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The map label for this gene is qor [H]

Identifier: 94309142

GI number: 94309142

Start: 205268

End: 206251

Strand: Direct

Name: qor [H]

Synonym: Rmet_0197

Alternate gene names: 94309142

Gene position: 205268-206251 (Clockwise)

Preceding gene: 94309141

Following gene: 94309145

Centisome position: 5.23

GC content: 67.38

Gene sequence:

>984_bases
ATGCCAACCACCGTCCGCGCCGTCCGCCTTCACGAATTTGGTTTGCCGCAAGTGATGCGGCTCGAGTCCGTCGAATTGCC
GCCACCAGCGGCGGGCGAGGCGCGCGTGCGGCATACCGCAATCGGTTTCAATTTCATCGACGTCTACCAGCGGCGCGGCA
CCTATCCACTGCCGGTCGGCACGGGTCTGGGCCATGAGGCCGCCGGCGTGGTCGAGGCGATTGGCGATGGTGTGACCGAT
GTCGCGGTCGGCGATCGCGTGGCCTACATGAACGCCGGACTCGGCGCCTACGCCGAAGGGCGCAATATCCCCGTGGACAA
GCTTGTGAAGCTGCCGGATGCGATCAGCGACGAGCAGGCCGCGGCCGTGATCTTCAAGGGCATGACCGCGCAGTACCTGG
TCCGCCATACCTACGCGGTGAAGCCGGGCGACACGGTACTCGTGCACGCGGCGGCAGGGGGCGTCGGGCAGATCCTGAGT
GGCTGGGCGAAGGCGCTGGGCGCCCGCGTGATCGGCACGGCCGGGTCGGCGGCAAAATGCGAAATTGCCCGCGCCGTGGG
ATGCGACGTCGCGATCGACTACAGCCATGGCGATTGGGTCAAGCAGGTGCGTGACGCCACCGATGGGCGCGGCGTGAACG
TAGTCTATGACGCCGTGGGCAAGGACACCTTCCTCGGCTCGCTCGATTGCGCGCAGACCTTCGGCATGGTGGTGCTCTAC
GGCGGCGCGTCCGGCCCGGCGCCTGCCATCGAGCCCGAGTTGCTCAACAAGAAGGGCTGCCTGTACCTGACGCGACCCTC
GGTGTTCCCGCACAACGCTGATGCAACACGTTTCCGCGCCAATGCGAAGGACCTGTTCGATGCCATCGCCGCCGGTCACG
TGAAGGTCCAGATTGGCGCGCGCTTTCCGCTGGCGGACGTGGCGCGCGCGCACGAGGCTGCCGAAGGCCGGGCGACTACC
GGCGCGATCCTGCTGCTGCCCTGA

Upstream 100 bases:

>100_bases
TGTGCTGCGAACTGGCCTGAGTGACTTGGGCGTCGGCAGGATTCCGCAAAAGCGTCAATAATCGGGTCTCCGCAATTCGT
ACGAGCATCGAGGAGCCCCC

Downstream 100 bases:

>100_bases
GTGACCTGAGCGGGTTTGCCGCCTAGTGACGGTGGCCGCGATGCGCCGCGTGGCCATCGTGGCCGTCTCGGCCATCGTCG
CATTGATTGATTTCGACGCT

Product: quinone oxidoreductase, NADPH-dependent

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPTTVRAVRLHEFGLPQVMRLESVELPPPAAGEARVRHTAIGFNFIDVYQRRGTYPLPVGTGLGHEAAGVVEAIGDGVTD
VAVGDRVAYMNAGLGAYAEGRNIPVDKLVKLPDAISDEQAAAVIFKGMTAQYLVRHTYAVKPGDTVLVHAAAGGVGQILS
GWAKALGARVIGTAGSAAKCEIARAVGCDVAIDYSHGDWVKQVRDATDGRGVNVVYDAVGKDTFLGSLDCAQTFGMVVLY
GGASGPAPAIEPELLNKKGCLYLTRPSVFPHNADATRFRANAKDLFDAIAAGHVKVQIGARFPLADVARAHEAAEGRATT
GAILLLP

Sequences:

