Click here to switch to the map view.

The map label for this gene is coxL [H]

Identifier: 94309309

GI number: 94309309

Start: 384934

End: 387312

Strand: Reverse

Name: coxL [H]

Synonym: Rmet_0364

Alternate gene names: 94309309

Gene position: 387312-384934 (Counterclockwise)

Preceding gene: 94309310

Following gene: 94309308

Centisome position: 9.86

GC content: 66.04

Gene sequence:

>2379_bases
ATGAACGCACCCGAAAAGCTGATCGGTTCGCCGGTCCGCCGCAAGGAAGACTATCGCTTCCTGACCGGCAACGGCCAGTA
CACCGACGATGTCGTCCTGCCGCACCAGAGCTACGGTTATTTCCTGCGCTCGCCGCATGCTCACGCGCGCATCAAGTCGA
TCGACACGTCCGAGGCGGCGGCCTCGCCCGGCGTGATCGCCGTGCTGACTGGCGATGACATGGCAGCCGACAAGGTCGGC
GGCCTGCCCTGCGGCTGGCTGATCCACAGCATCGACGGCTCGCCGATGAAAGAACCGCCCCACCCCTCGCTGGCGCACGG
CAAGGTGCGCCACGTGGGCGACCAGGTGGCGCTGGTCGTCGCAGAATCGCTCCAGCAGGCACGCGACGCCTCCGAGAAGA
TCGTTGTCGACTACGAGGAACTGCCAGCCGTGATCGGCCTGGCCAATGCCTCGTCGGCAGCTTCACTCGTCCACGACGAT
GTCCCCGCCAACACCTGCTACACGTGGGGCCACGGCGACAAGGCAGCCACGGACGCGGCATTCGCCAAGGCCGCTCACGT
GACCACGCTGCAGATCGTCAACAACCGGCTGATCCCGAACGCGATCGAACCGCGCGCGGTCAATGCCAGCTATACGCGCC
AGGATGACGGCTACACGGTCTACGTCGCCAACCAGAACCCGCACGTGGAGCGGCTGTTGATGGGGGCATTCGTGCTGGGC
CTGCCCGAGTCGCGCCTGCGCATCATCGCGCCGGACGTGGGCGGCGGCTTCGGCTCGAAGATCTTCCTCTACCCCGAGGA
CGTGGCACTGACCTGGGCATCGAAAAAGGTGGGACGTCCGATCAAGTGGACTGCGGAACGCTCCGAGTCCTTCCTGACCG
ACGCCCATGGTCGCGATCATGTGACCAAGGCTGAACTCGCGCTCGACGCCGACGGCAACTTCCTGGCGATGCGCGTGCAC
ACCATCGCCAACATGGGCGCGTACCTGTCGACGTTCGCCAGTAGCGTGCCGACGATCCTCTACGCGACACTCCTGGCCGG
CCAATACGCCACGCCGGCGATCTATGCCGAAGTCCACGCGGTGTTCACCAACACGTCCCCCGTCGATGCCTATCGCGGCG
CGGGACGCCCCGAGGCCACCTACGTCGTCGAGCGGCTGGTGGAAGCGGCCGCGCGCGAGACCAACGTCGATCCGGCCACG
CTGCGCCGCAAAAACTTCATCCGCACCTTCCCGTATGCCACTCCGGTGGGTCTGACCTACGACACCGGCGACTACGAGCC
CTGCCTGGCTCGCGCGGAGGAACTGGCCGACGTGGCGGGATTCCCGGCCCGGCGCGCGGAAGCGAAGCAACGCGGCAAGC
TGCGCGGGCTCGGCTACTCGTGCTACATCGAGGCCTGCGGGCTTGCGCCCTCGAATATCGCCGGAGCGCTGGGCGCGCGT
GCCGGGCTGTTCGAGGTGGGCGAGATCCGCGTGCATCCGACGGGCACCGTGACGGTCTTCACCGGATCGCACAGCCACGG
TCAAGGCCATGAAACCACGTTCGCGCAGATCGTGGCGGACCGCCTGGGCATCGCACTGGATGCCGTCGAGATCGTGCATG
GCGATACGGGCCGCGTGCCGTTCGGCATGGGGACCTATGGTTCCCGCTCACTGGCAGTGGGCGGCTCGGCGATCATGAAA
GCGCTCGACAAGATCGAGGCCAAGGCCAAGAAGATCGCCGCGCACCTGCTCGAGGCATCCGACGCCGACATCGAGTTCAA
GGACGGCGTGTTCCGCGTGGCCGGCACCGATCGCACCAAGACGTTCGGCGAGGTGGCGCTGACGGCATACGTGCCGCACA
ACTACCCGCTCGACAAGCTTGAGCCAGGCCTGAACGAGAACGCGTTCTACGATCCGACGAACTTCACGTATCCGTCCGGC
GCGTACATCTGCGAAGTCGAGGTCGATCCCGATACCGGCGAGTCGCACGTGGTCAAGTTCACCGCTGTGGATGACTTCGG
CAACGTGATCAACCCGATGATCGTGGAAGGCCAGGTACATGGCGGCATTGGCCAGGGGCTGGGTCAGGCGATGCTCGAAC
AGTGCGTCTACGACCCCGAGAGCGGCCAGCTCCTGACCGGTTCGTACATGGACTACGCGATGCCACGCGCCGGAGACCTG
CCCGACTTCACCGTCGAGACGTCCACCGGCACACCGTGCACGCACAATCCGCTCGGCGTGAAAGGCTGCGGCGAAGCCGG
CGCGATCGGCTCGCCACCGGCCTTCATCAACGCCATGGTCGACGCCTTGTCGCCGCTCGGCGTACACGATCTGCAGATGC
CTGCCACGCCGCATCGCGTGTGGCAAGCCATCCAGTCCGCGCAATCTGGCACCGCGTAA

Upstream 100 bases:

>100_bases
GCTGTACCGGCTACCACAACATCGTGCGTGCGGTGCAGCAAGGTCAGGCGGCCATGCAGGGCTCGGCGGCCGTGGCCAGC
GCGGAATAAGGAGACCGGCC

Downstream 100 bases:

>100_bases
CCGGGGAGAGCACAACATGTATGCATTTCAGTATGAACGTGCCGCCGACGCCAATGCCGCGGTGGCCAAGCTGAAGGCCG
ATGGCGACGCCAAGTTCCTG

Product: putative carbon-monoxide dehydrogenase, large subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MNAPEKLIGSPVRRKEDYRFLTGNGQYTDDVVLPHQSYGYFLRSPHAHARIKSIDTSEAAASPGVIAVLTGDDMAADKVG
GLPCGWLIHSIDGSPMKEPPHPSLAHGKVRHVGDQVALVVAESLQQARDASEKIVVDYEELPAVIGLANASSAASLVHDD
VPANTCYTWGHGDKAATDAAFAKAAHVTTLQIVNNRLIPNAIEPRAVNASYTRQDDGYTVYVANQNPHVERLLMGAFVLG
LPESRLRIIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDHVTKAELALDADGNFLAMRVH
TIANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVHAVFTNTSPVDAYRGAGRPEATYVVERLVEAAARETNVDPAT
LRRKNFIRTFPYATPVGLTYDTGDYEPCLARAEELADVAGFPARRAEAKQRGKLRGLGYSCYIEACGLAPSNIAGALGAR
AGLFEVGEIRVHPTGTVTVFTGSHSHGQGHETTFAQIVADRLGIALDAVEIVHGDTGRVPFGMGTYGSRSLAVGGSAIMK
ALDKIEAKAKKIAAHLLEASDADIEFKDGVFRVAGTDRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYPSG
AYICEVEVDPDTGESHVVKFTAVDDFGNVINPMIVEGQVHGGIGQGLGQAMLEQCVYDPESGQLLTGSYMDYAMPRAGDL
PDFTVETSTGTPCTHNPLGVKGCGEAGAIGSPPAFINAMVDALSPLGVHDLQMPATPHRVWQAIQSAQSGTA

Sequences:

