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The map label for this gene is pdxA [H]

Identifier: 94309383

GI number: 94309383

Start: 464753

End: 465829

Strand: Direct

Name: pdxA [H]

Synonym: Rmet_0438

Alternate gene names: 94309383

Gene position: 464753-465829 (Clockwise)

Preceding gene: 94309382

Following gene: 94309384

Centisome position: 11.83

GC content: 67.04

Gene sequence:

>1077_bases
ATGCCCGACCCCGCGCCACTCGACCTAGCGATCACGACCGGAGAACCGGCCGGCATCGGTCCCGATATCACGATCGGTGC
CCTGCTGCAGTTCGCCGCCAATCACGGCGGCAACGTCGGCCATGGGGGGGCGGTCCGCTTCCATGTGATCGGCGATGCGC
GTCTGCTCGATCAGCGTGCCGAGGCGCTCGGCGTGGCCCATGCGTGGGCACGTCGGATTGCCGACGGCGACGTGATCGTA
GAAGACATCGCGCTGGGCGTGCACTGCGAACCGGGGCGGCTCGATGCCCGCAATGGCCACTACGTGCTGGCGCTGCTGGA
TGCCGCCGTCGATGGCCTGCGGACGGGCCGCTATGCGGCCATGATTACCGCGCCGGTGCAGAAGAGCACGATCAATGATG
CTGGCGTGCCGTTTTCCGGGCATACCGAATATTTGGCCGAATGCGCCGGCGTGCCGCGTGTGGTAATGATGCTGGCCGGC
CCGCAGCCGGCGCATGACAACGCCATGCTGCGCGTGGCGCTGGCCACCACGCATCTGCCGCTGCGCGCGGTGCCCGACGC
GCTGAACATTCCGATGTTGGTCGAGACGCTGGCGATTGTCGATGCCGACCTGCGCCGGAATTTCGGCATCGCGCGTCCAC
GCATCCTGGTAACGGGACTGAACCCGCACGCGGGGGAGTCCGGTCATATGGGGCGCGAGGAAATCGACGTGATTTCTCCC
GCGCTCGAGCAGGCGCGCGATGCCGATATCGACGCGCGCGGCCCGTATCCCGCCGACACGCTGTTCCAGCCGCGCCATCT
GCGTGATGCCGACTGCGTGCTGGCGATGTACCATGACCAGGGCCTGGCACCCCTCAAGTACGGCACCTTTGGACACGGCG
TGAATATCACGCTGGGGCTACCCTTCATCCGCACATCGGTGGACCATGGGACCGCGCTCGACCTGGCCGGCACTGGCCGC
GCCGAGCACGGCAGCATGATCGAAGCCATCCGCTGTGCCATTACCATGGCCGGACATGCCAGCGGGCGCCACAGCAATGG
GCGCGCCGATAACGGCATCTCCAACGGCCAGCACTGA

Upstream 100 bases:

>100_bases
AAGCTGCGCGCCGCCTATGATGACTGGGTGCGCCAGCTCCGCAGCGCGGCGTATGTCGAATACCGGATCAACCGCCAGCG
CTGATGCGCTGGCCCGAACC

Downstream 100 bases:

>100_bases
CTTATGCGTTCAAACGTGCACCAGGGCCATGTGGCCCGCAAACGGTTCGGACAGAACTTCCTCGTCGACGACGGCATCAT
TCACGGCATCGTCAGCGCGA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MPDPAPLDLAITTGEPAGIGPDITIGALLQFAANHGGNVGHGGAVRFHVIGDARLLDQRAEALGVAHAWARRIADGDVIV
EDIALGVHCEPGRLDARNGHYVLALLDAAVDGLRTGRYAAMITAPVQKSTINDAGVPFSGHTEYLAECAGVPRVVMMLAG
PQPAHDNAMLRVALATTHLPLRAVPDALNIPMLVETLAIVDADLRRNFGIARPRILVTGLNPHAGESGHMGREEIDVISP
ALEQARDADIDARGPYPADTLFQPRHLRDADCVLAMYHDQGLAPLKYGTFGHGVNITLGLPFIRTSVDHGTALDLAGTGR
AEHGSMIEAIRCAITMAGHASGRHSNGRADNGISNGQH

