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The map label for this gene is grxC [H]

Identifier: 94309197

GI number: 94309197

Start: 269216

End: 269473

Strand: Direct

Name: grxC [H]

Synonym: Rmet_0252

Alternate gene names: 94309197

Gene position: 269216-269473 (Clockwise)

Preceding gene: 335055483

Following gene: 94309198

Centisome position: 6.85

GC content: 65.12

Gene sequence:

>258_bases
ATGGCCCGCGTCGTCATGTACAGCACGGTGGTGTGCCCCTACTGCCAGATGGCAGAGCGTCTGCTCAAGCAGCGGGGCGT
CGAGGCGATCGAGAAAATCCTGATCGACCGCGAACCCGGCAAGCGCGAGGAAATGATGACTCGCACCGGCCGCCGGACCG
TGCCGCAGATCTATATCGACGAGACACACGTGGGTGGATTCGACGACTTGTCCGCGCTGGACCGTCAGGGCGGCCTGGTG
CCGCTGCTGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGACTTCCGGTCATCAAGTAAGCCCATTTATCGAAGTATTCGCGGCGCGGACCGCCCCGGGCGGTCCGCGCCGTTGTTT
TGAATTCAAGGAGATTTCGC

Downstream 100 bases:

>100_bases
GCCCCGGCCCCGGCGGTTTCCCAGCGAGATCAACGACCTATCCGATTGACGCCGGCCCCGGGTGAATTCGCCCACGGCGT
CATGTACCATATGCGCTTTC

Product: glutaredoxin 3

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MARVVMYSTVVCPYCQMAERLLKQRGVEAIEKILIDREPGKREEMMTRTGRRTVPQIYIDETHVGGFDDLSALDRQGGLV
PLLAA

Sequences:

>Translated_85_residues
MARVVMYSTVVCPYCQMAERLLKQRGVEAIEKILIDREPGKREEMMTRTGRRTVPQIYIDETHVGGFDDLSALDRQGGLV
PLLAA
>Mature_84_residues
ARVVMYSTVVCPYCQMAERLLKQRGVEAIEKILIDREPGKREEMMTRTGRRTVPQIYIDETHVGGFDDLSALDRQGGLVP
LLAA

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=54.2168674698795, Blast_Score=94, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9594; Mature: 9463

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVVMYSTVVCPYCQMAERLLKQRGVEAIEKILIDREPGKREEMMTRTGRRTVPQIYID
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEC
ETHVGGFDDLSALDRQGGLVPLLAA
CCCCCCCHHHHHHHHCCCEEEECCC
>Mature Secondary Structure 
ARVVMYSTVVCPYCQMAERLLKQRGVEAIEKILIDREPGKREEMMTRTGRRTVPQIYID
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEC
ETHVGGFDDLSALDRQGGLVPLLAA
CCCCCCCHHHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]