>Translated_792_residues
MNAPEKLIGSPVRRKEDYRFLTGNGQYTDDVVLPHQSYGYFLRSPHAHARIKSIDTSEAAASPGVIAVLTGDDMAADKVG
GLPCGWLIHSIDGSPMKEPPHPSLAHGKVRHVGDQVALVVAESLQQARDASEKIVVDYEELPAVIGLANASSAASLVHDD
VPANTCYTWGHGDKAATDAAFAKAAHVTTLQIVNNRLIPNAIEPRAVNASYTRQDDGYTVYVANQNPHVERLLMGAFVLG
LPESRLRIIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDHVTKAELALDADGNFLAMRVH
TIANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVHAVFTNTSPVDAYRGAGRPEATYVVERLVEAAARETNVDPAT
LRRKNFIRTFPYATPVGLTYDTGDYEPCLARAEELADVAGFPARRAEAKQRGKLRGLGYSCYIEACGLAPSNIAGALGAR
AGLFEVGEIRVHPTGTVTVFTGSHSHGQGHETTFAQIVADRLGIALDAVEIVHGDTGRVPFGMGTYGSRSLAVGGSAIMK
ALDKIEAKAKKIAAHLLEASDADIEFKDGVFRVAGTDRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYPSG
AYICEVEVDPDTGESHVVKFTAVDDFGNVINPMIVEGQVHGGIGQGLGQAMLEQCVYDPESGQLLTGSYMDYAMPRAGDL
PDFTVETSTGTPCTHNPLGVKGCGEAGAIGSPPAFINAMVDALSPLGVHDLQMPATPHRVWQAIQSAQSGTA
>Mature_792_residues
MNAPEKLIGSPVRRKEDYRFLTGNGQYTDDVVLPHQSYGYFLRSPHAHARIKSIDTSEAAASPGVIAVLTGDDMAADKVG
GLPCGWLIHSIDGSPMKEPPHPSLAHGKVRHVGDQVALVVAESLQQARDASEKIVVDYEELPAVIGLANASSAASLVHDD
VPANTCYTWGHGDKAATDAAFAKAAHVTTLQIVNNRLIPNAIEPRAVNASYTRQDDGYTVYVANQNPHVERLLMGAFVLG
LPESRLRIIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDHVTKAELALDADGNFLAMRVH
TIANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVHAVFTNTSPVDAYRGAGRPEATYVVERLVEAAARETNVDPAT
LRRKNFIRTFPYATPVGLTYDTGDYEPCLARAEELADVAGFPARRAEAKQRGKLRGLGYSCYIEACGLAPSNIAGALGAR
AGLFEVGEIRVHPTGTVTVFTGSHSHGQGHETTFAQIVADRLGIALDAVEIVHGDTGRVPFGMGTYGSRSLAVGGSAIMK
ALDKIEAKAKKIAAHLLEASDADIEFKDGVFRVAGTDRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYPSG
AYICEVEVDPDTGESHVVKFTAVDDFGNVINPMIVEGQVHGGIGQGLGQAMLEQCVYDPESGQLLTGSYMDYAMPRAGDL
PDFTVETSTGTPCTHNPLGVKGCGEAGAIGSPPAFINAMVDALSPLGVHDLQMPATPHRVWQAIQSAQSGTA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=809, Percent_Identity=24.9690976514215, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI91823271, Length=780, Percent_Identity=25.5128205128205, Blast_Score=158, Evalue=2e-38,
Organism=Escherichia coli, GI1789230, Length=780, Percent_Identity=27.3076923076923, Blast_Score=238, Evalue=2e-63,
Organism=Escherichia coli, GI1789246, Length=842, Percent_Identity=26.1282660332542, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI1786478, Length=769, Percent_Identity=25.2275682704811, Blast_Score=137, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17540638, Length=827, Percent_Identity=24.0628778718259, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17539860, Length=823, Percent_Identity=22.8432563791009, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32566215, Length=584, Percent_Identity=24.1438356164384, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17737937, Length=765, Percent_Identity=26.2745098039216, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24647199, Length=769, Percent_Identity=23.667100130039, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24647195, Length=807, Percent_Identity=22.9244114002478, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647197, Length=570, Percent_Identity=25.2631578947368, Blast_Score=87, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84411; Mature: 84411

