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The map label for this gene is paaK [H]

Identifier: 94309165

GI number: 94309165

Start: 234054

End: 235316

Strand: Direct

Name: paaK [H]

Synonym: Rmet_0220

Alternate gene names: 94309165

Gene position: 234054-235316 (Clockwise)

Preceding gene: 94309164

Following gene: 94309173

Centisome position: 5.96

GC content: 66.51

Gene sequence:

>1263_bases
ATGGCTGCTGATCCTGTTGAATATTTCGATGCCCTCGAGACACGCAATCCGGCCGAGCGCGAGGCGGCGCTGTTTGCCGC
CCTGGTGCGGCAGATTGCCCATGCGCAGTCGCACGCGGCTTACTTCGCGGAGATACTCTGCGACATCGACGCGCGCGACA
TCACGTCGCGTGCCGCGCTGGCGACGCTGCCGGTCACACGCAAGTCCGAAATGACCATGCAGCAGCGTATCGCGCCGCCG
TTAGGCGGCCTGAACGCGACCCCGCTGCGCGATCTGCGGCATGTGTTCCAGTCGCCGGGCCCGATCCACGAGCCCGACGG
TCATGGACCAGACTGGTGGCGCACGGCGCGCGCCATGTTCGCCGCCGGCTTCCGTGAGGGCGATCTGGTCTACAACACGT
TCTCGTACCACTTCACGCCGGCCGGCATGATGATGGAGTCGGGTGCGCACCGGCTTGGATGCTGCGTGTTTCCGGCCGGC
GTCGGGCAGACTGAGTCACAAGTGCAGGCGCTGGCCAACCTGCAGCCTTCCGCCTACGCGGGCACGCCGTCGTTCCTGAA
GCTGCTGATCGAGCGGGGCGAGGAGATGGGCATGGCGTGCTCCAGCATTTCCAAGGCGCTGGTCAGTGGCGAGGCCTGTC
CGCCCGCGCTGCGTGCCTGGCTGCAGGACCACGGCATCACCGCACGGCAGATGTATGGCACTGCCGATCTCGGCCTGATC
GCCTATGAGACCGCAGGCGGCGATGGCTGGGTGGTCGACGAGGGCGTGCTGGTCGAGATCGTCGAGCCGGGCGGCACGGA
GCCGATGCCGGAAGGCGAAGTCGGCGAGGTCGTGGTAACGGTACTTGGCAATAGCGATTACCCGTTGATCCGCTTTGGCA
CGGGCGACCTGTCGGCGATCGTGGCCGATTCATCGCATCGGGCAAGCCCGTGTGGCCGGACCAATATCCGGCTCAAGGGA
TGGCTCGGGCGCGCGGACCAGGCCACCAAGGTCAAGGGGATGTTCGTCCACCCGGGGCAGGTGGGCGATGTCGTTCGGCG
TCATGCGGAGATTCGCGCGGCGCGGCTGATCGTGACAGGCACAGTTGGGGCCGATGTGATGACGCTCCATTGCGACGTCA
CGCGCGAAGACGAGGCGCTGGCGGCGGCCATCCGCGAATCCATGCGTGAAGTCCTGCGGCTGCGGGGCGAAGTCCGCTTC
GTGCCGGCAGGATCGCTGCCGCAGGATGGCAAGGTGATCGAGGATGCGCGTAGTTACGACTGA

Upstream 100 bases:

>100_bases
TGGCCGCCAACGATGCGGATGGTGCCGCGCGCAAGTCGTTCCGCGATGTGAAGAGCTACCGCCGCCGCAAGCGCTGGCTG
GCGTGAACACAAGACAGACC

Downstream 100 bases:

>100_bases
CTACGACTGACGTGTGCCGACCCGCGCGGCCGCCTGATCCGCACGCTGGATCATTCCGGCTGCGCGTTGCTGCTCCGCAC
ATGGCCACCGCGAGGCCGCG

Product: Phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MAADPVEYFDALETRNPAEREAALFAALVRQIAHAQSHAAYFAEILCDIDARDITSRAALATLPVTRKSEMTMQQRIAPP
LGGLNATPLRDLRHVFQSPGPIHEPDGHGPDWWRTARAMFAAGFREGDLVYNTFSYHFTPAGMMMESGAHRLGCCVFPAG
VGQTESQVQALANLQPSAYAGTPSFLKLLIERGEEMGMACSSISKALVSGEACPPALRAWLQDHGITARQMYGTADLGLI
AYETAGGDGWVVDEGVLVEIVEPGGTEPMPEGEVGEVVVTVLGNSDYPLIRFGTGDLSAIVADSSHRASPCGRTNIRLKG
WLGRADQATKVKGMFVHPGQVGDVVRRHAEIRAARLIVTGTVGADVMTLHCDVTREDEALAAAIRESMREVLRLRGEVRF
VPAGSLPQDGKVIEDARSYD

Sequences:

>Translated_420_residues
MAADPVEYFDALETRNPAEREAALFAALVRQIAHAQSHAAYFAEILCDIDARDITSRAALATLPVTRKSEMTMQQRIAPP
LGGLNATPLRDLRHVFQSPGPIHEPDGHGPDWWRTARAMFAAGFREGDLVYNTFSYHFTPAGMMMESGAHRLGCCVFPAG
VGQTESQVQALANLQPSAYAGTPSFLKLLIERGEEMGMACSSISKALVSGEACPPALRAWLQDHGITARQMYGTADLGLI
AYETAGGDGWVVDEGVLVEIVEPGGTEPMPEGEVGEVVVTVLGNSDYPLIRFGTGDLSAIVADSSHRASPCGRTNIRLKG
WLGRADQATKVKGMFVHPGQVGDVVRRHAEIRAARLIVTGTVGADVMTLHCDVTREDEALAAAIRESMREVLRLRGEVRF
VPAGSLPQDGKVIEDARSYD
>Mature_419_residues
AADPVEYFDALETRNPAEREAALFAALVRQIAHAQSHAAYFAEILCDIDARDITSRAALATLPVTRKSEMTMQQRIAPPL
GGLNATPLRDLRHVFQSPGPIHEPDGHGPDWWRTARAMFAAGFREGDLVYNTFSYHFTPAGMMMESGAHRLGCCVFPAGV
GQTESQVQALANLQPSAYAGTPSFLKLLIERGEEMGMACSSISKALVSGEACPPALRAWLQDHGITARQMYGTADLGLIA
YETAGGDGWVVDEGVLVEIVEPGGTEPMPEGEVGEVVVTVLGNSDYPLIRFGTGDLSAIVADSSHRASPCGRTNIRLKGW
LGRADQATKVKGMFVHPGQVGDVVRRHAEIRAARLIVTGTVGADVMTLHCDVTREDEALAAAIRESMREVLRLRGEVRFV
PAGSLPQDGKVIEDARSYD

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=431, Percent_Identity=25.0580046403712, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 45234; Mature: 45103

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADPVEYFDALETRNPAEREAALFAALVRQIAHAQSHAAYFAEILCDIDARDITSRAAL
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ATLPVTRKSEMTMQQRIAPPLGGLNATPLRDLRHVFQSPGPIHEPDGHGPDWWRTARAMF
EECCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
AAGFREGDLVYNTFSYHFTPAGMMMESGAHRLGCCVFPAGVGQTESQVQALANLQPSAYA
HCCCCCCCEEEEEEEEEECCHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCC
GTPSFLKLLIERGEEMGMACSSISKALVSGEACPPALRAWLQDHGITARQMYGTADLGLI
CCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCEE
AYETAGGDGWVVDEGVLVEIVEPGGTEPMPEGEVGEVVVTVLGNSDYPLIRFGTGDLSAI
EEEECCCCCEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCEEEE
VADSSHRASPCGRTNIRLKGWLGRADQATKVKGMFVHPGQVGDVVRRHAEIRAARLIVTG
EECCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHEEEEEEEE
TVGADVMTLHCDVTREDEALAAAIRESMREVLRLRGEVRFVPAGSLPQDGKVIEDARSYD
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
AADPVEYFDALETRNPAEREAALFAALVRQIAHAQSHAAYFAEILCDIDARDITSRAAL
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ATLPVTRKSEMTMQQRIAPPLGGLNATPLRDLRHVFQSPGPIHEPDGHGPDWWRTARAMF
EECCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
AAGFREGDLVYNTFSYHFTPAGMMMESGAHRLGCCVFPAGVGQTESQVQALANLQPSAYA
HCCCCCCCEEEEEEEEEECCHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCC
GTPSFLKLLIERGEEMGMACSSISKALVSGEACPPALRAWLQDHGITARQMYGTADLGLI
CCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCEE
AYETAGGDGWVVDEGVLVEIVEPGGTEPMPEGEVGEVVVTVLGNSDYPLIRFGTGDLSAI
EEEECCCCCEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCEEEE
VADSSHRASPCGRTNIRLKGWLGRADQATKVKGMFVHPGQVGDVVRRHAEIRAARLIVTG
EECCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHEEEEEEEE
TVGADVMTLHCDVTREDEALAAAIRESMREVLRLRGEVRFVPAGSLPQDGKVIEDARSYD
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]