Sequences:

>Translated_358_residues
MPDPAPLDLAITTGEPAGIGPDITIGALLQFAANHGGNVGHGGAVRFHVIGDARLLDQRAEALGVAHAWARRIADGDVIV
EDIALGVHCEPGRLDARNGHYVLALLDAAVDGLRTGRYAAMITAPVQKSTINDAGVPFSGHTEYLAECAGVPRVVMMLAG
PQPAHDNAMLRVALATTHLPLRAVPDALNIPMLVETLAIVDADLRRNFGIARPRILVTGLNPHAGESGHMGREEIDVISP
ALEQARDADIDARGPYPADTLFQPRHLRDADCVLAMYHDQGLAPLKYGTFGHGVNITLGLPFIRTSVDHGTALDLAGTGR
AEHGSMIEAIRCAITMAGHASGRHSNGRADNGISNGQH
>Mature_357_residues
PDPAPLDLAITTGEPAGIGPDITIGALLQFAANHGGNVGHGGAVRFHVIGDARLLDQRAEALGVAHAWARRIADGDVIVE
DIALGVHCEPGRLDARNGHYVLALLDAAVDGLRTGRYAAMITAPVQKSTINDAGVPFSGHTEYLAECAGVPRVVMMLAGP
QPAHDNAMLRVALATTHLPLRAVPDALNIPMLVETLAIVDADLRRNFGIARPRILVTGLNPHAGESGHMGREEIDVISPA
LEQARDADIDARGPYPADTLFQPRHLRDADCVLAMYHDQGLAPLKYGTFGHGVNITLGLPFIRTSVDHGTALDLAGTGRA
EHGSMIEAIRCAITMAGHASGRHSNGRADNGISNGQH

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=336, Percent_Identity=52.3809523809524, Blast_Score=308, Evalue=4e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 37660; Mature: 37529

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPAPLDLAITTGEPAGIGPDITIGALLQFAANHGGNVGHGGAVRFHVIGDARLLDQRA
CCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHH
EALGVAHAWARRIADGDVIVEDIALGVHCEPGRLDARNGHYVLALLDAAVDGLRTGRYAA
HHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHCCCCEEE
MITAPVQKSTINDAGVPFSGHTEYLAECAGVPRVVMMLAGPQPAHDNAMLRVALATTHLP
EEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEEECCCC
LRAVPDALNIPMLVETLAIVDADLRRNFGIARPRILVTGLNPHAGESGHMGREEIDVISP
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHH
ALEQARDADIDARGPYPADTLFQPRHLRDADCVLAMYHDQGLAPLKYGTFGHGVNITLGL
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCEEEEEEC
PFIRTSVDHGTALDLAGTGRAEHGSMIEAIRCAITMAGHASGRHSNGRADNGISNGQH
CHHEECCCCCCEEEECCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDPAPLDLAITTGEPAGIGPDITIGALLQFAANHGGNVGHGGAVRFHVIGDARLLDQRA
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHH
EALGVAHAWARRIADGDVIVEDIALGVHCEPGRLDARNGHYVLALLDAAVDGLRTGRYAA
HHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHCCCCEEE
MITAPVQKSTINDAGVPFSGHTEYLAECAGVPRVVMMLAGPQPAHDNAMLRVALATTHLP
EEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEEECCCC
LRAVPDALNIPMLVETLAIVDADLRRNFGIARPRILVTGLNPHAGESGHMGREEIDVISP
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHH
ALEQARDADIDARGPYPADTLFQPRHLRDADCVLAMYHDQGLAPLKYGTFGHGVNITLGL
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCCCEEEEEEC
PFIRTSVDHGTALDLAGTGRAEHGSMIEAIRCAITMAGHASGRHSNGRADNGISNGQH
CHHEECCCCCCEEEECCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA