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The map label for this gene is coxS [H]

Identifier: 94309310

GI number: 94309310

Start: 387324

End: 387845

Strand: Reverse

Name: coxS [H]

Synonym: Rmet_0365

Alternate gene names: 94309310

Gene position: 387845-387324 (Counterclockwise)

Preceding gene: 94309327

Following gene: 94309309

Centisome position: 9.87

GC content: 67.05

Gene sequence:

>522_bases
ATGCGTGCACCCACACAGGAGACAAGCATGGCGATTCCGATCCGCCTGACGGTCAATGGCAAGCCCGTTGACGCCCAGGT
CGAACCTCACACACTACTCGTCCAGTTCCTGCGCGAACACCTGCGCCTCACCGGCACGCACGTGGGCTGCGATACCGCCC
AGTGCGGCGCCTGCACCGTCCACCTGGATGGCCGCGCGGTGAAGTCCTGCAACGTGCTCGTGGTGCAGGCGGACGGCGGC
AGCGTGACGACGATCGAGGGCCTGGCCGTCAACGGCGAAATGCACCCCGTACAGCAAGCGTTCCGTGAATGCCACGGCCT
GCAATGCGGCTTCTGCACGCCGGGCATGGTGATGGCGGCCACGGCCCTGCTCAAGGACCGCCCCAACGCCGACGCGCAGG
CGATTCGCGACCAGCTCGAAGGCAACCTGTGCCGCTGTACCGGCTACCACAACATCGTGCGTGCGGTGCAGCAAGGTCAG
GCGGCCATGCAGGGCTCGGCGGCCGTGGCCAGCGCGGAATAA

Upstream 100 bases:

>100_bases
ACCCGGCAGCACCAATATCACGAAATAGCCGTCTCAACCAAACGGCAGTACCGCGTCGTGGCCAGTCCCGCGCAGTGAAT
CGGGATGGATGGAGCTGGCC

Downstream 100 bases:

>100_bases
GGAGACCGGCCATGAACGCACCCGAAAAGCTGATCGGTTCGCCGGTCCGCCGCAAGGAAGACTATCGCTTCCTGACCGGC
AACGGCCAGTACACCGACGA

Product: putative carbon monoxide dehydrogenase, 2Fe-2S iron-sulfur small subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MRAPTQETSMAIPIRLTVNGKPVDAQVEPHTLLVQFLREHLRLTGTHVGCDTAQCGACTVHLDGRAVKSCNVLVVQADGG
SVTTIEGLAVNGEMHPVQQAFRECHGLQCGFCTPGMVMAATALLKDRPNADAQAIRDQLEGNLCRCTGYHNIVRAVQQGQ
AAMQGSAAVASAE

Sequences:

>Translated_173_residues
MRAPTQETSMAIPIRLTVNGKPVDAQVEPHTLLVQFLREHLRLTGTHVGCDTAQCGACTVHLDGRAVKSCNVLVVQADGG
SVTTIEGLAVNGEMHPVQQAFRECHGLQCGFCTPGMVMAATALLKDRPNADAQAIRDQLEGNLCRCTGYHNIVRAVQQGQ
AAMQGSAAVASAE
>Mature_173_residues
MRAPTQETSMAIPIRLTVNGKPVDAQVEPHTLLVQFLREHLRLTGTHVGCDTAQCGACTVHLDGRAVKSCNVLVVQADGG
SVTTIEGLAVNGEMHPVQQAFRECHGLQCGFCTPGMVMAATALLKDRPNADAQAIRDQLEGNLCRCTGYHNIVRAVQQGQ
AAMQGSAAVASAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=39.4736842105263, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI91823271, Length=152, Percent_Identity=38.8157894736842, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1786480, Length=168, Percent_Identity=39.2857142857143, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1789232, Length=151, Percent_Identity=45.0331125827815, Blast_Score=123, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=45.6375838926174, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=40.9090909090909, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=38.961038961039, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17737937, Length=157, Percent_Identity=44.5859872611465, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=38.125, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=38.125, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24647201, Length=152, Percent_Identity=35.5263157894737, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24647199, Length=152, Percent_Identity=34.8684210526316, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647193, Length=159, Percent_Identity=36.4779874213836, Blast_Score=87, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 18303; Mature: 18303

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAPTQETSMAIPIRLTVNGKPVDAQVEPHTLLVQFLREHLRLTGTHVGCDTAQCGACTV
CCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
HLDGRAVKSCNVLVVQADGGSVTTIEGLAVNGEMHPVQQAFRECHGLQCGFCTPGMVMAA
EECCCEECCCCEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
TALLKDRPNADAQAIRDQLEGNLCRCTGYHNIVRAVQQGQAAMQGSAAVASAE
HHHHHCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MRAPTQETSMAIPIRLTVNGKPVDAQVEPHTLLVQFLREHLRLTGTHVGCDTAQCGACTV
CCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
HLDGRAVKSCNVLVVQADGGSVTTIEGLAVNGEMHPVQQAFRECHGLQCGFCTPGMVMAA
EECCCEECCCCEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
TALLKDRPNADAQAIRDQLEGNLCRCTGYHNIVRAVQQGQAAMQGSAAVASAE
HHHHHCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]