPLHLGHFVGSLKSRVTLQETHKQYVLLADTQAMTDNAHDPDKVRRNVLEVALDYLAVGI
DPAKTTISVQSHLPALAELTLMYLNFVTVSRLERNPTIKEEIQARGFGRDIPAGFLCYPASQAADITGFKAVLVPVGEDQ
APLIEQTNEIVRRVNNQVGREVLPEAAALIPKHGRLPGVDGKAKMSKSQGNAIPLGASPDQIREAVHKMYTDPNHLKVSD
PGQVEGNVVFTYLDAFDPNPAEVEALKEHYRRGGLGDMVLKRRVEGVLQEMLRPIRERREQLAQDPGYVFDILKKGTAEA
REITQQTLDEVRGALGMFSFPQ
>Mature_341_residues
TDQTNPDKRPVILTGDRPTGPLHLGHFVGSLKSRVTLQETHKQYVLLADTQAMTDNAHDPDKVRRNVLEVALDYLAVGID
PAKTTISVQSHLPALAELTLMYLNFVTVSRLERNPTIKEEIQARGFGRDIPAGFLCYPASQAADITGFKAVLVPVGEDQA
PLIEQTNEIVRRVNNQVGREVLPEAAALIPKHGRLPGVDGKAKMSKSQGNAIPLGASPDQIREAVHKMYTDPNHLKVSDP
GQVEGNVVFTYLDAFDPNPAEVEALKEHYRRGGLGDMVLKRRVEGVLQEMLRPIRERREQLAQDPGYVFDILKKGTAEAR
EITQQTLDEVRGALGMFSFPQ

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=338, Percent_Identity=27.810650887574, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI41352700, Length=178, Percent_Identity=31.4606741573034, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1789786, Length=338, Percent_Identity=29.585798816568, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71982800, Length=350, Percent_Identity=30.5714285714286, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71982793, Length=361, Percent_Identity=30.1939058171745, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320474, Length=355, Percent_Identity=25.0704225352113, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=32.1321321321321, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37790; Mature: 37658

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQTNPDKRPVILTGDRPTGPLHLGHFVGSLKSRVTLQETHKQYVLLADTQAMTDNAHD
CCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCC
PDKVRRNVLEVALDYLAVGIDPAKTTISVQSHLPALAELTLMYLNFVTVSRLERNPTIKE
HHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
EIQARGFGRDIPAGFLCYPASQAADITGFKAVLVPVGEDQAPLIEQTNEIVRRVNNQVGR
HHHHCCCCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
EVLPEAAALIPKHGRLPGVDGKAKMSKSQGNAIPLGASPDQIREAVHKMYTDPNHLKVSD
HHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCCEEECC
PGQVEGNVVFTYLDAFDPNPAEVEALKEHYRRGGLGDMVLKRRVEGVLQEMLRPIRERRE
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAQDPGYVFDILKKGTAEAREITQQTLDEVRGALGMFSFPQ
HHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDQTNPDKRPVILTGDRPTGPLHLGHFVGSLKSRVTLQETHKQYVLLADTQAMTDNAHD
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCC
PDKVRRNVLEVALDYLAVGIDPAKTTISVQSHLPALAELTLMYLNFVTVSRLERNPTIKE
HHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
EIQARGFGRDIPAGFLCYPASQAADITGFKAVLVPVGEDQAPLIEQTNEIVRRVNNQVGR
HHHHCCCCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
EVLPEAAALIPKHGRLPGVDGKAKMSKSQGNAIPLGASPDQIREAVHKMYTDPNHLKVSD
HHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCCEEECC
PGQVEGNVVFTYLDAFDPNPAEVEALKEHYRRGGLGDMVLKRRVEGVLQEMLRPIRERRE
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAQDPGYVFDILKKGTAEAREITQQTLDEVRGALGMFSFPQ
HHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA