| Definition | Cupriavidus metallidurans CH34 chromosome, complete genome. |
|---|---|
| Accession | NC_007973 |
| Length | 3,928,089 |
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The map label for this gene is livF8 [H]
Identifier: 94309164
GI number: 94309164
Start: 233224
End: 234039
Strand: Direct
Name: livF8 [H]
Synonym: Rmet_0219
Alternate gene names: 94309164
Gene position: 233224-234039 (Clockwise)
Preceding gene: 94309163
Following gene: 94309165
Centisome position: 5.94
GC content: 63.48
Gene sequence:
>816_bases ATGACCCTTCTATCCGTCAACAACATCGAAGTCATCTACGACCACGTGATCCTCGTGCTCAAGGGCGTGTCGCTCGAAGT GCCTGAGGGTCGCATCGTGGCGTTGCTGGGCGCCAATGGCGCGGGCAAGACCACCACGCTCAAGGCGATCTCGAATCTGC TGCATGCGGAGCGTGGCGATGTCACCAAGGGCTCGATCGAATATCGCGGGCAGCGCGTGGACCAGCTCACGCCAAACGAT CTGGTCAAGCGCGGCGTGATCCAGGTCATGGAGGGGCGCCACTGCTTCGCGCACCTGACGATCGAGGAAAACCTGCTGAC GGGCGCCTATACCCGCGGGCTGTCGCGCGGCCAGACACGCGATGAACTTGAGAAGATCTACGCGTACTTTCCGCGCCTGA AGACGCGCCGCAAATCGCAGGCAGGCTATACGTCCGGCGGCGAGCAGCAGATGTGCGCGATCGGGCGGGCCATGATGGCC AAGCCGGCGATGATCCTGCTCGACGAGCCGTCGATGGGCCTGGCGCCGCAGATCGTCGAGGAGATCTTCGAGATCGTGCG TGACCTGAATACCCGCGAGCGCGTCAGCTTTCTGCTGGCCGAGCAGAACACGATGGTGGCGCTGCGCCATGCCGACTACG GTTACATCCTCGAAAACGGCCGCGTGGTGATGGATGGCGATGCGGAATCGCTGCGCACCAACGAGGACGTCAAGGAGTTC TACCTGGGCGTGGCCGCCAACGATGCGGATGGTGCCGCGCGCAAGTCGTTCCGCGATGTGAAGAGCTACCGCCGCCGCAA GCGCTGGCTGGCGTGA
Upstream 100 bases:
>100_bases AGGAAAAGGGCATCACGCCGGCTTGCATGAAGTCGTAGGCGTTGCCTTTCCCCCGCTCCCACTCGTGGGGGCGGGGAGCA AAACGATCTGGGATGCGGAC
Downstream 100 bases:
>100_bases ACACAAGACAGACCATGGCTGCTGATCCTGTTGAATATTTCGATGCCCTCGAGACACGCAATCCGGCCGAGCGCGAGGCG GCGCTGTTTGCCGCCCTGGT
Product: leucine/isoleucine/valine ABC transporter ATP-binding protein
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 271; Mature: 270
Protein sequence:
>271_residues MTLLSVNNIEVIYDHVILVLKGVSLEVPEGRIVALLGANGAGKTTTLKAISNLLHAERGDVTKGSIEYRGQRVDQLTPND LVKRGVIQVMEGRHCFAHLTIEENLLTGAYTRGLSRGQTRDELEKIYAYFPRLKTRRKSQAGYTSGGEQQMCAIGRAMMA KPAMILLDEPSMGLAPQIVEEIFEIVRDLNTRERVSFLLAEQNTMVALRHADYGYILENGRVVMDGDAESLRTNEDVKEF YLGVAANDADGAARKSFRDVKSYRRRKRWLA
Sequences:
>Translated_271_residues MTLLSVNNIEVIYDHVILVLKGVSLEVPEGRIVALLGANGAGKTTTLKAISNLLHAERGDVTKGSIEYRGQRVDQLTPND LVKRGVIQVMEGRHCFAHLTIEENLLTGAYTRGLSRGQTRDELEKIYAYFPRLKTRRKSQAGYTSGGEQQMCAIGRAMMA KPAMILLDEPSMGLAPQIVEEIFEIVRDLNTRERVSFLLAEQNTMVALRHADYGYILENGRVVMDGDAESLRTNEDVKEF YLGVAANDADGAARKSFRDVKSYRRRKRWLA >Mature_270_residues TLLSVNNIEVIYDHVILVLKGVSLEVPEGRIVALLGANGAGKTTTLKAISNLLHAERGDVTKGSIEYRGQRVDQLTPNDL VKRGVIQVMEGRHCFAHLTIEENLLTGAYTRGLSRGQTRDELEKIYAYFPRLKTRRKSQAGYTSGGEQQMCAIGRAMMAK PAMILLDEPSMGLAPQIVEEIFEIVRDLNTRERVSFLLAEQNTMVALRHADYGYILENGRVVMDGDAESLRTNEDVKEFY LGVAANDADGAARKSFRDVKSYRRRKRWLA
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI42490749, Length=235, Percent_Identity=28.5106382978723, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI148612844, Length=230, Percent_Identity=25.2173913043478, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI255708477, Length=230, Percent_Identity=24.7826086956522, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI9961250, Length=229, Percent_Identity=30.5676855895196, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI9961252, Length=229, Percent_Identity=30.5676855895196, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI4505771, Length=229, Percent_Identity=30.5676855895196, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI153792144, Length=216, Percent_Identity=25.462962962963, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI21536376, Length=248, Percent_Identity=25.4032258064516, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI42741659, Length=223, Percent_Identity=29.5964125560538, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI27477115, Length=213, Percent_Identity=27.6995305164319, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI27436953, Length=213, Percent_Identity=25.3521126760563, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI46592971, Length=215, Percent_Identity=25.1162790697674, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI46592956, Length=215, Percent_Identity=25.1162790697674, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592964, Length=215, Percent_Identity=25.1162790697674, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592915, Length=215, Percent_Identity=25.1162790697674, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592898, Length=215, Percent_Identity=25.1162790697674, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592978, Length=215, Percent_Identity=25.1162790697674, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI105990541, Length=204, Percent_Identity=28.4313725490196, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI27262624, Length=157, Percent_Identity=28.6624203821656, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI27262626, Length=157, Percent_Identity=28.6624203821656, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI45446740, Length=185, Percent_Identity=27.5675675675676, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI47078218, Length=185, Percent_Identity=27.5675675675676, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI116734710, Length=157, Percent_Identity=31.2101910828025, Blast_Score=68, Evalue=1e-11, Organism=Escherichia coli, GI87082268, Length=245, Percent_Identity=42.0408163265306, Blast_Score=176, Evalue=2e-45, Organism=Escherichia coli, GI1789864, Length=258, Percent_Identity=29.4573643410853, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI1787089, Length=218, Percent_Identity=32.5688073394495, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1788225, Length=261, Percent_Identity=30.6513409961686, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1787029, Length=219, Percent_Identity=28.7671232876712, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI87082267, Length=220, Percent_Identity=28.1818181818182, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1789593, Length=226, Percent_Identity=30.5309734513274, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI1787712, Length=220, Percent_Identity=28.6363636363636, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1788450, Length=252, Percent_Identity=26.984126984127, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787792, Length=228, Percent_Identity=28.5087719298246, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1786398, Length=226, Percent_Identity=27.4336283185841, Blast_Score=85, Evalue=7e-18, Organism=Escherichia coli, GI1789672, Length=183, Percent_Identity=28.9617486338798, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1788761, Length=233, Percent_Identity=30.0429184549356, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI87081709, Length=213, Percent_Identity=25.3521126760563, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786253, Length=251, Percent_Identity=24.7011952191235, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1790544, Length=241, Percent_Identity=29.045643153527, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787105, Length=198, Percent_Identity=32.3232323232323, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1790467, Length=227, Percent_Identity=28.1938325991189, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1788644, Length=233, Percent_Identity=28.3261802575107, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI87081791, Length=232, Percent_Identity=25.4310344827586, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1786872, Length=231, Percent_Identity=26.8398268398268, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789586, Length=239, Percent_Identity=25.1046025104602, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1788506, Length=246, Percent_Identity=27.2357723577236, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI48995001, Length=211, Percent_Identity=30.3317535545024, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI1786319, Length=246, Percent_Identity=26.0162601626016, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1789032, Length=234, Percent_Identity=23.9316239316239, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1790190, Length=198, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI48994943, Length=270, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1787972, Length=235, Percent_Identity=25.9574468085106, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI87081834, Length=198, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1787370, Length=208, Percent_Identity=25.4807692307692, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1786703, Length=212, Percent_Identity=27.3584905660377, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1786803, Length=226, Percent_Identity=23.8938053097345, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI48994997, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1788472, Length=180, Percent_Identity=27.2222222222222, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1789873, Length=207, Percent_Identity=27.536231884058, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1790525, Length=230, Percent_Identity=26.0869565217391, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1790162, Length=242, Percent_Identity=22.3140495867769, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1788897, Length=191, Percent_Identity=28.2722513089005, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1790739, Length=223, Percent_Identity=26.457399103139, Blast_Score=62, Evalue=4e-11, Organism=Escherichia coli, GI1787112, Length=211, Percent_Identity=28.9099526066351, Blast_Score=62, Evalue=4e-11, Organism=Escherichia coli, GI1787164, Length=211, Percent_Identity=24.1706161137441, Blast_Score=61, Evalue=9e-11, Organism=Caenorhabditis elegans, GI25146777, Length=237, Percent_Identity=27.0042194092827, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI71996809, Length=232, Percent_Identity=28.8793103448276, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193211017, Length=232, Percent_Identity=28.448275862069, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193211015, Length=232, Percent_Identity=28.448275862069, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17541710, Length=279, Percent_Identity=27.2401433691756, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI115533608, Length=236, Percent_Identity=25.8474576271186, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI212646699, Length=223, Percent_Identity=27.3542600896861, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17558664, Length=238, Percent_Identity=26.890756302521, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI71996550, Length=213, Percent_Identity=26.7605633802817, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17567269, Length=223, Percent_Identity=26.9058295964126, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17567265, Length=223, Percent_Identity=26.9058295964126, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193209708, Length=219, Percent_Identity=26.4840182648402, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI115535101, Length=223, Percent_Identity=26.0089686098655, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17569143, Length=227, Percent_Identity=28.6343612334802, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71984940, Length=216, Percent_Identity=25, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI71992285, Length=239, Percent_Identity=27.6150627615063, Blast_Score=64, Evalue=1e-10, Organism=Drosophila melanogaster, GI85726357, Length=224, Percent_Identity=26.7857142857143, Blast_Score=75, Evalue=7e-14, Organism=Drosophila melanogaster, GI28574150, Length=194, Percent_Identity=29.3814432989691, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI116007328, Length=194, Percent_Identity=29.3814432989691, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24641565, Length=222, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21357907, Length=237, Percent_Identity=26.1603375527426, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI28574533, Length=225, Percent_Identity=25.7777777777778, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 30317; Mature: 30186
Theoretical pI: Translated: 8.95; Mature: 8.95
Prosite motif: PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTLLSVNNIEVIYDHVILVLKGVSLEVPEGRIVALLGANGAGKTTTLKAISNLLHAERGD CEEEECCCHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCC VTKGSIEYRGQRVDQLTPNDLVKRGVIQVMEGRHCFAHLTIEENLLTGAYTRGLSRGQTR CCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCCCCCH DELEKIYAYFPRLKTRRKSQAGYTSGGEQQMCAIGRAMMAKPAMILLDEPSMGLAPQIVE HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHH EIFEIVRDLNTRERVSFLLAEQNTMVALRHADYGYILENGRVVMDGDAESLRTNEDVKEF HHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCEEEECCEEEECCCHHHHCCCHHHHHH YLGVAANDADGAARKSFRDVKSYRRRKRWLA HHEEECCCCCHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure TLLSVNNIEVIYDHVILVLKGVSLEVPEGRIVALLGANGAGKTTTLKAISNLLHAERGD EEEECCCHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCC VTKGSIEYRGQRVDQLTPNDLVKRGVIQVMEGRHCFAHLTIEENLLTGAYTRGLSRGQTR CCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHCCCCCCCH DELEKIYAYFPRLKTRRKSQAGYTSGGEQQMCAIGRAMMAKPAMILLDEPSMGLAPQIVE HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHH EIFEIVRDLNTRERVSFLLAEQNTMVALRHADYGYILENGRVVMDGDAESLRTNEDVKEF HHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCEEEECCEEEECCCHHHHCCCHHHHHH YLGVAANDADGAARKSFRDVKSYRRRKRWLA HHEEECCCCCHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]