>Translated_327_residues
MPTTVRAVRLHEFGLPQVMRLESVELPPPAAGEARVRHTAIGFNFIDVYQRRGTYPLPVGTGLGHEAAGVVEAIGDGVTD
VAVGDRVAYMNAGLGAYAEGRNIPVDKLVKLPDAISDEQAAAVIFKGMTAQYLVRHTYAVKPGDTVLVHAAAGGVGQILS
GWAKALGARVIGTAGSAAKCEIARAVGCDVAIDYSHGDWVKQVRDATDGRGVNVVYDAVGKDTFLGSLDCAQTFGMVVLY
GGASGPAPAIEPELLNKKGCLYLTRPSVFPHNADATRFRANAKDLFDAIAAGHVKVQIGARFPLADVARAHEAAEGRATT
GAILLLP
>Mature_326_residues
PTTVRAVRLHEFGLPQVMRLESVELPPPAAGEARVRHTAIGFNFIDVYQRRGTYPLPVGTGLGHEAAGVVEAIGDGVTDV
AVGDRVAYMNAGLGAYAEGRNIPVDKLVKLPDAISDEQAAAVIFKGMTAQYLVRHTYAVKPGDTVLVHAAAGGVGQILSG
WAKALGARVIGTAGSAAKCEIARAVGCDVAIDYSHGDWVKQVRDATDGRGVNVVYDAVGKDTFLGSLDCAQTFGMVVLYG
GASGPAPAIEPELLNKKGCLYLTRPSVFPHNADATRFRANAKDLFDAIAAGHVKVQIGARFPLADVARAHEAAEGRATTG
AILLLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=29.7872340425532, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=29.7872340425532, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=30.7692307692308, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI24308257, Length=244, Percent_Identity=34.0163934426229, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=27.4626865671642, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=27.4626865671642, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI28557745, Length=223, Percent_Identity=31.390134529148, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI67078404, Length=324, Percent_Identity=26.8518518518519, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI226056130, Length=251, Percent_Identity=27.4900398406374, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226059159, Length=251, Percent_Identity=27.4900398406374, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226059133, Length=251, Percent_Identity=27.4900398406374, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790485, Length=325, Percent_Identity=46.4615384615385, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI226510941, Length=228, Percent_Identity=28.9473684210526, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=217, Percent_Identity=31.7972350230415, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17556000, Length=260, Percent_Identity=28.4615384615385, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=330, Percent_Identity=34.5454545454545, Blast_Score=179, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34175; Mature: 34044

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTVRAVRLHEFGLPQVMRLESVELPPPAAGEARVRHTAIGFNFIDVYQRRGTYPLPVG
CCCCEEEEEEHHCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCC
TGLGHEAAGVVEAIGDGVTDVAVGDRVAYMNAGLGAYAEGRNIPVDKLVKLPDAISDEQA
CCCCCHHHHHHHHHCCCCCCHHCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCHH
AAVIFKGMTAQYLVRHTYAVKPGDTVLVHAAAGGVGQILSGWAKALGARVIGTAGSAAKC
EEEEECCCHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCHH
EIARAVGCDVAIDYSHGDWVKQVRDATDGRGVNVVYDAVGKDTFLGSLDCAQTFGMVVLY
HHHHHCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCEECCCHHHHHCCEEEEE
GGASGPAPAIEPELLNKKGCLYLTRPSVFPHNADATRFRANAKDLFDAIAAGHVKVQIGA
CCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCCCHHEECCHHHHHHHHHCCEEEEEECC
RFPLADVARAHEAAEGRATTGAILLLP
CCCHHHHHHHHHHHCCCCCCCEEEEEC
>Mature Secondary Structure 
PTTVRAVRLHEFGLPQVMRLESVELPPPAAGEARVRHTAIGFNFIDVYQRRGTYPLPVG
CCCEEEEEEHHCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCC
TGLGHEAAGVVEAIGDGVTDVAVGDRVAYMNAGLGAYAEGRNIPVDKLVKLPDAISDEQA
CCCCCHHHHHHHHHCCCCCCHHCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCHH
AAVIFKGMTAQYLVRHTYAVKPGDTVLVHAAAGGVGQILSGWAKALGARVIGTAGSAAKC
EEEEECCCHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCHH
EIARAVGCDVAIDYSHGDWVKQVRDATDGRGVNVVYDAVGKDTFLGSLDCAQTFGMVVLY
HHHHHCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCEECCCHHHHHCCEEEEE
GGASGPAPAIEPELLNKKGCLYLTRPSVFPHNADATRFRANAKDLFDAIAAGHVKVQIGA
CCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCCCHHEECCHHHHHHHHHCCEEEEEECC
RFPLADVARAHEAAEGRATTGAILLLP
CCCHHHHHHHHHHHCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]