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPEKLIGSPVRRKEDYRFLTGNGQYTDDVVLPHQSYGYFLRSPHAHARIKSIDTSEAA
CCCCHHHHCCCCCCCCCCEEEECCCCCCCCEECCCCCCCCEEECCCCHHEEECCCCHHHC
ASPGVIAVLTGDDMAADKVGGLPCGWLIHSIDGSPMKEPPHPSLAHGKVRHVGDQVALVV
CCCCEEEEEECCCCCHHHCCCCCHHHEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHH
AESLQQARDASEKIVVDYEELPAVIGLANASSAASLVHDDVPANTCYTWGHGDKAATDAA
HHHHHHHHCCCCEEEEEHHHCCCEEEECCCCHHHHHHHCCCCCCCEEEECCCCCHHHHHH
FAKAAHVTTLQIVNNRLIPNAIEPRAVNASYTRQDDGYTVYVANQNPHVERLLMGAFVLG
HHHHHHHEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHC
LPESRLRIIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDH
CCCCCEEEEECCCCCCCCCEEEEEECCEEEEECHHHCCCCEEEEHHHHHHHHHCCCCCCC
VTKAELALDADGNFLAMRVHTIANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVHA
CEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEE
VFTNTSPVDAYRGAGRPEATYVVERLVEAAARETNVDPATLRRKNFIRTFPYATPVGLTY
EEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEE
DTGDYEPCLARAEELADVAGFPARRAEAKQRGKLRGLGYSCYIEACGLAPSNIAGALGAR
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCC
AGLFEVGEIRVHPTGTVTVFTGSHSHGQGHETTFAQIVADRLGIALDAVEIVHGDTGRVP
CCCEEECEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCHHEEEEEEEECCCCCCC
FGMGTYGSRSLAVGGSAIMKALDKIEAKAKKIAAHLLEASDADIEFKDGVFRVAGTDRTK
CCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCC
TFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYPSGAYICEVEVDPDTGESHVVKF
CCCEEEEEEEECCCCCHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCEEEEE
TAVDDFGNVINPMIVEGQVHGGIGQGLGQAMLEQCVYDPESGQLLTGSYMDYAMPRAGDL
EEECHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHCCCCCCCC
PDFTVETSTGTPCTHNPLGVKGCGEAGAIGSPPAFINAMVDALSPLGVHDLQMPATPHRV
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHH
WQAIQSAQSGTA
HHHHHHHCCCCC
>Mature Secondary Structure
MNAPEKLIGSPVRRKEDYRFLTGNGQYTDDVVLPHQSYGYFLRSPHAHARIKSIDTSEAA
CCCCHHHHCCCCCCCCCCEEEECCCCCCCCEECCCCCCCCEEECCCCHHEEECCCCHHHC
ASPGVIAVLTGDDMAADKVGGLPCGWLIHSIDGSPMKEPPHPSLAHGKVRHVGDQVALVV
CCCCEEEEEECCCCCHHHCCCCCHHHEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHH
AESLQQARDASEKIVVDYEELPAVIGLANASSAASLVHDDVPANTCYTWGHGDKAATDAA
HHHHHHHHCCCCEEEEEHHHCCCEEEECCCCHHHHHHHCCCCCCCEEEECCCCCHHHHHH
FAKAAHVTTLQIVNNRLIPNAIEPRAVNASYTRQDDGYTVYVANQNPHVERLLMGAFVLG
HHHHHHHEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHC
LPESRLRIIAPDVGGGFGSKIFLYPEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDH
CCCCCEEEEECCCCCCCCCEEEEEECCEEEEECHHHCCCCEEEEHHHHHHHHHCCCCCCC
VTKAELALDADGNFLAMRVHTIANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVHA
CEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEE
VFTNTSPVDAYRGAGRPEATYVVERLVEAAARETNVDPATLRRKNFIRTFPYATPVGLTY
EEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEE
DTGDYEPCLARAEELADVAGFPARRAEAKQRGKLRGLGYSCYIEACGLAPSNIAGALGAR
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCC
AGLFEVGEIRVHPTGTVTVFTGSHSHGQGHETTFAQIVADRLGIALDAVEIVHGDTGRVP
CCCEEECEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCHHEEEEEEEECCCCCCC
FGMGTYGSRSLAVGGSAIMKALDKIEAKAKKIAAHLLEASDADIEFKDGVFRVAGTDRTK
CCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCC
TFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYPSGAYICEVEVDPDTGESHVVKF
CCCEEEEEEEECCCCCHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCEEEEE
TAVDDFGNVINPMIVEGQVHGGIGQGLGQAMLEQCVYDPESGQLLTGSYMDYAMPRAGDL
EEECHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHCCCCCCCC
PDFTVETSTGTPCTHNPLGVKGCGEAGAIGSPPAFINAMVDALSPLGVHDLQMPATPHRV
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHH
WQAIQSAQSGTA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]